Product Name

  • Name

    Selenomethionine

  • EINECS 215-977-0
  • CAS No. 1464-42-2
  • Article Data1
  • CAS DataBase
  • Density g/cm3
  • Solubility soluble
  • Melting Point 267-269 ºC
  • Formula C5H11 N O2 Se
  • Boiling Point 320.8°Cat760mmHg
  • Molecular Weight 196.108
  • Flash Point 147.8°C
  • Transport Information UN 3283
  • Appearance white crystalline solid
  • Safety Poison by intravenous, intraperitoneal and intracervical routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx and Se. See also AMINES and SELENIUM COMPOUNDS.
  • Risk Codes R23/25;R33;R50/53   
  • Molecular Structure Molecular Structure of 1464-42-2 (Selenomethionine)
  • Hazard Symbols
  • Synonyms Butyricacid, 2-amino-4-(methylselenyl)- (6CI,8CI);2-Amino-4-(methylseleno)butyricacid;2-Amino-4-(methylselenyl)butyric acid;DL-Selenomethionine;Seleniummethionine;Seleno-DL-methionine;Selenomethionine;
  • PSA 63.32000
  • LogP 0.65930

Selenomethionine Chemical Properties

IUPAC Name: 2-Amino-4-methylselanylbutanoic acid
The MF of Selenomethionine (CAS NO.1464-42-2) is C5H11NO2Se.

                             
The MW of Selenomethionine (CAS NO.1464-42-2) is 196.11.
Synonyms of Selenomethionine (CAS NO.1464-42-2): Butanoic acid, 2-amino-4-(methylseleno)-, (2S)- ; (2S)-2-Amino-4-(methylselanyl)butanoic acid
Product Categories: Methionine [Met, M];Amino Acids;I - Z;Modified Amino Acids
Apperance: Colorless,transparent six square lamellae with metallic luster
Flash Point: 147.8 °C
Boiling Point: 320.8 °C
Melting Point: 267-269 °C
Storage temp: -20 °C
Water Solubility: soluble
EINECS: 215-977-0

Selenomethionine Uses

 Selenomethionine (CAS NO.1464-42-2) is used as intermediates for medicine and health products and feed additives.Incorporation of selenomethionine into proteins in place of methionine aids the structure elucidation of proteins by X-ray crystallography using multi-wavelength anomalous diffraction (MAD). The incorporation of heavy atoms such as selenium helps solving the phase problem in X-ray crystallography.

Selenomethionine Toxicity Data With Reference

1.    

dns-rat:lvr 100 µmol/L

    CALEDQ    Cancer Letters (Shannon, Ireland). 10 (1980),75.
2.    

ipr-rat LD50:11 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 108 (1953),437.
3.    

ivn-mus LD50:22 mg/kg

    NRTXDN    Neurotoxicology. 2 (1981),383.
4.    

icv-mus LD50:13 mg/kg

    NRTXDN    Neurotoxicology. 2 (1981),838.
5.    

ivn-pig LDLo:7450 µg/kg

    AJVRAH    American Journal of Veterinary Research. 34 (1973),1227.

Selenomethionine Consensus Reports

Selenium and its compounds are on the Community Right-To-Know List.

Selenomethionine Safety Profile

Poison by intravenous, intraperitoneal and intracervical routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx and Se. See also AMINES and SELENIUM COMPOUNDS.Safety information of Selenomethionine (CAS NO.1464-42-2):
Hazard Codes  ToxicT,DangerousN
Risk Statements 
23/25 Toxic by inhalation and if swallowed
33 Danger of cumulative effects
50/53 Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Safety Statements 
20/21 When using, do not eat, drink or smoke
28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
45 In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
60 This material and/or its container must be disposed of as hazardous waste
61 Avoid release to the environment. Refer to special instructions safety data sheet
RIDADR  UN 3283
RTECS  ES7110000

Selenomethionine Standards and Recommendations

OSHA PEL: TWA 0.2 mg(Se)/m3
ACGIH TLV: TWA 0.2 mg(Se)/m3
DFG MAK: 0.1 mg(Se)/m3

Selenomethionine Specification

 Selenomethionine is an amino acid containing selenium. The L-isomer of selenomethionine, known as Se-met and Sem, is a common natural food source of selenium.The incorporation of selenomethionine into tissue proteins and keratin in horses causes alkali disease. Alkali disease is characterized by emaciation, loss of hair, deformation and shedding of hooves, loss of vitality and erosion of the joints of long bones.

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