Sulfamethoxazole supplier | CasNO.723-46-6

Name
Sulfamethoxazole
EINECS 211-963-3
CAS No. 723-46-6
Article Data24
CAS DataBase
Density 1.462 g/cm³
Solubility Soluble in ethanol or acetone. Very slightly soluble in water
Melting Point 166 °C
Formula C₁₀H₁₁N₃O₃S
Boiling Point 482.1 °C at 760 mmHg
Molecular Weight 253.282
Flash Point 245.4 °C
Transport Information
Appearance Crystals or white powder
Safety 26-36-36/37/39-22
Risk Codes 36/37/38-43-22
Molecular Structure
Hazard Symbols Xn, Xi
Synonyms Sulfanilamide,N1-(5-methyl-3-isoxazolyl)- (6CI,8CI);3-(p-Aminobenzenesulfonamido)-5-methylisoxazole;3-Sulfanilamido-5-methylisoxazole;4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide;4-Amino-N-(5-methyl-3-isoxazolyl)benzensulfonamide;5-Methyl-3-sulfanilamidoisoxazole;Gantanol;N1-(5-Methyl-3-isoxazolyl)sulfanilamide;NSC 147832;Radonil;Ro 4-2130;STX608;Sinomin;Sulfamethoxazol;
PSA 106.60000
LogP 3.10100

Synthetic route

: 21312-10-7
N-acetylsulfamethoxazole

: 723-46-6
sulfamethoxazole

Conditions

Conditions	Yield
With hydrogenchloride In methanol; diethyl ether at 75℃; for 0.25h; Microwave irradiation;	100%
Stage #1: N-acetylsulfamethoxazole With sodium hydroxide; water at 80℃; for 1h; Stage #2: With acetic acid In water pH=6;	96%
With sodium hydroxide In water for 4h; Reflux;	93%

: 1072-67-9
5-methylisoxazol-3-ylamine

: 24939-24-0
4-aminobenzenesulfonyl chloride

: 723-46-6
sulfamethoxazole

Conditions

Conditions	Yield
Stage #1: 5-methylisoxazol-3-ylamine With ammonium hydroxide at 35 - 40℃; for 1h; Large scale; Stage #2: 4-aminobenzenesulfonyl chloride at 15 - 20℃; for 4.5h; Large scale;	95%

: 1072-67-9
5-methylisoxazol-3-ylamine

: 121-60-8
p-acetylaminobenzenesulfonyl chloride

: 723-46-6
sulfamethoxazole

Conditions

Conditions	Yield
Stage #1: 5-methylisoxazol-3-ylamine; p-acetylaminobenzenesulfonyl chloride With pyridine In tetrahydrofuran at 20℃; Inert atmosphere; Stage #2: With sodium hydroxide for 2h; Inert atmosphere; Reflux;	60%
Stage #1: 5-methylisoxazol-3-ylamine; p-acetylaminobenzenesulfonyl chloride With pyridine In tetrahydrofuran at 20℃; for 6h; Stage #2: With sodium hydroxide for 2h; Reflux;

: 13053-79-7
4-amino-N-(5-methyl-3-isoxazolyl)-benzene sulfonamide

A: 723-46-6
sulfamethoxazole

B: 954563-97-4
C10H11N3O3S

C: C10H11N3O3S

Conditions

Conditions	Yield
Stage #1: 4-amino-N-(5-methyl-3-isoxazolyl)-benzene sulfonamide With tris(2,2-bipyridine)ruthenium(II) hexafluorophosphate; C8H9F3NO3S(1+)*CF3O3S(1-) In acetonitrile at 30℃; for 1h; Sealed tube; Irradiation; Stage #2: With N-butylamine In acetonitrile at 23℃; for 12h; regioselective reaction;	A 13% B 43% C 12%

...Expand

: 97254-40-5
N,N'-bis-(5-methyl-isoxazol-3-yl)-4,4'-diazenediyl-bis-benzenesulfonamide

: 723-46-6
sulfamethoxazole

Conditions

Conditions	Yield
With hydrogen; nickel In sodium hydroxide Ambient temperature;

: 13752-78-8
2-butynenitrile

: 121-60-8
p-acetylaminobenzenesulfonyl chloride

: 723-46-6
sulfamethoxazole

Conditions

Conditions	Yield
(i) NH2OH*HCl, aq. NaOH, EtOH, (ii) /BRN= 746676/, Py, (iii) aq. NaOH; Multistep reaction;

