Phenetidine supplier | CasNO.156-43-4

Name
Phenetidine
EINECS 205-855-5
CAS No. 156-43-4
Article Data148
CAS DataBase
Density 1.037 g/cm³
Solubility practically insoluble in water
Melting Point 2-5 °C(lit.)
Formula C₈H₁₁NO
Boiling Point 254 °C at 760 mmHg
Molecular Weight 137.181
Flash Point 110.3 °C
Transport Information UN 2311
Appearance colourless liquid
Safety 28-36/37-45-46
Risk Codes 23/24/25-33-68-43-36-20/21/22
Molecular Structure
Hazard Symbols T,Xi,Xn
Synonyms p-Phenetidine(8CI);1-Amino-4-ethoxybenzene;4-Aminophenetole;4-Ethoxyaniline;4-Ethoxybenzenamine;4-Ethoxyphenylamine;4-Phenetidine;NSC 3116;p-Aminophenetole;p-Ethoxyaniline;p-Ethoxyphenylamine;p-Phenetidin;
PSA 35.25000
LogP 2.24870

Synthetic route

: 100-29-8
1-ethoxy-4-nitrobenzene

: 156-43-4
4-Ethoxyaniline

Conditions

Conditions	Yield
With hydrogen In 2-methyltetrahydrofuran; water at 40℃; under 15001.5 Torr; for 24h; chemoselective reaction;	99%
With sodium sulfide; tetrabutylammomium bromide In water; toluene at 80℃; for 0.75h; Zinin reduction;	98.4%
With hydrogen; triethylamine In ethanol; water at 110℃; under 30003 Torr; for 24h; Autoclave;	96%

: 4792-83-0, 51437-64-0
4,4'-diethoxyazoxybenzene

: 156-43-4
4-Ethoxyaniline

Conditions

Conditions	Yield
With N-doped TiO2 In methanol at 20℃; for 3h; UV-irradiation; Inert atmosphere;	99%

: 75-00-3
chloroethane

: 123-30-8
4-amino-phenol

: 156-43-4
4-Ethoxyaniline

Conditions

Conditions	Yield
With sodium hydroxide; dimethyl sulfoxide	90.1%

: 103861-73-0
N-allyl-p-phenetidine

: 156-43-4
4-Ethoxyaniline

Conditions

Conditions	Yield
With polymethylhydrosiloxane; zinc(II) chloride; tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran at 20℃;	88%

: 141-52-6
sodium ethanolate

: 540-37-4
p-aminoiodobenzene

: 156-43-4
4-Ethoxyaniline

Conditions

Conditions	Yield
With hemicucurbituril supported [Bmim]Cl In toluene for 10h; Reflux;	80%

: 74-96-4
ethyl bromide

: 123-30-8
4-amino-phenol

: 156-43-4
4-Ethoxyaniline

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; for 24h;	78%
With sodium hydride In acetonitrile at 20℃; for 24h;

: 141-52-6
sodium ethanolate

: 106-47-8
4-chloro-aniline

: 156-43-4
4-Ethoxyaniline

Conditions

Conditions	Yield
With hemicucurbituril supported [Bmim]Cl In toluene for 9h; Reflux;	75%

: 141-52-6
sodium ethanolate

: 106-40-1
4-bromo-aniline

: 156-43-4
4-Ethoxyaniline

Conditions

Conditions	Yield
With hemicucurbituril supported [Bmim]Cl In toluene for 10h; Reflux;	75%

: 75-00-3
chloroethane

: 111-96-6
diethylene glycol dimethyl ether

: 123-30-8
4-amino-phenol

: 90-04-0
2-methoxy-phenylamine

: 156-43-4
4-Ethoxyaniline

Conditions

Conditions	Yield
With sodium methylate In methanol	72.1%

...Expand

: 136353-33-8
3-Benzyl-2-[(Z)-4-ethoxy-phenylimino]-6-methyl-2,3-dihydro-6H-thiazolo[4,5-d]pyridazin-7-one

