Product Name

  • Name

    Pidotimod

  • EINECS 2017-001-1
  • CAS No. 121808-62-6
  • Article Data2
  • CAS DataBase
  • Density 1.53 g/cm3
  • Solubility
  • Melting Point 194-198 °C
  • Formula C9H12N2O4S
  • Boiling Point 663 °C at 760 mmHg
  • Molecular Weight 244.271
  • Flash Point 354.8 °C
  • Transport Information
  • Appearance Almost white to white crystalline powder
  • Safety
  • Risk Codes
  • Molecular Structure Molecular Structure of 121808-62-6 (Pidotimod)
  • Hazard Symbols
  • Synonyms 4-Thiazolidinecarboxylicacid, 3-[(5-oxo-2-pyrrolidinyl)carbonyl]-, [R-(R*,S*)]-;Adimod;Axil;Onaka;Pigitil;Polimod;
  • PSA 112.01000
  • LogP -0.48220

Pidotimod Specification

The IUPAC name of Pidotimod is (4R)-3-[(2S)-5-oxopyrrolidine-2-carbonyl]-1,3-thiazolidine-4-carboxylic acid. With the CAS registry number 121808-62-6, it is also named as (R)-3-((S)-(5-Oxo-2-pyrrolidinyl)carbonyl)-thiazolidin-4-carbonsaeure. The classification code is Drug / Therapeutic Agent. It is almost white to white crystalline powder which is an immunostimulant.

The other characteristics of this product can be summarized as: (1)ACD/LogP: -2.38; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -4.67; (4)ACD/LogD (pH 7.4): -6; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 6; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 2; (12)Index of Refraction: 1.619; (13)Molar Refractivity: 56.16 cm3; (14)Molar Volume: 160 cm3; (15)Polarizability: 22.26×10-24 cm3; (16)Surface Tension: 72.3 dyne/cm; (17)Enthalpy of Vaporization: 106.35 kJ/mol; (18)Vapour Pressure: 2.7E-19 mmHg at 25°C; (19)Rotatable Bond Count: 2; (20)Tautomer Count: 3; (21)Exact Mass: 244.051778; (22)MonoIsotopic Mass: 244.051778; (23)Topological Polar Surface Area: 112; (24)Heavy Atom Count: 16; (25)Complexity: 346; (26)Defined Atom StereoCenter Count: 2.

People can use the following data to convert to the molecule structure.
1. SMILES:O=C(O)[C@H]2N(C(=O)[C@H]1NC(=O)CC1)CSC2
2. InChI:InChI=1/C9H12N2O4S/c12-7-2-1-5(10-7)8(13)11-4-16-3-6(11)9(14)15/h5-6H,1-4H2,(H,10,12)(H,14,15)/t5-,6-/m0/s1 

The following are the toxicity data which has been tested.

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intramuscular > 2gm/kg (2000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 44, Pg. 1448, 1994.
dog LD50 intravenous > 2gm/kg (2000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 44, Pg. 1448, 1994.
dog LD50 oral > 4gm/kg (4000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 44, Pg. 1448, 1994.
mouse LD50 intramuscular > 4gm/kg (4000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 44, Pg. 1448, 1994.
mouse LD50 intraperitoneal 3700mg/kg (3700mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 44, Pg. 1448, 1994.
mouse LD50 intravenous > 4gm/kg (4000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 44, Pg. 1448, 1994.
mouse LD50 oral > 8gm/kg (8000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 44, Pg. 1448, 1994.
rat LD50 intramuscular > 4gm/kg (4000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 44, Pg. 1448, 1994.
rat LD50 intraperitoneal 5800mg/kg (5800mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 44, Pg. 1448, 1994.
rat LD50 intravenous > 4gm/kg (4000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 44, Pg. 1448, 1994.
rat LD50 oral > 8gm/kg (8000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 44, Pg. 1448, 1994.

Related Products

Hot Products

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View