Lubricating oils are used to decrease wear and friction of movable parts of engines and turbines, being in that way essential for the performance and the increase of that equipment lifespan. The presence of some metals shows the addition of specific additives such as detergents, dispersals and a...

This work reports an ion chromatographic (IC) method for the quantitative determination of inorganic cations (Na+, K+, Mg2+ and Ca2+) in biodiesel samples that were synthesized from different vegetable oils and fat. The proposed method uses water extraction, heating and ultrasound. The limits of...

A series of novel VEGFR-2 inhibitors containing oxime as hinge binding fragment were described. A strategy of pseudo six-membered ring formed through intramolecular hydrogen bond was employed to mimic the planar quinazoline. The oxime group was firstly introduced to interact with hinge region of...

Two single- and a dual-type electrochromic devices (ECDs) based on poly(3-tetradecylthiophene) (PTDT) and poly(3,4-ethylenedioxythiophene) (PEDOT) with lithium salt in PMMA gel-media were prepared. In the single-type ECDs, red PTDT (λmax: 494 nm) and blue PEDOT (λmax: 596 nm) in the reduced st...

A new enzyme-mediated synthesis of 2-vinylinosine, a compound with broad-spectrum RNA antiviral activity, is described. In order to understand the mechanism of action of this compound, we synthesized its monophosphate and investigated the behavior of that compound toward the enzyme, inosine mono...

The new type protecting group, 1-(2-chloroethoxy)ethyl (Cee) group has been employed for the protection of the 2′-OH groups of ribonucleoside residues in the synthesis of oligoribonucleotides by the phosphoramidite approach en a solid support, using the acid-labile 5′-O-dimethaxytrityl (DMTr) ...

The 1-(2-chloroethoxy)ethyl (Cee) group is completely stable under the acidic condition required to remove the 5′-protecting groups in oligonucleotide synthesis, but can be cleaved under the similar conditions to that of the tetrahydropyranyl (Thp) in the region of pH 2–3.

In the National Toxicology Program's toxicity studies, rats were more sensitive than mice to Bis(2-chloroethoxy)methane (CEM) – induced cardiac toxicity following dermal application to male and female F344/N rats and B6C3F1 mice. Thiodiglycolic acid (TDGA) is a major metabolite of CEM in r...

A method of separation for an eleven component mixture comprised of 1-(2-chloroethoxy)-2-[(2-chloroethyl)thio] ethane (4) and its derivatives has been developed using LC–time-of-flight-MS. All analytical figures of merit for compounds 1–11 have been determined. Compound 4 was examined in a sub...

The intramolecular cyclization of substituted 5-(2-chloroethoxy)-1,5-dihydro-2H-pyrrol-2-ones in the presence of lithium diisopropylamide hexamethylphosphoramide in tetrahydrofuran gave tetrahydropyrano[2,3-b]pyrrol-6(2H)-ones and 3,4-dihydro-2H-pyrrolo-[2,1-b][1,3]oxazin-6(8aH)-ones in moderate...

Haloethers are widely used in industry, and the release of these species into the environment is of great concern because of their toxicity and carcinogenicity. The present study deals with the photocatalytic degradation of the haloether, bis(2-chloroethoxy)methane (BCEXM), in the presence of Ti...

Haloethers are widely used in industrial applications, and the release of these toxic and carcinogenic species into the environment is a cause for great concern. In this study, BiVO4 powder is prepared and used as a visible-light catalyst for the photocatalytic degradation of bis(2-chloroethoxy)...

(1S,2S)-1-Amino-2-hydroxy-1,2,3,4-tetrahydronaphthalene, synthesized via a chemoenzymatic approach from naphthalene, has been successfully used as a chiral auxiliary in Reformatsky-type reactions between the corresponding α-bromoacyloxazolidinone and carbonyl compounds.

The reaction of 4-amino-substituted 6-hydrazinyl-1,3,5-triazin-2(1H)-ones with orthoformate proceeds via the Dimroth-type rearrangement to give 5-amino-substituted 1,2,4-triazolo[1,5-a]-1,3,5-triazine-7-ones. IR, NMR and X-ray studies have shown that the only product of the reaction was the [1,5...

Three phenolic derivatives of 1,2-methano-N,N-dipropyl- 1,2,3,4-tetrahydronaphth-2-ylamine 6–8 were synthesized as structural hybrids of the potent 5-HT1A-receptor agonist 8-OH-DPAT 1 and 2 related phenolic phenylcyclopropylamine 4 and 5. The new compounds were assayed for 5-HT1A-receptor affin...

Nearly 800 compounds have been studied for ability to inhibit glycolysis of salivary sediment. These compounds possessed aldehyde, ketone and/or carboxyl groups as a part of the organic structure. The compounds were tested mainly at 1% concentration or half-saturation, in water or in 10% propyle...

In this work, a two-dimensional optical sensing platform for H2O2, glucose, and uric acid (UA) detection is developed, which integrates the advantages of colorimetric and ratiometric fluorescent techniques. ZnFe2O4 magnetic microspheres with an intrinsic peroxidase-like activity are synthesized ...

ObjectiveTo investigate the effects of Tyrphostin Ag 556 on spinal cord ischemia reperfusion injury.

A projectile impacting onto a target is a typical loading case. For the analysis of such cases, knowledge of high strain rate behavior of target materials is essential. Split Hopkinson pressure bar (SHPB) apparatus is generally used for evaluating the high strain rate behavior of materials. In c...

ObjectiveTo investigate the effects of tyrphostin AG 556, a tyrosine kinase inhibitor (TKI) in an experimental model of testicular ischemia–reperfusion (I/R) injury.