Sodium diethyldithiocarbamate supplier

Name
Sodium diethyldithiocarbamate
EINECS 205-710-6
CAS No. 148-18-5
Article Data23
CAS DataBase
Density 1.086 g/cm³
Solubility water: >=10 g/100 mL at 14 °C
Melting Point 95 °C
Formula C₅H₁₀NNaS₂
Boiling Point 176.4 °C at 760 mmHg
Molecular Weight 171.263
Flash Point 60.5 °C
Transport Information
Appearance Odorless white or slightly brown or slightly pink crystals
Safety
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms Sodium N,N-diethyldithiocarbamate;Carbamic acid, diethyldithio-, sodium salt;DEDC;Soxinol ESL;Diethyldithiocarbamic acid, sodium;Usaf ek-2596;DEDK;Ditiocarb sodium;Diethyldithiocarbamic acid, sodium salt;Thiocarb;GS 694A;NCI-C02835;DTC;DDC;
PSA 60.63000
LogP 1.81060

Synthetic route

: 75-15-0
carbon disulfide

: 109-89-7
diethylamine

: 148-18-5
sodium N,N-diethyldithiocarbamate

Conditions

Conditions	Yield
With sodium hydroxide In ethanol; water cooling;	90%
With sodium hydroxide In ethanol at 20 - 40℃;	73%
With sodium hydroxide In water at 20℃; for 1h; Cooling with ice;	69%

: 97-77-8
disulfiram

: 140-90-9
sodium O-ethyl dithiocarbonate

A: 148-18-5
sodium N,N-diethyldithiocarbamate

B: 327989-09-3
C8H15NOS4

Conditions

Conditions	Yield
With sodium nitrate; C8MoN8(3-)*3Na(1+) In water; acetone at 25℃; Rate constant; Equilibrium constant; μ 0.2 mol/l;

...Expand

: 97-77-8
disulfiram

: 4092-82-4
sodium N,N'-diisopropyldithiocarbamate

A: 148-18-5
sodium N,N-diethyldithiocarbamate

B: C12H24N2S4

Conditions

Conditions	Yield
With sodium nitrate; potassium hexacyanoferrate(III) In water; acetone at 25℃; Equilibrium constant; μ 0.2 mol/l;

...Expand

: 140-90-9
sodium O-ethyl dithiocarbonate

: 327989-09-3
C8H15NOS4

A: 502-55-6
bis-ethoxythiocarbonyldisulfane

B: 148-18-5
sodium N,N-diethyldithiocarbamate

Conditions

Conditions	Yield
With sodium nitrate; C8MoN8(3-)*3Na(1+) In water; acetone at 25℃; Rate constant; Equilibrium constant; μ 0.2 mol/l;

...Expand

: 4092-82-4
sodium N,N'-diisopropyldithiocarbamate

: C12H24N2S4

A: 4136-91-8
tetraisopropylothiuram disulphide

B: 148-18-5
sodium N,N-diethyldithiocarbamate

Conditions

Conditions	Yield
With sodium nitrate; potassium hexacyanoferrate(III) In water; acetone at 25℃; Equilibrium constant; μ 0.2 mol/l;

...Expand

: 138523-63-4
Tributyltin diethyldithiocarbamate

: 148-18-5
sodium N,N-diethyldithiocarbamate

Conditions

Conditions	Yield
With sodium hydrogensulfide In methanol at 4℃;

: 80-05-7
BPA

concentrated NaOH: concentrated NaOH

: N-(hydroxyethyl)-ethylenediamine

: 112-34-5
Diethylene glycol monobutyl ether

: 120-32-1
chlorophene

: 148-18-5
sodium N,N-diethyldithiocarbamate

...Expand

: 148-18-5
sodium N,N-diethyldithiocarbamate

5'-I-d(TTT)-CPG resin: 5'-I-d(TTT)-CPG resin

: C35H49N7O18P2S2

Conditions

Conditions	Yield
Stage #1: sodium N,N-diethyldithiocarbamate; 5'-I-d(TTT)-CPG resin In N,N-dimethyl-formamide at 20℃; for 0.0333333h; Stage #2: With ammonium hydroxide at 60℃; for 17h;	100%

: [Re(S3CPh)2(S2CPh)]

: 148-18-5
sodium N,N-diethyldithiocarbamate

: bis(trithioperoxybenzoato)-(diethyldithiocarbamato)rhenium (III)

