• Name

  TAPS

• EINECS 249-954-1
• CAS No. 29915-38-6
• Article Data4
• CAS DataBase
• Density 1.483 g/cm³
• Solubility H₂O: 1 M at 20 °C, clear, colorless
• Melting Point 230-235 °C (dec.)
• Formula C₇H₁₇NO₆S
• Boiling Point
• Molecular Weight 243.281
• Flash Point 110°C
• Transport Information
• Appearance White/clear crystalline powder
• Safety 22-24/25-36-26
• Risk Codes 36/37/38
• Molecular Structure
• Hazard Symbols Xi
• Synonyms 3-[N-[Tris(hydroxymethyl)methyl]amino]-1-propanesulfonicacid;N-[Tris(hydroxymethyl)methyl]-3-aminopropanesulfonic acid;NSC 610928;TAPS (buffering agent);Tris(hydroxymethyl)methylaminopropanesulfonicacid;TAPS;
• PSA 135.47000
• LogP -0.95870

Synthetic route

1120-71-4

1,3-propanesultone

77-86-1

2-amino-2-hydroxymethyl-1,3-propanediol

29915-38-6

3-{[tris(hydroxymethyl)methyl]amino}propanesulfonic acid

Conditions

Conditions	Yield
In butan-1-ol

29915-38-6

3-{[tris(hydroxymethyl)methyl]amino}propanesulfonic acid

3H3N*3H(1+)*[CrMo6O18(OH)6](3-)

3H3N*3H(1+)*[O3S(CH2)3NH2C(CH2O)3]CrMo6O18(OH)3(3-)

Conditions

Conditions	Yield
In water at 150℃; for 12h;	90%

29915-38-6

3-{[tris(hydroxymethyl)methyl]amino}propanesulfonic acid

78902-01-9

(R)-1-acetamido-2-phenylethane-1-boronic acid

A

C17H25BN2O7S(2-)*2Na(1+)

B

C17H25BN2O7S(2-)*2Na(1+)

Conditions

Conditions	Yield
With deuteriated sodium hydroxide In water-d2 Esterification; Title compound not separated from byproducts;

...Expand

29915-38-6

3-{[tris(hydroxymethyl)methyl]amino}propanesulfonic acid

98-80-6

phenylboronic acid

A

C13H18BNO6S(2-)*2Na(1+)

B

C13H20BNO7S(2-)*2Na(1+)

C

C13H20BNO7S(2-)*2Na(1+)

Conditions

Conditions	Yield
With deuteriated sodium hydroxide In water-d2 Esterification; Title compound not separated from byproducts;

...Expand

erbium(III) chloride hexahydrate

29915-38-6

3-{[tris(hydroxymethyl)methyl]amino}propanesulfonic acid

366804-92-4

[bis[N-tris(hydroxymethyl)methyl]-3-aminopropane sulfonato]diaquoerbium(III) chloride

Conditions

Conditions	Yield
In water Na-compd:lanthanida-salt molar ratio was 2:1, reflux for 1 h; soln. was cooled to room temp., solid was washed with hot EtOH and recrystd. from hot EtOH-H2O (1:1) mixt., dried in vac. for several h, elem. anal.;

neodymium(III) nitrate hexahydrate

29915-38-6

3-{[tris(hydroxymethyl)methyl]amino}propanesulfonic acid

366804-91-3

[bis[N-tris(hydroxymethyl)methyl]-3-aminopropane sulfonato]diaquoneodymium(III) nitrate

Conditions

Conditions	Yield
In water Na-compd:lanthanida-salt molar ratio was 2:1, reflux for 1 h; soln. was cooled to room temp., solid was washed with hot EtOH and recrystd. from hot EtOH-H2O (1:1) mixt., dried in vac. for several h, elem. anal.;

29915-38-6

3-{[tris(hydroxymethyl)methyl]amino}propanesulfonic acid

N-methyltriethylenediamine hydroxide

[C1ted][TAPS]

Conditions

Conditions	Yield
In water

29915-38-6

3-{[tris(hydroxymethyl)methyl]amino}propanesulfonic acid

14518-69-5

tetra-n-butylphosphonium hydroxide

[TBP][TAPS]

Conditions

Conditions	Yield
In water at 20℃;

29915-38-6

3-{[tris(hydroxymethyl)methyl]amino}propanesulfonic acid

75-59-2

tetramethyl ammoniumhydroxide

C7H16NO6S(1-)*C4H12N(1+)

Conditions

Conditions	Yield
In water at 20℃; for 12h;

29915-38-6

3-{[tris(hydroxymethyl)methyl]amino}propanesulfonic acid

77-98-5

tetraethylammonium hydroxide

C7H16NO6S(1-)*C8H20N(1+)

Conditions

Conditions	Yield
In water at 20℃; for 12h;

29915-38-6

3-{[tris(hydroxymethyl)methyl]amino}propanesulfonic acid

2052-49-5

tetra(n-butyl)ammonium hydroxide

113599-08-9

3-(2-Hydroxy-1,1-bis-hydroxymethyl-ethylamino)-propane-1-sulfonatetetrabutyl-ammonium;

Conditions

Conditions	Yield
In water at 20℃; for 12h;

TAPS Specification