A stability‐indicating method of analysis for homatropine methylbromide in pharmaceutical formulations was developed. This method is based on the formation of a picric acid‐quaternary ammonium complex, which is adsorbed on acid‐washed diatomaceous earth in alkaline media followed by on‐colum...
SummaryThe administration of homatropine eye-dropsprecipitated several episodes of delirium in a 69-year-old woman. The unusual susceptibility of this patient to the central anticholinergic effect of homatropine is perhaps related to a preexisting mild cognitive defect possibly related to a chol...
A capillary zone electrophoresis method is described for the simultaneous determination of atropine, homatropine and scopolamine. Successful results were obtained after optimization of the electrophoretic parameters such as buffer composition and pH. The best separation was achieved using a 100 ...
A nonsolvolytic (solid-state) reaction between aspirin and homatropine, yielding acetylhomatropine and free salicylic acid, is reported. A GC assay for homatropine is described. In the presence of excess aspirin, the kinetics are pseudo first order with respect to homatropine. The apparent heat ...
A flow-injection turbidimetric procedure exploiting merging zones is proposed for determining homatropine methylbromide (HMB) in pharmaceutical preparations. The determination is based on the precipitation reaction of homatropine methylbromide with silicotungstic acid in acidic medium to form a ...
PurposeTo assess the effect of homatropine eye drops on pain after photorefractive keratectomy (PRK).
In this work, we studied the combination of chemometric methods with chromatographic separations as a strategy applied to the analysis of enantiomers when complete enantioseparation is difficult or requires long analysis times and, in addition, the target signals have interference from the matri...
Homatropine is a tertiary amine antimuscarinic drug with pharmacological effects similar to atropine. It is normally used as the hydrobromide (also a tertiary amine) to produce mydriasis (pupil dilatation) and cycloplegia (paralysis of the ciliary muscle), thereby permitting examination of the e...
PurposeTo compare cycloplegic efficacy of homatropine and atropine in pediatric refractions and derive a regression formula to calculate refraction findings for both agents.
Photolytic transformation of the propellants 2,4-dinitrotoluene (2,4-DNT) and 2,6-dinitrotoluene (2,6-DNT) produces 2,4-dinitrobenzyl alcohol (2,4-DNBOH), 2,6-dinitrobenzyl alcohol (2,6-DNBOH), 2,4-dinitrobenzaldehyde (2,4-DNBCHO), 2,6-dinitrobenzaldehyde (2,6-DNCHO), 2,4-dinitrobenzoic acid (2,...
Air plasma sprayed (APS) 8 wt%-yttria stabilized zirconia (8YSZ) with metastable tetragonal prime phase (t′) has been widely applied as thermal barrier coatings (TBCs) for gas turbine blades because of its outstanding mechanical properties at high temperatures. In the present research, a carefu...
Yttria Stabilized Zirconia ceramics with well-controlled porosity, pore size and shape were prepared using well-calibrated poly-methyl-methacrylate (PMMA) micro-beads (MB) as a pore-forming agent. The microstructure was observed by Scanning Electron Microscopy. Impedance spectroscopy was used to...
Transient and steady state electrotransport and diffusion of ions being produced and annihilated by internal reactions are discussed and exemplified for Yttria Stabilized Zirconia (YSZ). These phenomena are important for understanding flash sintering. They will also play a role in solid oxide fu...
For the Fundamental studies on the phase stability of YSZ, we tried to approach the detailed influences of practical conditions through various hypotheses. The phase stability of cubic and tetragonal yttria-stabilized zirconia (YSZ) was studied in the specific electrochemical conditions of curre...
Structural variations and phase stability in 3 mol% yttria stabilized tetragonal zirconia (3Y-TZP) subjected to long-term aging at room temperature and thermal treatments in air were investigated by Raman and X-ray photoelectron spectroscopies, and compared with previous cases obtained by hydrot...
The ionic conductivity of flash-sintered, polycrystalline 8 mol% yttria stabilized zirconia (8YSZ) was enhanced compared with that of conventionally-sintered specimens. Flash sintering was carried out at a furnace temperature of 850 °C with an electric field of 100 V cm–1 to initiate flash. Th...
In this study, we successfully fabricated an yttria-stabilized zirconia (YSZ) aerogel using the sol-gel method and CO2 supercritical drying. We confirmed the successful thermal insulation function as a thermal barrier coating (TBC) on a high-temperature gas turbine surface. In order to evaluate ...
An array of cross-point memristive devices has been implemented on the basis of yttria-stabilized zirconia thin film for applications in prototypes of spiking neural networks. The resistive switching phenomena and the plasticity nature of such memristive devices are studied. Reproducible bipolar...
Thermal Barrier Coatings (TBCs) play a significant role in improving the efficiency of gas turbines by increasing their operating temperatures. The TBCs in advanced turbine engines are prone to silicate particles attack while operating at high temperatures. The silicate particles impinge on the ...
Monolithic, structurally stable zirconia (ZrO2) aerogels can be used in high temperature applications and as medical implants. The macroscopic properties of these solids can be fine-tuned by the appropriate thermal treatment of the amorphous aerogels. Herein, we investigate the thermally induced...
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