Stearoyl lysophosphatidylcholine (sLPC) has protective effects against several lethal sepsis models, even after induction of sepsis, which is associated with sLPC-mediated inhibition of high mobility group box 1 (HMGB1) release. This study investigated the mechanism by which sLPC inhibits lipopo...

A comparative assessment has been made by transmission electron microscopy of negatively stained specimens, of the micellar, aggregated and crystalline states of palmitoyl, oleoyl and ex ovo L-α-lysophosphatidylcholine present in aqueous suspensions. Micelle formation from dry lysophosphatidylc...

The gastrointestinal tract is increasingly viewed as critical in controlling glucose metabolism, because of its role in secreting multiple glucoregulatory hormones, such as glucagon like peptide-1 (GLP-1). Here we investigate the molecular pathways behind the GLP-1- and insulin-secreting capabil...

The reaction of α-chlorooximes or the isomeric nitrosochlorides with keto-stabilized dimethylsulphonium or triphenylarsonium ylides affords trans-5-acyl-Δ2-isoxazolines (VIIa-m) in good yields. The NOCI adducts of ethylpropenyl ether and ethylstyryl ether on reaction with dimethylsulphonium ph...

Publisher SummaryThis chapter discusses the methods of preparation of arsonium ylides from arsonium salts and their structure, physical properties, chemical reactions, and syntnetic applications. This experiment marked the birth of the Wittig reaction, a novel method for the conversion of carbon...

The synthesis, photo-physical properties and the optical spectroscopy of the starting materials H2TTP (1), [Zn(TTP)](2) and [Zn(TTP)(4,4′-bpy)]0.2(4,4′-bpy.H2O) (3) (TTP = meso-tetratolylporphyrin) are reported. The X-ray molecular structure of the compound shows that this species is a five-co...

The cobalt complexes of: (a) meso-tetratolyl-, (b) 5-(4-carboxyphenyl)-10,15,20-tritolyl, (c) 5,10,15,20-tetra-(4-N-methylpyridyl)tetraiodide, and (d) 5,10,15,20-tetra-(4-pyridyl) porphyrins have been synthesized and characterized by MS, electronic spectra, X-ray diffraction and EPR spectroscopy...

This paper describes the synthesis of the (thiocyanato-N)(meso-tetratolylporphyrinato)zinc(II) chlorobenzene monosolvate complex with the formula [K(2,2,2-crypt)][Zn(TTP)(NCS)]·C6H5Cl (I) using the cryptand-222 to solubilize potassium thiocyanate in chlorobenzene solvent. Complex (I) has been c...

A novel microwave roast process for synthesizing rutile TiO2 having high crystallinity from Panzhihua sulphate titanium slag is developed in the present work. Properties of samples at various stages of reactions including the crystal structure, microstructure and molecular structure, were invest...

The present study investigated the electrochemical degradation of perfluorooctanoic acid (PFOA) by macro-porous titanium suboxide (p-TiSO) anode in the presence of sulfate at pH-neutral condition (pH 6.9 ± 0.3). Based on initial PFOA concentration of 0.1 mmol L−1, current density of 10 mA cm−2 ...

Sperm whale myoglobin was reconstituted with etioheme and the stoichiometric complex formation was confirmed. The proton NMR spectrum of the deoxy myoglobin exhibits an NH signal from the proximal histidine at 78.6 ppm, indicating heme incorporation into the heme pocket to form the FeN(His-F8)...

A series of luminescent praseodymium complexes with different aromatic carboxylic acids have been synthesized and characterized. The photophysical properties of these complexes have been studied with ultraviolet spectra, phosphorescence spectra and fluorescence spectra. Ultraviolet absorption sp...

In the monohydrate Pr(OOC-Ph-NH2)3(H2O) (1), Pr3+ is nine-coordinate with only oxygen atoms coordinating. Two carboxylate groups are bidentate-bridging, four are tridentate-bridging and there is one coordinating water molecule, hence the coordination number is nine. The chains run along [0 1 0]....

Eight- or nine-coordinated trivalent praseodymium complexes derived from para-substituted benzoic acids have been synthesized by the reaction of hydrated Pr(OH)3 with 4-XC6H4CO2H, where X = OMe, H, Cl, NO2, OH, NH2 or F, in dimethylformamide [DMF, (CH3)2NCHO], and eight single crystal X-ray stru...

Solvent-free rare-earth benzoates appear not to be known. As benzoic acid (HOBz) is thermally sufficiently stable (dec 370 °C), the direct oxidation of praseodymium metal with benzoic acid is an excellent route to secure the solvent-free benzoate–benzoic acid adduct Pr(OBz)3(HOBz)2. Light gree...

In this study, a novel phthalonitrile, ethyl 7-(3,4-dicyanophenoxy)coumarin-3-carboxylate (1), was prepared and characterized. The metallophthalocyanines (3–6) were prepared by cyclotetramerization of 1 with the corresponding metal salts {Zn(OAc)2·2H2O, Co(OAc)2·4H2O, Cu(OAc)2, Ni(OAc)2·4H2O...

Capsaicin and dihydrocapsaicin were selected as adulteration markers to authenticate vegetable oils. In this study, a method of immunoaffinity chromatography (IAC) combined with liquid chromatography–tandem mass spectrometry was established for the determination of capsaicin and dihydrocapsaici...

A sensitive and selective reverse-phase high performance liquid chromatographic method with fluorescence detection has been developed for determination of capsaicin (8-methyl-N-vanillyl-(trans)-6-nonenamid) and dihydrocapsaicin (8-methyl-N-vanillylnonanamide) in samples generated in rat small in...

In this work, we showed electrochemical evidences that α-, β-, and γ-cyclodextrins (CDs) form inclusion complex in a solution with capsaicin (CP). The electrochemical behavior of CP was evaluated on carbon paste electrodes modified with CDs. The modified electrodes exhibited a markedly enhanc...

Capsaicin and dihydrocapsaicin are the major active components in pepper spray products, which are widely used for law enforcement and self-protection. The use of pepper sprays, due to their irreversible and other health effects has been under a strong debate. In this study, we compared metaboli...