Product Name

  • Name

    Parbendazole

  • EINECS 238-133-3
  • CAS No. 14255-87-9
  • Article Data5
  • CAS DataBase
  • Density 1.234 g/cm3
  • Solubility <0.1 g/100 mL at 18℃
  • Melting Point 255-257 °C
  • Formula C13H17N3O2
  • Boiling Point 390.33°C (rough estimate)
  • Molecular Weight 247.297
  • Flash Point
  • Transport Information
  • Appearance solid
  • Safety Moderately toxic by ingestion. Experimental teratogenic and reproductive effects. Human mutation data reported. An anthelminthic agent. When heated to decomposition it emits toxic fumes of NOx. See also CARBAMATES.
  • Risk Codes 63-22
  • Molecular Structure Molecular Structure of 14255-87-9 (Parbendazole)
  • Hazard Symbols Xn
  • Synonyms 2-Benzimidazolecarbamicacid, 5-butyl-, methyl ester (8CI);Carbamic acid, (5-butyl-1H-benzimidazol-2-yl)-,methyl ester (9CI);5-Butyl-2-(carbomethoxyamino)benzimidazole;Helatac;Helmatac;Methyl (5-butyl-1H-benzimidazol-2-yl)carbamate;Methyl5(6)-butyl-2-benzimidazolecarbamate;Methyl 5-butylbenzimidazole-2-carbamate;PBZ (fungicide);Parbendazole;SKF 29044;
  • PSA
  • LogP

Parbendazole Chemical Properties

IUPAC Name: Methyl N-(6-butyl-1H-benzimidazol-2-yl)carbamate
Synonyms: 5-Butyl-2-benzimidazolecarbamic acid methyl ester ; 5-Butyl-2-(carbomethoxyamino)benzimidazole
Molecular Structure:
Molecular Formula : C13H17N3O2
Molecular Weight : 247.30
CAS NO: 14255-87-9
EINECS: 238-133-3
Mol File: 14255-87-9.mol
Melting point: 255-257 ºC
Index of Refraction: 1.631
Surface Tension: 54.5 dyne/cm
Density: 1.234 g/cm3
Water solubility : <0.1 g/100 mL at 18 ºC
Stability: 5-Butyl-2-benzimidazolecarbamic acid methyl ester (CAS NO.14255-87-9) is stable,incompatible with strong oxidizing agents.
Appearance:  5-Butyl-2-benzimidazolecarbamic acid methyl ester (CAS NO.14255-87-9) is crystals or fine white powder.

Parbendazole Uses

  5-Butyl-2-benzimidazolecarbamic acid methyl ester (CAS NO.14255-87-9) is used as pharmaceutical intermediate.

Parbendazole Toxicity Data With Reference

1.    

oms-hmn:leu 1 mg/L

     THERAP    Therapie. 31 (1976),505.
2.    

oms-dom:leu 1 mg/L

     THERAP    Therapie. 31 (1976),505.
3.    

orl-mus LD50:1700 mg/kg

     BSVMA8    Bulletin de la Societe des Sciences Veterinaires et de Medecine Compare de Lyon. 77 (1975),379.
4.    

orl-dom LDLo:660 mg/kg

     AUVJA2    Australian Veterinary Journal. 46 (1970),297.

Parbendazole Safety Profile

Moderately toxic by ingestion. Experimental teratogenic and reproductive effects. Human mutation data reported. An anthelminthic agent. When heated to decomposition it emits toxic fumes of NOx. See also CARBAMATES.

Parbendazole Specification

1.Air & Water Reactions：Insoluble in water.
2.Reactivity Profile： Parbendazole is a carbamate ester-amine. Amines behave as chemical bases. Carbamates are chemically similar to, but more reactive than amides. Like amides they form polymers such as polyurethane resins. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen is produced by the combination of active metals or nitrides with carbamates. Strongly oxidizing acids, peroxides, and hydroperoxides are incompatible with carbamates.
3.Health Hazard ：Acute/Chrnoic hazards : When heated to decomposition Parbendazole emits toxic fumes.
4.Fire Hazard ：Flash point data for Parbendazole are not available; however, Parbendazole is probably combustible.

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