Studies in mice have shown that C-type natriuretic peptide (CNP) is produced by granulosa cells and contributes to ovarian follicle growth and oocyte meiotic arrest until the preovulatory LH surge. In humans, the relationship between intraovarian CNP levels and oocyte meiotic resumption is unkno...

C-peptide level is recognized as an important indicator of diabetes diagnosis. A sensitive and specific double-antibody sandwich enzyme-linked immunosorbent assay for the detection of C-peptide based on double antibody sandwich method was studied in this paper. The rabbit and hen were innunized ...

AimFasting serum C-peptide is a biomarker of insulin production and insulin resistance, but its association with vascular complications in type 2 diabetes mellitus (T2DM) has never been fully elucidated. This study aimed to investigate whether C-peptide is associated with cardiovascular disease ...

Alzheimer's disease (AD) is a neurodegenerative process characterized by the accumulation of extracellular deposits of amyloid β-peptide (Aβ), which induces neuronal death. Monomeric Aβ is not toxic but tends to aggregate into β-sheets that are neurotoxic. Therefore to prevent or delay ...

SummaryThis study was undertaken to observe the type of interaction that exists between polychlorinated biphenyls (Clophen A60) and diethyl phthalate (DEP) on the adrenal and thyroid glands of male and female Wistar rats. Animals were divided into four groups of six animals each, group I male an...

Polychlorinated biphenyls and diethyl phthalate are both lipophilic in nature and are likely to be present in the same environmental compartment or bioaccumalate over a period of time, thus a mixture toxicity study was undertaken to evaluate the type of interaction between polychlorinated biphen...

We have studied the stability of a range of total parenteral nutrition (TPN) mixtures compounded from Lipofundin S and Aminoplex amino acid solutions. Droplet size was studied for 180 days using both light scattering and electrical zone sensing techniques; additionally, the chemical stability wa...

The physical stability of three regimens for total parenteral nutrition (TPN) based on the MCT/LCT (50:50) emulsion Lipofundin MCT/LCT 1 was investigated. A range of different methods was employed for complete characterization of the feeding mixtures (sizing methods: photon correlation spectrosc...

The stability of TPN regimens with high electrolyte load based on the emulsions Lipofundin MCT/LCT and Intralipid was investigated. The regimens were of identical composition containing 66.7 mmol/1 monovalent ions and 6.7 mmol/1 divalent ions (3.4 mmol Ca2+, 3.3 mmol other divalent ions such as ...

Lipostabil, advertised as an injectable product for eliminating fat, has been available for 3 decades in Europe, South America, and South Africa for the treatment of numerous medical conditions. The author outlines what is known about the aesthetic applications of Lipostabil and explores the imp...

BackgroundSubcutaneous injection of Lipostabil Endovena (Nattermann & Cie, Köln, Germany) has been used to treat periorbital fat pads, as well as localized fat deposits in the abdomen, neck, arms, and thighs.

A single-dose trial in mice (1.25 mg/kg SPA-S-753 or 1 mg/kg amphotericin B [AmB] by intravenous route) was performed to study the pharmacokinetics, tissue distribution, and urinary excretion of a new polyene, SPA-S-753 (N-dimethylaminoacetyl-partricin A 2-dimethylaminoethylamide diaspartate), i...

SummaryA series of partricin A amides were synthesized using the active ester method by reaction with several amines on the carboxy group and then with some acids on the mycosamine group of partricin A. Most of the derivatives are more potent antifungals than the known reference standards, inclu...

The purpose of this study was to determine how lomefloxacin (LMF) interacts with human holo-transferrin (HTF) in the presence of two kinds of essential and nonessential amino acids. The investigations were carried out by fluorescence spectroscopy, zeta potential and molecular modeling techniques...

Understanding the effect of glycation on the function of transferrin, the systemic iron transporter, is fundamental to fully grasp the mechanisms leading to the loss of iron homeostasis observed in diabetes mellitus (DM). The spontaneous reaction with protein amino groups is one of the main caus...

Publisher SummaryThis chapter discusses the snake venom toxins that act on nerve and muscle. Although the chapter uses a system of classification, classifying many toxins from snake venoms is difficult. Several factors contribute to the difficulty. The most common of these factors considered are...

The compounds 4-vinylcyclohexene 1,2-monoepoxide (VCM) and 4-Vinylcyclohexene diepoxide (VCD) are the two downstream metabolites of 4-vinylcyclohexene (VCH), an ovotoxic agent in mammals. In addition, VCM and VCD may be found as by-products of VCH oxidation in the environment. Recently, we repor...

4-Vinylcyclohexene diepoxide (VCD) is an industrial occupational health hazard chemical because it induces ovotoxicity in rodents. The current study investigated the impacts of VCD on selected hepatic and renal markers of oxidative stress and inflammation in both sexes of Wistar rats. Thus, male...

The properties of stimulated emission of 1,3,5,7,8-pentamethyl-2,6-diethylpyrromethene-difluoroborate molecules in the film of porous aluminum oxide with were studied. It was established that the fluorescence intensity of the dye increases to a concentration of silver nanoparticles of CAg = 0.42...

Flocculation is a widely used method to treat wastewater effluents. Aluminum oxide particles have been recognized as major parts of effluents of ceramic industries. In this work, the flocculation of aluminum oxide particles with various sizes (0.06-0.6 μm) was analyzed using poly(acrylic acid) ...