The neuropeptide thyrotropin-releasing hormone (TRH) is recognized to play an important role in controlling energy balance through direct effects on the CNS, although mechanisms explaining the phenomenon are poorly understood. To begin to understand the effects of TRH on CNS control of energy ba...

The cDNA encoding prepro-thyrotropin-releasing hormone (ppTRH) in a teleost, medaka (Oryzias latipes) was isolated and characterized. The medaka ppTRH cDNA codes for 270 amino acid residues including eight TRH progenitor sequences (-Lys/Arg-Arg-Gln-His-Pro-Gly-Lys/Arg-Arg-). In silico analyses o...

This study reports the synthesis of the novel crystalline 4-phenyl-3-((4-phenyl-1H-1,2,3-triazol-1-yl)methyl)-1H-1,2,4-triazole-5(4H)-thione compound in an excellent yield via multi-steps reactions. Probability of the thiol⇔thione tautomerism reaction occurrence via single-proton intramigration ...

p-Hydroxybenzoate 3-hydroxylase from Rhodococcus erythropolis was inactivated by 2,3-butanedione (BD), phenylglyoxal (PGO), and other chemical reagents. p-Hydroxybenzoate and NADH protected the enzyme from inactivation by BD. Judging from the amino acid composition of BD-treated enzyme in the pr...

An asymmetric synthesis of (2S,3S)-3-carboxy-proline starting from (S)-aspartic acid is reported. The methodology also allows the preparation of 5-substituted derivatives.

The N-trifluoroacetyl derivative of the novel β-amino acid (2S,3S,8S,9S)-Adda methyl ester 4 has been prepared from the D-glucose derived oxazoline 7. A key step in the construction of 4 was the generation of the E,E decadienoate system via dissolving metal reduction of vicinal bis-mesylate 15.

α-Bromo β-hydroxy ester 2 was prepared in a preparative scale by a 96 : 4 enantioselective aldol reaction of t-butyl bromoacetate with isobutyraldehyde and converted efficiently to either (2S,3S)- or (2R,3S)-3-hydroxyleucine (7 or 11).

Homochiral (2S,3S)-3-amino-2-phenylthietane (6) was synthesized by the action of potassium O-ethyldithiocarbonate on 1,3-ditosylate (3) or 1,3-diiodide (7) derived from (1S,2S)-2-amino-1-phenyl-1,3-propanediol(1).

The reduction of ethyl 2-methyl-3-oxobutanoate catalyzed by an oxidoreductase from Geotrichum candidum affords corresponding ethyl (2S,3S)-anti-2-methyl-3-hydroxybutanoate with exclusive diastereo- and enantioselectivity.

The title compound of (E)-benzyl 2-((2S,3S,4R)-2,3,4-tris(benzyloxy)hex-5-enylidene)hydrazinecarboxylate was synthesized and characterized by XRD, FT-IR and UV–Vis techniques. The intermolecular hydrogen bonds and π-ring interactions were illustrated by the three-dimensional Hirshfeld surface ...

An intermediate in the conversion of chorismate into 2,3-dihydroxybenzoate has been formed using cell-free extracts of Aerobacter aerogenes. The new compound has been isolated and identified as 5,6-dihydroxycyclohexa-1,3-diene-1-carboxylic acid. The trivial name 2,3-dihydro-2,3-dihydroxybenzoic ...

Highly efficient non-noble materials for water splitting are essential for renewable energy application. Herein, cobalt phosphide nanoparticles with high P/Co ratio are synthesized and display overpotentials of 348 mV (or 343 mV) for oxygen evolution reaction (OER) with surface oxidized active s...

Cobalt phosphide nanoparticles (Co2P) were synthesized via microwave radiation or pyrolysis at 400 °C, and two ionic liquids (IL) were applied as the phosphorus and cobalt dual-source for fabricating Co2P. In the microwave radiation method, tetrabutylphosphonium tetrachlorocobaltate(II) ([P4,4,...

Cobalt phosphide has been extensively studied as non-precious metal-based robust electrocatalyst for hydrogen evolution reaction. Innovation breakthrough is still highly desired to enhance its catalytic efficiency. In this work, through rational engineering strategy, a controlled inner-porous Co...

Phosphorus (P) recovery is of significant importance due to its limited reserves and non-regenerative nature. In this study, we attempted to recover and utilize P from microorganism to obtain metal phosphide/carbon composites. By P-rich cultivation of a model yeast (Candida utilis), a total 4.3 ...

Hierarchical nanostructures have attracted widespread interest owing to their unique properties compared to their bulk counterparts. Thus, they are considered promising electrocatalytic materials. In this work, a novel hierarchical porous nanocomposite of cobalt phosphide [email protected] mixed...

Herein, we examine the application of mesoporous cobalt phosphide (meso-CoP) prepared by a hard-templating method as a novel non-precious electrocatalyst for the oxygen evolution reaction (OER). The obtained meso-CoP exhibits a relatively low overpotential (0.30 V at 10 mA cm−2), a decent Tafel ...

Selective emitters for thermophotovoltaics consisting of intermetallic alloy MoSi2 substrate with plasma-spray coated rare-earth oxides ytterbium oxide Yb2O3, Yb-doped garnet Yb1.5Y1.5Al5O12, and erbium oxide Er2O3 have been successfully tested till 1650 °C. The emitters are fully operable in a...

We present electrical resistivity and a.c. susceptibility data for polycrystalline RSi2 compounds (R ≡ rare earths and yttrium). Measurements have been carried out from room temperature down to 4.2 K. Our data show an antiferromagnetic transition for all compounds, except when R  La, Y, Yb, C...

The magnetic properties of the rare earth disilicides (RSi2) have been re-investigated. We confirm the occurrence of ferromagnetism in PrSi2 and antiferromagnetism in GdSi2, TbSi2, DySi2 and HoSi2. NdSi2 orders at TN = 10 K and ErSi2 orders at Tc = 4.5 K. Crystal field effects are important thro...