A: 72666-76-3
2-Oxothiazolo<4,5-d>pyridazin-7(6H)-one

B: 156-43-4
4-Ethoxyaniline

Conditions

Conditions	Yield
With hydrogenchloride In ethanol for 48h; Heating;	A 62% B n/a

: 103-73-1
Phenetole

A: 156-43-4
4-Ethoxyaniline

B: 94-70-2
ortho-phenitidine

Conditions

Conditions	Yield
With O-(4-nitrobenzoyl)hydroxylammonium trifluoromethanesulfonate; iron(II) bromide; silver(I) triflimide In 2,2,2-trifluoroethanol; water at 30℃; for 2h;	A 51.5% B 24.5%

: 100-66-3
methoxybenzene

A: 90-04-0
2-methoxy-phenylamine

B: 156-43-4
4-Ethoxyaniline

Conditions

Conditions	Yield
With O-(4-nitrobenzoyl)hydroxylammonium trifluoromethanesulfonate; iron(II) bromide; silver(I) triflimide In 2,2,2-trifluoroethanol; water at 30℃; for 2h; Reagent/catalyst; Solvent;	A 30.4% B 45.6%

: 125908-30-7
1-methyl-6-(4'-ethoxyphenyl)-2,5-dithiobiurea

A: 68161-60-4
2-(4'-ethoxyphenylamino)-Δ2-1,3,4-thiadiazoline-5-thione

B: 156-43-4
4-Ethoxyaniline

C: 74-89-5
methylamine

D: 13625-51-9
4-methyl-[1,2,4]triazolidine-3,5-dithione

Conditions

Conditions	Yield
With sodium hydroxide In water Heating;	A 41% B n/a C n/a D 32%

...Expand

: 125908-34-1
1-ethyl-6-(4'-ethoxyphenyl)-2,5-dithiobiurea

A: 68161-60-4
2-(4'-ethoxyphenylamino)-Δ2-1,3,4-thiadiazoline-5-thione

B: 75-04-7
ethylamine

C: 156-43-4
4-Ethoxyaniline

D: 13625-52-0
4-ethyl-[1,2,4]triazolidine-3,5-dithione

Conditions

Conditions	Yield
With sodium hydroxide In water Heating;	A 41% B n/a C n/a D 32%

...Expand

: 136353-34-9
2-[(E)-4-Ethoxy-phenylimino]-3,5-dimethyl-3,5-dihydro-2H-thiazolo[4,5-d]pyridazin-4-one

A: 136353-55-4
3,5-Dimethyl-3,5-dihydro-thiazolo[4,5-d]pyridazine-2,4-dione

B: 156-43-4
4-Ethoxyaniline

Conditions

Conditions	Yield
With hydrogenchloride In ethanol for 48h; Heating;	A 41% B n/a

: 123-30-8
4-amino-phenol

: 75-03-6
ethyl iodide

: 156-43-4
4-Ethoxyaniline

Conditions

Conditions	Yield
Stage #1: 4-amino-phenol With sodium hydride In N,N-dimethyl-formamide at 20℃; for 0.5h; Stage #2: ethyl iodide In N,N-dimethyl-formamide at 20℃; for 20h; Further stages.;	36%

: 109-63-7
boron trifluoride diethyl etherate

: 123-30-8
4-amino-phenol

: 156-43-4
4-Ethoxyaniline

Conditions

Conditions	Yield
at 120℃; Reflux;	17%

: 74-96-4
ethyl bromide

: 588-53-4
4-benzylidenamino-phenol

: 156-43-4
4-Ethoxyaniline

Conditions

Conditions	Yield
With sodium hydroxide; ethanol at 100℃; und Erhitzen des entstandenen Benzal-p-phenetidins mit ueberschuessiger Salzsaeure oder Schwefelsaeure;

: 622-61-7
1-chloro-4-ethoxybenzene

: 156-43-4
4-Ethoxyaniline

Conditions

Conditions	Yield
With diethyl ether; ammonia; potassium amide
With ammonia; potassium amide; Petroleum ether
With copper(I) oxide; ammonia; water at 225℃;

