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Jinan Finer Chemical Co., Ltd

Product description: Product name Ethyl chloroacetate CAS number 105-39-5 Assay ≥99.5% Appearance Colorless transparent liquid Capacity 500mt/year Application Pharmaceuticals

Ethyl chloroacetate

Cas:105-39-5

Min.Order:100 Gram

FOB Price: $12.0

Type:Lab/Research institutions

inquiry

Suzhou Sinosun Imp.&Exp. Corporation

Chroma(Pt-Co):10Max; Moisture:0.2%Max; Acidity:0.2%Max; Ethyl Dichloroacetate:0.2%Max;Appearance:colorless Liquid

Ethyl chloracetate

Cas:105-39-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

QINGDAO ON-BILLION INDUSTRAIL CO.,LTD

Ethyl chloroacetate is an important intermediate in the synthesis of pharmaceuticals, pesticides and perfumes, and it also be used as industrial solvents. 1. Colorless liquid. 2. The mature Technical support an professional logistic support 3

Ethyl chloracetate

Cas:105-39-5

Min.Order:0 Metric Ton

Negotiable

Type:Trading Company

inquiry

Pure Chemistry Scientific Inc.

Ethyl chloroacetate Application:810753

Ethyl chloroacetate

Cas:105-39-5

Min.Order:1 Gram

FOB Price: $500.0

Type:Trading Company

inquiry

Synthetic route

ethanol
64-17-5

ethanol

chloroacetic acid
79-11-8

chloroacetic acid

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

Conditions
ConditionsYield
With Candida antarctica lipase B at 20℃; for 36h; Enzymatic reaction;97%
at 105℃; for 3h; Temperature; Molecular sieve;97.4%
F-4SK (H form) In tetrachloromethane at 80℃; for 5h;95%
chloroacetic acid
79-11-8

chloroacetic acid

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

Conditions
ConditionsYield
With thionyl chloride In ethanol; dichloromethane for 0.583333h; Cooling with ice;83%
glycine ethyl ester hydrochloride
623-33-6

glycine ethyl ester hydrochloride

chloroacetyl chloride
79-04-9

chloroacetyl chloride

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

Conditions
ConditionsYield
With sodium hydrogencarbonate In water; toluene at 20℃; for 13h; Cooling with ice;80%
diazoacetic acid ethyl ester
623-73-4

diazoacetic acid ethyl ester

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

Conditions
ConditionsYield
With tertiary butyl chloride; [HB(3,5-(CF3)2Pz)3]Ag(THF)73%
With hydrogenchloride
With hydrogenchloride; diethyl ether
diethyl sulphite
623-81-4

diethyl sulphite

chloroacetic acid
79-11-8

chloroacetic acid

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

Conditions
ConditionsYield
sulfuric acid In ethanol Heating;66%
ethyl acetoacetate
141-97-9

ethyl acetoacetate

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

Conditions
ConditionsYield
With potassium bromate; hydrogenchloride In N,N-dimethyl-formamide at 20℃; for 12h;63%
diazoacetic acid ethyl ester
623-73-4

diazoacetic acid ethyl ester

A

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

B

but-2-enedioic acid diethyl ester
1520-50-9

but-2-enedioic acid diethyl ester

Conditions
ConditionsYield
With tertiary butyl chloride; bis(μ2-2,2,2',2'-tetramethyl-1,3-benzene-di(propanoato-O,O'))rhodium-bismuth at 39.84℃; for 2h; Inert atmosphere;A 46%
B n/a
diazoacetic acid ethyl ester
623-73-4

diazoacetic acid ethyl ester

phenylacetonitrile
140-29-4

phenylacetonitrile

A

2-benzyl-5-ethoxy-1,3-oxazole
74185-57-2

2-benzyl-5-ethoxy-1,3-oxazole

B

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

Conditions
ConditionsYield
aluminium trichloride In neat (no solvent) at 25℃;A 31%
B n/a
4-chloro-5-methyl-isoxazole
7064-36-0

