Product Name

  • Name

    PENBUTOLOL SULFATE (200 MG)

  • EINECS 253-906-5
  • CAS No. 38363-32-5
  • Density g/cm3
  • Solubility
  • Melting Point 216-218℃ (Decomposition)
  • Formula C18H29NO2•1/2H2O4S
  • Boiling Point 438.2°Cat760mmHg
  • Molecular Weight 340.47
  • Flash Point 218.8°C
  • Transport Information
  • Appearance
  • Safety Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx and SOx.
  • Risk Codes
  • Molecular Structure Molecular Structure of 38363-32-5 (PENBUTOLOL SULFATE (200 MG))
  • Hazard Symbols
  • Synonyms Penbutolol sulfate (JP14/USP);1-(tert-Butylamino)-3-(o-cyclopentylphenoxy)propan-2-ol;Levatol (TN);PENBUTOLOL;2-Propanol, 1-(2-cyclopentylphenoxy)-3-((1,1-dimethylethyl)amino)-;Levatol;2-Propanol,1-(2-cyclopentylphenoxy)-3-[(1,1- dimethylethyl)amino]-,(S)-,sulfate (2:1) (salt);(2S)-1-(2-cyclopentylphenoxy)-3-(tert-butylamino)propan-2-ol;(2R)-1-(2-cyclopentylphenoxy)-3-(tert-butylamino)propan-2-ol; sulfuric acid;(?)-1-(tert-BUTYLAMINO)-3-(o-CYCLOPENTYLPHENOXYL)-2-PROPANOL SULFATE;HOE 893D;(?)-TERBUCLOMINE;
  • PSA 41.49000
  • LogP 3.86290

Penbutolol sulfate Chemical Properties

Product Name: Penbutolol sulfate (CAS NO.38363-32-5)


Molecular Formula: C36H60N2O8S
Molecular Weight: 680.9352g/mol
Mol File: 38363-32-5.mol
Boiling point: 438.2 °C at 760 mmHg
Flash Point: 218.8 °C
Enthalpy of Vaporization: 73.25 kJ/mol
Vapour Pressure: 1.87E-08 mmHg at 25°C
H-Bond Donor: 6
H-Bond Acceptor: 10
Structure Descriptors of Penbutolol sulfate (CAS NO.38363-32-5):
  IUPAC Name: (2R)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol; sulfuricacid
  Canonical SMILES: CC(C)(C)NCC(COC1=CC=CC=C1C2CCCC2)O.CC(C)(C)NC(COC1=CC=CC=C1C2CCCC2)O.OS(=O)(=O)O
  Isomeric SMILES: CC(C)(C)NC[C@H](COC1=CC=CC=C1C2CCCC2)O.CC(C)(C)NC[C@H](COC1=CC=CC=C1C2CCCC2)O.OS(=O)(=O)O
  InChI: InChI=1S/2C18H29NO2.H2O4S/c2*1-18(2,3)19-12-15(20)13-21-17-11-7-6-10-16(17)14-8-4-5-9-14;1-5(2,3)4/h2*6-7,10-11,14-15,19-20H,4-5,8-9,12-13H2,1-3H3;(H2,1,2,3,4)/t2*15-;/m11./s1 
  InChIKey: FEDSNBHHWZEYTP-QQPYHFHTSA-N

Penbutolol sulfate Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral 384mg/kg (384mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 16, Pg. 590, 1985.
mouse LD50 intraperitoneal 71mg/kg (71mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: CYANOSIS		 Oyo Yakuri. Pharmacometrics. Vol. 21, Pg. 1001, 1981.
mouse LD50 intravenous 38mg/kg (38mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: CYANOSIS		 Oyo Yakuri. Pharmacometrics. Vol. 21, Pg. 1001, 1981.
mouse LD50 oral 1230mg/kg (1230mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: CYANOSIS		 Oyo Yakuri. Pharmacometrics. Vol. 21, Pg. 1001, 1981.
mouse LD50 subcutaneous 405mg/kg (405mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: CYANOSIS		 Oyo Yakuri. Pharmacometrics. Vol. 21, Pg. 1001, 1981.
rabbit LD50 intravenous 17mg/kg (17mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 16, Pg. 590, 1985.
rabbit LD50 oral 297mg/kg (297mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 16, Pg. 590, 1985.
rat LD50 intraperitoneal 76mg/kg (76mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: CYANOSIS		 Oyo Yakuri. Pharmacometrics. Vol. 21, Pg. 1001, 1981.
rat LD50 intravenous 26mg/kg (26mg/kg)   Yakkyoku. Pharmacy. Vol. 36, Pg. 657, 1985.
rat LD50 oral 1350mg/kg (1350mg/kg)   Yakkyoku. Pharmacy. Vol. 36, Pg. 657, 1985.
rat LD50 subcutaneous 860mg/kg (860mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: CYANOSIS		 Oyo Yakuri. Pharmacometrics. Vol. 21, Pg. 1001, 1981.

Penbutolol sulfate Safety Profile

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx and SOx.

Penbutolol sulfate Specification

 Penbutolol sulfate , its CAS NO. is 38363-32-5, the synonyms are Penbutolol ; (-)-1-(tert-Butylamino)-3-(o-cyclopentylphenoxyl)-2-propanol sulfate ; (-)-Terbuclomine ; (S)-1-(2-Cyclopentylphenoxy)-3-((1,1-dimethylethyl)amino)-2-
propanol sulfate (2:1) (salt) ; (S)-1-(tert-Butylamino)-3-(o-cyclopentylphenoxy)-2-propanol sulfate (2:1) (salt) ; 2-Propanol, 1-(2-cyclopentylphenoxy)-3-((1,1-dimethylethyl)amino)-, (S)-, sulfate (2:1) (salt) ; CCRIS 1108 ; EINECS 253-906-5 ; HOE 39-893d ; HOE 893d ; Levatol ; UNII-US71433228 ; (S)-Bis(di-tert-butyl(3-(2-cyclopentylphenoxy)-2-
hydroxypropyl)ammonium) sulphate .

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