Product Name

  • Name

    Polaprezinc

  • EINECS 600-848-7
  • CAS No. 107667-60-7
  • Article Data2
  • CAS DataBase
  • Density
  • Solubility
  • Melting Point 300 ºC
  • Formula C9H12N4O3Zn
  • Boiling Point 557.6oC at 760 mmHg
  • Molecular Weight 289.609
  • Flash Point 291oC
  • Transport Information
  • Appearance White to pale-yellow crystalline solid
  • Safety
  • Risk Codes
  • Molecular Structure Molecular Structure of 107667-60-7 (Polaprezinc)
  • Hazard Symbols
  • Synonyms Zinc,[N-b-alanyl-L-histidinato(2-)-N,NN,Oa]-;L-Histidine, N-b-alanyl-, zinc complex;Promac;Promac (antiulcer agent);Z 103;Zinc L-carnosine;b-Alanyl-L-histidinato zinc;
  • PSA 101.31000
  • LogP -0.39430

Polaprezinc Chemical Properties

IUPAC Name: Zinc(2R)-2-[(3-amino-1-oxidopropylidene)amino]-3-(1H-imidazol-5-yl)propanoate
The MF of Polaprezinc (CAS NO.107667-60-7) is C9H12N4O3Zn.

                         
The MW of Polaprezinc (CAS NO.107667-60-7) is 289.62558.
Synonyms of Polaprezinc (CAS NO.107667-60-7): Histidine, beta-alanyl-, zinc salt ; zinc 2-(beta-Alanylamino)-3-(imidazol-3-id-4-yl)propanoate ; Zinc carnosine
Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals
Apperance: White To Pale-Yellow Crystalline Solid
Melting Point: >300 °C

Polaprezinc Uses

  Polaprezinc (CAS NO.107667-60-7) is used as A novel anti-gastric ulcer agent and a new dietary supplement approved by the federal agency.

Polaprezinc Toxicity Data With Reference

1.    

orl-rat LD50:7375 mg/kg

     ARZNAD    Arzneimittel-Forschung. Drug Research. 41 (1991),1033.
2.    

ipr-rat LD50:405 mg/kg

     ARZNAD    Arzneimittel-Forschung. Drug Research. 41 (1991),1033.
3.    

scu-rat LD50:>5 g/kg

     ARZNAD    Arzneimittel-Forschung. Drug Research. 41 (1991),1033.
4.    

orl-mus LD50:1269 mg/kg

     ARZNAD    Arzneimittel-Forschung. Drug Research. 41 (1991),1033.
5.    

ipr-mus LD50:165 mg/kg

     ARZNAD    Arzneimittel-Forschung. Drug Research. 41 (1991),1033.
6.    

scu-mus LD50:758 mg/kg

     ARZNAD    Arzneimittel-Forschung. Drug Research. 41 (1991),1033.
7.    

orl-dog LD:>200 mg/kg

     ARZNAD    Arzneimittel-Forschung. Drug Research. 45 (1995),52.
8.    

orl-mky LD:>626 mg/kg

     ARZNAD    Arzneimittel-Forschung. Drug Research. 43 (1993),562.

Polaprezinc Safety Profile

A poison by intraperitoneal route. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic vapors of NOx and Zn.

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