4-chloro-5-methyl-isoxazole

ethanol
64-17-5

ethanol

A

ethyl acetate
141-78-6

ethyl acetate

B

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

Conditions
ConditionsYield
With pyridine for 5h; Heating;A n/a
B 25%
diazoacetic acid ethyl ester
623-73-4

diazoacetic acid ethyl ester

tertiary butyl chloride
507-20-0

tertiary butyl chloride

A

2-chloro-3,3-dimethyl-butyric acid ethyl ester
98551-46-3

2-chloro-3,3-dimethyl-butyric acid ethyl ester

B

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

Conditions
ConditionsYield
Photolysis;
Irradiation.mit UV-Licht;
diazoacetic acid ethyl ester
623-73-4

diazoacetic acid ethyl ester

A

bis-(ethoxycarbonyl-chloro-chloromercurio-methyl)-mercury
26697-96-1

bis-(ethoxycarbonyl-chloro-chloromercurio-methyl)-mercury

B

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

Conditions
ConditionsYield
With mercury dichloride at 0℃;
methanol
67-56-1

methanol

(E)-1,2-dichloro-1-ethoxy-ethene
42345-82-4

(E)-1,2-dichloro-1-ethoxy-ethene

A

methyl chloroacetate
96-34-4

methyl chloroacetate

B

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

phenyl chloroacetate
620-73-5

phenyl chloroacetate

ethanol
64-17-5

ethanol

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

phenyl chloroacetate
620-73-5

phenyl chloroacetate

sodium ethanolate
141-52-6

sodium ethanolate

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

tetrachloromethane
56-23-5

tetrachloromethane

N-chloro-succinimide
128-09-6

N-chloro-succinimide

ketene diethyl acetal
2678-54-8

ketene diethyl acetal

A

ethene
74-85-1

ethene

B

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

diethyl ether
60-29-7

diethyl ether

chloro-acetyl iodide
191340-22-4

chloro-acetyl iodide

A

ethyl iodide
75-03-6

ethyl iodide

B

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

Conditions
ConditionsYield
at 25℃;
at 25℃; bei mehrtaegiger Einw. unter Lichtausschuss; reagiert analog mit Methylbutylaether;
diethyl ether
60-29-7

diethyl ether

chloro-acetyl iodide
191340-22-4

chloro-acetyl iodide

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

Conditions
ConditionsYield
at 25℃; unter Ausschluss von Licht;
ethanol
64-17-5

ethanol

1-ethoxy-2,2-dichloro-ethanol
80944-05-4

1-ethoxy-2,2-dichloro-ethanol

potassium cyanide
151-50-8

potassium cyanide

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

Conditions
ConditionsYield
at 20℃;
(E)-1,2-dichloro-1-ethoxy-ethene
42345-82-4

(E)-1,2-dichloro-1-ethoxy-ethene

ethanol
64-17-5

ethanol

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

Conditions
ConditionsYield
zweckmaessig in Gegenwart von Katalysatoren;
ethanol
64-17-5

ethanol

N-acetyl-2-chloroacetamide
17368-73-9

N-acetyl-2-chloroacetamide

A

ethyl acetate
141-78-6

ethyl acetate

B

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

Conditions
ConditionsYield
Product distribution; im Verhaeltnis 99:1;
ethanol
64-17-5

