- Min.Order :0 Metric Ton
- Purity: ≥ 90% by reversed phase HPLC analysis
- Payment Terms : T/T
Keywords
Chondroitinase ABC Reagent diagnostic reagents
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- Application:Chondroitinase AC is useful in many applications, for example: As research reagent (glycosaminoglycan degradation). For the preparation of di- and oligo-saccharides of chondroitin sulfates and the p
- PackAge:stored in vials
- ProductionCapacity:1000|Metric Ton|Day
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- Transportation:Air shipping
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General Information
Synonyms: Chondroitin sulfate lyase, chondroitin sulfate eliminase
Gene Source: Native Flavobacterium heparinum
EC Number: 4.2.2.5
CAS Number: 9047-57-8
MDL Number: MFCD00130796
Catalyzed Reaction: Chondroitinase AC cleaves, via na elimination mechanism, sulfated and non-sulfated polysaccharide chains containing 1-4 linkages between hexosamines and glucuronic acid residues. The reaction yields oligosacchardie products (mainly disaccharides) containing unsaturated uronic acids which can be detected by UV spectroscopy at 232 nm. The enzyme is active on chondroitin sulfates A and C, chondroitin and hyaluronic acid, but is not active on dermatan sulfate (chondroitin sulfate B).
Substrate Specificity: Chondroiting sulfates A and C, chondroitin, hyaluronic acid. (The specific activity with chondroitin sulfate A is approx 1.5 times higher than the specific activity with chondroitin sulfate C.)
Details:
Chondroitinase AC cleaves, via na elimination mechanism, sulfated and non-sulfated polysaccharide chains containing 1-4 linkages between hexosamines and glucuronic acid residues. The reaction yields oligosacchardie products (mainly disaccharides) containing unsaturated uronic acids which can be detected by UV spectroscopy at 232 nm. The enzyme is active on chondroitin sulfates A and C, chondroitin and hyaluronic acid, but is not active on dermatan sulfate (chondroitin sulfate B).
Substrate Specificity: Chondroiting sulfates A and C, chondroitin, hyaluronic acid. (The specific activity with chondroitin sulfate A is approx 1.5 times higher than the specific activity with chondroitin sulfate C.)
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