: 19063-13-9
(4-ethoxy-phenyl)-amidosulfuric acid

: 156-43-4
4-Ethoxyaniline

Conditions

Conditions	Yield
With potassium hydroxide

: 3-(4-ethoxy-anilino)-3-hydroxylamino-camphor

A: 663-17-2, 5338-41-0, 13854-86-9, 13854-87-0, 22472-58-8, 31571-14-9, 103833-77-8
(1R,4S)-3-hydroxyimino-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one

B: 156-43-4
4-Ethoxyaniline

Conditions

Conditions	Yield
3-<4-ethoxy-anilino>-3-hydroxylamino-d-camphor;

: 103861-73-0
N-allyl-p-phenetidine

A: 187737-37-7
propene

B: 156-43-4
4-Ethoxyaniline

Conditions

Conditions	Yield
at 270℃;

: 83013-75-6
(4-ethoxy-phenyl)-carbamic acid benzyl ester

: 156-43-4
4-Ethoxyaniline

Conditions

Conditions	Yield
With hydrogenchloride; palladium Hydrogenation;

: (2-ethoxy-[1]naphthyl)-(4-ethoxy-phenyl)-diazene

A: 118-30-9
2-ethoxynaphthalen-1-amine

B: 156-43-4
4-Ethoxyaniline

Conditions

Conditions	Yield
Reduktion;

: 64-17-5
ethanol

: 98-95-3
nitrobenzene

: 156-43-4
4-Ethoxyaniline

Conditions

Conditions	Yield
With sulfuric acid; magnesium

: 98-95-3
nitrobenzene

A: 106-47-8
4-chloro-aniline

B: 156-43-4
4-Ethoxyaniline

Conditions

Conditions	Yield
With hydrogenchloride; ethanol; magnesium

: 57-13-6
urea

: 740-80-7
N,N'-bis-(4-ethoxy-phenyl)-urea

: 71-36-3
butan-1-ol

A: 150-69-6
N-(p-ethoxyphenyl)urea

B: (4-ethoxy-phenyl)-carbamic acid butyl ester

C: 156-43-4
4-Ethoxyaniline

...Expand

: 64-17-5
ethanol

: 622-37-7
Phenyl azide

: 156-43-4
4-Ethoxyaniline

Conditions

Conditions	Yield
With sulfuric acid

: 588-52-3
4,4'-diethoxyazoxybenzene

: 156-43-4
4-Ethoxyaniline

Conditions

Conditions	Yield
With nickel at 200℃; under 25742.8 Torr; Hydrogenation;
With iron; acetic acid
With hydrogenchloride; tin
With manganese oxide; nickel(II) carbonate; basic copper carbonate powder at 180℃; under 7600 Torr; Hydrogenation.Reagens 4: Decalin;

: 766-39-2
2,3-Dimethylmaleic anhydride

: 156-43-4
4-Ethoxyaniline

: 1-(4-ethoxyphenyl)-3,4-dimethyl-1H-pyrrole-2,5-dione

Conditions

Conditions	Yield
In dimethyl sulfoxide at 120℃; for 16h;	100%
With ethanol

: 100-52-7
benzaldehyde

: 156-43-4
4-Ethoxyaniline

: 15484-91-0
N-benzylidene-4-ethoxyaniline

Conditions

Conditions	Yield
With aluminum oxide for 5h; Milling;	100%
In ethanol for 1h; Sonication;	100%
With magnesium sulfate; acetic acid In dichloromethane at 20℃; for 18h; Inert atmosphere;	73%

: 103-71-9
phenyl isocyanate

: 156-43-4
4-Ethoxyaniline

: 4345-85-1
1-(4-ethoxy-phenyl)-3-phenyl urea

Conditions

Conditions	Yield
In tetrahydrofuran for 0.166667h;	100%
With diethyl ether

: 120-14-9
3,4-dimethoxy-benzaldehyde

: 156-43-4
4-Ethoxyaniline

: 82363-25-5
(3,4-dimethoxybenzylidene)(4-ethoxyphenyl)amine

Conditions

Conditions	Yield
In toluene Heating;	100%
In ethanol Heating;	94%
at 110℃;

