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Hangzhou Huarong Pharm Co., Ltd.

DMF are all available! Hangzhou Huarong Pharm Co., Ltd. established since 2009 , has been always focusing on supplying products and services to our clients in the field of small molecule drug. Huarong Pharm has built platforms for the research,

Gemfibrozil DMF

Cas:25812-30-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Gemfibrozil Manufacturer/High quality/Best price/In stock

Cas:25812-30-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Appearance White crystalline powder White crystalline powder Identification

High purity Various Specifications gemfibrozil CAS:25812-30-0

Cas:25812-30-0

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Manufacturers

inquiry

Wuhan Fortuna Chemical Co.,Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; ...... Appearance:White Crystalline Powder Storage:-20°C Freezer Package:1kg/fo

High quality Gemfibrozil CAS 25812-30-0 supplied by Chinese manufacturer

Cas:25812-30-0

Min.Order:25 Kilogram

FOB Price: $50.0

Type:Trading Company

inquiry

Hebei yanxi chemical co.,LTD.

Hebei yanxi chemical co. LTD. has expanded a compositive entity from initially only as a small manufacturer. The company dedicated to the development, production and marketing of chemicals. After many years of efforts, we have established stable

Gemfibrozil

Cas:25812-30-0

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Manufacturers

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C

gemfibrozil manufacturer with low price

Cas:25812-30-0

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Hefei TNJ chemical industry co.,ltd

Superiority Service we can provide: 1. Mixed container: We can mix different items in one container. 2. Quality control: Before shipment, we can provide free sample for test. Inspection before shipping. 3. Packing: We can pack according to you

Good quality Gemfibrozil//25812-30-0

Cas:25812-30-0

Min.Order:25 Kilogram

Negotiable

Type:Trading Company

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Gemfibrozil

Cas:25812-30-0

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% Gemfibrozil 25812-30-0 GMP manufacturer

Cas:25812-30-0

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

Gemfibrozil

Cas:25812-30-0

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Gemfibrozil

Cas:25812-30-0

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Sinoway Industrial Co., Ltd.

Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c

Factory Supply Gemfibrozil powder CAS 25812-30-0

Cas:25812-30-0

Min.Order:1 Kilogram

FOB Price: $20.0

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Product number 35693 English Name Gemfibrozil CAS Number 25812-30-0 Purity 98% Molecular formula C1

Gemfibrozil Cas.no 25812-30-0 98%

Cas:25812-30-0

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hubei DiBo chemical co., LTD

Name:gemfibrozil The alias:Gemfibrozil [USAN:INN:BAN]; 2,2-Dimethyl-5-(2,5-dimethylphenoxy)valeriansaeure; CAS NO:25812-30-0 Molecular formula:C15H22O3 Molecular weight:250.3334 Product Quality 12 years of chemical raw materials Mature operati

gemfibrozil/CAS:25812-30-0/Raw material supply

Cas:25812-30-0

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

Gemfibrozil

Cas:25812-30-0

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 25812-30-0 with best quality

Cas:25812-30-0

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W

Gemfibrozil CAS25812-30-0

Cas:25812-30-0

Min.Order:1 Kilogram

FOB Price: $288.0 / 499.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product Name:Gemfibrozil Formula:C15H22O3 Molecular Weight:250.37 CAS No.:25812-30-0 EINECS:247-280-2 Density:1.044 g/cm3 Melting Point:61-63 °C Boiling Point:394.7 °C at 760 mmHg Flash Point:141.6 °C Appearance: white p

Gemfibrozil CAS:25812-30-0

Cas:25812-30-0

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Hubei Langyou International Trading Co., Ltd

Our Adwantage: 1.We have stock so we can delivery quickly at the very day when receive the payment. 2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order. 3.High quality gua

High Purity Powder CAS 25812-30-0 Gemfibrozil Pharmaceutical Intermediate

Cas:25812-30-0

Min.Order:10 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Gemfibrozil 25812-30-0

Cas:25812-30-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

Pharmaceutical CAS:25812-30-0,A lipid regulator.Gemfibrozil

Cas:25812-30-0

Min.Order:1 Kilogram

FOB Price: $24.0 / 28.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Gemfibrozil CAS:25812-30-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates

Gemfibrozil CAS:25812-30-0

Cas:25812-30-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Terui OP New Material Technology Co., Ltd.

