This paper reports the high temperature top-seeded solution growth (TSSG) of large single crystals of Cr3+-doped YAl3(BO3)4 from a K2Mo3O10B2O3 flux cooled at a rate of 2–4 K per day in the temperature range 950–1060°C, using a crystal rotation rate of 4–6 rpm. Optical absorption measureme...

A new series of rare earth iron borates having the general formula RFe3(BO3)4 (R=Y, Nd, Sm, Gd, Dy or Ho) was synthesized. The compounds were isostructural with huntite, CaMg3(CO3)4, like other rare earth double borates, RM3(BO3)4, M=A1 or Ga. Single crystals of Y and Gd compounds were grown by ...

This work investigates the thermal decomposition of huntite, CaMg3(CO3)4, comparing it to that of dolomite. A small amount of the sample (5.0 mg) is used under atmospheres of various CO2 partial pressures.In the CO2 atmosphere, huntite decomposes in two steps CaMg3(CO3)4 → CaCO3·nMgCO3 + (3 − ...

The occurrence of huntite, Mg3Ca(CO3)4, is described from the basal thrust zone of the Oman ophiolite, where it is much more common than has hitherto been realised. Weathering of serpentinite leads to highly magnesian groundwaters, which in turn results in precipitation of magnesian huntite. In ...

A series of amino, amidino, and aminomethyl derivatives of benzene and cyclohexane were investigated for their inhibitory effect on the activation of trypsinogen. In agreement with earlier reports, amidines were generally much more potent than amines. p-Amidinophenylpyruvic acid, a newly synthes...

Seven crystalline organic acid–base adducts derived from 1,4-bis(benzimidazol-2-yl)butane/1,2-bis(2-benzimidazolyl)-1,2-ethanediol and acidic components (picric acid, 2-hydroxy-5-(phenyldiazenyl)benzoic acid, 5-sulfosalicylic acid, oxalic acid, and 1,5-naphthalenedisulfonic acid) were prepared ...

This feature article covers our efforts to develop a new method for radical reactions of aliphatic carboxylic acids via a photoinduced electron transfer-promoted decarboxylation using an organic photoredox system. Stable, inexpensive, and neutral organic molecules, such as phenanthrene and 1,4-d...

Development of ultra-sensitive, high specific and cost-effective nucleic acids (NAs) biosensors is critical for early diagnosis of cancer, genetic diseases and follows up response to treatment. Metal-organic frameworks (MOFs) as sensing materials underwent significant development in recent years...

Acid fracture is a widely applied stimulation technique in carbonate formations; however, it has yet to be fully engineered. A holistic approach was taken in this study to improve the general understating of acid fracture from the field, laboratory, and modeling perspectives. Fully integrating t...

Based on the quantitative structure-activity relationship (QSAR), some novel p-aminobenzoic acid derivatives as promising cholinesterase enzyme inhibitors were designed, synthesized, characterized and evaluated to enhance learning and memory. The in vitro enzyme kinetic study of the synthesized ...

Cupriavidus sp. strain ST-14 isolated from municipal waste-contaminated soil had previously been described to harbour catabolic potential of assimilating 2- and 4-nitrobenzoic acids. Apart from the mononitrobenzoic acids, strain ST-14 was observed to be capable of utilizing various phenylalkanoi...

Using standard operant procedures with rats trained to discriminate the serotonin (5-HT) agonist 1-(-3-trifluoromethylphenyl)piperazine (TFMPP) (0.5 mg/kg) from saline, tests of stimulus generalization and stimulus antagonism were conducted with propranolol, pindolol, and mesulergine. Neither pr...

A new Mannich base series of piperazine linked berberine analogues was furnished in this study to screen the antioxidant and anticancer potential of the resultant analogues. Alkoxy group at a C-9 position of berberine was converted to hydroxyl functionality to enhance the ability of final scaffo...

Few studies have characterized the subjective effects of N-substituted piperazines, but these drugs show potential for abuse in humans, and have often been associated with MDMA (“ecstasy”) in this regard. The aim of the present study was to test the capacity of N-substituted piperazines to ind...

Using a standard two-lever operant procedure with rats trained to discriminate 1-(3-trifluoromethylphenyl)piperazine (TFMPP) (0.5 mg/kg) from saline, tests of stimulus antagonism and stimulus generalization were performed to better understand the stimulus properties of this agent. The agents exa...

Abuse of synthetic drugs is widespread among young people worldwide. In this context, piperazine derived drugs recently appeared in the recreational drug market. Clinical studies and case-reports describe sympathomimetic effects including hypertension, tachycardia, and increased heart rate. Our ...

Piperazine derived drugs emerged on the drug market in the last decade. The aim of this study was to investigate in vitro the potential hepatotoxicity of the designer drugs N-benzylpiperazine (BZP), 1-(3-trifluoromethylphenyl)piperazine (TFMPP), 1-(4-methoxyphenyl)piperazine (MeOPP) and 1-(3,4-m...

RésuméLa 1-benzylpipérazine (BZP) et la 1-(3-trifluorométhylphényl)pipérazine (TFMPP) sont des substances psychoactives apparues en France, sur le marché des produits illicites, au cours de l’année 2006. Ces molécules sont employées dans les milieux festifs pour leurs propriétés sti...

To prove the intake of recently controlled designer drugs, N-benzylpiperazine (BZP) and 1-(3-trifluoromethylphenyl)piperazine (TFMPP), a simple, sensitive and reliable method which allows us to simultaneously detect BZP, TFMPP and their major metabolite in human urine has been established by cou...

Synthetic drugs are among the most commonly abused drugs in the world. This abuse is widespread among young people, especially in the dance club and rave scenes. Over the last several years, piperazine derived drugs have appeared, mainly available via the internet, and sold as ecstasy pills or u...