: 590-28-3
potassium cyanate

: 156-43-4
4-Ethoxyaniline

: 150-69-6
N-(p-ethoxyphenyl)urea

Conditions

Conditions	Yield
With acetic acid at 20℃; for 3h;	100%
With acetic acid In water at 20℃; for 3h;	100%
With acetic acid at 20℃;

: 67-66-3
chloroform

: 156-43-4
4-Ethoxyaniline

: 67-64-1
acetone

: 74262-33-2
α-p-phenetidino-isobutyric acid p-phenetidide

Conditions

Conditions	Yield
With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride In dichloromethane at 5℃;	100%

...Expand

: 24424-99-5
di-tert-butyl dicarbonate

: 156-43-4
4-Ethoxyaniline

: 59255-66-2
N-(tert-butoxycarbonyl)-4-ethoxyaniline

Conditions

Conditions	Yield
With guanidine hydrochloride In ethanol at 35 - 40℃; for 0.1h;	100%
In tetrahydrofuran for 2.5h; Heating;	98%
With pyridinium trifluroacetate In neat (no solvent) at 20℃; for 0.0166667h; Green chemistry;	93%

: 14770-40-2
<2-(13)C>acetyl chloride

: 156-43-4
4-Ethoxyaniline

: ([2-13C]acetyl)phenacetin

Conditions

Conditions	Yield
In benzene at 5℃; for 0.166667h;	100%

: 28228-81-1
bis(p-methoxyphenyl)methylenecyclopropane

: 100-52-7
benzaldehyde

: 156-43-4
4-Ethoxyaniline

: 4,4-bis-(4-methoxyphenyl)-2-phenyl-6-ethoxy-1,2,3,4-tetrahydrospiro-(3,1'-cyclopropyl)-quinoline

Conditions

Conditions	Yield
Stage #1: benzaldehyde; 4-Ethoxyaniline With magnesium sulfate In acetonitrile at 20℃; for 2h; Stage #2: bis(p-methoxyphenyl)methylenecyclopropane; Montmorillonite KSF In acetonitrile at 20℃; for 48h; aza-Diels-Alder reaction; Further stages.;	100%

...Expand

: 156-43-4
4-Ethoxyaniline

: 108-95-2
phenol

: (E)-4-((4-ethoxyphenyl)diazenyl)phenol

Conditions

Conditions	Yield
Stage #1: 4-Ethoxyaniline With hydrogenchloride In water; acetone at 20℃; for 0.5h; Stage #2: With sodium nitrite In water; acetone at 0℃; for 0.5h; Stage #3: phenol With sodium carbonate; sodium hydroxide In water; acetone at 0℃; for 1h;	100%
Stage #1: 4-Ethoxyaniline With hydrogenchloride; sodium nitrite In ethanol; water at 0℃; for 1h; Stage #2: phenol With sodium hydroxide In ethanol; water at 5℃; for 1.5h;	76%
Stage #1: 4-Ethoxyaniline With hydrogenchloride; sodium nitrite In ethanol; water Cooling with ice; Stage #2: phenol With sodium hydroxide In ethanol; water for 1.5h; pH=1; Cooling;

: 66-99-9
β-naphthaldehyde

: 156-43-4
4-Ethoxyaniline

: C19H17NO

Conditions

Conditions	Yield
In ethanol for 1h; Sonication;	100%

: 1520-57-6
[1-13C]acetyl chloride

: 156-43-4
4-Ethoxyaniline

: ([1-13C]acetyl)phenacetin

Conditions

Conditions	Yield
In benzene at 5℃; for 0.166667h;	99.9%

: 50-00-0
formaldehyd

: 156-43-4
4-Ethoxyaniline

: 3154-18-5
N-methyl-p-phenetidine

Conditions

Conditions	Yield
With hydrogen; potassium hydroxide; silver(l) oxide In methanol at 125℃; under 26252.6 Torr; for 4h; Concentration; Autoclave;	99.4%
With hydrogenchloride