We have overseas warehouses in California, New Laredo Mexico, Vancouver Canada, Amsterdam Netherlands, and Melbourne Australia. Overseas warehouses can provide some of the best-selling products. We look forward to the cooperation of local powerful

Chinese suppliers CAS 25812-30-0 Gemfibrozil

Cas:25812-30-0

Min.Order:0 Metric Ton

Negotiable

Type:Trading Company

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Gemfibrozil

Cas:25812-30-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:25812-30-0

Cas:25812-30-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram

High quality Gemfibrozil CAS NO.25812-30-0

Cas:25812-30-0

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

Gemfibrozil

Cas:25812-30-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Appearance:white crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:Common products:Se

gemfibrozil

Cas:25812-30-0

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Taizhou Crene Biotechnology co.ltd

Our company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-

CI-719 Gemfibrozil 25812-30-0

Cas:25812-30-0

Min.Order:5 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

2,2-dimethyl-5-(2,5-dimethylphenoxy)-3-hydroxypentanoic acid β-lactone
169295-45-8

2,2-dimethyl-5-(2,5-dimethylphenoxy)-3-hydroxypentanoic acid β-lactone

gemfibrozil
25812-30-0

gemfibrozil

Conditions
ConditionsYield
With sodium tetrahydroborate In N,N-dimethyl-formamide for 12h; Ambient temperature;90%
1,3-Bis[2.2-dimethyl-5-(2,5-dimethylphenoxy)-pentanoyloxy]-propane
139483-63-9

1,3-Bis[2.2-dimethyl-5-(2,5-dimethylphenoxy)-pentanoyloxy]-propane

gemfibrozil
25812-30-0

gemfibrozil

Conditions
ConditionsYield
With sodium hydroxide In diethyl ether; ethanol; water82%
methyl 5-(2,5-dimethylphenoxy)-2,2-dimethyl-pentanoate

methyl 5-(2,5-dimethylphenoxy)-2,2-dimethyl-pentanoate

gemfibrozil
25812-30-0

gemfibrozil

Conditions
ConditionsYield
With tetrabutylammomium bromide; water; sodium hydroxide at 73 - 75℃; for 3h; Inert atmosphere;77.6%
With sodium hydroxide In dimethyl sulfoxide; toluene for 4h;860 mg
5-(2,5-dimethylphenoxy)-2,2-dimethylpentanal
39938-97-1

5-(2,5-dimethylphenoxy)-2,2-dimethylpentanal

gemfibrozil
25812-30-0

gemfibrozil

Conditions
ConditionsYield
With N-hydroxyphthalimide; oxygen In acetonitrile at 80℃; under 760.051 Torr; for 10h; Schlenk technique;72%
With potassium carbonate In n-heptane; water
carbon monoxide
201230-82-2

carbon monoxide

5-(2,5-dimethylphenoxy)-2-methylpentan-2-ol

5-(2,5-dimethylphenoxy)-2-methylpentan-2-ol

gemfibrozil
25812-30-0

gemfibrozil

Conditions
ConditionsYield
With copper(I) oxide; sulfuric acid at -12 - -8℃; for 1.5h;56%
carbon monoxide
201230-82-2

carbon monoxide

2-methyl-5-(2,5-dimethylphenoxy)-2-pentene
172533-96-9

2-methyl-5-(2,5-dimethylphenoxy)-2-pentene

gemfibrozil
25812-30-0

gemfibrozil

Conditions
ConditionsYield
With copper(I) oxide; sulfuric acid at -12 - -8℃;47%
carbon monoxide
201230-82-2

