Product Name

  • Name

    Trifluoperazine

  • EINECS 204-219-4
  • CAS No. 117-89-5
  • Article Data11
  • CAS DataBase
  • Density 1.239g/cm3
  • Solubility −, NOx, and SOx. Used as an antipsychotic and sedative. See also FLUORIDES.
  • Risk Codes
  • Molecular Structure Molecular Structure of 117-89-5 (Trifluoperazine)
  • Hazard Symbols UN NO.
  • Synonyms Phenothiazine,10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)- (6CI,8CI);2-Trifluoromethyl-10-[3'-(1-methyl-4-piperazinyl)propyl]phenothiazine;Flurazine; NSC 17474; RP 7623; TFP; Trifluoperazin; Trifluoperazine;Trifluoromethylperazine; Trifluoroperazine; Trifluperazine; Triflurin;Triperazine
  • PSA 35.02000
  • LogP 4.88640

Trifluoperazine Chemical Properties

Product Name: Trifluoromethylperazine (CAS NO.117-89-5)


Molecular Formula: C21H24F3N3S
Molecular Weight: 407.5g/mol
Mol File: 117-89-5.mol
Einecs: 204-219-4
Boiling point: 506 °C at 760 mmHg
Flash Point:  259.8 °C 
Density: 1.239 g/cm3
Surface Tension: 40.3 dyne/cm
Enthalpy of Vaporization: 77.58 kJ/mol
Vapour Pressure: 2.32E-10 mmHg at 25°C
XLogP3-AA: 5
H-Bond Donor: 0
H-Bond Acceptor: 6
Product Categories: Organics

Trifluoperazine Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 120mg/kg (120mg/kg)   Neuropharmacology. Vol. 9, Pg. 235, 1970.
mouse LD50 intravenous 29mg/kg (29mg/kg)   Psychopharmacology Service Center, Bulletin. Vol. 2, Pg. 17, 1963.
mouse LD50 oral 1350mg/kg (1350mg/kg)   Psychopharmacology Service Center, Bulletin. Vol. 2, Pg. 17, 1963.

Trifluoperazine Safety Profile

Poison by intraperitoneal route. An experimental teratogen. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of F−, NOx, and SOx. Used as an antipsychotic and sedative. See also FLUORIDES.

Trifluoperazine Specification

 Trifluoromethylperazine ,its CAS NO. is 117-89-5,the synonyms is 10-(3-(4-Methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)-phenothiazin ; 10-(3-(4-Methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)phenothiazine ; 10-(Gamma-(n'-methylpiperazino)propyl)-2-trifluoromethylphenothiazine ; 10-(Gamma-(n'-methylpiperazino)propyl)-2-trifluoromethylphenothiozine ; 10-(Gamma-(N'-Methylpiperazino)propyl)-2-trifluoromethylphenothiozine ; 10-[3-(4-Methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-10H-phenothiazine ; 10-[3-(4-Methylpiperazin-1-yl)-propyl]-2-trifluoromethylphenothiazine ; 10H-Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)- .

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