: 463-71-8
thiophosgene

: 156-43-4
4-Ethoxyaniline

: 3460-49-9
1-ethoxy-4-isothiocyanatobenzene

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran at 25℃; for 12h;	99%
With sodium hydroxide; chloroform

: 1017609-56-1
1-benzyl-6-chloroindolin-2,3-dione

: 10277-93-7
2-isopropenylphenol

: 156-43-4
4-Ethoxyaniline

: 1416217-36-1
1-benzyl-6-chloro-6'-ethoxy-4'-(2-hydroxyphenyl)-4'-methyl-3',4'-dihydro-1'H-spiro[indoline-3,2'-quinolin]-2-one

Conditions

Conditions	Yield
With (R)-3,3'-bis(2,4,6-triisopropylphenyl)-1,1'-binaphthyl-2,2'-diylhydrogenphosphate In toluene at -20℃; Molecular sieve; enantioselective reaction;	99%

...Expand

: N-[3-[(5-bromo-2-chloropyrimidin-4-yl)amino]propyl]-N-methylcyclobutanecarboxamide

: 156-43-4
4-Ethoxyaniline

: N-[3-({5-bromo-2-[(4-ethoxyphenyl)amino]pyrimidin-4-yl}-amino)propyl]-N-methylcyclobutanecarboxamide

Conditions

Conditions	Yield
With hydrogenchloride In 1,4-dioxane; butan-1-ol at 120℃; for 0.666667h; Microwave irradiation;	99%

: 5-chloro-2-((4-chlorobenzyl)oxy)benzaldehyde

: 156-43-4
4-Ethoxyaniline

: N-(5-chloro-2-((4-chlorobenzyl)oxy)benzyl)-4-ethoxyaniline

Conditions

Conditions	Yield
Stage #1: 5-chloro-2-((4-chlorobenzyl)oxy)benzaldehyde; 4-Ethoxyaniline With acetic acid In methanol at 20℃; Inert atmosphere; Stage #2: With sodium cyanoborohydride In methanol Inert atmosphere;	98.1%

: 3282-30-2
pivaloyl chloride

: 156-43-4
4-Ethoxyaniline

: 97528-32-0
N-(4-ethoxyphenyl)pivalamide

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 0 - 20℃;	98%

: 98-88-4
benzoyl chloride

: 156-43-4
4-Ethoxyaniline

: 15437-14-6
N-(4-ethoxyphenyl)benzamide

Conditions

Conditions	Yield
With triethylamine In ethyl acetate at 0 - 20℃; for 4h;	98%
With toluene
With tetralin

: 156-43-4
4-Ethoxyaniline

: 207220-30-2
6-chloro-2-iodo-9-isopropyl-9H-purine

: (2-iodo-9-isopropyl-9H-purin-6-yl)(4-ethoxyphenyl)amine

Conditions

Conditions	Yield
With triethylamine In ethanol at 50℃; Substitution;	98%

: 82-43-9
1,8-dichloroanthraquinone

: 156-43-4
4-Ethoxyaniline

: 1,8-bis(4-ethoxyphenylamino)anthraquinone

Conditions

Conditions	Yield
With caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; bis(dibenzylideneacetone)-palladium(0) In 1,4-dioxane for 24h; Heating;	98%

: 95-72-7
2-chloro-1,4-dimethyl-benzene

: 156-43-4
4-Ethoxyaniline

: 1070664-20-8
N-(4-ethoxyphenyl)-2,5-dimethylaniline

Conditions

Conditions	Yield
With dicyclohexyl-(2′,4′,6′-triisopropyl-3,6-dimethoxy-[1,1′-biphenyl]-2-yl)phosphine; chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2’,4’,6’-triisopropyl-1,1’-biphenyl] [2-(2-aminoethyl)phenyl]palladium(II); sodium t-butanolate In dibutyl ether; toluene at 110℃; for 1h; Inert atmosphere;	98%
With sodium t-butanolate; dicyclohexyl-(2′,4′,6′-triisopropyl-3,6-dimethoxy-[1,1′-biphenyl]-2-yl)phosphine; C8H10ClNPd In dibutyl ether at 110℃; for 1h; Product distribution / selectivity; Inert atmosphere;	98%