carbon monoxide

5-(2,5-dimethylphenoxy)-2-methylpentan-2-ol

5-(2,5-dimethylphenoxy)-2-methylpentan-2-ol

A

gemfibrozil
25812-30-0

gemfibrozil

B

2,2-dimethyl-5-(2,5-dimethyl-4-sulfophenoxy)pentanoic acid

2,2-dimethyl-5-(2,5-dimethyl-4-sulfophenoxy)pentanoic acid

Conditions
ConditionsYield
With copper(I) oxide; sulfuric acid at 0 - 5℃; for 4h;A n/a
B 2.0 g
carbon monoxide
201230-82-2

carbon monoxide

2-methyl-5-(2,5-dimethylphenoxy)-2-pentene
172533-96-9

2-methyl-5-(2,5-dimethylphenoxy)-2-pentene

A

gemfibrozil
25812-30-0

gemfibrozil

B

2,2-dimethyl-5-(2,5-dimethyl-4-formylphenoxy)pentanoic acid

2,2-dimethyl-5-(2,5-dimethyl-4-formylphenoxy)pentanoic acid

Conditions
ConditionsYield
With sulfuric acid at -16℃; for 24h;A 3.5 g
B 1.5 g
5-(2,5-dimethylphenoxy)-2-methylpentan-2-ol

5-(2,5-dimethylphenoxy)-2-methylpentan-2-ol

gemfibrozil
25812-30-0

gemfibrozil

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 66.9 percent / potassium bisulfite / 1.) from 50 to 60 deg C, 5 Torr, 5 min, 2.) from 60 to 120 deg C, 20 min
2: 47 percent / 1.) 98percent H2SO4, Cu2O / -12 - -8 °C
View Scheme
Multi-step reaction with 2 steps
1: 66.9 percent / potassium bisulfite / 1.) from 50 to 60 deg C, 5 Torr, 5 min, 2.) from 60 to 120 deg C, 20 min
2: 3.5 g / 98percent H2SO4 / 24 h / -16 °C
View Scheme
2,5-Dimethylphenol
95-87-4

2,5-Dimethylphenol

1-p-xylyl-4-methyl-1.2.3-triazole

1-p-xylyl-4-methyl-1.2.3-triazole

gemfibrozil
25812-30-0

gemfibrozil

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 91 percent / aq. NaOH, tetrabutylammonium hydroxide / 24 h / Heating
2: 90 percent / aq. p-TsOH / ethyl acetate / 60 °C
3: 90 percent / ZnCl2 / ethyl acetate / 30 h / 4 °C
4: 90 percent / NaBH4 / dimethylformamide / 12 h / Ambient temperature
View Scheme
Multi-step reaction with 4 steps
1: 90 percent / aq. NaOH, tetrabutylammonium hydroxide / Heating
2: aq. p-TsOH / ethyl acetate / 0.75 h / 60 °C
3: 90 percent / ZnCl2 / ethyl acetate / 30 h / 4 °C
4: 90 percent / NaBH4 / dimethylformamide / 12 h / Ambient temperature
View Scheme
3-(2,5-Dimethylphenoxy)-propionaldehyde
164917-45-7

3-(2,5-Dimethylphenoxy)-propionaldehyde

gemfibrozil
25812-30-0

gemfibrozil

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 90 percent / ZnCl2 / ethyl acetate / 30 h / 4 °C
2: 90 percent / NaBH4 / dimethylformamide / 12 h / Ambient temperature
View Scheme
3-(2,5-dimethylphenoxy)propanal dimethylacetal

3-(2,5-dimethylphenoxy)propanal dimethylacetal

gemfibrozil
25812-30-0

gemfibrozil

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 90 percent / aq. p-TsOH / ethyl acetate / 60 °C
2: 90 percent / ZnCl2 / ethyl acetate / 30 h / 4 °C
3: 90 percent / NaBH4 / dimethylformamide / 12 h / Ambient temperature
View Scheme
3-(2,5-dimethylphenoxy)propanal diethylacetal
1025804-42-5

