CasNo.479-92-5,Propyphenazone CAS NO.: 479-92-5,(479-92-5) Suppliers

1 Gram	FOB Price: USD 2.0000

Min.Order :1 Gram
Purity: 99%
Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

Propyphenazone 1,2-Dihydro-4-isopropyl-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one 1,2-dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl-3h-pyrazol-3-on

Quick Details

Appearance:Colorless liquid
Application:Synthetic fragrances
PackAge:drum
ProductionCapacity:10000|Metric Ton|Month
Storage:Room temperature
Transportation:By Sea/Air/DHL

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Details:

Propyphenazone Usage And Synthesis

Description	This uncharacterized alkaloid has been described by Hartsen as occurring in Iso_x0002_pyrum thalictroides L. No chemical or physical characteristics are known.
Chemical Properties	solid
Uses	Analgesic; antipyretic; anti-inflammatory.
Definition	ChEBI: A pyrazolone derivative that is antipyrine substituted at C-4 by an isopropyl group.
Brand name	539 grippe-dragees;Amipylo-n;Balpiren;Baukal;Caffalgina;Camoplex;Cantacin;Cerebrol;Daturmed;Degripol;Dentocaps a;Dim-antos;Dolibral;Dolo-mineuron;Dysmalgin;Ejcopyrin;Epizon;Escomen;Estesina;Fd 8;Febral;Finigripp;Grippocaps;Heaven;Infantex;Influvit;Isopronazon;Kavapyret;Kuronde;Lysadestat;Mamaslu;Milneuron;Myo-europan;Neuramin;Neuridal;Neuro-spondryl;Nodiras;Noric;Otobacid;Pfeil;Reomin;Retamex;Rheumanol;Rhinivict;Sanalgin-p;Saridon neu;Saridone;Sedospin;Servalgin;Sonotryl;Spalt;Spongamed;Stona;Synpyrin;Vivcet;Wauco-sin;Wecontrin.
World Health Organization (WHO)	Propyphenazone, a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, was introduced in 1951 for the treatment of rheumatic disorders. As it is structurally related to aminophenazone it has been associated with severe blood dyscrasias. However, it cannot be transformed into potentially carcinogenic nitrosamines and has therefore been widely used as a replacement drug for aminophenazone. In certain countries, products containing propyphenazone have now been restricted in their indications, whereas in others they are still available, sometimes as over-the-counter preparations. See also WHO comment for aminophenazone.
References	Hartsen., J. Chem. Soc., 511 (1873) Mirande., Compt. rend., 168,316 (1919)