ethanol

chloroacetyl-propionyl-amine
15322-68-6

chloroacetyl-propionyl-amine

A

Ethyl propionate
105-37-3

Ethyl propionate

B

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

ethanol
64-17-5

ethanol

dichlorodiacetamide
4960-82-1

dichlorodiacetamide

A

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

B

Chloroacetamide
79-07-2

Chloroacetamide

ethanol
64-17-5

ethanol

N-(2-chloroethanoyl)benzamide
7218-27-1

N-(2-chloroethanoyl)benzamide

A

benzoic acid ethyl ester
93-89-0

benzoic acid ethyl ester

B

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

ethanol
64-17-5

ethanol

3-(2-amino-4-methyl-anilino)-2-chloro-crotonic acid ethyl ester
79628-75-4

3-(2-amino-4-methyl-anilino)-2-chloro-crotonic acid ethyl ester

A

2,5-dimethylbenzimidazole
1792-41-2

2,5-dimethylbenzimidazole

B

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

(E)-1,2-dichloro-1-ethoxy-ethene
42345-82-4

(E)-1,2-dichloro-1-ethoxy-ethene

i-Amyl alcohol
123-51-3

i-Amyl alcohol

A

3-methylbutyl chloroacetate
5326-92-1

3-methylbutyl chloroacetate

B

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

(E)-1,2-dichloro-1-ethoxy-ethene
42345-82-4

(E)-1,2-dichloro-1-ethoxy-ethene

n-heptan1ol
111-70-6

n-heptan1ol

A

heptyl 2-chloroacetate
34589-22-5

heptyl 2-chloroacetate

B

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

1-ethoxy-2,2-dichloro-ethanol
80944-05-4

1-ethoxy-2,2-dichloro-ethanol

potassium cyanide
151-50-8

potassium cyanide

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

Conditions
ConditionsYield
With ethanol at 20℃;
(E)-1,2-dichloro-1-ethoxy-ethene
42345-82-4

(E)-1,2-dichloro-1-ethoxy-ethene

succinic acid
110-15-6

succinic acid

A

succinic acid anhydride
108-30-5

succinic acid anhydride

B

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

(E)-1,2-dichloro-1-ethoxy-ethene
42345-82-4

(E)-1,2-dichloro-1-ethoxy-ethene

menthol
89-78-1

menthol

A

2-isopropyl-5-methylcyclohexyl chloroethanoate
106916-72-7

2-isopropyl-5-methylcyclohexyl chloroethanoate

B

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

(E)-1,2-dichloro-1-ethoxy-ethene
42345-82-4

(E)-1,2-dichloro-1-ethoxy-ethene

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

Conditions
ConditionsYield
With alcohols
With mono-basic organic acids
With oxalic acid
3,4-dichlorophenol
95-77-2

3,4-dichlorophenol

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

ethyl 2-(3,4-dichlorophenoxy)acetate
62855-72-5

ethyl 2-(3,4-dichlorophenoxy)acetate

Conditions
ConditionsYield
With potassium carbonate In acetone at 80℃; for 18h;100%
With ethanol; sodium ethanolate
chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

formic acid ethyl ester
109-94-4

formic acid ethyl ester

ethyl 2-chloro-3-oxopropanoate
33142-21-1

ethyl 2-chloro-3-oxopropanoate

Conditions
ConditionsYield
With sodium ethanolate In tert-butyl methyl ether at 0 - 20℃; Inert atmosphere; Large scale;100%
With sodium ethanolate In tert-butyl methyl ether at 0 - 20℃; Inert atmosphere; Large scale;100%
With potassium tert-butylate In tetrahydrofuran at 0 - 20℃; for 16h; Inert atmosphere;95%
chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

acetic acid ethylester sulfonic acid
89124-45-8

acetic acid ethylester sulfonic acid

Conditions
ConditionsYield
With sodium sulfate In ethanol; water100%
With potassium sulfite; ethanol
diphenyl diselenide
1666-13-3

diphenyl diselenide

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

ethyl 2-(phenylselanyl)acetate
51364-94-4

ethyl 2-(phenylselanyl)acetate

Conditions
ConditionsYield
Stage #1: diphenyl diselenide With sodium tetrahydroborate In ethanol at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: chloroacetic acid ethyl ester In ethanol for 1h; Inert atmosphere;
100%
Stage #1: diphenyl diselenide With sodium tetrahydroborate; ethanol at 0 - 25℃; for 1h;
Stage #2: chloroacetic acid ethyl ester at 25℃; for 2h;
98%
Stage #1: diphenyl diselenide With sodium tetrahydroborate In ethanol for 0.166667h;
Stage #2: chloroacetic acid ethyl ester In ethanol at 50 - 55℃; for 0.75h;
94%
chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

E-3-m-hydroxystyrylpyridine
85666-09-7

E-3-m-hydroxystyrylpyridine

1-Ethoxycarbonylmethyl-4-[(E)-2-(3-hydroxy-phenyl)-vinyl]-pyridinium; chloride
79131-36-5

1-Ethoxycarbonylmethyl-4-[(E)-2-(3-hydroxy-phenyl)-vinyl]-pyridinium; chloride

Conditions
ConditionsYield
In ethanol for 10h; Heating;100%
chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