3-(2,5-dimethylphenoxy)propanal diethylacetal

gemfibrozil
25812-30-0

gemfibrozil

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: aq. p-TsOH / ethyl acetate / 0.75 h / 60 °C
2: 90 percent / ZnCl2 / ethyl acetate / 30 h / 4 °C
3: 90 percent / NaBH4 / dimethylformamide / 12 h / Ambient temperature
View Scheme
2,5-Dimethylphenol
95-87-4

2,5-Dimethylphenol

1,3-bis(2,2-dimethyl-5-chloropentanoyloxy)-propane
139483-62-8

1,3-bis(2,2-dimethyl-5-chloropentanoyloxy)-propane

butan-1-ol
71-36-3

butan-1-ol

gemfibrozil
25812-30-0

gemfibrozil

Conditions
ConditionsYield
With sodium hydroxide In hexane; water
2,5-Dimethylphenol
95-87-4

2,5-Dimethylphenol

1,3-bis(2,2-dimethyl-5-chloropentanoyloxy)-propane
139483-62-8

1,3-bis(2,2-dimethyl-5-chloropentanoyloxy)-propane

A

propane-1,3-diyl bis(2-methylpropanoate)

propane-1,3-diyl bis(2-methylpropanoate)

B

gemfibrozil
25812-30-0

gemfibrozil

Conditions
ConditionsYield
With sodium hydroxide; sodium iodide In N-methyl-acetamide; water
With sodium hydroxide; sodium iodide; dimethyl sulfoxide In hexane; water; toluene
2,5-Dimethylphenol
95-87-4

2,5-Dimethylphenol

methyl 5-chloro-2,2-dimethylpentanoate
73441-42-6

methyl 5-chloro-2,2-dimethylpentanoate

5-(2,5-Dimethylphenoxy-2,2-dimethylpentanoci Acid

5-(2,5-Dimethylphenoxy-2,2-dimethylpentanoci Acid

gemfibrozil
25812-30-0

gemfibrozil

C23H29NO5
1313480-49-7

C23H29NO5

A

nicotinic acid
59-67-6

nicotinic acid

B

2-Hydroxyethyl nicotinate
3612-80-4

2-Hydroxyethyl nicotinate

C

gemfibrozil
25812-30-0

gemfibrozil

D

2-hydroxyethyl 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoate
1313404-96-4

2-hydroxyethyl 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoate

E

ethylene glycol
107-21-1

ethylene glycol

Conditions
ConditionsYield
With hydrogenchloride at 37℃; pH=7.4; Kinetics; aq. phosphate buffer; Enzymatic reaction;
isobutyl 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoate
149105-26-0

isobutyl 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoate

A

gemfibrozil
25812-30-0

gemfibrozil

B

C30H42O6
1446438-83-0

C30H42O6

C

C22H34O5
1446438-84-1

C22H34O5

Conditions
ConditionsYield
Stage #1: isobutyl 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoate With sodium hydroxide In toluene at 100 - 112℃; for 7h;
Stage #2: With water at 70 - 80℃;
A 127.5 g
B n/a
C n/a
2,2-dimethylpent-4-enoic acid
16386-93-9

2,2-dimethylpent-4-enoic acid

gemfibrozil
25812-30-0

gemfibrozil

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: dibenzoyl peroxide; hydrogen bromide / hexane / 5 h / 0 - 5 °C
2: sulfuric acid / 16 h / 60 - 70 °C
3: potassium carbonate; tetrabutylammomium bromide / toluene / 18 h / 110 °C / Inert atmosphere
4: tetrabutylammomium bromide; water; sodium hydroxide / 3 h / 73 - 75 °C / Inert atmosphere
View Scheme
2,2-dimethyl-5-bromopentanoic acid
82884-95-5

2,2-dimethyl-5-bromopentanoic acid

gemfibrozil
25812-30-0

gemfibrozil

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sulfuric acid / 16 h / 60 - 70 °C
2: potassium carbonate; tetrabutylammomium bromide / toluene / 18 h / 110 °C / Inert atmosphere
3: tetrabutylammomium bromide; water; sodium hydroxide / 3 h / 73 - 75 °C / Inert atmosphere
View Scheme
4-[(E)-2-phenylvinyl]phenyl-5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoate

