Prostaglandin E2 supplier | CasNO.363-24-6

Name
Prostaglandin E2
EINECS 206-656-6
CAS No. 363-24-6
Article Data32
CAS DataBase
Density 1.148 g/cm³
Solubility ethanol: 1 mg/mL
Melting Point 66-68 °C
Formula C₂₀H₃₂O₅
Boiling Point 530.1 °C at 760 mmHg
Molecular Weight 352.471
Flash Point 288.5 °C
Transport Information
Appearance white to pale yellowish-cream powder
Safety 53-22-26-36/37/39
Risk Codes 60-22
Molecular Structure
Hazard Symbols T
Synonyms 5-Heptenoicacid, 7-[3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]- (8CI);(-)-Prostaglandin E2;(15S)-Prostaglandin E2;11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid (5Z,11a,13E,15S);11a,15a-Dihydroxy-9-oxo-5-cis,13-trans-prostadienoic acid;Cervidil;Cerviprime;Dinoprostone;Enzaprost E;Minprositin E2;NSC 196514;PGE2;Primiprost;Prostaglandin E2;Prostenon;Prostenone;Prostin (prostaglandin);U 12062;Vivelle-Dot;l-Prostaglandin E2;
PSA 94.83000
LogP 3.25110

Prostaglandin E2 Chemical Properties

Molecular Formula:C₂₀H₃₂O₅
Molecular Weight:352.52
EINECS:206-656-6
Density:1.148g/cm³
Melting Point:66-68°C
Boiling Point:530.1°Cat760mmHg
Flash Point:288.5°C
Solubility:insoluble
Properties:Crystals

Dinoprostone's Synonyms: Prostaglandin E2;9-OXO-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID;7-[3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]-5-heptenoic acid;(5Z,11A,13E,15S)-11,15-DIHYDROXY-9-OXO-PROSTA-5,13-DIEN-1OIC ACID;[5Z,11ALPHA,13E,15S]-11,15-DIHYDROXY-9-OXOPROSTA-5,13-DIEN-1-OIC ACID;[5Z,11ALPHA,13E,15S]-11,15-DIHYDROXY-9-OXOPROSTA-5,13-DIENOIC ACID;PROSTAGLANDIN;PROSTAGLANDIN E2

Prostaglandin E2 Uses

Induction of labor

Prostaglandin E2 Toxicity Data With Reference

1.	oms-mus:oth 100 nmol/L	JIDEAE Journal of Investigative Dermatology. 66 (1976),313.
2.	spm-mus-ipr 3 mg/kg	INJFA3 International Journal of Fertility. 21 (1976),82.
3.	dns-gpg:lng 1 mg/L	PSEBAA Proceedings of the Society for Experimental Biology and Medicine. 171 (1982),109.
4.	orl-rat LD50:500 mg/kg	OYYAA2 Oyo Yakuri. Pharmacometrics. 8 (1974),787.
5.	scu-rat LD50:31,600 µg/kg	OYYAA2 Oyo Yakuri. Pharmacometrics. 8 (1974),787.
6.	ivn-rat LD50:59,500 µg/kg	OYYAA2 Oyo Yakuri. Pharmacometrics. 8 (1974),787.
7.	orl-mus LD50:750 mg/kg	OYYAA2 Oyo Yakuri. Pharmacometrics. 8 (1974),787.
8.	scu-mus LD50:19,700 µg/kg	OYYAA2 Oyo Yakuri. Pharmacometrics. 8 (1974),787.
9.	ivn-mus LD50:23,200 µg/kg	OYYAA2 Oyo Yakuri. Pharmacometrics. 8 (1974),787.
10.	ipr-ham LD50:1 mg/kg	PLMEDD Prostaglandins, Leukotrienes and Medicine. 17 (1985),309.

Prostaglandin E2 Safety Profile

Poison by subcutaneous and intravenous routes. Moderately toxic by ingestion and intraperitoneal routes. An experimental teratogen. Human reproductive effects by intravenous, intraplacental, and intravaginal routes: changes in the uterus, cervix and vagina; termination of pregnancy; and changes in fertility. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.

Dinoprostone's Safety Information
Hazard Codes T
Risk Statements 60-22
Safety Statements 53-22-26-36/37/39
WGK Germany 3
RTECS UK8000000
F 8-10

Prostaglandin E2 Specification

Dinoprostone's Handling and Storage
【Storage】Keep container closed when not in use. Deep freeze (below -20 C). Store protected from light. Store with dessicant.
【Handling】Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Store protected from light. Use only in a chemical fume hood.

Product Name

Prostaglandin E2

Prostaglandin E2 Chemical Properties

Prostaglandin E2 Uses

Prostaglandin E2 Toxicity Data With Reference

Prostaglandin E2 Safety Profile

Prostaglandin E2 Specification

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