1-<2,6-bis(benzyloxy)-4-hydroxyphenyl>-3-<3-(benzyloxy)-4-methoxyphenyl>propane
76799-30-9

1-<2,6-bis(benzyloxy)-4-hydroxyphenyl>-3-<3-(benzyloxy)-4-methoxyphenyl>propane

1-<2,6-bis(benzyloxy)-4-(carbethoxymethoxy)phenyl>-3-(3-hydroxy-4-methoxyphenyl)propane
76820-12-7

1-<2,6-bis(benzyloxy)-4-(carbethoxymethoxy)phenyl>-3-(3-hydroxy-4-methoxyphenyl)propane

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 40℃; for 22h;100%
chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

2,3',6-tris(benzyloxy)-4-hydroxy-4'-methoxydihydrochalcone
63240-52-8

2,3',6-tris(benzyloxy)-4-hydroxy-4'-methoxydihydrochalcone

2,3',6-tris(benzyloxy)-4-(carbethoxymethoxy)-4'-methoxydihydrochalcone
76799-27-4

2,3',6-tris(benzyloxy)-4-(carbethoxymethoxy)-4'-methoxydihydrochalcone

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 40 - 65℃; for 19h;100%
chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

ethyl 2-(4-bromo-2-chlorophenoxy)acetate
588679-10-1

ethyl 2-(4-bromo-2-chlorophenoxy)acetate

Conditions
ConditionsYield
Stage #1: 4-bromo-2-chlorophenol With potassium carbonate In N,N-dimethyl-formamide at 60℃; for 1h;
Stage #2: chloroacetic acid ethyl ester In N,N-dimethyl-formamide at 20℃;
100%
4-adamantylphenol
29799-07-3

4-adamantylphenol

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

(4-adamantyl-1-yl-phenoxy) acetic acid ethyl ester
52804-25-8

(4-adamantyl-1-yl-phenoxy) acetic acid ethyl ester

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide100%
With potassium carbonate In N,N-dimethyl-formamide at 20℃;94.6%
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 12h; Inert atmosphere;94.6%
3-fluorophenol
372-20-3

3-fluorophenol

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

(3-fluoro-phenoxy)-acetic acid ethyl ester
777-70-8

(3-fluoro-phenoxy)-acetic acid ethyl ester

Conditions
ConditionsYield
With potassium carbonate In acetone for 24h; Heating / reflux;100%
With potassium carbonate In acetone for 8h; Reflux;70%
With potassium carbonate In acetonitrile for 2h; Reflux;
chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

methyl salicylate
119-36-8

methyl salicylate

methyl 2-(2-ethoxy-2-oxoethoxy)benzoate
22511-42-8

methyl 2-(2-ethoxy-2-oxoethoxy)benzoate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 30 - 65℃; for 18h;100%
With potassium carbonate In acetone for 11h; Reflux;94%
With potassium iodide; potassium carbonate In acetonitrile
With potassium carbonate In N,N-dimethyl-formamide at 65 - 75℃;
1-(5-fluoro-2-hydroxyphenyl)ethan-1-one
394-32-1

1-(5-fluoro-2-hydroxyphenyl)ethan-1-one

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

(2-acetyl-4-fluorophenoxy)acetic acid ethyl ester
34849-57-5

(2-acetyl-4-fluorophenoxy)acetic acid ethyl ester

Conditions
ConditionsYield
With potassium carbonate In acetone for 16h; Reflux; Inert atmosphere;100%
4-bromo-2-chlorophenol
3964-56-5

4-bromo-2-chlorophenol

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

ethyl 2-(4-bromo-2-chlorophenoxy)acetate
588679-10-1

ethyl 2-(4-bromo-2-chlorophenoxy)acetate

Conditions
ConditionsYield
Stage #1: 4-bromo-2-chlorophenol; chloroacetic acid ethyl ester With potassium carbonate In N,N-dimethyl-formamide at 60℃; for 1h; Inert atmosphere;
Stage #2: chloroacetic acid ethyl ester In N,N-dimethyl-formamide at 20℃;
100%
7-hydroxy-8-methyl-4-phenyl-chromen-2-one
21392-48-3