4-[(E)-2-phenylvinyl]phenyl-5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoate

A

gemfibrozil
25812-30-0

gemfibrozil

B

trans-4-Hydroxystilbene
6554-98-9

trans-4-Hydroxystilbene

Conditions
ConditionsYield
With sodium hydroxide In ethanol
4-methylsalicylaldehyde
698-27-1

4-methylsalicylaldehyde

2,2-dimethyl-5-bromopentanoic acid
82884-95-5

2,2-dimethyl-5-bromopentanoic acid

gemfibrozil
25812-30-0

gemfibrozil

Conditions
ConditionsYield
With potassium carbonate In acetonitrile for 3h; Reflux;
2,5-Dimethylphenol
95-87-4

2,5-Dimethylphenol

gemfibrozil
25812-30-0

gemfibrozil

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: sodium hydroxide / toluene; dimethyl sulfoxide / 2 h / Reflux
1.2: 110 °C
2.1: sodium hydroxide / toluene; dimethyl sulfoxide / 4 h
View Scheme
methyl 5-chloro-2,2-dimethylpentanoate
73441-42-6

methyl 5-chloro-2,2-dimethylpentanoate

gemfibrozil
25812-30-0

gemfibrozil

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: sodium hydroxide / toluene; dimethyl sulfoxide / 2 h / Reflux
1.2: 110 °C
2.1: sodium hydroxide / toluene; dimethyl sulfoxide / 4 h
View Scheme
gemfibrozil
25812-30-0

gemfibrozil

1,4-dimethyl-2-((4-methylpent-4-en-1-yl)oxy)benzene

1,4-dimethyl-2-((4-methylpent-4-en-1-yl)oxy)benzene

Conditions
ConditionsYield
With 9-(2-chlorophenyl)acridine; chloropyridinecobaloxime(III) In dichloromethane; acetonitrile at 25 - 27℃; for 36h; Irradiation; regioselective reaction;99%
N-hydroxyphthalimide
524-38-9

N-hydroxyphthalimide

gemfibrozil
25812-30-0

gemfibrozil

1,3-dioxoisoindolin-2-yl 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoate

1,3-dioxoisoindolin-2-yl 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane98%
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In tetrahydrofuran at 20℃; Inert atmosphere;98%
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃;94%
gemfibrozil
25812-30-0

gemfibrozil

5-(4-iodo-2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid

5-(4-iodo-2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid

Conditions
ConditionsYield
With iodine; oxygen; 9,10-phenanthrenequinone; trifluoroacetic acid In benzene at 25℃; for 1h; Irradiation; regioselective reaction;98%
2,2'-dipyridyldisulphide
2127-03-9

2,2'-dipyridyldisulphide

gemfibrozil
25812-30-0

gemfibrozil

C20H25NO2S

C20H25NO2S

Conditions
ConditionsYield
With triphenylphosphine In acetonitrile for 3h; Reflux;98%
gemfibrozil
25812-30-0

gemfibrozil

2-(3-(2,5-dimethylphenoxy)propyl)-2-methylpropionyl chloride
79791-29-0

2-(3-(2,5-dimethylphenoxy)propyl)-2-methylpropionyl chloride

Conditions
ConditionsYield
With oxalyl dichloride In dichloromethane; N,N-dimethyl-formamide at 0 - 20℃; for 3h;97.5%
With thionyl chloride In dichloromethane at 40℃; for 1h; Inert atmosphere;72.9%
With oxalyl dichloride In dichloromethane at 0 - 20℃; Inert atmosphere;
gemfibrozil
25812-30-0

