CBNumber: CB0663775
Chemical Name: 2,4,7-Triamino-6-phenylpteridine
Molecular Formula: C12H11N7
Formula Weight: 253.26
CAS No: 396-01-0
Synonyms:6-PHENYL-PTERIDINE-2,4,7-TRIAMINE;6-PHENYL-2,4,7-PTERIDINETRIAMINE;6-PHENYL-2,4,7-TRIAMINO PTERIDINE;ADEMINE;2,4,7-TRIAMINO-6-PHENYLPTERIDINE;TRIAMTERENE;2,4,7-triamino-6-fenilpteridina;2,4,7-triamino-6-phenyl-pteridin
molecular structure:
mp :316°C
Fp :11 °C
storage temp:2-8°C
2,4,7-Triamino-6-phenylpteridine relates to pharmaceutical preparations with cardiac, particularly anti-arrhythmic activity. These preparations comprise, as an active principle, at least one compound of formula I: ##STR1## where R represents a lipophilic radical. The pharmaceutical compositions may comprise 2,4,7-Triamino-6-phenylpteridine in the presence of other pharmaceutical excipients and adjuvants.
1. | otr-ham:emb 25 mg/L | ENMUDM Environmental Mutagenesis. 8 (Suppl 6)(1986),4. | ||
2. | cyt-ham:lng 2800 µg/L | GMCRDC Gann Monograph on Cancer Research. 27 (1981),95. | ||
3. | orl-wmn TDLo:42 mg/kg/3W-I:SYS | MJAUAJ Medical Journal of Australia. 147 (1987),262. | ||
4. | orl-rat LD50:400 mg/kg | YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. 21 (1979),775. | ||
5. | ipr-rat LD50:200 mg/kg | YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. 21 (1979),775. | ||
6. | orl-mus LD50:285 mg/kg | FRXXBL French Demande Patent Document. (Commissioner of Patents and Trademarks, Washington, DC 20231) #2314719 . | ||
7. | ipr-mus LD50:249 mg/kg | NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),519. | ||
8. | scu-mus LD50:620 mg/kg | NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),519. |
Poison by ingestion and intraperitoneal routes. Moderately toxic by subcutaneous route. Human systemic effects: body temperature increase, hepatitis. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Harmful if swallowed
Do not breathe dust
Wear suitable protective clothing and gloves
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View