The synthesis of SAPO-5 molecular sieves with high silicon contents has been attempted using N,N-dimethylbenzylamine as templating agent. SAPO-5 samples having silicon contents up to 35%, relative to total Si+Al+P, have been achieved. An increase in concentration of the templating agent in the s...

Stepwise substitution of benzylic CH2 protons in ortho-metallated N,N-dimethylbenzylamine (dmba) ligands leads to chiral ortho-metallated N,N,α-trimethylbenzylamine (tmba) and cumyl-N,N-dimethylamine (cuda) ligands. These larger ligands with less or no acidic protons in benzylic position prove ...

The reactions between [Pd(C2,N-dmba)(μ-X)]2 (dmba = N,N-dimethylbenzylamine; X = Cl, Br) and thiourea (tu) in the 1:2 molar ratio at room temperature resulted in the mononuclear compounds [Pd(C2,N-dmba)(Cl)(tu)] (1) and [Pd(C2,N-dmba)(Br)(tu)] (2), which were characterized by elemental analyses...

The synthesis of 2-(diphenylphosphino)-N,N-dimethylbenzylamine, {Ph2P(C6H4CH2NMe2-o)} (1) and its chalcogenide derivatives, {Ph2P(E)(C6H4CH2NMe2-o)} (E = O, 2; S, 3; Se, 4) were described. The reaction of 1 with [Pd(η3-C3H5)Cl]2 affords a cationic complex [{Ph2P(C6H4CH2NMe2-o)}Pd(η3-C3H5)][OTf...

Density, viscosity, refractive index and conductivity of switchable hydrophilicity solvent (SHS) systems (N,N-dimethylbenzylamine (BDMA), water, and carbon dioxide) were measured as a function of molality of BDMAH-bicarbonate salt for the SHS system at temperatures from (283.15–308.15) K. Three...

Palladacyclic complexes derived from N,N-dimethylbenzylamine (dmba) and the benzimidazol-2-ylidene ligands: 1,3-di(cyclohexyl)benzimidazol-2-ylidene (BzImCy), 1,3-di(tert-butyl)benzimidazol-2-ylidene (BzImtBu) and 1,3-di(1-adamantyl)benzimidazol-2-ylidene (BzImAd) were prepared. The yield for (B...

Lipid oxidation is a main source of reactive carbonyls, and these compounds have been shown both to degrade amino acids by carbonyl-amine reactions and to produce important food flavors. However, reactive carbonyls are not the only products of the lipid oxidation pathway. Lipid oxidation also pr...

Biosynthesis of benzylpenicillin in filamentous fungi (e.g. Penicillium chrysogenum - renamed as Penicillium rubens- and Aspergillus nidulans) depends on the addition of CoA-activated forms of phenylacetic acid to isopenicillin N. Phenylacetic acid is also detoxified by means of the homogentisat...

The cysteine protease, falcipain-2 is an important drug target in human malaria parasite Plasmodium falciparum. A new series of 2-(4-(substituted benzoyl)-1,4-diazepan-1-yl)-N-phenylacetamide derivatives 5(a–t) were designed as per pharmacophoric requirements of falcipain-2 inhibitors using lig...

Human sirtuin 2 (SIRT2) plays pivotal roles in multiple biological processes such as cell cycle regulation, autophagy, immune and inflammatory responses. Dysregulation of SIRT2 was considered as a main aspect contributing to several human diseases, including cancer. Development of new potent and...

The solubilities of N-phenylacetamide, 2-methyl-N-phenylacetamide and 4-methyl-N-phenylacetamide in supercritical carbon dioxide were measured using a semi-flow apparatus. The experimental data were taken at 308.2, 318.2 and 328.2 K, and over the pressure range from 10 to 22 MPa. A plug flow flu...

Cyclic voltammetry and controlled-potential (bulk) electrolysis have been employed to investigate the direct electrochemical reduction of 2-chloro-N-methyl-N-phenylacetamide (1a), 2-chloro-N-ethyl-N-phenylacetamide (1b), and 2-chloro-N-phenylacetamide (1c) at carbon and silver cathodes, as well ...

The solid-liquid equilibrium solubility of 2-phenylacetamide in sixteen pure solvents, i.e. methanol, ethanol, n-propanol, isopropanol, n-butanol, isobutanol, n-pentanol, isopentanol, acetone, ethyl acetate, acetonitrile, 2-butanone, 2-pentanone, methyl acetate, ethyl formate and tetrahydrofuran...

Cyclic voltammetry and controlled-potential (bulk) electrolysis have been employed to investigate the direct electrochemical reductions of 2-bromo-N-phenylacetamide (1a) and 2-iodo-N-phenylacetamide (1b) at glassy carbon cathodes in dimethylformamide containing tetramethylammonium tetrafluorobor...

Cyclic voltammograms for the reduction of phenylacetyl chloride and hydrocinnamoyl chloride at mercury cathodes in acetonitrile containing tetraalkylammonium perchlorates exhibit two waves. For each compound the first wave is attributable to cleavage of the carbon-chlorine bond, whereas the seco...

The structure and conformation of phenylacetyl chloride, PhCH2(CO)Cl, has been determined by gas-phase electron diffraction (GED), using results from ab initio calculations (HF and MP2/6-311 + G(d,p)) to obtain restraints on some of the structural parameters. The molecules exist in the gas-phase...

Eight novel piperazine derivatives of metal (Zn, Co, Ni, Cu) phthalocyanine complexes were synthesized from two precursors obtained by the nucleophilic substitution of (N-(2-hydroxyethyl)piperazine)-N′-2-ethane sulfonic acid (HEPES) with both 3-nitro-phthalonitrile and 4-nitro-phthalonitrile. T...

This work deals with the experimental characterization of carbon dioxide (CO2) absorption in an aqueous solution of N-(2-hydroxyethyl)piperazine, by using of digital holographic interferometry. This method enables visualizing the phenomena taking place in the vicinity of the gas–liquid interfac...

[Ag(μ-sac)(μ-ppz)]n, 1 and [Ag(μ-sac)(μ-bheppz)]n, 2 (sac = saccharinate, ppz = piperazine and bheppz = N,N′-bis(2-hydroxyethyl)piperazine) have been synthesized and characterized by elemental analyses, FT-IR, TGA/DTA and X-ray diffraction. Both complexes crystallize in the triclinic P1¯ s...

□ 1,1-Diethoxy-3-(1-naphthoxy)-2-propanol (V), the diethyl acetal of an important aldehyde intermediate in the metabolic N-deal-kylation of propranolol, was prepared from compound X, the product of the reaction of the lithium salt of methyl methylsulfinylmethyl sulfide with 2-(l-naphthoxy)-acet...