gemfibrozil

5-(2,5-dimethylphenoxy)-2,2-dimethylpentan-1-ol
39938-64-2

5-(2,5-dimethylphenoxy)-2,2-dimethylpentan-1-ol

Conditions
ConditionsYield
Stage #1: gemfibrozil With borane-THF In tetrahydrofuran at 0 - 20℃; for 17h;
Stage #2: With water In tetrahydrofuran
97%
With borane-THF In tetrahydrofuran at 0 - 20℃; for 17h;97%
With lithium aluminium tetrahydride In tetrahydrofuran at 70℃; for 12h; Cooling with ice;65.3%
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 70℃; for 12h;37%
gemfibrozil
25812-30-0

gemfibrozil

bromopentene
1119-51-3

bromopentene

pent-4-en-1-yl 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoate

pent-4-en-1-yl 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoate

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 80℃; Inert atmosphere;97%
gemfibrozil
25812-30-0

gemfibrozil

imino(methyl)(pyridin-2-yl)-λ6-sulfanone
76456-06-9

imino(methyl)(pyridin-2-yl)-λ6-sulfanone

N-[5-(2,5-dmethylphenoxy)-2,2-dimethylpentanoyl]-S-methyl-S-2-pyridylsulfoximine
1384980-57-7

N-[5-(2,5-dmethylphenoxy)-2,2-dimethylpentanoyl]-S-methyl-S-2-pyridylsulfoximine

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0 - 20℃; for 12h; Inert atmosphere;96%
gemfibrozil
25812-30-0

gemfibrozil

1-t-Butoxycarbonylpiperazine
57260-71-6

1-t-Butoxycarbonylpiperazine

C24H38N2O4

C24H38N2O4

Conditions
ConditionsYield
Stage #1: gemfibrozil With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane for 5.5h; Cooling with ice;
Stage #2: 1-t-Butoxycarbonylpiperazine With triethylamine In dichloromethane for 12h; Cooling with ice;
96%
gemfibrozil
25812-30-0

gemfibrozil

methyl 4-chloro-2-methylenebutanoate

methyl 4-chloro-2-methylenebutanoate

methyl 1-(5-(2,5-dimethylphenoxy)-2,2-dimethylpentyl)cyclopropane-1-carboxylate

methyl 1-(5-(2,5-dimethylphenoxy)-2,2-dimethylpentyl)cyclopropane-1-carboxylate

Conditions
ConditionsYield
With (4s,6s)-2,4,5,6-tetra(9H-carbazol-9-yl)isophthalonitrile; caesium carbonate In N,N-dimethyl-formamide for 20h; Sealed tube; Irradiation;95%
gemfibrozil
25812-30-0

gemfibrozil

methyl iodide
74-88-4

methyl iodide

methyl 5-(2,5-dimethylphenoxy)-2,2-dimethyl-pentanoate

methyl 5-(2,5-dimethylphenoxy)-2,2-dimethyl-pentanoate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃;94%
With potassium carbonate In N,N-dimethyl-formamide at 20℃;85%
With potassium carbonate In N,N-dimethyl-formamide at 20℃;79%
With tetrabutyl ammonium fluoride In tetrahydrofuran at 20℃; for 4h; Inert atmosphere;64.8%
gemfibrozil
25812-30-0

gemfibrozil

5-(4-chloro-2,5-dimethylphenoxy)-2,2-dimethylvaleric acid
1374011-92-3

5-(4-chloro-2,5-dimethylphenoxy)-2,2-dimethylvaleric acid

Conditions
ConditionsYield
With N-chloro-succinimide; dimethyl sulfoxide In chloroform at 25℃; for 12h; Reagent/catalyst; Schlenk technique;93%
With sodium hypochlorite In methanol; water
gemfibrozil
25812-30-0

gemfibrozil

C15H20O3

C15H20O3

Conditions
ConditionsYield
With tert.-butylhydroperoxide; N-acetyl-3-amino-2-methylpropanoic acid; sodium acetate; palladium diacetate In decane at 60℃; for 12h;93%
With tert.-butylhydroperoxide; N-acetyl-β-alanine; sodium acetate; palladium diacetate In water at 20 - 60℃; for 24.0833h; Sealed tube;
gemfibrozil
25812-30-0

gemfibrozil

2-bromoethanol
540-51-2

2-bromoethanol

2-hydroxyethyl 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoate
1313404-96-4

