Ropivacaine hydrochloride hydrate supplier

Name
Ropivacaine hydrochloride
EINECS 663-286-1
CAS No. 132112-35-7
Article Data2
CAS DataBase
Density
Solubility
Melting Point 267-269 °C
Formula C₁₇H₂₉ClN₂O₂
Boiling Point 410.2 °C at 760 mmHg
Molecular Weight 328.882
Flash Point 201.9 °C
Transport Information
Appearance white solid
Safety 22-36/37/39-45
Risk Codes 26/27/28
Molecular Structure
Hazard Symbols T
Synonyms 2-Piperidinecarboxamide,N-(2,6-dimethylphenyl)-1-propyl-, monohydrochloride,monohydrate, (2S)- (9CI);2-Piperidinecarboxamide,N-(2,6-dimethylphenyl)-1-propyl-, monohydrochloride,monohydrate, (S)-;Ropivacaine hydrochloridemonohydrate;Ropivacaine HCL;(s)-n-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride;
PSA 41.57000
LogP 4.25500

Synthetic route

: 84057-95-4
ropivacaine

: 132112-35-7
ropivacaine hydrochloride monohydrate

Conditions

Conditions	Yield
With hydrogenchloride; water In acetone pH=2; Product distribution / selectivity; Heating / reflux;	82%
With hydrogenchloride; water at 0 - 85℃; for 48h; Product distribution / selectivity;	79%

: 98717-15-8
ropivacaine hydrochloride

: 132112-35-7
ropivacaine hydrochloride monohydrate

Conditions

Conditions	Yield
With water at 40℃; for 20h; Product distribution / selectivity;

Ropivacaine hydrochloride hydrate Specification

Ropivacaine hydrochloride hydrate, with the CAS NO.132112-35-7, has the Synonym of (S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride monohydrate; S-Ropivacaine Hcl; Ropivcacaine Hydrochloride; (S)-1-Propyl-2',6'-Dimethylanilinoformoxylpiperidine Monohydrochloride Monohydrate. The drug substance is a white crystalline powder, with a molecular formula of C₁₇H₂₆N₂O•HCl•H₂O, molecular weight of 328.89 and soluble in water and in ethanol (96 per cent), slightly soluble in methylene chloride. And Ropivacaine hydrochloride hydrate should be stored in cool place. Keep container tightly closed in a dry and well-ventilated place.Recommended storage temperature: 2 - 8 °C. Ropivacaine hydrochloride is used as a surgical anesthetics.

Physical properties about Ropivacaine hydrochloride hydrate are: (1)ACD/LogP: 3.105; (2)ACD/LogD (pH 5.5): 0.94; (3)ACD/LogD (pH 7.4): 2.62; (4)ACD/BCF (pH 5.5): 1.00; (5)ACD/BCF (pH 7.4): 43.75; (6)ACD/KOC (pH 5.5): 7.90; (7)ACD/KOC (pH 7.4): 377.81; (8)#H bond acceptors: 3; (9)#H bond donors: 1; (10)#Freely Rotating Bonds: 4; (11)Flash Point: 201.9 °C; (12)Enthalpy of Vaporization: 66.25 kJ/mol; (13)Boiling Point: 410.2 °C at 760 mmHg; (14)Vapour Pressure: 6.13E-07 mmHg at 25°C

When you are using this chemical, please be cautious about it as the following:
1. Do not breathe dust;
2. Wear suitable protective clothing, gloves and eye/face protection;
3. In case of accident or if you feel unwell, seek medical advice immediately (show label where possible);

You can still convert the following datas into molecular structure:
(1)InChI=1S/C17H26N2O.ClH.H2O/c1-4-11-19-12-6-5-10-15(19)17(20)18-16-13(2)8-7-9-14(16)3;;/h7-9,15H,4-6,10-12H2,1-3H3,(H,18,20);1H;1H2/t15-;;/m0../s1;
(2)InChIKey=VSHFRHVKMYGBJL-CKUXDGONSA-N; (
(3)SmilesN1([C@@H](CCCC1)C(=O)Nc1c(cccc1C)C)CCC.Cl.O

Product Name

Ropivacaine hydrochloride

Synthetic route

Ropivacaine hydrochloride hydrate Specification

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