Conditions

Conditions	Yield
In methanol; dichloromethane at 20℃; for 1h;	100%

: 148-18-5
sodium N,N-diethyldithiocarbamate

: 572-09-8
2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide

: S-(2',3',4',6'-tetra-O-acetyl-β-D-glucopyranosyl) N,N-diethyldithiocarbamate

Conditions

Conditions	Yield
In acetone for 1h; Reflux;	99%
In acetonitrile at 25℃; for 1h;	63%

: bis(tetraethylammonium) tri-μ2-disulfido-μ3-thio-hexabromo-triangular-trimolybdenum(IV)

: 148-18-5
sodium N,N-diethyldithiocarbamate

: tris(diethyldithiocarbamato-S,S')tris(μ2-η(2)-disulfido)(μ3-sulfido)trimolybdenum(IV)(3 Mo-Mo) diethyldithiocarbamate

Conditions

Conditions	Yield
In solid byproducts: Et4NBr, NaBr; mixt. was evacuated at 80 °C for 2 h, mech. activation for 1.5 h in a vac. vibration mill with steel ball (23 Hz); H2O was added, ppt. was washed with hot H2O and EtOH, dried in vac. at 75 °C, residue was treated with hot MeCN, washed with H2O and EtOH, dried in vac. at 75 °C, recrystn. from DMSO, elem. anal.;	99%

: 1243627-92-0
[AuCl(2-thia-1,3,5-triaza-7-phosphaadamantane-2,2-dioxide)]

: 148-18-5
sodium N,N-diethyldithiocarbamate

: 1243628-11-6
[Au(diethyldithiocarbamate)(2-thia-1,3,5-triaza-7-phosphaadamantane-2,2-dioxide)]

Conditions

Conditions	Yield
In methanol Na salt was added to suspn. of Au complex in MeOH; stirred for 18 h; filtered; washed (H2O, MeOH, Et2O); dried in air; elem. anal.;	99%

: 148-18-5
sodium N,N-diethyldithiocarbamate

: (1R,6S)-1-Methyl-7-(toluene-4-sulfonyl)-7-aza-bicyclo[4.1.0]heptane

: C19H30N2O2S3

Conditions

Conditions	Yield
In acetonitrile at 80℃; for 12h; stereoselective reaction;	99%

: 148-18-5
sodium N,N-diethyldithiocarbamate

: 112297-29-7
7-[(4-methylphenyl)sulfonyl]-7-azabicyclo[4.1.0]hept-3-ene

: C18H26N2O2S3

Conditions

Conditions	Yield
In acetonitrile at 80℃; for 0.5h; stereoselective reaction;	99%

: 148-18-5
sodium N,N-diethyldithiocarbamate

: 121995-12-8
2-(N-acetylanilino)-4-iodomethyl-1,3-selenazole

: [2-(N-acetylanilino)-1,3-selenazol-4-ylmethyl]-N,N-diethyldithiocarbamate

Conditions

Conditions	Yield
In acetone for 0.5h; Heating;	98%

: 148-18-5
sodium N,N-diethyldithiocarbamate

: copper dichloride

: 13681-87-3
bis(N,N-diethyldithiocarbamato)copper(II)

Conditions

Conditions	Yield
In neat (no solvent, solid phase) byproducts: NaCl; placing of CuCl2 and NaS2CNEt2 in 1:2 ratio to the reactor; sealing, vibrating for 60 min; sublimating in vac. at 180-190°C; crystn.; elem. anal.;	98%

: 148-18-5
sodium N,N-diethyldithiocarbamate

: 16894-68-1
tetraphenylchloroantimony(V)

: 109423-89-4
tetraphenylantimony N,N-diethyldithiocarbamate

Conditions

Conditions	Yield
In water byproducts: NaCl; soln. of ligand in water was added to soln. of Sb-complex in water; filtered off, dried, crystd. from toluene-heptane;	98%

: 1112152-67-6
2-(bromomethyl)-1,3-thiaselenole

: 148-18-5
sodium N,N-diethyldithiocarbamate

: (Z)-2-([(diethylamino)carbothioyl]sulfanylselanyl)ethenyl vinyl sulfide

Conditions

Conditions	Yield
In acetonitrile at 20℃; for 0.0333333h; regioselective reaction;	98%

