Organotins display high biological activity and are toxic to animals and humans. Besides carcinogenic effects, they have been shown to have highly immunotoxic and/or neurotoxic activity; however, the molecular mechanism of their toxicity is not fully understood. The ability of chemicals to inhib...

Diethyl- and diphenyltin derivatives of N-methyl-N-p-bromobenzoylhydroxylamineR2Sn{ON)C6H4Br-p)C(O)C6H4Br-p}2, R=Et, Ph, and N-p-bromophenyl-N-p-bromobenzoylhydroxylamine, R2,Sn{ON(C6H4Br-p)C(O)C6H4Br-p} 2, R = Et, Ph, were made and characterized by IR, Mössbauer and NMR (1H, 13C, 119Sn) spectro...

New organometallic tin(IV) complexes of the empirical formula Sn(NNS)Ph2Cl (NNS = anionic forms of the 2-quinolinecarboxaldehyde Schiff bases of S-methyl- and S-benzyldithiocarbazate) have been prepared and characterized by IR, electronic, 1H NMR and ES mass spectroscopic techniques. The molecul...

The self-assembly reaction of phenylphosphoric acid, sodium ethoxide and diphenyltin dichloride in the ethanol affords a new cage-like macrocycle complex 1, which is a highly centrosymmetric nine-tin nuclear cage containing one water molecule. The X-ray crystal structure shows that the metal ion...

The synthesis and crystal structure of the new tetranuclear diphenyltin(IV) compound [{SnPh2}{SnPh2(OCOMe)}(μ2-OMe)(μ3-O)]2 (1), generated from the reaction of [SnPh2Cl2] and NaOCOMe, are described. Single crystal X-ray diffraction revealed that 1 is a tetranuclear complex with four diphenylti...

Present work deals with the synthesis of Schiff base and its corresponding diorganotin (IV) complex with general formula Ph2SnL [Where Ph = Phenyl, L = 6,6'-((1Z,1′E)-((4-nitro-1,3-phenylene)bis(azanylylidene))bis(methanylylidene))bis(2-methoxyphenol)]. Synthesized Schiff base and organoti...

The binding of the heme enzyme myeloperoxidase to phosphatidylserine epitopes on the surface of non-vital polymorphonuclear leukocytes and other cells at inflammatory sites favours modifications of this phospholipid by myeloperoxidase products. As detected by MALDI-TOF mass spectrometry hypochlo...

Phosphatidylethanolamines (PEs) are abundant lipid constituents of the cellular membrane. The amino group of PEs exhibits high reactivity with hypochlorous acid that is generated under inflammatory conditions in vivo. The analysis of the resulting PE mono- and dichloramines is of significant int...

A novel block copolymer is fabricated by orthogonally coupling two end-functionalized polymers, glucose-capped methoxypoly(ethylene glycol) (mPEG2k-diol) and phenylboronic acid-capped poly(ε-caprolactone) (PBA-PCL), with dual boronate ester and BN/BO dynamic covalent interactions. Due to their ...

Hydrolysis of 4-methoxyphenylacetic acid butyl ester (MPABE) with aqueous potassium hydroxide and catalyzed by tetrabutylammonium bromide in chlorobenzene was investigated in this work. Hydrolysis reaction is greatly enhanced using tetrabutylammonium bromide in the presence of potassium hydroxid...

The present study investigates the alleviation of allelochemical stress induced by benzoic acid (BA), an autotoxic compound, by exogenous indole acetic acid (IAA) in tomato seedlings. The experiment was conducted in hydroponic culture in glass house conditions. BA was applied 0.5 and 1.0 mM conc...

In a multi-step synthesis a series of new basic dyes (4a–4g, 5a–5g and 8a–8g) were prepared starting from 3-(acetoacetamido)pyridine. Whilst coupling of arene-diazonium salts with N-amino-3-(acetoacetamido)pyridinium 2,4-dinitrophenate afforded the N-aminopyridinium cationic dyes (4a–4g) whi...

The X-ray single-crystal structures of N-trimetylsilyl acetamide CH3CONHSiMe3 (1), N-trimethylsilyl trifluoroacetamide CF3CONHSiMe3 (2) and N-trimethylsilyl benzamide PhCONHSiMe3 (3) have been determined. Quantum chemical calculations (B3LYP/6-311+G**, NBO analysis) were performed for gas phase ...

Changes of coumarin content were induced by application of salicylic acid through the root system of 8-week-old Matricaria chamomilla plants in the stage of leaf rosette. Twenty four hours after addition of salicylic acid into culture medium, its accumulation in leaves of chamomile was registere...

A facile capillary electrophoresis (CE) method for the separation of cinnamic acid and its derivatives (3,4-dimethoxycinnamic acid, 4-methoxycinnamic acid, isoferulic acid, sinapic acid, cinnamic acid, ferulic acid, and trans-4-hydroxycinnamic acid) using graphene quantum dots (GQDs) as additive...

In vitro root cultures of Anigozanthos preissii and Wachendorfia thyrsiflora (Haemodoraceae) are suitable biological systems for studying the biosynthesis of phenylphenalenones. Here we report how we used these root cultures to investigate precursor–product relationships between phenylpropanoid...

Background2,4,5-Trimethoxycinnamic acid (2,4,5-TMC) is the major and non-toxic metabolite of α-asarone, which retains hypocholesterolemic and choleretic activities. We compared the activities of 2,4,5-TMC with those of 2,4-dimethoxycinnamic acid (2,4-DMC), 3,4-DMC and 3,5-DMC, to understand the...

The anomalously abundant loss of OCH3 from molecular ions of 2-methoxycinnamic acid is shown to be due to a lowered strength of the ArOCH3+· bond. This is a direct consequence of the raised ionization energy originating from the electronic interaction of the side chain and the substituent.

The kinetic action of tyrosinase on l-tyrosine and l-Dopa as substrates in the presence of cinnamic acid and some of its derivatives has been characterized. Cinnamic acid, 2-hydroxycinnamic, 2,3 and 4-methoxycinnamic acids were seen to be inhibitors of tyrosinase being determined the type of inh...

The Fourier transform infrared (FTIR) and FT-Raman spectra of cis-2-methoxycinnamic acid have been measured in the range 4000–400 and 4000–100 cm−1, respectively. Complete vibrational assignment and analysis of the fundamental modes of the compound were carried out using the observed FTIR and ...