Product Name

  • Name

    Pirprofen

  • EINECS
  • CAS No. 31793-07-4
  • Article Data4
  • CAS DataBase
  • Density 1.298g/cm3
  • Solubility
  • Melting Point 98-100°
  • Formula C13H14 Cl N O2
  • Boiling Point 410.8°Cat760mmHg
  • Molecular Weight 251.713
  • Flash Point 202.2°C
  • Transport Information
  • Appearance
  • Safety Poison by ingestion and intravenous routes. When heated to decomposition it emits toxic fumes of Cl− and NOx.
  • Risk Codes
  • Molecular Structure Molecular Structure of 31793-07-4 (Pirprofen)
  • Hazard Symbols
  • Synonyms Hydratropicacid, 3-chloro-4-(3-pyrrolin-1-yl)- (8CI); (?à)-Pirprofen; 2-[3-Chloro-4-(2,5-dihydropyrrol-1-yl)-phenyl]propanoicacid; 2-[3-Chloro-4-(3-pyrrolin-1-yl)phenyl]propionic acid;3-Chloro-4-(3-pyrrolin-1-yl)hydratropic acid; Pirprofen; Racemic pirprofen;Rangasil 400; Rengasil; Seflenyl; Su 21524
  • PSA 40.54000
  • LogP 2.96930

Pirprofen Chemical Properties

Empirical Formula: C13H14ClNO2
Molecular Weight: 251.7088 g/mol
EINECS: 250-805-8 
Index of Refraction: 1.604
Density: 1.298 g/cm3
Flash Point: 202.2 °C
Enthalpy of Vaporization: 69.93 kJ/mol
Boiling Point: 410.8 °C at 760 mmHg
Vapour Pressure: 1.74E-07 mmHg at 25 °C
Structure of Pirprofen (CAS NO.31793-07-4):
          
IUPAC Name of Pirprofen (CAS NO.31793-07-4): 2-[3-Chloro-4-(2,5-dihydropyrrol-1-yl)phenyl]propanoic acid
 

Pirprofen Uses

 Pirprofen (CAS NO.31793-07-4) has been used as a non-steroidal anti-inflammatory drug.

Pirprofen Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral 193mg/kg (193mg/kg)   Archives of Toxicology, Supplement. Vol. 7, Pg. 365, 1984.
hamster LD50 oral 1190mg/kg (1190mg/kg)   Archives of Toxicology, Supplement. Vol. 7, Pg. 365, 1984.
mouse LD50 intraperitoneal 1300mg/kg (1300mg/kg)   Russian Pharmacology and Toxicology Vol. 49, Pg. 98, 1986.
mouse LD50 oral 1350mg/kg (1350mg/kg)   Archives of Toxicology, Supplement. Vol. 7, Pg. 365, 1984.
rat LD50 intravenous 167mg/kg (167mg/kg) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE
GASTROINTESTINAL: ULCERATION OR BLEEDING FROM LARGE INTESTINE		 Current Therapeutic Research, Clinical & Experimental. Vol. 30(Suppl,
rat LD50 oral 351mg/kg (351mg/kg) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE
GASTROINTESTINAL: ULCERATION OR BLEEDING FROM LARGE INTESTINE		 Current Therapeutic Research, Clinical & Experimental. Vol. 30(Suppl,
women LDLo oral 864mg/kg/54D- (864mg/kg) BEHAVIORAL: COMA
LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE"
LIVER: "JAUNDICE, OTHER OR UNCLASSIFIED"		 Netherlands Journal of Medicine. Vol. 37, Pg. 32, 1990.
women LDLo oral 3488mg/kg/31W (3488mg/kg) LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE" Gastroenterology. Vol. 89, Pg. 210, 1985.
women TDLo oral 4624mg/kg/41W (4624mg/kg) LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE" Gastroenterology. Vol. 89, Pg. 210, 1985.
 

Pirprofen Safety Profile

Poison by ingestion and intravenous routes. When heated to decomposition it emits toxic fumes of Cl− and NOx.

Pirprofen Specification

 Pirprofen ,its cas register number is 31793-07-4. It also can be called Pirprofeno ; Pirprofenum ; Rengasil ; and 3-Chloro-4-(2,5-dihydro-1H-pyrrol-1-yl)-a-methylbenzeneacetic Acid .

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