: {Mo(CPh)Br(CO)2(4-picoline)2}

: 56-34-8
tetraethylammonium chloride

: 148-18-5
sodium N,N-diethyldithiocarbamate

: {N(C2H5)4}(1+)*{Mo(S2CN(C2H5)2)2(CO)(C6H5CCO)}(1-)={N(C2H5)4}{Mo(S2CN(C2H5)2)2(CO)(C6H5CCO)}

Conditions

Conditions	Yield
In tetrahydrofuran byproducts: NaBr; under inert atm.; addn. of soln. of Na-compd. to soln. of complex at -78°C, removed from cold bath and stirred at ambient temp. for 1.45 h; evapd. (vac.), dissolved in CH2Cl2, addn. of NEt4Cl, stirred for 45 min, filtered (cellulose), dried (vac., 2.5 h), treated with THF, cooled to -8°C for 30 min, supernatant decanted, , washed (THF), recrystd. (CH2Cl2/Et2O);	97.5%

Yield

In tetrahydrofuran byproducts: NaBr; under inert atm.; addn. of soln. of Na-compd. to soln. of complex at -78°C, removed from cold bath and stirred at ambient temp. for 1.45 h; evapd. (vac.), dissolved in CH2Cl2, addn. of NEt4Cl, stirred for 45 min, filtered (cellulose), dried (vac., 2.5 h), treated with THF, cooled to -8°C for 30 min, supernatant decanted, , washed (THF), recrystd. (CH2Cl2/Et2O);

97.5%

...Expand

: 148-18-5
sodium N,N-diethyldithiocarbamate

: 7646-85-7
zinc(II) chloride

: 14324-55-1
bis(N,N-diethyldithiocarbamato)zinc(II)

Conditions

Conditions	Yield
In neat (no solvent, solid phase) byproducts: NaCl; placing of ZnCl2 and NaS2CNEt2 in 1:2 ratio to the reactor; sealing, vibrating for 10 min; sublimating at 150-165°C in vac.; crystn.; elem. anal.;	97%

: 13965-31-6
dichloro(2,2'-bipyridine)platinum(II)

: 148-18-5
sodium N,N-diethyldithiocarbamate

: 15730-38-8
bis(N,N-diethyldithiocarbamate)platinum(II)

Conditions

Conditions	Yield
In not given stoich. amts., stirring for 1 h (pptn.); collection (filtration), washing (water), drying (vac.);	97%

: 148-18-5
sodium N,N-diethyldithiocarbamate

: 5035-52-9
dichlorophenylstibine

: phenylantimony chloride diethyldithiocarbamate

Conditions

Conditions	Yield
In chloroform equimolar amts. at 25°C;	97%

: 148-18-5
sodium N,N-diethyldithiocarbamate

: 5035-52-9
dichlorophenylstibine

: 18615-16-2
phenylantimony diethyldithiocarbamate

Conditions

Conditions	Yield
In chloroform equimolar amts. of educts at 25°C;	97%

: RuCl2(CO)(P(CH3)(CH(CH3)2)2)2

: 148-18-5
sodium N,N-diethyldithiocarbamate

: RuCl(CO)(S2CN(C2H5)2)(P(CH3)(CH(CH3)2)2)2

Conditions

Conditions	Yield
In dichloromethane (inert atmosphere); stirring (12 h); filtration (Celite), solvent removal (vac.), washing (light petroleum); elem. anal.;	97%

: (±)-trans-N-tosyl-2-isopropyl-3-methylaziridine

: 148-18-5
sodium N,N-diethyldithiocarbamate

: C18H30N2O2S3

Conditions

Conditions	Yield
In acetonitrile at 80℃; for 12h; stereoselective reaction;	97%

: 68820-12-2
cyclohexyl-N-tosyl aziridine

: 148-18-5
sodium N,N-diethyldithiocarbamate

: C18H28N2O2S3

Conditions

Conditions	Yield
In acetonitrile at 80℃; for 0.166667h; stereoselective reaction;	97%

: 148-18-5
sodium N,N-diethyldithiocarbamate

: 81097-48-5
N-tosyl-6-azabicyclo[3.1.0]hexane

: C17H26N2O2S3

Conditions

Conditions	Yield
In acetonitrile at 80℃; for 1h; stereoselective reaction;	97%

: 1592-20-7
4-Vinylbenzyl chloride

: 148-18-5
sodium N,N-diethyldithiocarbamate

: N,N-(diethylamino)dithiocarbamoylmethylstyrene

Conditions

Conditions	Yield
In acetone at 40℃; for 1h;	97%

: bis(4-methyl-2-chloroacetamidothiazole)sulfide

: 148-18-5
sodium N,N-diethyldithiocarbamate

: C22H32N6O2S7

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 20℃; for 6h;	97%

: 148-18-5
sodium N,N-diethyldithiocarbamate

: 1073-05-8
1,3,2-dioxathiane 2,2-dioxide

: C13H22NO7S3(1-)*Na(1+)

