The use of alginates as films in food applications has increased in the recent years due to their swelling capacity and overall functionality. This behaviour is a result of their capacity to crosslink with Ca2+ ion. Aiming to fully understand the effect of calcium chloride (CaCl2) crosslinking a...
Alginate is a linear and acidic polysaccharide, composed of (1 → 4) linked β-d-mannuronic acid (ManA) and α-l-guluronic acid (GulA). The ratio of ManA to GulA (M/G) is one of the most important factors for the application of alginate and its derivatives in various areas. In this work, a robus...
ObjectiveThis research aimed to study the anti-inflammatory and immunomodulatory effects of guluronic acid (G2013) on gene expression of TLR4, MyD88, SHIP1, SOCS1, NF-κB, and assessment of the level of IL-1β as a pro-inflammatory cytokine in HEK-Blue hTLR4 cell line.
Alginate oligosaccharides are depolymerization products of alginate by enzymatic degradation or physicochemical treatments. Alginate lyase has received great interests due to its use in oligosaccharide preparation. The substrate specificity of alginate lyase directly determines the type and degr...
BackgroundTo assess the therapeutic efficacy, safety and tolerability of Guluronic acid (G2013) in patients with ankylosing spondylitis (AS) patients.
This review traces the development of silver (Ag) as a die attach bonding material in the microelectronic packaging industry from its’ early days as micron-scale silver flakes to the recent nanoscale Ag paste and other derivatives. Basic materials properties include the composition of Ag pastes...
Lipid peroxidation in silver-treated mice was assayed by measuring the malondialdehyde (MDA) content of liver, kidney and brain tissue. After a single intraperitoneal injection of 20 mg/kg silver lactate, lipid peroxidation was significantly increased in the liver 3, 12 and 48 h after exposure w...
The large-scale fabrication of nanocomposite based biosensors is always a challenge in the technology commercialization from laboratory to industry. In order to address this issue, we have designed a facile chemical method of fabricated nanocomposite ink applied to the screen-printed biosensor c...
Silver nanoparticles (Ag NPs) are used in consumer products and wound dressings due to their antimicrobial properties. However, in addition to toxic effects on microbes, Ag NPs can also induce stress responses as well as cytotoxicity in mammalian cells. We observed that Ag NPs are efficiently in...
The development of smartphone–based biosensors for point-of-care testing (POCT) applications allows realizing “all in one” instruments, with large potential distribution among the general population. With this respect, paper color-based detection performed by reflectance measurement is the mo...
Silver nanoparticles (Ag NPs) are known for their antibacterial properties and are used in a growing number of nano-enabled products, with inevitable concerns for releases to the environment. Nanoparticles may also be antigenic and toxic to the haematopoietic system, but the immunotoxic effect o...
In this paper, visual detection of trace lead ion was established by aptamer and silver staining. The basic strategy was that aminated PS2.M aptamer was immobilized onto slide and formed stable G-quadruplex structure. PbS was generated by adding S2−, and it catalyzed subsequent silver staining r...
BackgroundDepressive episodes and cognitive impairment are major causes of morbidity and dysfunction in individuals suffering from bipolar disorder (BD). Novel treatment approaches that target clinical and cognitive aspects of bipolar depression are needed, and research on pathophysiology sugges...
The present work describes a non invasive lactate sensing in sweat during workout. The sensing system is based on a non-equilibrium potentiometric measure performed using disposable, chemically modified, screen printed carbon electrodes (SPCEs) that can be wetted with sweat during the exercise. ...
Lactate concentration is studied as an indicator of physical performance in sports activities, and is also analyzed in health care applications, as well as in the food and cosmetic industries. This organic acid is routinely determined in different concentration ranges, depending on the type of s...
Powders of l-lysine monohydrochloride and l-glutamic acid hydrochloride were gamma irradiated and the induced free radicals were investigated at room temperature by electron magnetic resonance techniques. The observed species in these compounds were attributed to the H2NCH2CH2CH2CH2ĊHCOOH and HO...
1.1. Rhodospirillum rubrum failed to grow from small inocula in the presence of DL-glutamic acid although washed suspenesions of the organism metabolized both isomers.2.2. In the presence of high concentration of DL-glutamic acid the organism initially failed to divide although cells increased i...
Semiorganic nonlinear optical single crystal l-glutamic acid hydrochloride has been studied by Raman spectroscopy under high pressure conditions. Our results show that this amino acid crystal presents one structural phase transition at about 2.1 GPa and one molecular conformational change around...
The electron paramagnetic resonance spectra of γ-irradiated l-(−) malic acid, N-methyl-dl-valine and l-glutamic acid γ-ethyl ester powders have been investigation at room temperature. Radiation damage centres are attributed to HOOCCH2ĊHCOOH, (CH3)2ĊCH(NHCH3)COOH and C2H5OCOCH2CH2Ċ(NH2)COOH rad...
The electron paramagnetic resonance (EPR) of gamma irradiated powders of dl-alanine ethyl ester hydrochloride, l-theanine and l-glutamic acid dimethyl ester hydrochloride were investigated at room temperature. The observed paramagnetic species were attributed to the CH3ĊHCOOC2H5, –CH2ĊHCOOH and...
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