2-hydroxyethyl 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoate

Conditions
ConditionsYield
With potassium carbonate In acetonitrile Reflux;90.54%
gemfibrozil
25812-30-0

gemfibrozil

1-benzotriazolecarboxylic acid chloride
65095-13-8

1-benzotriazolecarboxylic acid chloride

gemfibrozil 1-benzotriazolide
288576-82-9

gemfibrozil 1-benzotriazolide

Conditions
ConditionsYield
With triethylamine In toluene at 20℃; for 2.5h;89.2%
gemfibrozil
25812-30-0

gemfibrozil

4-chlorobenzoylmethyl bromide
536-38-9

4-chlorobenzoylmethyl bromide

2-(4-chlorophenyl)-2-oxoethyl 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoate

2-(4-chlorophenyl)-2-oxoethyl 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoate

Conditions
ConditionsYield
With potassium carbonate In tetrahydrofuran at 20℃; for 12h;89.2%
gemfibrozil
25812-30-0

gemfibrozil

5-(2,5-dimethylphenoxy)-2,2-dimethylpentanamide

5-(2,5-dimethylphenoxy)-2,2-dimethylpentanamide

Conditions
ConditionsYield
Stage #1: gemfibrozil With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane at 0 - 20℃; for 3h;
Stage #2: With ammonia In dichloromethane at 0℃; for 0.5h;
88.6%
Stage #1: gemfibrozil With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane at 20℃; for 3h;
Stage #2: With ammonia In dichloromethane at 0℃; for 0.5h;
88.6%
gemfibrozil
25812-30-0

gemfibrozil

5-(2,5-dimethylphenoxy)-2,2-dimethylpentanal
39938-97-1

5-(2,5-dimethylphenoxy)-2,2-dimethylpentanal

Conditions
ConditionsYield
With sodium hydride; sodium iodide In tetrahydrofuran at 40℃; chemoselective reaction;88%
Multi-step reaction with 2 steps
1: borane-THF / tetrahydrofuran / 17 h / 0 - 20 °C
2: pyridinium chlorochromate / dichloromethane / 16 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: borane-THF / tetrahydrofuran / 17 h / 0 - 20 °C
2: pyridinium chlorochromate / dichloromethane / 16 h / 20 °C
View Scheme
Stage #1: gemfibrozil With 2,6-dimethylpyridine; (1,2-dimethoxyethane)dichloronickel(II); 4,4'-di-tert-butyl-2,2'-bipyridine; zinc; dimethyl dicarbonate In ethyl acetate for 0.25h; Inert atmosphere; Green chemistry;
Stage #2: With diphenylsilane In ethyl acetate at 60℃; for 16h; Inert atmosphere; Green chemistry;
196 mg
gemfibrozil
25812-30-0

gemfibrozil

N-methyl-tetrachlorophthalimide
14737-80-5

N-methyl-tetrachlorophthalimide

4,5,6,7-tetrachloro-1,3-dioxoisoindolin-2-yl 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoate

4,5,6,7-tetrachloro-1,3-dioxoisoindolin-2-yl 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoate

Conditions
ConditionsYield
With dmap; diisopropyl-carbodiimide In dichloromethane at 20℃;88%
gemfibrozil
25812-30-0

gemfibrozil

2-phenyl-acrylic acid methyl ester
1865-29-8

2-phenyl-acrylic acid methyl ester

methyl 7-(2,5-dimethylphenoxy)-4,4-dimethyl-2-phenylheptanoate

methyl 7-(2,5-dimethylphenoxy)-4,4-dimethyl-2-phenylheptanoate

Conditions
ConditionsYield
With titanium(IV) dioxide In acetonitrile for 48h; Inert atmosphere; Irradiation; Cooling;87%
gemfibrozil
25812-30-0