Conditions

Conditions	Yield
In methanol at 20℃;	97%

: 61272-76-2
4-fluoro-2-iodoaniline

: 148-18-5
sodium N,N-diethyldithiocarbamate

: 6-fluoro-N,N-diethylbenzo[d]thiazol-2-amine

Conditions

Conditions	Yield
With copper diacetate; potassium carbonate In N,N-dimethyl-formamide at 120℃; for 6h; Sealed tube;	97%

: 148-18-5
sodium N,N-diethyldithiocarbamate

: 10108-64-2
cadmium(II) chloride

: 14239-68-0
cadmium(II) diethyldithiocarbamate

Conditions

Conditions	Yield
In neat (no solvent, solid phase) byproducts: NaCl; placing of CdCl2 and NaS2CNEt2 in 1:2 ratio to the reactor; sealing, vibrating for 60 min; sublimating in vac. at 180-230°C; crystn.; elem. anal.;	96.6%
In water byproducts: NaCl; pptn. of complex from soln. at room temp., filtration while hot, drying (80°C, vac.); recrystn. (benzene); (1)H- and (13)C-NMR;
In water byproducts: NaCl; ZnCl2, the thiocarbamate in water, immediately pptn.; filtered hot to remove NaCl and any excess of unreacted thiocarbamate, dried (vac. at 80°C), recrystn. (boiling benzene);
In water solution of CdCl2 added to stirred solution of the ligand; filtered, dried, recrystd. from chloroform;

: 148-18-5
sodium N,N-diethyldithiocarbamate

: 97-77-8
disulfiram

Conditions

Conditions	Yield
With 1,3,5-trichloro-2,4,6-triazine; dimethyl sulfoxide In dichloromethane at 20℃; for 2h;	96%
With iodine In methanol at 0℃;	95%
With oxygen; sodium hydroxide In water at 25℃; for 1.08333h; pH=10; Kinetics; pH-value; Reagent/catalyst;	94%

: 760-90-7
dimethyl 2-bromosuccinate

: 148-18-5
sodium N,N-diethyldithiocarbamate

: 94725-95-8
dimethyl (diethylthiocarbamoylthio)succinate

Conditions

Conditions	Yield
In water for 8h;	96%

: 600-00-0
ethyl 2-bromoisobutyrate

: 148-18-5
sodium N,N-diethyldithiocarbamate

: 120924-70-1
S-(1-methyl-1-ethoxycarbonylethyl) N,N-diethyl-dithiocarbamate

Conditions

Conditions	Yield
In acetone at 40℃;	96%

: 542-58-5
2-chloro-1-acetoxyethane

: 148-18-5
sodium N,N-diethyldithiocarbamate

: N,N-diethyldithiocarbamic acid 2-(acetoxy)ethyl ester

Conditions

Conditions	Yield
In acetone at 40℃;	96%
With water In N,N-dimethyl-formamide at 75 - 80℃;	88%

: 700840-90-0
3-benzyltetrahydro-1,3-oxazine-2-thione

: 148-18-5
sodium N,N-diethyldithiocarbamate

polymer, product of cationic ring-opening polymerization, Mn 20400 Da by SEC in THF, Mn 12200 by light scattering, PDI 1.04; monomer(s): 3-benzyltetrahydro-1,3-oxazine-2-thione; sodium N,N-diethyldithiocarbamate: polymer, product of cationic ring-opening polymerization, Mn 20400 Da by SEC in THF, Mn 12200 by light scattering, PDI 1.04; monomer(s): 3-benzyltetrahydro-1,3-oxazine-2-thione; sodium N,N-diethyldithiocarbamate

Conditions

Conditions	Yield
Stage #1: 3-benzyltetrahydro-1,3-oxazine-2-thione With boron trifluoride diethyl etherate In nitrobenzene at 50℃; for 24h; Stage #2: sodium N,N-diethyldithiocarbamate In nitrobenzene; acetonitrile	96%

Sodium diethyldithiocarbamate Chemical Properties

IUPAC Name: sodium N,N-diethylcarbamodithioate
Following is the structure of Sodium diethyldithiocarbamate (CAS NO.148-18-5):