: 464-05-1
pyridinium trifluroacetate

: 156-43-4
4-Ethoxyaniline

: 457-53-4
N-(4-ethoxyphenyl)-2,2,2-trifluoroacetamide

Conditions

Conditions	Yield
In 5,5-dimethyl-1,3-cyclohexadiene for 2h; Reflux;	98%

: 2942-59-8
2-chloronicotinic acid

: 156-43-4
4-Ethoxyaniline

: 4394-10-9
2-[(4-ethoxyphenyl)amino]pyridine-3-carboxylic acid

Conditions

Conditions	Yield
With potassium carbonate In water at 150℃; for 1.5h; Green chemistry;	98%
With potassium carbonate In water at 150℃; for 1h; Microwave irradiation;	86%

: 1314117-72-0
ethyl 2-(2-oxo-2-phenylethoxy)-4,5,6,7-tetrahydro-[1]-benzothiophene-3-carboxylate

: 156-43-4
4-Ethoxyaniline

: 1314117-94-6
C25H23NO3S

Conditions

Conditions	Yield
In acetic anhydride; acetic acid for 18h; Reflux;	98%

: 1414375-55-5
5-ethoxycarbonyl-2,6-dimethyl-3-pyridinecarboxylic acid azide

: 156-43-4
4-Ethoxyaniline

: 891028-10-7
C19H23N3O4

Conditions

Conditions	Yield
In benzene for 1h; Reflux;	98%

: 107-31-3
Methyl formate

: 156-43-4
4-Ethoxyaniline

: 61587-14-2
N-(4-ethoxyphenyl)formamide

Conditions

Conditions	Yield
With calcium(II) bis(trifluoromethanesulfonyl)imide In neat (no solvent) at 115℃; for 1h; Reagent/catalyst; Microwave irradiation; Sealed tube;	98%

: 4637-24-5
N,N-dimethyl-formamide dimethyl acetal

: 156-43-4
4-Ethoxyaniline

: 2350-63-2
Ε-N'-(4-ethoxyphenyl)-N,N-dimethylformamidine

Conditions

Conditions	Yield
In dichloromethane at 20℃; for 5h; Concentration; Solvent;	98%

Phenetidine Chemical Properties

The molecular structure of Phenetidine (CAS NO.156-43-4):

IUPAC Name: 4-Ethoxyaniline
Molecular Weight: 137.17904 g/mol
Molecular Formula: C₈H₁₁NO
Density: 1.037 g/cm³
Melting Point: 2-5 °C(lit.)
Boiling Point: 254 °C at 760 mmHg
Flash Point: 110.3 °C
Index of Refraction: 1.544
Molar Refractivity: 41.8 cm³
Molar Volume: 132.2 cm³
Surface Tension: 38.5 dyne/cm
Enthalpy of Vaporization: 49.14 kJ/mol
Vapour Pressure: 0.0177 mmHg at 25 °C
Water Solubility: practically insoluble
Sensitive: air sensitive
XLogP3: 1.2
H-Bond Donor: 1
H-Bond Acceptor: 2
Rotatable Bond Count: 2
Exact Mass: 137.084064
MonoIsotopic Mass: 137.084064
Topological Polar Surface Area: 35.2
Heavy Atom Count: 10
Canonical SMILES: CCOC1=CC=C(C=C1)N
InChI: InChI=1S/C8H11NO/c1-2-10-8-5-3-7(9)4-6-8/h3-6H,2,9H2,1H3
InChIKey: IMPPGHMHELILKG-UHFFFAOYSA-N
EINECS: 205-855-5
Product Categories: INORGANIC & ORGANIC CHEMICALS; Phenetole; Anilines (Building Blocks for Liquid Crystals); Building Blocks for Liquid Crystals; Functional Materials

Phenetidine Uses

Phenetidine (CAS NO.156-43-4) is used as intermediates of medicine, dyes, food preservatives, feed additives and rubber antioxidant.