7-hydroxy-8-methyl-4-phenyl-chromen-2-one

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

ethyl (8-methyl-4-phenyl-2H-1-benzopyran-2-on-7-yloxy)-acetate
307547-31-5

ethyl (8-methyl-4-phenyl-2H-1-benzopyran-2-on-7-yloxy)-acetate

Conditions
ConditionsYield
With potassium carbonate In acetone for 24h; Reflux;100%
With potassium carbonate In acetone for 6h; Reflux;96.94%
5-(5-chloro-2-thienyl)-4-(2-methoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
1245623-59-9

5-(5-chloro-2-thienyl)-4-(2-methoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

ethyl [3-(5-chloro-2-thienyl)-4-(2-methoxyethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetate
1245623-60-2

ethyl [3-(5-chloro-2-thienyl)-4-(2-methoxyethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetate

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 80℃; for 6.5h;100%
With potassium carbonate In acetonitrile at 80℃; for 6.5h;100%
With potassium carbonate In acetonitrile at 80℃; for 6.5h;100%
chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

indeno[2,1-b]-1,4-oxazin-3(2H)-one,4,4a,9,9a-tetrahydro-,(4aR,9aS)-
862095-79-2

indeno[2,1-b]-1,4-oxazin-3(2H)-one,4,4a,9,9a-tetrahydro-,(4aR,9aS)-

Conditions
ConditionsYield
Stage #1: (1S,2R)-1-amino-2-indanol With sodium hydride In tetrahydrofuran at 0 - 70℃; for 0.666667h;
Stage #2: chloroacetic acid ethyl ester In tetrahydrofuran for 2.5h; Heating / reflux;
100%
With sodium hydride In tetrahydrofuran85%
bis[(2-pyridyl)methyl]amine
1539-42-0

bis[(2-pyridyl)methyl]amine

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

ethyl 2-(bis(pyridin-2-ylmethyl)amino)acetate

ethyl 2-(bis(pyridin-2-ylmethyl)amino)acetate

Conditions
ConditionsYield
With sodium carbonate In acetonitrile for 18h; Reflux;100%
Stage #1: bis[(2-pyridyl)methyl]amine With sodium hydrogencarbonate In acetonitrile for 0.166667h;
Stage #2: chloroacetic acid ethyl ester In acetonitrile for 5h; Reflux; Inert atmosphere;
With triethylamine In ethanol for 12h; Reflux;
chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

2-methoxyethyl isothiocyanate
38663-85-3

2-methoxyethyl isothiocyanate

4-aminoethylbenzene
589-16-2

4-aminoethylbenzene

(Z)-2-((4-ethylphenyl)imino)-3-(2-methoxyethyl)thiazolidin-4-one

(Z)-2-((4-ethylphenyl)imino)-3-(2-methoxyethyl)thiazolidin-4-one

Conditions
ConditionsYield
Stage #1: 2-methoxyethyl isothiocyanate; 4-aminoethylbenzene In ethanol at 78℃; for 12h; Knoevenagel Condensation;
Stage #2: chloroacetic acid ethyl ester With sodium acetate In ethanol at 78℃; for 5h; regioselective reaction;
100%
m-methylphenylacetic acid
621-36-3

m-methylphenylacetic acid

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

C13H16O4

C13H16O4

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran for 16h; Reflux; Inert atmosphere;100%
3-mercapto-5H-1,2,4-triazino[5,6-b]indole
28668-95-3

3-mercapto-5H-1,2,4-triazino[5,6-b]indole

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

ethyl ester of (1,2,4-triazino[5,6-b]indolyl-3-thio)acetic acid
189325-51-7

ethyl ester of (1,2,4-triazino[5,6-b]indolyl-3-thio)acetic acid

Conditions
ConditionsYield
With sodium In methanol; N,N-dimethyl-formamide at 60 - 100℃; for 15h; Alkylation;99.5%
Stage #1: 3-mercapto-5H-1,2,4-triazino[5,6-b]indole With potassium carbonate microwave irradiation;
Stage #2: chloroacetic acid ethyl ester for 0.0416667h; microwave irradiation;
89%
4-bromo-phenol
106-41-2

