Semicarbazide supplier | CasNO.57-56-7

Name
Semicarbazide
EINECS 200-339-6
CAS No. 57-56-7
Article Data110
CAS DataBase
Density 1.286±0.06 g/cm3(Predicted)
Solubility
Melting Point 175-185oC /decomposes/
Formula CH5 N3 O
Boiling Point 133.71°C (rough estimate)
Molecular Weight 75.0702
Flash Point
Transport Information
Appearance
Safety A poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. Human systemic effects by intravenous route: convulsions. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NO_x. See also HYDRAZINE.
Risk Codes 22
Molecular Structure
Hazard Symbols Xn
Synonyms Isosemicarbazide(8CI); Aminourea; Carbamic acid, hydrazide; Carbamylhydrazine; Carbazamide;Carbazimidic acid; Hydrazine, (aminocarbonyl)-; Semicarbazide; Urea, amino-
PSA 81.14000
LogP 0.31990

Semicarbazide Chemical Properties

Chemistry informtion about Semicarbazide (57-56-7) is:
IUPAC Name: Aminourea
Synonyms: Aminomocovina ; Amino-Ure ; Carbamic Acid, Hydrazide ; Carbamicacid,Hydrazide ; Carbamoyl-Hydrazin ; Carbamylhydrazine ; Carbazamide ; Hydrazine, Carbamoyl-
MF: CH₅N₃O
MW: 75.07
EINECS: 200-339-6
Density: 1.286 g/cm³
Flash Point: 66.5 °C
Boiling Point: 186.3 °C at 760 mmHg
Vapour Pressure: 0.187 mmHg at 25°C
Enthalpy of Vaporization: 49.18 kJ/mol
Following is the molecular structure of Semicarbazide (57-56-7) is:

Semicarbazide Uses

Semicarbazide (57-56-7) is used as a detection reagent on thin layer chromatography (TLC). It stains α-keto acids on the TLC plate, which must then be viewed under a UV light to see the results.

Semicarbazide Production

Raw materials: Urea → Hydrazine Sulfate → Sodium Cyanate → Semicarbazide Hydrochloride
Preparation Products: Hydrocortisone → 4'-Methylacetophenone → Semicarbazide Hydrochloride → Civetone → 2,6-Dihydroxypurine → Nitrofurantoin → Menthone → 3-Methylcyclopentadecanone → Mitoguazone → 4-Phenylurazole → Acetone Semicarbazone

Semicarbazide Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
man	TDLo	intravenous	40mg/kg (40mg/kg)	Behavioral: convulsions or effect on seizure threshold	Journal of Pharmacology and Experimental Therapeutics. Vol. 122, Pg. 110, 1958.
mouse	LD50	intraperitoneal	123mg/kg (123mg/kg)	Behavioral: convulsions or effect on seizure threshold	Journal of Pharmacology and Experimental Therapeutics. Vol. 122, Pg. 110, 1958.
mouse	LD50	intravenous	126mg/kg (126mg/kg)	Behavioral: convulsions or effect on seizure threshold	Journal of Pharmacology and Experimental Therapeutics. Vol. 122, Pg. 110, 1958.
mouse	LD50	oral	176mg/kg (176mg/kg)	Behavioral: convulsions or effect on seizure threshold	Journal of Pharmacology and Experimental Therapeutics. Vol. 122, Pg. 110, 1958.
mouse	LD50	subcutaneous	105mg/kg (105mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 119, Pg. 444, 1957.
rat	LD50	intraperitoneal	140mg/kg (140mg/kg)		Naunyn-Schmiedebergs Archiv fuer Pharmakologie und Experimentelle Pathologie. Vol. 257, Pg. 296, 1967.
rat	LD50	subcutaneous	140mg/kg (140mg/kg)

Semicarbazide Consensus Reports

Reported in EPA TSCA Inventory.

Semicarbazide Safety Profile

A poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. Human systemic effects by intravenous route: convulsions. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NO_x. See also HYDRAZINE.
Hazard Codes:
Xn: Harmful
Risk Statements:
R22: Harmful if swallowed.
Safety Statements:
S22: Do not breathe dust.
WGK Germany: 3

Product Name

Semicarbazide