Phenetidine Toxicity Data With Reference

1.	skn-rbt 500 mg MLD	FCTOD7 Food and Chemical Toxicology. 20 (1982),563.
2.	eye-rbt 100 mg MOD	FCTOD7 Food and Chemical Toxicology. 20 (1982),563.
3.	eye-rbt 100 mg/45 rns MLD	FCTOD7 Food and Chemical Toxicology. 20 (1982),563.
4.	mma-sat 1 µmol/plate	CPBTAL Chemical and Pharmaceutical Bulletin. 33 (1985),2877.
5.	dni-ham:lng 160 µmol/L	MUTAEX Mutagenesis. 3 (1988),51.
6.	orl-rat LD50:580 mg/kg	GISAAA Gigiena i Sanitariya. 35 (8)(1970),28.
7.	ihl-rat LCLo:250 mg/m³	GISAAA Gigiena i Sanitariya. 35 (8)(1970),28.
8.	orl-mus LD50:530 mg/kg	GTPZAB Gigiena Truda i Professionalnye Zabolevaniia. Labor Hygiene and Occupational Diseases. 25 (8)(1981),50.
9.	ipr-mus LD50:692 mg/kg	JMCMAR Journal of Medicinal Chemistry. 17 (1974),900.

Phenetidine Consensus Reports

Reported in EPA TSCA Inventory.

Phenetidine Safety Profile

Hazard Codes: Toxic T, Irritant Xi, Harmful Xn
Risk Statements: 23/24/25-33-68-43-36-20/21/22
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.
R33:Danger of cumulative effects.
R68:Possible risk of irreversible effects.
R43:May cause sensitization by skin contact.
R36:Irritating to eyes.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 28-36/37-45-46
S28:After contact with skin, wash immediately with plenty of soap-suds.
S36/37:Wear suitable protective clothing and gloves.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S46:If swallowed, seek medical advice immediately and show this container or label.
RIDADR: UN 2311 6.1/PG 3
WGK Germany: 1
RTECS: SI6465500
F: 8-10
Hazard Note: Irritant
HazardClass: 6.1
PackingGroup: III
HS Code: 29222200
Poison by inhalation. Moderately toxic by ingestion and intraperitoneal routes. Caution: It can be absorbed through the skin. A skin and eye irritant. Mutation data reported. When heated to decomposition it emits toxic fumes of NO_x.

Phenetidine Specification

Phenetidine (CAS NO.156-43-4) is also named as 1-Amino-4-ethoxybenzene ; 4-13-00-01017 (Beilstein Handbook Reference) ; 4-Aminoethoxybenzene ; 4-Aminophenetole ; 4-Ethoxyaniline ; 4-Ethoxybenzenamine ; AI3-09042 ; Aniline, p-ethoxy- ; BRN 0606666 ; CCRIS 2878 ; CP 5685 ; NSC 3116 ; p-Aminofenetol ; p-Aminofenetol [Czech] ; p-Aminophenetole ; p-Ethoxyaniline ; p-Fenetidin ; p-Fenetidin [Czech] ; p-Phenetidin ; p-Phenetidine . Phenetidine (CAS NO.156-43-4) is colourless liquid. It is slightly soluble in water. It is very sensitive to exposure to air and light. It can turn red to brown on exposure to light and air. Phenetidine reacts vigorously with powerful oxidizers. It is combustible.

Product Name

Phenetidine

Synthetic route

Phenetidine Chemical Properties

Phenetidine Uses

Phenetidine Toxicity Data With Reference

Phenetidine Consensus Reports

Phenetidine Safety Profile

Phenetidine Specification

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