: 25109-76-6
2,3-dibromobutanenitrile

: 121-60-8
p-acetylaminobenzenesulfonyl chloride

: 723-46-6
sulfamethoxazole

Conditions

Conditions	Yield
(i) NH2CONHOH, aq. NaOH, K2CO3, (ii) /BRN= 746676/, Py, (iii) aq. NaOH; Multistep reaction;

: 29699-89-6
N-(5-methyl-isoxazol-3-yl)-4-nitro-benzenesulfonamide

: 723-46-6
sulfamethoxazole

Conditions

Conditions	Yield
With hydrogen; platinum In ethanol Ambient temperature;
Multi-step reaction with 2 steps 1: H2 / Pd-C / aq. NaOH / Ambient temperature 2: H2 / Raney-Ni / aq. NaOH / Ambient temperature View Scheme

: 128960-77-0
glutathione

: 131549-85-4
nitroso derivative of sulfamethoxazole

A: 723-46-6
sulfamethoxazole

B: 464195-31-1
glutathione disulfide

C: (S)-2-Amino-4-[(S)-1-(carboxymethyl-carbamoyl)-2-sulfino-ethylcarbamoyl]-butyric acid

D: (S)-2-Amino-4-((S)-1-(carboxymethyl-carbamoyl)-2-{N-[4-(5-methyl-isoxazol-3-ylsulfamoyl)-phenyl]aminosulfanyl}-ethylcarbamoyl)-butyric acid

E: C20H26N6O10S2

F: (S)-2-Amino-4-{(S)-1-(carboxymethyl-carbamoyl)-2-[4-(5-methyl-isoxazol-3-ylsulfamoyl)-phenylsulfinamoyl]-ethylcarbamoyl}-butyric acid

Conditions

Conditions	Yield
In dimethyl sulfoxide for 20h; Product distribution;

...Expand

: 1072-67-9
5-methylisoxazol-3-ylamine

: 6752-38-1
4-chlorosulfonylbenzene isocyanate

: 723-46-6
sulfamethoxazole

Conditions

Conditions	Yield
solid phase synthesis; Yield given. Multistep reaction;

: 114438-33-4
sulphamethoxazole hydroxylamine

: 723-46-6
sulfamethoxazole

Conditions

Conditions	Yield
With 1,4-dihydronicotinamide adenine dinucleotide; human recombinant NADH cytochrome b5 reductase; cytochrome b5 In dimethyl sulfoxide pH=7.4; Enzyme kinetics; Further Variations:; Reagents;
With nicotinamide-adenin-dinucleotide reduced; recombinant human mitochondrial amidoxime reducing component-2 wild type protein In aq. buffer at 37℃; for 0.333333h; pH=6; Kinetics; Reagent/catalyst; Enzymatic reaction;

: 121-60-8
p-acetylaminobenzenesulfonyl chloride

: 723-46-6
sulfamethoxazole

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: pyridine 2: aqueous NaOH View Scheme
Multi-step reaction with 2 steps 1: pyridine / dichloromethane / 18 h / 20 °C / Inert atmosphere 2: hydrogenchloride / diethyl ether; methanol / 0.25 h / 75 °C / Microwave irradiation View Scheme
Multi-step reaction with 2 steps 1: pyridine; dmap / 12 h / 20 °C 2: sodium hydroxide / water / 4 h / Reflux View Scheme
Multi-step reaction with 2 steps 1: potassium carbonate / acetonitrile / 2 h / Reflux 2: hydrogenchloride / water / 3 h View Scheme

: 98-74-8
4-Nitrobenzenesulfonyl chloride

: 723-46-6
sulfamethoxazole

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: pyridine / 6 h / Ambient temperature 2: H2 / Pd-C / aq. NaOH / Ambient temperature 3: H2 / Raney-Ni / aq. NaOH / Ambient temperature View Scheme
Multi-step reaction with 2 steps 1: pyridine / 6 h / Ambient temperature 2: H2 / Pt / ethanol / Ambient temperature View Scheme

