Span 80

The Sorbitan monooleate is an organic compound with the formula C₂₄H₄₄O₆. The IUPAC name of this chemical is [2-(3,4-dihydroxyoxolan-2-yl)-2-hydroxyethyl] octadec-9-enoate. With the CAS registry number 1338-43-8, it is also named as sorbitan oleate. The product's categories are Ester Type (Surfactants); Functional Materials; Nonionic Surfactants; Surfactants. Besides, it should be stored in a closed cool and dry place. It is used as emulsifier, stabilizer, thickener, wetting agent in medicine, textiles and cosmetics, and also used as dispersant, oil emulsifier in the paint industry.

Physical properties about Sorbitan monooleate are:
(1)ACD/LogP: 7.14; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): 7.14; (4)ACD/LogD (pH 7.4): 7.14; (5)#H bond acceptors: 6; (6)#H bond donors: 3; (7)#Freely Rotating Bonds: 22; (8)Polar Surface Area: 96.22 Å²; (9)Index of Refraction: 1.506; (10)Molar Refractivity: 119.22 cm³; (11)Molar Volume: 401 cm³; (12)Polarizability: 47.26×10^-24cm³; (13)Surface Tension: 44.9 dyne/cm; (14)Density: 1.068 g/cm³; (15)Flash Point: 186.2 °C; (16)Enthalpy of Vaporization: 99.52 kJ/mol; (17)Boiling Point: 579.3 °C at 760 mmHg; (18)Vapour Pressure: 7.87E-16 mmHg at 25°C.

Preparation of Span 80:
Span 80can be prepared by Sorbitan and oleic acid.


You can still convert the following datas into molecular structure:
(1)SMILES:O[C@H](COC(=O)CCCCCCCC=CCCCCCCCC)[C@H]1OC[C@H](O)[C@H]1O;
(2)Std. InChI:InChI=1S/C24H44O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(27)29-19-21(26)24-23(28)20(25)18-30-24/h9-10,20-21,23-26,28H,2-8,11-19H2,1H3/t20-,21+,23+,24+/m0/s1;
(3)Std. InChIKey:NWGKJDSIEKMTRX-XWVZOOPGSA-N.