CasNo.15421-84-8,7-(DIETHYLAMINO)-5-METHYL-S-TRIAZOLO[1,5-A]PYRIMIDINE CAS NO.15421-84-8,(15421-84-8) Suppliers

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Keywords

7-(DIETHYLAMINO)-5-METHYL-S-TRIAZOLO[1,5-A]PYRIMIDINE TRAPIDIL N,N-Diethyl-5-methyl-[1,2,4]triazolo[5,1-b]pyrimidin-7-amine

Quick Details

Appearance:colourless viscous liquid
Application:Synthetic fragrances
PackAge:drum
ProductionCapacity:10000|Metric Ton|Month
Storage:Room temperature
Transportation:By Sea/Air/DHL

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Details:

7-(DIETHYLAMINO)-5-METHYL-S-TRIAZOLO[1,5-A]PYRIMIDINE Basic information

Product Name:	7-(DIETHYLAMINO)-5-METHYL-S-TRIAZOLO[1,5-A]PYRIMIDINE
Synonyms:	TRAPIDIL;7-(DIETHYLAMINO)-5-METHYL-S-TRIAZOLO[1,5-A]PYRIMIDINE;7-Diethylamino-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine;N,N-Diethyl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine;Trapymin;N,N-Diethyl-5-methyl-[1,2,4]triazolo[5,1-b]pyrimidin-7-amine;7-(Diethylamino)-5-methyl-S-triazolo[1,5-a]pyrimidine ,98%;Avantrin
CAS:	15421-84-8
MF:	C10H15N5
MW:	205.26
EINECS:	239-434-2
Product Categories:
Mol File:	15421-84-8.mol

7-(DIETHYLAMINO)-5-METHYL-S-TRIAZOLO[1,5-A]PYRIMIDINE Chemical Properties

Melting point	98-99.4° (Pfeifer); 102-104° from heptane (Tenor)
density	1.20±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,Room Temperature
solubility	H2O: ≥15mg/mL
pka	pKs = 2.79(at 25℃)
form	powder
color	white to tan
CAS DataBase Reference	15421-84-8

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26
WGK Germany	3
Toxicity	LD50 in mice, rats (mg/kg): 115, 76 i.v.; 380, 235 orally; 155, 100 i.p.; 132, 100 s.c. (Fuller)

MSDS Information

7-(DIETHYLAMINO)-5-METHYL-S-TRIAZOLO[1,5-A]PYRIMIDINE Usage And Synthesis

Chemical Properties	White or almost white, crystalline powder
Originator	Rocornal,Mochida,Japan,1978
Uses	Vasodilator;PDGF antagonist
Manufacturing Process	8.4 g of 5-methyl-7-chloro-s-triazolo-(1,5-a)-pyrimidine were suspended in 30 cc of water and 7.3 g of diethylamine added. After 2 hours heating with stirring, the mixture was concentrated under vacuum. The residue was recrystallized from n-heptane. This process yielded 8.1 g of the 5-methyl-7- diethylamino-s-triazolo-(1,5-a)-pyrimidine having a melting point of 103°C to 104°C. The hydrochloride produced in the usual manner had a melting point of 212°C.
Therapeutic Function	Coronary vasodilator
Safety Profile	Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. An experimental teratogen. Other experimental reproductive effects. A coronary vasodilator. When heated to decomposition it emits toxic fumes of NOx. See also MINES.