4-bromo-phenol

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

ethyl 2-(4-bromophenoxy)acetate
6964-29-0

ethyl 2-(4-bromophenoxy)acetate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 80℃;99.3%
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 4h;99%
With potassium carbonate In acetone Reflux;87%
oxirane
75-21-8

oxirane

[4-(diethylamino)phenyl]dichlorophosphine

[4-(diethylamino)phenyl]dichlorophosphine

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

ethyl [4-(diethylamino)phenyl](2-chloroethoxy)phosphoryl acetate

ethyl [4-(diethylamino)phenyl](2-chloroethoxy)phosphoryl acetate

Conditions
ConditionsYield
at -5 - 20℃; for 2h; Inert atmosphere;99.3%
4-Iodophenol
540-38-5

4-Iodophenol

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

4-iodophenoxyacetic acid ethyl ester
90794-33-5

4-iodophenoxyacetic acid ethyl ester

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; Inert atmosphere; Schlenk technique;99%
With potassium carbonate In N,N-dimethyl-formamide for 16h;98%
With potassium carbonate In N,N-dimethyl-formamide at 20℃;96%
With potassium carbonate In N,N-dimethyl-formamide at 20℃;
With potassium carbonate In N,N-dimethyl-formamide at 20℃;
bis(triphenylphosphineiminium) pentacarbonylmanganate(1-)
52542-59-3, 192520-17-5

bis(triphenylphosphineiminium) pentacarbonylmanganate(1-)

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

A

dimanganese decacarbonyl
10170-69-1

dimanganese decacarbonyl

B

pentacarbonylchloromanganese(I)
14100-30-2

pentacarbonylchloromanganese(I)

C

η1-(CH2COOEt) manganese pentacarbonyl

η1-(CH2COOEt) manganese pentacarbonyl

Conditions
ConditionsYield
In tetrahydrofuran (N2 or Ar); 25°C, rapid mixing; determination by NMR;A 1%
B 0%
C 99%
In chloroform-d1 (N2 or Ar); 25°C, rapid mixing; determination by NMR;A 1%
B 0%
C 99%
6-phenyl-[1,2,4]triazolo[4,3-b]pyridazine-3(2H)-thione
66129-30-4

6-phenyl-[1,2,4]triazolo[4,3-b]pyridazine-3(2H)-thione

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

ethyl-2-(6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-ylsulfanyl)acetate
1033038-23-1

ethyl-2-(6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-ylsulfanyl)acetate

Conditions
ConditionsYield
With sodium hydroxide In ethanol at 20℃; for 3h;99%
C19H20N2
946415-03-8

C19H20N2

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

C23H27N2O2(1+)*I(1-)
1255528-61-0

C23H27N2O2(1+)*I(1-)

Conditions
ConditionsYield
With sodium iodide In acetone at 20℃; for 18h;99%
2-azidobenzaldehyde
16714-25-3

2-azidobenzaldehyde

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

C11H11N3O3

C11H11N3O3

Conditions
ConditionsYield
With sodium In ethanol at 20℃; for 4h;99%
piperidine-4,4-diol hydrochloride
40064-34-4

piperidine-4,4-diol hydrochloride

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

ethyl 2-(4-oxopiperidin-1-yl)acetate

ethyl 2-(4-oxopiperidin-1-yl)acetate

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 75℃;99%
1-(tert-butyldimethylsilyl)-4-(4',4',5',5'-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indol-5-ol
103027-41-4

1-(tert-butyldimethylsilyl)-4-(4',4',5',5'-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indol-5-ol

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

C14H13IO3

C14H13IO3

Conditions
ConditionsYield
With potassium carbonate In acetone at 115℃; for 2h;99%
2,3-dimethoxyphenol
5150-42-5

2,3-dimethoxyphenol

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

ethyl (2,3-dimethoxyphenoxy)acetate
861085-96-3

ethyl (2,3-dimethoxyphenoxy)acetate

Conditions
ConditionsYield
Stage #1: 2,3-dimethoxyphenol With sodium hydride In tetrahydrofuran; dimethyl sulfoxide at 0℃; for 0.5h; Inert atmosphere;
Stage #2: chloroacetic acid ethyl ester In tetrahydrofuran; dimethyl sulfoxide at 20℃; for 15h; Inert atmosphere;
98.8%
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