Molecular formula: C₅H₁₀NNaS₂
Molecular Weight: 171.26
EINECS: 205-710-6
Melting point: 95°C
Flash Point: 60.5 °C
Index of Refraction: 1.555
Molar Refractivity: 44.12 cm³
Molar Volume: 137.3 cm³
Density: 1.086 g/cm³
Surface Tension: 44.6 dyne/cm
Boiling Point: 176.4 °C at 760 mmHg
Enthalpy of Vaporization: 41.27 kJ/mol
Vapour Pressure: 1.1 mmHg at 25 °C
Water Solubility of Sodium diethyldithiocarbamate (CAS NO.148-18-5): >=10 g/100 mL at 14 °C
Product Categories of Sodium diethyldithiocarbamate (CAS NO.148-18-5): Pharmaceutical Intermediates; Aliphatics
Canonical SMILES: CCN(CC)C(=S)[S-].[Na+]
InChI: InChI=1S/C5H11NS2.Na/c1-3-6(4-2)5(7)8;/h3-4H2,1-2H3,(H,7,8);/q;+1/p-1
InChIKey: IOEJYZSZYUROLN-UHFFFAOYSA-M

Sodium diethyldithiocarbamate Uses

Sodium diethyldithiocarbamate (CAS NO.148-18-5) can be used as a pesticide.

Sodium diethyldithiocarbamate Toxicity Data With Reference

1.	oms-omi 100 µmol/L	BBACAQ Biochimica et Biophysica Acta. 519 (1978),65.
2.	dnd-hmn:hla 100 µmol/L	BBACAQ Biochimica et Biophysica Acta. 519 (1978),65.
3.	cyt-rat-orl 5200 mg/kg	MUREAV Mutation Research. 53 (1978),212.
4.	dni-ckn:emb 4 µmol/L	BBACAQ Biochimica et Biophysica Acta. 519 (1978),65.
5.	oms-ckn:emb 40 µmol/L	BBACAQ Biochimica et Biophysica Acta. 519 (1978),65.
6.	orl-rat LD50:1500 mg/kg	DRFUD4 Drugs of the Future. 6 (1981),225.
7.	ipr-rat LD50:1250 mg/kg	DRFUD4 Drugs of the Future. 6 (1981),225.
8.	orl-mus LD50:1500 mg/kg	DRFUD4 Drugs of the Future. 6 (1981),225.
9.	ipr-mus LD50:1302 mg/kg	DRFUD4 Drugs of the Future. 6 (1981),225.
10.	scu-rbt LD50:500 mg/kg	APTOA6 Acta Pharmacologica et Toxicologica. 8 (1952),329.

Sodium diethyldithiocarbamate Consensus Reports

IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 12 ,1976,p. 217.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . NCI Carcinogenesis Bioassay (feed); No Evidence: mouse, rat NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-172 ,1979. . Reported in EPA TSCA Inventory.

Sodium diethyldithiocarbamate Safety Profile

Moderately is toxic by ingestion, intraperitoneal, and subcutaneous routes. Experimental reproductive effects. Questionable carcinogen with experimental neoplastigenic and teratogenic data. Human mutation data reported. When heated to decomposition it emits very toxic fumes of NO_x, SO_x, and Na₂O. See also CARBAMATES.

Sodium diethyldithiocarbamate Standards and Recommendations

DFG MAK: 2 mg/m³

Sodium diethyldithiocarbamate Specification

Sodium diethyldithiocarbamate , its cas register number is 148-18-5. It also can be called Diethyldithiocarbamic acid sodium salt ; N,N-Diethyldithiocarbamic acid, sodium salt ; and Sodium N,N-diethyldithiocarbamate . Its classification code are Agricultural Chemical; Antidote for nickel and cadmium poisoning; Fungicide, bactericide, wood preservative; Mutation data ; Reproductive Effect and Tumor data.

Product Name

Sodium diethyldithiocarbamate

Synthetic route

Sodium diethyldithiocarbamate Chemical Properties

Sodium diethyldithiocarbamate Uses

Sodium diethyldithiocarbamate Toxicity Data With Reference

Sodium diethyldithiocarbamate Consensus Reports

Sodium diethyldithiocarbamate Safety Profile

Sodium diethyldithiocarbamate Standards and Recommendations

Sodium diethyldithiocarbamate Specification

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