Product Name

  • Name

    Thioridazine

  • EINECS 200-044-2
  • CAS No. 50-52-2
  • Article Data12
  • CAS DataBase
  • Density 1.237 g/cm3
  • Solubility 1.113mg/L(22.5 oC)
  • Melting Point 72-74°
  • Formula C21H26N2S2
  • Boiling Point 515.665 °C at 760 mmHg
  • Molecular Weight 370.583
  • Flash Point 265.665 °C
  • Transport Information
  • Appearance
  • Safety 16-36/37-45-61
  • Risk Codes 11-23/24/25-39/23/24/25-52/53
  • Molecular Structure Molecular Structure of 50-52-2 (Thioridazine)
  • Hazard Symbols F,T
  • Synonyms Phenothiazine,10-[2-(1-methyl-2-piperidyl)ethyl]-2-(methylthio)- (6CI,8CI);10-[2-(1-Methyl-2-piperidyl)ethyl]-2-(methylthio)phenothiazine;2-Methylmercapto-10-[2-N-methyl-2-piperidyl)ethyl]phenothiazine;Sonapax;Thioridazine prolongatum;dl-Thioridazine;
  • PSA 57.08000
  • LogP 5.88850

Thioridazine Chemical Properties

Chemical Name: Thioridazine
IUPAC NAME: 10-[2-(1-Methylpiperidin-2-yl)ethyl]-2-methylsulfanylphenothiazine
CAS No.: 50-52-2
EINECS: 200-044-2
Molecular Formula: C21H26N2S2
Molecular Weight: 370.57 g/mol
Density: 1.23 g/cm3 
Flash Point: 265.7 °C
Boiling Point: 515.7 °C at 760 mmHg
Following is the structure of 10-(2-(1-Methyl-2-piperidyl)ethyl)-2-(methylthio)phenothiazine (50-52-2):


Product Categories about 10-(2-(1-Methyl-2-piperidyl)ethyl)-2-(methylthio)phenothiazine (50-52-2) is mainly refer to Thioridazine 
The chemical synonymous of 10-(2-(1-Methyl-2-piperidyl)ethyl)-2-(methylthio)phenothiazine (50-52-2) are Thioridazine;10-((1-Methyl-2-piperidyl)ethyl)-2-(methylthio)-phenothiazin;10-(2-(1-Methyl-2-piperidinyl)ethyl)-2-(methylthio)-10H-phenothiazin;10-(2-(1-Methyl-2-piperidyl)ethyl)-2-(methylthio)phenothiazine;10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine;10h-Phenothiazine, 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-

Thioridazine Toxicity Data With Reference

1.    

sln-dmg-orl 100 mg/L

     IJEBA6    Indian Journal of Experimental Biology. 11 (1973),403.
2.    

orl-cld TDLo:28 mg/kg/2W-I

     AJPSAO    American Journal of Psychiatry. 143 (1985),1176.
3.    

orl-cld TDLo:28 mg/kg/2W-I:BAH

     AJPSAO    American Journal of Psychiatry. 143 (1985),1176.
4.    

orl-wmn TDLo:14,500 mg/kg/15Y-I:EYE

     CMAJAX    Canadian Medical Association Journal. 132 (1985),737.
5.    

orl-hmn LDLo:43 mg/kg

     ARGPAQ    Archives of General Psychiatry. 34 (1977),955.
6.    

orl-chd TDLo:25 mg/kg:CNS,CVS

     AJDCAI    American Journal of Diseases of Children. 130 (1976),507.
7.    

orl-hmn TDLo:24 mg/kg:ANS AACRAT 52,938,73
8.    

orl-rat LD50:995 mg/kg

     TXAPA9    Toxicology and Applied Pharmacology. 18 (1971),185.
9.    

ipr-rat LD50:150 mg/kg

     PCJOAU    Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. 10 (1976),1001.
10.    

scu-rat LD50:640 mg/kg

     MDCHAG    Medicinal Chemistry: A Series of Monographs. 4 (1967),199.
     

 

Thioridazine Consensus Reports

EPA Genetic Toxicology Program.

Thioridazine Safety Profile

Human poison by ingestion. Experimental poison by ingestion, subcutaneous, and intraperitoneal routes. Human systemic effects by ingestion: heart rate change, muscle contraction or spasticity, parasympatholytic, toxic psychosis, visual field and retinal changes. Human reproductive effects. Experimental reproductive effects. Mutation data reported. An antipsychotic and sedative. When heated to decomposition it emits very toxic fumes of NOx and SOx.

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