gemfibrozil

ethylenediamine
107-15-3

ethylenediamine

2C15H22O3*C2H8N2

2C15H22O3*C2H8N2

Conditions
ConditionsYield
In water at 20℃; for 2h;86%
methanol
67-56-1

methanol

gemfibrozil
25812-30-0

gemfibrozil

methyl 5-(2,5-dimethylphenoxy)-2,2-dimethyl-pentanoate

methyl 5-(2,5-dimethylphenoxy)-2,2-dimethyl-pentanoate

Conditions
ConditionsYield
With sulfuric acid for 1h; Reflux;86%
With sulfuric acid Reflux;84%
With sulfuric acid at 80℃; for 16h; Inert atmosphere;
With sulfuric acid
gemfibrozil
25812-30-0

gemfibrozil

1-deutero-5-(2,5-dimethylphenoxy)-2,2-dimethylpentanal

1-deutero-5-(2,5-dimethylphenoxy)-2,2-dimethylpentanal

Conditions
ConditionsYield
Stage #1: gemfibrozil With 2,6-dimethylpyridine; (1,2-dimethoxyethane)dichloronickel(II); 4,4'-di-tert-butyl-2,2'-bipyridine; zinc; dimethyl dicarbonate In ethyl acetate for 0.25h; Inert atmosphere; Green chemistry;
Stage #2: With dideuteriodiphenylsilane In ethyl acetate at 60℃; for 16h; Inert atmosphere; Green chemistry;
86%
1,1-Diphenylethylene
530-48-3

1,1-Diphenylethylene

gemfibrozil
25812-30-0

gemfibrozil

benzaldehyde
100-52-7

benzaldehyde

7-(2,5-dimethylphenoxy)-4,4-dimethyl-1,2,2-triphenylheptan-1-ol

7-(2,5-dimethylphenoxy)-4,4-dimethyl-1,2,2-triphenylheptan-1-ol

Conditions
ConditionsYield
With (4s,6s)-2,4,5,6-tetra(9H-carbazol-9-yl)isophthalonitrile; sodium carbonate In dimethyl sulfoxide at 23 - 25℃; for 12h; Inert atmosphere; Schlenk technique; Sealed tube; Irradiation;86%
gemfibrozil
25812-30-0

gemfibrozil

α-bromoacetophenone
70-11-1

α-bromoacetophenone

2-oxo-2-phenylethyl 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoate

2-oxo-2-phenylethyl 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoate

Conditions
ConditionsYield
With potassium carbonate In tetrahydrofuran at 20℃; for 12h;85.2%
gemfibrozil
25812-30-0

gemfibrozil

1-bromo-3-propanol
627-18-9

1-bromo-3-propanol

C18H27BrO3

C18H27BrO3

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 24h; Inert atmosphere;85%
gemfibrozil
25812-30-0

gemfibrozil

2-Bromo-4'-methoxyacetophenone
2632-13-5

2-Bromo-4'-methoxyacetophenone

2-(4-methoxyphenyl)-2-oxoethyl 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoate

2-(4-methoxyphenyl)-2-oxoethyl 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoate

Conditions
ConditionsYield
With potassium carbonate In tetrahydrofuran at 20℃; for 12h;84.2%
gemfibrozil
25812-30-0

gemfibrozil

benzylacrylate
2495-35-4

benzylacrylate

benzyl 7-(2,5-dimethylphenoxy)-4,4-dimethylheptanoate

benzyl 7-(2,5-dimethylphenoxy)-4,4-dimethylheptanoate

Conditions
ConditionsYield
With piperazine; 9-(2-chlorophenyl)acridine; tetrakis(acetonitrile)copper(I)tetrafluoroborate In dichloromethane at 25 - 27℃; for 14h; Irradiation;84%
gemfibrozil
25812-30-0

gemfibrozil

4-(bromoacetyl)toluene
619-41-0

4-(bromoacetyl)toluene

2-oxo-2-(p-tolyl)ethyl 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoate

2-oxo-2-(p-tolyl)ethyl 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoate

Conditions
ConditionsYield
With potassium carbonate In tetrahydrofuran at 20℃; for 12h;83.7%
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