: 99447-77-5
4,4'-diazenediyl-bis-benzenesulfonyl chloride

: 723-46-6
sulfamethoxazole

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: pyridine / 1 h / Heating 2: H2 / Raney-Ni / aq. NaOH / Ambient temperature View Scheme

: 103-84-4
Acetanilid

: 723-46-6
sulfamethoxazole

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: chlorosulfonic acid / 10 h / 15 - 50 °C 2.1: sodium chloride / water / 40 °C 2.2: 5 h / 25 - 38 °C / pH 4 3.1: sodium hydroxide / water / 2 h / 104 °C / pH 14 View Scheme

: 723-46-6
sulfamethoxazole

: 85100-77-2
1-n-butyl-3-methylimidazolim bromide

: 1676076-93-9
C8H15N2(1+)*C10H10N3O3S(1-)

Conditions

Conditions	Yield
Stage #1: 1-n-butyl-3-methylimidazolim bromide With Merck ion exchange resin III In water Stage #2: sulfamethoxazole In water at 20℃; for 2h;	99%

: 123-75-1
pyrrolidine

: 723-46-6
sulfamethoxazole

: C15H18N4O3S

Conditions

Conditions	Yield
Stage #1: sulfamethoxazole With hydrogenchloride; sodium nitrite Green chemistry; Stage #2: pyrrolidine With potassium hydroxide Green chemistry;	99%

: 723-46-6
sulfamethoxazole

: 811-68-7
silver(I) trifluoromethanethiolate

: 956576-66-2
4-isothiocyanato-N-(5-methylisoxazol-3-yl)benzenesulfonamide

Conditions

Conditions	Yield
With potassium bromide In acetonitrile at 20℃; for 1h;	97%

: 1226-71-7, 57427-89-1, 82301-52-8
4-(4-hydroxybenzylidene)-2-phenyloxazol-5(4H)-one

: 723-46-6
sulfamethoxazole

: 843640-21-1
C26H20N4O5S

Conditions

Conditions	Yield
Stage #1: 4-(4-hydroxybenzylidene)-2-phenyloxazol-5(4H)-one; sulfamethoxazole at 140℃; for 1h; Stage #2: In acetone for 8h; Reflux;	93%

: 723-46-6
sulfamethoxazole

: 1-octyl-3-methyl-imidazolium bromide

: 1676076-98-4
C12H23N2(1+)*C10H10N3O3S(1-)

Conditions

Conditions	Yield
Stage #1: 1-octyl-3-methyl-imidazolium bromide With Merck ion exchange resin III In water Stage #2: sulfamethoxazole In water at 20℃; for 2h;	93%

: 2631-77-8
3,5-diodosalicylaldehyde

: 723-46-6
sulfamethoxazole

: 4-[(2-hydroxy-3,5-diiodobenzylidene)amino]-N-(5-methylisoxazol-3-yl)benzenesulfonamide

Conditions

Conditions	Yield
In methanol at 20℃; for 16h; Reflux;	93%

: 723-46-6
sulfamethoxazole

: 19755-56-7
(1,1,1,3,3,3-hexafluoro-2-methylprop-2-yl)isocyanate

: 355829-57-1
1-[4-[(5-methylisoxazol-3-yl)sulfamoyl]phenyl]-3-[2,2,2-trifluoro-1-methyl-1-(trifluoromethyl)ethyl]urea

Conditions

Conditions	Yield
With triethylamine In diethyl ether; benzene at 100℃;	92%

: 444731-74-2
N-(2-chloropyrimidin-4-yl)-2,3-dimethyl-2H-indazol-6-amine

: 723-46-6
sulfamethoxazole

: 1572439-33-8
4-((4-((2,3-dimethyl-2H-indazol-6-yl)amino)pyrimidin-2-yl)amino)-N-(5-methylisoxazol-3-yl)benzenesulfonamide

Conditions

Conditions	Yield
With hydrogenchloride In water; isopropyl alcohol at 85℃;	92%

: 1-hexadecyl-3-methyl-3H-imidazol-1-ium; bromide

: 723-46-6
sulfamethoxazole

: 1676077-01-2
C20H39N2(1+)*C10H10N3O3S(1-)

Conditions

Conditions	Yield
Stage #1: 1-hexadecyl-3-methyl-3H-imidazol-1-ium; bromide With Merck ion exchange resin III In water Stage #2: sulfamethoxazole In water at 20℃; for 2h;	92%

