The vapor pressure of pure 1-methoxy-2-propanol and 2-methoxyethanol, commonly used as co-solvents in inks, paints, coatings, organic/water solutions among many other applications, were measured with a dynamic recirculation apparatus at a pressure range of (15 to 177) kPa. The measurements were ...
Isobaric (vapor + liquid) equilibria of three binary systems (1-methoxy-2-propanol + 2-methoxyethanol), (2-butanone + 2-methoxyethanol) and (water + 2-methoxyethanol), was measured using an apparatus with dynamic recirculation and gas chromatography analysis for both phases. The measurements wer...
Floor lacquerers’ inhalation and total exposure to 1-alkoxy-2-propanols and 1-(2-methoxy-1-methylethoxy)-2-propanol (DPGME) were measured. The total exposure was biomonitored by urinalysis of free unchanged 1-alkoxy-2-propanols and DPGME. The floor lacquerers’ 8-h inhalation exposures to 1-met...
Excess molar enthalpies, at the temperature of 298.15 K and atmospheric pressure, have been measured for the ternary system {x1 2-Methoxy-2-Methylpropane (MTBE) + x2 1-propanol + (1 − x1 − x2) heptane}, over the whole composition range. Also, experimental data of excess molar enthalpy for the in...
Oil derived from fast pyrolysis of biomass (or bio-oil) is a candidate renewable feedstock for producing hydrogen (H2). In this work, the steam reforming of model oxygenates present in the bio-oil aqueous fraction was studied in a fixed-bed reactor. Using Ni/Al2O3 catalyst, the reactions with 2-...
SummaryA hallmark of aging is a decline in metabolic homeostasis, which is attenuated by dietary restriction (DR). However, the interaction of aging and DR with the metabolome is not well understood. We report that DR is a stronger modulator of the rat metabolome than age in plasma and tissues. ...
An improved amperometric sarcosine biosensor was constructed based on covalent immobilization of sarcosine oxidase nanoparticles (SOxNPs) onto gold electrode (AuE). The SOxNPs/AuE was characterized by scanning electron microscopy (SEM), fourier transform infrared (FTIR) spectroscopy and electroc...
In 2009, Sreekumar found that sarcosine, as an effective biomarker, can be used to identify prostate cancer. However, it is difficult to detect sarcosine in urine or plasma because of its low concentration. In this work, we describe a simple strategy for the preparation of sarcosine biosensor ba...
Sarcosine is an amino acid derivative, which is considered as a key metabolite in various metabolic processes. Therefore, simple and sensitive detection methods are needed for further understanding its metabolic role and diagnostic value. In this study, we developed a novel method that meets the...
In order to develop a simple, convenient and economic method to detect and quantify the level of sarcosine in human urine samples, we have selected DNA aptamers for sarcosine through a modified affinity chromatography SELEX (Systematic Evolution of Ligands by Exponential Enrichment), which is ba...
An amperometric sarcosine biosensor was fabricated based on covalent immobilization of sarcosine oxidase (SarOx) onto the nanocomposite of carboxylated multi-walled carbon nanotubes (cMWCNT)/chitosan (CHIT) and copper nanoparticles (CuNPs), electrodeposited on gold (Au) electrode. The SarOx/CHIT...
The aim of this work was to study the fermentative production of the N-methylated amino acid sarcosine by C. glutamicum. Characterization of the imine reductase DpkA from Pseudomonas putida revealed that it catalyses N-methylamination of glyoxylate to sarcosine. Heterologous expression of dpkA i...
Organic electrochemical transistors (OECTs) are successfully used for sensitive and selective detection of sarcosine, which is recognized as a potential non-invasive specific biomarker for prostate cancer. The sensitivity and selectivity of OECT-based sarcosine sensors are significantly improved...
Sarcosine is a recently identified biomarker for prostate cancer. However, the rapid detection methods for sarcosine are relatively lack because of the low concentration and the presence of complicated interfering substances in serum or urine. In this manuscript, hollow nanospheres of Fe3O4 was ...
Sarcosine, a potential biomarker for prostate cancer, can be detected in a solid state enzyme based biosensor using sarcosine oxidase, with particle immobilised reagents. A novel fusion protein of the fluorescent protein, mCherry, sarcosine oxidase (SOx), and the polypeptide R5 (R52-mCherry-SOx-...
The organic sulfur compound 3-mercaptopropionic acid (3-MPA) is an important thiol intermediate in organic sulfur metabolism in natural environments. It is generated during degradation of sulfur-containing amino acids (e.g. methionine) and from demethylation of dimethylsulfoniopropionate (DMSP)....
Inherent biocompatibility and stability of zinc oxide nanoparticles (ZnO-NPs) and their biomedical potentials make them an emerging candidate for drug delivery. The aim of this study was to develop and assess a simple procedure for surface functionalization of ZnO-NPs by 3-mercaptopropionic acid...
About 30% of the patients with epilepsy do not respond to clinically established anticonvulsants, despite having effective concentrations of the antiepileptic drug in plasma. Therefore, new preclinical models of epilepsy are needed to identify more efficacious treatments. We describe here a new ...
Nanostructured titanium dioxide (TiO2) films are commonly employed as surface modifiers on medical and dental metallic implants, presenting promising results related to interactions with living tissues, promoting improvements in the in vivo biocorrosion resistance and increased bioactivity when ...
Rotational spectra of 3-mercaptopropionic acid (3-mpa) were measured from 6 to 18 GHz using chirped pulse and cavity-based Fourier transform microwave (FTMW) spectroscopy. Theoretical calculations using the B3LYP-D3BJ and MP2 methods with the aug-cc-pVTZ basis set show the presence of seven ener...
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