Eight pregnant rhesus monkeys were injected with 100 μg diethylstilbestrol dipropionate (DESDP) from the 40th day of gestation until term, a long-term treatment. Male (n= 3) and female (n= 5) offspring were obtained. Five other pregnant females were injected with DESDP beginning on the 115th da...
The effects of compounds with the stilbene pharmacophore [diethylstilbestrol (DES), DES derivatives, tetrahydrochrysene (THC), and THC derivatives] were examined for their ability to inhibit thrombin-induced Ca 2 + influx in human platelets. DES derivatives (DES dimethyl ether, DES d...
Protein–surface interaction may determine the success or failure of an implanted device. Not much attention have been paid to the specific surface parametes of hydroxyapatite (OHAp) that modulates and determines the formation and potential activity of the layer of proteins that is first formed ...
Hydroxyapatite (HAp) nanoparticle-armored poly(ε-caprolactone) (PCL) microspheres were fabricated via a “Pickering-type” emulsion solvent evaporation method in the absence of any molecular surfactants. It was clarified that the interaction between carbonyl/carboxylic acid groups of PCL and th...
Single‐phase nanocrystalline biocompatible Zn‐doped A‐type carbonated hydroxyapatite (A‐cHAp) powder has been synthesized via mechanical alloying of a stoichiometric mixture of CaCO3, CaHPO4·2H2O and ZnO powders in open air at room temperature by 10 h of milling. The A‐type carbonation in ...
Diseases exhibiting excessive bone loss are often characterized by an increase in the size and number of osteoclasts in affected areas, suggesting that osteoclast size is associated with increased resorptive activity or efficiency. Because osteoclastic bone resorption depends on proton extrusion...
To provide ceramic electrets with superior biocompatibility and controlled surface energy utilizing long‐distance ionic conduction under a DC electric field, the conduction property of B‐type carbonated apatite (CA) ceramics with various carbonate content was investigated by complex impedance ...
This work is devoted to the preparation of carbonated calcium phosphate apatites. The aim was to produce dense ceramics containing various and precisely controlled amounts of carbonate ions partially substituting either for phosphate (B-type apatites) or for hydroxide ions (A-type apatites). Pow...
Because of the limited observations of published studies, the condition of hydroxyapatite after a long period of intraoral function remains a concern. This clinical report describes the histologic evaluation of a 9 year-old hydroxyapatite specimen retrieved from a human subject. The residual hyd...
An ion-selective electrode with a liquid membrane selective to papaverine has been elaborated. The active membrane component is papaverine-tetraphenylborate a com-pound soluble in chlorobenzene. The calibration curve (E = f(log c)) for papaverine is linear in the range from 1 x 10(-5) to 5 x 10 ...
A flow-injection manifold is proposed for the on-line photochemical derivatization of thioridazine hydrochloride. The phodegradation is carried out in the coil of the injection valve, constituted of a PTFE tubing helically coiled around a UV lamp. Aqueous nitric acid was used as the carrier st...
Nitrogen-doped carbon nanotubes (N-CNTs)/gold composites were synthesized through a simple self-assembly method. The morphology, composition, and optical properties of the resulted composites were investigated by transmission electron microscopy, scanning electron microscopy, X-ray diffraction, ...
Biodegradable microspheres of poly(dl-lactic-co-glycolic acid) (PLGA) containing thioridazine HCl were produced by four emulsion–solvent evaporation methods including an O/W emulsion method, an O/O emulsion method, a W/O/W multiple emulsion method, and a W/O/O/O multiple emulsion method. Gel pe...
Thioridazine is a commonly prescribed phenothiazine drug administered as a racemate and it is believed that its antipsychotic effect is mainly associated with (R)-thioridazine. A method based on high-performance liquid chromatography has been developed for the determination of the enantiomers o...
The crystal structure of ribonuclease Ms*3 + -guanylic acid complex has been determined by molecular replacement methods based on the known structure of ribonuclease T 1 . The pattern of hydrogen-bonds between the enzyme and the guanine base is similar to that discovered by Arni ...
At pH 4.0, the RNase T 1 -2'GMP complex (1) crystallizes isomorphously with the isoenzyme complex (2) (Heinemann, U. and Saenger, W., 1982, Nature 299, 27-31). The X-ray structure of 1 was refined with 1.9 Å data to R = 0.195. Polypeptide folding is similar in 1 and 2. However, the sugar...
Characterization of A 2 B receptors is hampered by the lack of selective pharmacological probes and often relies on their relative affinity to agonists that are selective at other receptor types. This approach is limited because the affinity of A 2 B receptors for putati...
Induced hypotensive anesthesia is very applicable to oral surgery, especially orthognathic surgery, because blood loss in these operations is often severe enough that the patient needs a blood transfusion, and because bleeding during surgery interferes with the accurate performance of the operat...
The changes in the contents of cyclic AMP, cyclic GMP, ATP, ADP, AMP and fructose-2,6-bisphosphate that occur in the mantle tissue of the mussel Mytilus galloprovincialis Lmk were analysed with regard to the annual gametogenic cycle. Throughout 2 years, the lowest contents of AMP, ADP and ATP we...
In the interest of pursuing the synthesis of 2′‐O‐carbamoylmethyl‐modified oligonucleotides from building blocks already containing the modification, we have performed studies on the chemical and enzymatic stability of a 2′‐O‐carbamoylmethyl‐modified dinucleotide. The dinucleotide was su...
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View