: 110-78-1
Propyl isocyanate

: 723-46-6
sulfamethoxazole

: N-(5-methylisoxazol-3-yl)-4-(3-propylureido)benzenesulfonamide

Conditions

Conditions	Yield
In acetonitrile at 20℃; for 11.5h; Reflux;	92%

: 723-46-6
sulfamethoxazole

: 439-14-5
diazepam

: 4-([4-{7-chloro-1-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-5-yl}phenyl]diazenyl)-N-(5-methylisoxazol-3-yl)benzenesulfonamide

Conditions

Conditions	Yield
Stage #1: sulfamethoxazole With hydrogenchloride; sodium nitrite In water at 0 - 5℃; for 0.0833333h; Green chemistry; Stage #2: diazepam With sodium acetate In ethanol; water Green chemistry;	92%

: 723-46-6
sulfamethoxazole

: 1774-47-6
trimethylsulfoxonium iodide

: 51543-31-8
4-amino-N-(5-methyl-3-isoxazolyl)-N-methylbenzenesulfonamide

Conditions

Conditions	Yield
With aluminum oxide; potassium hydroxide at 130℃; for 0.0666667h; microwave irradiation;	91%

: 723-46-6
sulfamethoxazole

: 3173-56-6
benzyl isothiocyanate

: 4-(3-benzylureido)-N-(5-methylisoxazol-3-yl)benzenesulfonamide

Conditions

Conditions	Yield
In acetonitrile at 20℃; for 11.5h; Reflux;	91%
In N,N-dimethyl-formamide at 90 - 100℃;	2.12 g

: 723-46-6
sulfamethoxazole

: 4-azido-N-(5-methylisoxazol-3-yl)benzenesulfonamide

Conditions

Conditions	Yield
Stage #1: sulfamethoxazole With sulfuric acid In water at 0℃; Stage #2: With sodium nitrite In water at 0 - 20℃; for 0.166667h; Stage #3: With sodium azide; urea In water at 20℃;	91%
With sodium azide; tert.-butylnitrite In 1,4-dioxane; water at 50℃; for 0.333333h; Microwave irradiation;	82%

: 723-46-6
sulfamethoxazole

: C10H10(2)HN3O3S

Conditions

Conditions	Yield
With Kerr's catalyst; deuterium In chlorobenzene at 120℃; for 1h;	91%

: 50-00-0
formaldehyd

: 723-46-6
sulfamethoxazole

: 418790-13-3
N-(4-carbamoylphenyl)nicotinamide

: N-[4-({[4-(5-methyl-isoxazol-3-ylsulfamoyl)-phenylamino]-methyl}-carbamoyl)-phenyl]-nicotinamide

Conditions

Conditions	Yield
Stage #1: formaldehyd; N-(4-carbamoyl-phenyl)-nicotinamide With hydrogenchloride In methanol at 0℃; for 0.5h; pH=3.5; Stage #2: sulfamethoxazole Heating;	90%

...Expand

: 723-46-6
sulfamethoxazole

: 148-53-8
3-methoxy-2-hydroxybenzaldehyde

: 328026-18-2
4-(2-hydroxy-3-methoxybenzylidenamine)-N-(5-methylisoxozaol-3-yl)benzenesulfonamide

Conditions

Conditions	Yield
In tetrahydrofuran for 2h;	90%
With acetic acid In ethanol for 1h; Reflux;	81%

: 1357149-34-8
methyl 2-[4-(1H-indol-2-yl)phenoxy]acetate

: 723-46-6
sulfamethoxazole

: 1357149-22-4
2-[4-(1H-indol-2-yl)phenoxy]-N-{4-[N-(5-methylisoxazol-3-yl)sulfamoyl]phenyl}acetamide

Conditions

Conditions	Yield
With potassium carbonate In acetone for 10h;	90%

: 50899-59-7
N-Hydroxymethylisatin

: 723-46-6
sulfamethoxazole

: 1393098-78-6
4-[(1-hydroxymethyl)-2-oxindolin-3-ylideneamino]-N-(5-methylisoxazol-3-yl)benzenesulphonamide

