There iridium(III) complexes, [Ir(3-MeO-Phtpy)Cl3] (1), [Ir(2-MeO-Phtpy)Cl3] (2) and [Ir(4-MeO-Phtpy)Cl3] (3) with 4′-(3-methoxyphenyl)-2,2′:6′,2″-terpyridine (3-MeO-Phtpy), 4′-(2-methoxyphenyl)-2,2′:6′,2″-terpyridine (2-MeO-Phtpy) and 4′-(4-methoxyphenyl)-2,2′:6′,2″-terpyridine (4-M...

A new DTTA-appended 4-(4-methoxyphenyl)-2,2′-bipyridine ligand has been synthesized for lanthanide cations by Kröhnke method. Its luminescent lanthanide (Eu3+ and Tb3+) water-soluble complexes have been synthesized. The photophysical properties of new chelates were studied. Comparison of the ne...

Carboxymethylcellulose (CMC) acts as a coating material for a magnesium-layered hydroxide-3-(4-methoxyphenyl)propionate (MLH-MPP) nanocomposite via spontaneous self-assembly. The resulting product is called a magnesium-layered hydroxide-3-(4-methoxyphenyl)propionate/carboxymethylcellulose (MLH-M...

The multiformity in polymer structure and conformation design provides a great potential in improving the gene silencing efficiency of siRNA by polymer vectors. In order to provide information on the polymer design for siRNA delivery, the structural contributions of blocked or grafted poly(2-dim...

Radical copolymerizations of 2-(α-d-mannopyranosyloxy)ethyl methacrylate (ManEMA) with 2-dimethylaminoethyl methacrylate (DMAEMA) were carried out in N,N-dimethylformamide (DMF) containing 10 vol% water at 60 °C to yield cationic glycopolymers. The number-average molecular weights (Mns, standa...

Hydrogels with pH/temperature responsiveness and high water uptake have been synthesized by the free radical polymerization of 2-(2-methoxyethoxy)ethyl methacrylate (MEO2MA) with N,N-dimethylaminoethyl methacrylate (DMAEMA) in a low proportion. The amphiphilic character of the biocompatible MEO2...

Block copolymers (BCPs) are interesting precursors to nanoporous films with well-defined and tunable porosities. So far, BCPs with polystyrene (PS) as the majority block are predominantly used, hindering the using of produced nanoporous films at elevated temperatures. Herein, we propose to use B...

Novel deoxycholic acid (DCA) derivatives were stereoselectively synthesised with –OH and –CH2SR moieties at the C-3 position, where R was a substituted aryl [2-aminophenyl (8) or 4-chlorophenyl (9)] or hetaryl [1-methylimidazolyl (5), 1,2,4-triazolyl (6), 5-amino-1,3,4-thiadiazolyl (7), pyridi...

In the reactions with o-aminothiophenol, 4-hydroxy-(3-(imino)acetyl)-5,6,7,8-tetrafluorocoumarins give products of S-substitution at the C-7 atom. 7-Substituted 5,6,8-trifluorocoumarins form benzothiazole as a result of heterocyclic ring opening; 3-ethoxycarbonyl-2-methyl-5,6,7,8-tetrafluorochro...

Methods for synthesis of previously unknown 2-(1-alkyl(aryl)-4-oxo-5,6,7,8-tetrafluoro-1,4-dihydroquinolin-3-yl)glyoxylic acids and their esters from the copper chelate of ethyl pentafluorobenzoylpyruvate were developed. 1-Aryl(alkyl)-3-ethoxalyl-5,6,7,8-tetrafluoro-quinolin-4-ones react with o-...

Treatment of arylmethylideneamines with 5-chloropentanoyl chloride in benzene in the presence of 2,6-lutidine afforded novel trans-4-aryl-3-(3-chloropropyl)azetidin-2-ones in good yields. The latter 3-(3-chloropropyl)-β-lactams were transformed selectively into trans-methyl 1-alkyl-2-arylpiperi...

A selective and sensitive liquid chromatography–tandem mass spectrometry (LC–MS/MS) method was developed for the quantitative determination of 1-(3-chloropropyl)-4-(3-chlorophenyl)piperazine HCl (CCP HCl) a process related impurity in trazodone. The method provided excellent sensitivity at a t...

The biogenic amine octopamine (OA) modulates invertebrate behavior by changing neuronal responses from sensory inputs to motor outputs. However, the OA modulation of visual sensitivity and its possible coupling to diurnal cycles remains unexplored. Here we studied the diurnal variations in the O...

Octopamine, the invertebrate counterpart of adrenaline and noradrenaline, controls and modulates many physiological and behavioral processes in protostomes. It mediates its effects by binding to specific receptors belonging to the superfamily of G-protein coupled receptors. We report the cloning...

Octopamine (OA) is known to play an important role in regulating invertebrate immune responses. In this study, we determined the effects of OA on immunity and physiological regulation in the white shrimp Litopenaeus vannamei. The total haemocyte count (THC), differential haemocyte count (DHC), p...

Temperature has profound effects on the neural function and behaviour of insects. When exposed to low temperature, chill-susceptible insects enter chill coma, a reversible state of neuromuscular paralysis. Despite the popularity of studying the effects of low temperature on insects, we know litt...

The pond snail Lymnaea stagnalis is capable of learning taste aversion by pairing presentations of a sucrose solution and an electric shock and consolidating it into long-term memory (LTM), which is referred to as conditioned taste aversion (CTA). We asked here if the neurotransmitter octopamine...

As the counterparts of the vertebrate adrenergic transmitters, octopamine and tyramine are important physiological regulators in invertebrates. They control and modulate many physiological and behavioral functions in insects. In this study, we reported the pharmacological properties of a new α2...

SummaryEndurance exercise is an effective therapeutic intervention with substantial pro-healthspan effects. Male Drosophila respond to a ramped daily program of exercise by inducing conserved physiological responses similar to those seen in mice and humans. Female flies respond to an exercise st...

Octopamine (OA) is known to play an important role in regulating insect immune responses. In Macrobrachium rosenbergii (18.0 ± 1.7 g), OA at 25.0 and 250.0 pmol/prawn significantly increased THC, semigranular cells (SGCs) and PO activity in hemocytes per 50 μL hemolymph, hyaline cells, granula...