• Name

  Satranidazole

• EINECS
• CAS No. 56302-13-7
• Article Data3
• CAS DataBase
• Density 1.77g/cm³
• Solubility
• Melting Point 185°C
• Formula C8H11 N5 O5 S
• Boiling Point 505.2°Cat760mmHg
• Molecular Weight 289.272
• Flash Point 259.3°C
• Transport Information
• Appearance
• Safety Slightly toxic by ingestion. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NO_x and SO_x.
• Risk Codes
• Molecular Structure
• Hazard Symbols
• Synonyms CG 10213Go;Go 10213; Satranidazole
• PSA 129.71000
• LogP 1.13680

Synthetic route

41730-79-4

1-(methylsulphonyl)-2-oxo-2,3,4,5-tetrahydroimidazole

1615-53-8

1-methyl-2-methylsulphonyl-5-nitro-imidazole

56302-13-7

1 (1 methyl 5 nitroimidazol 2 yl) 3 (methylsulfonyl)imidazolidin 2 one

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 25℃; for 5h;	80%

85695-00-7

1-methylsulphonyl-3-(1-methyl-2-imidazolyl)-2-imidazolidinone

56302-13-7

1 (1 methyl 5 nitroimidazol 2 yl) 3 (methylsulfonyl)imidazolidin 2 one

Conditions

Conditions	Yield
With sulfuric acid; nitric acid at 120℃; for 1.5h;	15 mg

86072-07-3

2-chloro-1-methyl-5-nitroimidazole

41730-79-4

1-(methylsulphonyl)-2-oxo-2,3,4,5-tetrahydroimidazole

56302-13-7

1 (1 methyl 5 nitroimidazol 2 yl) 3 (methylsulfonyl)imidazolidin 2 one

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide 1.) 30 min, room temperature, 2.) a) 1 h, room temperture, b) 3 h, 55 deg C, c) room temperature;	0.9 g

1-(1-methyl-imidazolyl)-2-imidazolidinone hydrochloride

56302-13-7

1 (1 methyl 5 nitroimidazol 2 yl) 3 (methylsulfonyl)imidazolidin 2 one

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 0.1 g / NaH / dimethylformamide; dioxane / 1) 0-5 deg C, 1 h, 2) RT, 12 h 2: 15 mg / conc. H2SO4, HNO3 (d 1.42) / 1.5 h / 120 °C View Scheme

368-39-8

triethyloxonium fluoroborate

56302-13-7

1 (1 methyl 5 nitroimidazol 2 yl) 3 (methylsulfonyl)imidazolidin 2 one

3-ethyl-1-methyl-5-nitro-2-(3-methylsulphonyl-2-oxotetrahydroimidazolyl-1-) imidazolium fluoroborate

Conditions

Conditions	Yield
In chloroform for 72h; Ambient temperature;	0.85 g

56302-13-7

1 (1 methyl 5 nitroimidazol 2 yl) 3 (methylsulfonyl)imidazolidin 2 one

5'-Amino-3-methanesulfonyl-1'-methyl-4,5-dihydro-3H,1'H-[1,2']biimidazolyl-2-one

Conditions

Conditions	Yield
With hydrogen; sodium sulfate; nickel In ethyl acetate; N,N-dimethyl-formamide at 45℃;
With hydrogenchloride; zinc

56302-13-7

1 (1 methyl 5 nitroimidazol 2 yl) 3 (methylsulfonyl)imidazolidin 2 one

134307-48-5

2-(2-methanesulphonamidoethylamino)-1-methyl-5-nitroimidazole

Conditions

Conditions	Yield
With hydroxide	0.1 g

56302-13-7

1 (1 methyl 5 nitroimidazol 2 yl) 3 (methylsulfonyl)imidazolidin 2 one

A

85695-08-5

1-methanesulphonyl-3-(5-nitro-1H-imidazol-2-yl)-2-imidazolidinone

B

56302-24-0

1-methanesulphonyl-3-(1-methyl-4-nitro-1H-imidazol-2-yl)-2-imidazolidinone

Conditions

Conditions	Yield
With potassium iodide In N,N-dimethyl-formamide for 20h; Heating;	A 1.8 g B 2.1 g
With potassium iodide In N,N-dimethyl-formamide Heating;

SATRANIDAZOLE Chemical Properties

Synonyms: 1-(1-Methyl-5-nitro-1H-imidazol-2-yl)-3-(methylsulfonyl)-2-imidazolidinone;CG-10213Go;Go-10213 Satranidazole;
The Molecular formula of SATRANIDAZOLE(56302-13-7): C₈H₁₁N₅O₅S
Molecular Structure :