Conditions

Conditions	Yield
In ethanol for 8h; Reflux;	90%

: 723-46-6
sulfamethoxazole

: 36140-83-7
1-cyanoacetyl-3,5-dimethylpyrazole

: 901373-59-9
2-cyano-N-(4-{[(5-methylisoxazol-3-yl)amino]sulfonyl}phenyl)acetamide

Conditions

Conditions	Yield
In toluene for 3h; Reflux;	90%
In 1,4-dioxane for 3h; Reflux;	80%

: 98885-93-9, 115851-80-4, 147556-16-9
curcumin

: 723-46-6
sulfamethoxazole

: 1443768-38-4
3,5-disulfamethoxazole curcumin

Conditions

Conditions	Yield
With acetic acid In ethanol at 60℃; for 2h;	90%

: 723-46-6
sulfamethoxazole

: 103-71-9
phenyl isocyanate

: N-(5-methylisoxazol-3-yl)-4-(3-phenylureido)benzenesulfonamide

Conditions

Conditions	Yield
In acetonitrile at 20℃; for 11.5h; Reflux;	90%
In N,N-dimethyl-formamide at 90 - 100℃;	1.74 g

: 723-46-6
sulfamethoxazole

: 90-02-8
salicylaldehyde

: 4-[(3-formyl-4-hydroxyphenyl)diazenyl]-N-(5-methylisoxazol-3-yl)benzenesulfonamide

Conditions

Conditions	Yield
Stage #1: sulfamethoxazole With hydrogenchloride; sodium nitrite at 0 - 5℃; Stage #2: salicylaldehyde With sodium hydroxide In water	90%
Stage #1: sulfamethoxazole With hydrogenchloride In water for 0.5h; Stage #2: With sodium nitrite In water at 0 - 5℃; Stage #3: salicylaldehyde With hydrogenchloride; potassium hydroxide In water Cooling with ice;

: 723-46-6
sulfamethoxazole

: 126-81-8
dimedone

: 4‐((5,5‐dimethyl‐3‐oxocyclohex‐1‐en‐1‐yl)amino)‐N‐(5‐methylisoxazol‐3‐yl)benzenesulfonamide

Conditions

Conditions	Yield
With trichloroacetic acid at 140℃; for 0.25h;	90%

: 723-46-6
sulfamethoxazole

: 1600-27-7
mercury(II) diacetate

: Hg(sulfamethoxazolato)2

Conditions

Conditions	Yield
In methanol Hg(II) acetate in methanol added dropwise with stirring; stirred (18 h,room temp.); filtered off; air dried; elem. anal.;	89%

: 723-46-6
sulfamethoxazole

: 5429-22-1
4-(4-methoxybenzylidene)-2-phenyl-5(4H)-oxazolone

: 843640-09-5
C27H22N4O5S

Conditions

Conditions	Yield
Stage #1: sulfamethoxazole; 4-(4-methoxybenzylidene)-2-phenyl-5(4H)-oxazolone at 140℃; for 1h; Stage #2: In acetone for 8h; Reflux;	89%

: 98885-93-9, 115851-80-4, 147556-16-9
curcumin

: 723-46-6
sulfamethoxazole

: 1443768-33-9
3-sulfamethoxazole curcumin

Conditions

Conditions	Yield
In ethanol at 60℃; for 4h;	89%

: 18342-66-0
2,5-dioxopyrrolidin-1-yl methylcarbamate

: 723-46-6
sulfamethoxazole

: N-(5-methylisoxazol-3-yl)-4-(3-methylureido)benzenesulfonamide

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In acetonitrile for 24h;	89%

