Product Name

Stability

    Incompatible with strong oxidizing agents.

Toxicology

    No toxicological data available.

    Toxicity data
    (The meaning of any toxicological abbreviations w

  • Melting Point
  • Formula C29H32 Cl N5 O2
  • Boiling Point 657.2oC at 760 mmHg
  • Molecular Weight 518.058
  • Flash Point 351.3oC
  • Transport Information
  • Appearance solid
  • Safety Moderately toxic by ingestion. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of Cl and NOx. An antimalarial drug.
  • Risk Codes
  • Molecular Structure Molecular Structure of 74847-35-1 (Pyronaridine)
  • Hazard Symbols
  • Synonyms Benzo[b]-1,5-naphthyridine,phenol deriv.; Malaridine; Pyronaridine
  • PSA 76.72000
  • LogP 5.44880

Pyronaridine Chemical Properties

IUPAC Name: 4-[(7-Chloro-2-methoxy-1,5-dihydrobenzo[b][1,5]naphthyridin-10-yl)imino]-2,6-bis(pyrrolidin-1-ylmethyl)cyclohexa-2,5-dien-1-one
The MF of Pyronaridine (CAS NO.74847-35-1) is C29H32ClN5O2.

                
The MW of Pyronaridine (CAS NO.74847-35-1) is 518.0497.
Synonyms of Pyronaridine (CAS NO.74847-35-1): 4-[(7-Chloro-2-methoxybenzo[b]-1,5-naphthyridin-10-yl)amino]-2,6-bis(1-pyrrolidinylmethyl)phenol ; Phenol, 4-((7-chloro-2-methoxybenzo(b)-1,5-naphthyridin-10-yl)amino)-2,6-bis(1-pyrrolidinylmethyl)-
Stability: Incompatible with strong oxidizing agents
Index of Refraction: 1.719 
Apperance: solid
Density: 1.356 g/ml 
Flash Point: 329.6 °C
Boiling Point: 621.3 °C

Pyronaridine Uses

   Pyronaridine (CAS NO.74847-35-1) is an antimalarial drug. It was first synthesized in 1970 and has been in clinical use in China since the 1980s.

Pyronaridine Toxicity Data With Reference

1.    

mmo-sat 100 µg/plate

    CYLPDN    Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. 3 (1982),51.
2.    

orl-mus LD50:1100 mg/kg

    YHHPAL    Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal. 17 (1982),401.

Pyronaridine Safety Profile

Moderately toxic by ingestion. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of Cl and NOx. An antimalarial drug.

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