Sulfamethoxazole Chemical Properties

IUPAC Name: 4-Amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide
Synonyms of Sulfamethoxazole (CAS NO.723-46-6): 3-(p-Aminophenylsulfonamido)-5-methylisoxazole ; 3-(para-Aminophenylsulphonamido)-5-methylisoxazole ; 3-Sulfanilamido-5-methylisoxazole ; 5-Methyl-3-sulfanilamidoisoxazole ; Benzenesulfonamide, 4-amino-N-(5-methyl-3-isoxazolyl)- ; Sulphamethylisoxazole
CAS NO: 723-46-6
Molecular Formula: C₁₀H₁₁N₃O₃S
Molecular Weight: 253.27
Molecular Structure:
EINECS: 211-963-3
H bond acceptors: 6
H bond donors: 3
Freely Rotating Bonds: 2
Polar Surface Area: 75.03 Å²
Index of Refraction: 1.641
Molar Refractivity: 62.45 cm³
Molar Volume: 173.1 cm³
Surface Tension: 70.9 dyne/cm
Density: 1.462 g/cm³
Flash Point: 245.4 °C
Enthalpy of Vaporization: 74.7 kJ/mol
Boiling Point: 482.1 °C at 760 mmHg
Vapour Pressure: 1.87E-09 mmHg at 25°C
Melting point: 166-169°C
Storage temp: 0-6°C
Stability: Stable, but light sensitive. Incompatible with strong oxidizing agents
Appearance: Crystals or white powder
Water solubility: Insoluble in water
Product Categories of Sulfamethoxazole (CAS NO.723-46-6): Antibiotics for Research and Experimental Use;Biochemistry;Sulfonamides (Antibiotics for Research and Experimental Use)

Sulfamethoxazole Uses

Sulfamethoxazole (CAS NO.723-46-6) is a sulfonamide bacteriostatic antibiotic. Sulfamethoxazole is most often used as part of a synergistic combination with trimethoprim in a 5:1 ratio in co-trimoxazole. Besides it is commonly used to treat urinary tract infections and toxoplasmosis. In addition it can still be used as an alternative to amoxicillin-based antibiotics to treat sinusitis.

Sulfamethoxazole Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LDLo	oral	3gm/kg (3000mg/kg)		"Experimental Chemotherapy, Volume II," Schnitzer, R.J., and F. Hawking, eds. Academic Press New York, 1964Vol. 2, Pg. 249, 1964.
mouse	LD50	intraperitoneal	2300mg/kg (2300mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Chemotherapy Vol. 21, Pg. 175, 1973.
mouse	LD50	intravenous	1460mg/kg (1460mg/kg)		"Modern Pharmaceuticals of Japan, V," Tokyo, Japan Pharmaceutical, Medical and Dental Supply Exporters' Assoc., 1975Vol. -, Pg. 105, 1975.
mouse	LD50	oral	2300mg/kg (2300mg/kg)		Chemotherapia. Vol. 8, Pg. 63, 1964.
mouse	LD50	subcutaneous	> 5gm/kg (5000mg/kg)		Chemotherapy Vol. 21, Pg. 175, 1973.
mouse	LD50	unreported	5gm/kg (5000mg/kg)		Chemotherapia. Vol. 6, Pg. 273, 1963.
rat	LD50	intraperitoneal	2690mg/kg (2690mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Chemotherapy Vol. 21, Pg. 175, 1973.
rat	LD50	oral	6200mg/kg (6200mg/kg)		Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971.
rat	LD50	subcutaneous	> 5gm/kg (5000mg/kg)		Chemotherapy Vol. 21, Pg. 175, 1973.
women	TDLo	oral	160mg/kg/10D- (160mg/kg)	ENDOCRINE: HYPOGLYCEMIA	Archives of Internal Medicine. Vol. 143, Pg. 827, 1983.

Sulfamethoxazole Safety Profile

Hazard Codes: Irritant Xi,Xn
Risk Statements: 36/37/38-43-22
R22: Harmful if swallowed.
R43: May cause sensitization by skin contact.
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36/37/39-22
S22: Do not breathe dust.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany: 2
RTECS: WP0700000
Hazard Note: Irritant
HazardClass: IRRITANT

Sulfamethoxazole Specification

Side effects of Sulfamethoxazole (CAS NO.723-46-6):
The most common side effect of Sulfamethoxazole is gastrointestinal upset. Allergies to sulfa-based medications typically cause skin rashes, hives, or trouble breathing or swallowing and warrant immediate discontinuation of the medication and contact with doctor immediately. In addition Sulfamethoxazole/trimethoprim is also known to increase blood concentrations of the drug warfarin and can cause an unexpected increase in clotting time and uncontrolled bleeding. Sulfamethoxazole can also bring adverse effects Neutropenia and thrombocytopenia if a patient is placed on long-term therapy.

Product Name

Sulfamethoxazole

Synthetic route

Sulfamethoxazole Chemical Properties

Sulfamethoxazole Uses

Sulfamethoxazole Toxicity Data With Reference

Sulfamethoxazole Safety Profile

Sulfamethoxazole Specification

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