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Shandong Xinhua Pharmaceutical Co.,Ltd

Appearance:colorless liquid Storage:tightly from light Package:200kg/drum Transportation:SEA Port:Qingdao

Methyl acetoacetate

Cas:105-45-3

Min.Order:1000 Kilogram

Negotiable

Type:Manufacturers

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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem’s R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantiti

Methyl acetoacetate suppliers in China

Cas:105-45-3

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Kono Chem Co.,Ltd

We are confident to supply you the best quality Methyl aceto acetate [Cas No.105-45-3] with competitive price,high quality and regular basis. 1. Specification of Methyl aceto acetate : Item Specific

Methyl acetoacetate

Cas:105-45-3

Min.Order:1 Kilogram

FOB Price: $90.0 / 100.0

Type:Other

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Methyl Acetoacetate supplier in China

Cas:105-45-3

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Jinan Finer Chemical Co., Ltd

Product description: Product name Methyl acetoacetate CAS number 105-45-3 Assay ≥99% Appearance Colorless transparent liquid Capacity 500mt/year Application Cellulose ether e

Methyl acetoacetate

Cas:105-45-3

Min.Order:100 Gram

FOB Price: $12.0

Type:Lab/Research institutions

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Hefei TNJ chemical industry co.,ltd

APIs Technology: Technology innovation is our eternal pursuit,or we will be left behind.Our technology experts,all from famous universities and institutes,has rich experience and high achievements in chemical research.This makes sure that our tec

Methyl acetoacetate

Cas:105-45-3

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

Methyl acetoacetate

Cas:105-45-3

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Methyl acetoacetate

Cas:105-45-3

Min.Order:1

Negotiable

Type:Other

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EAST CHEMSOURCES LIMITED

Founded in 2008, East Chemsources Limited is a professional manufacturer and supplier in food and chemical field in China. Through more than ten years development, our company has developed from single product at first to provide solution to final

Factory Supply Methyl Acetoacetate

Cas:105-45-3

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Large Stock 99.0% Methyl acetoacetate 105-45-3 Producer

Cas:105-45-3

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

Methyl Acetoacetate

Cas:105-45-3

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Acetoacetic acid methyl ester

Cas:105-45-3

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

CHENGDU YANXI is a comprehensive manufacturer and an international distribution of products throughout the world. Specialized in Scrap metal, Chemical raw materials, Paper products and color industry. We aim to become leading position in global dis

China supplier Pharmaceutical intermediates 105-45-3 Methyl acetoacetate

Cas:105-45-3

Min.Order:1 Gram

FOB Price: $3.0

Type:Trading Company

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Hubei DiBo chemical co., LTD

Name:Methyl acetoacetate The alias:Methyl acetoacetaten; Acetoacetic acid methyl ester; Butanoic acid, 3-oxo-, methyl ester:; methyl 3-oxobutanoate; MAA CAS NO:105-45-3 Molecular formula:C5H8O3 Molecular weight:116.1152 Product Quality 12 y

China/CAS:105-45-3/with best price

Cas:105-45-3

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

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Henan Tianfu Chemical Co., Ltd.

Product Name: Methyl acetoacetate Synonyms: 3-OXBUTANOIC ACID METHYL ESTER;3-OXOBUTANOIC ACID METHYL ESTER;3-OXOBUTYRIC ACID METHYL ESTER;ACETYL METHYL ACETATE;ACETOACETIC ACID METHYL ESTER;ACETOACETIC ESTER (METHYL);ACM;HYL ACETOACETATE CAS: 105

105-45-3 Methyl acetoacetate

Cas:105-45-3

Min.Order:1 Kilogram

FOB Price: $300.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Methyl acetoacetate CAS 105-45-3

Cas:105-45-3

Min.Order:1 Gram

FOB Price: $6.0 / 9.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 105-45-3 with fast shipping

Cas:105-45-3

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Name: Methyl acetoacetate Synonyms: Acetoacetic acid methyl ester CAS:105-45-3 MF: C5H8O3 Appearance: white powder Storage:Store in cool and dry place, away from sun light. Package: 25kgs/drum Application:Pharmaceutical Intermediate Transp

Methyl acetoacetate CAS:105-45-3

Cas:105-45-3

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Hangzhou Sartort Biopharma Co., Ltd

Appearance:liquid Storage:2-8°C Package:200kg/Drum Application:Methyl acetoacetate (MAA) is a starting material for the syntheses of alpha-substituted aceto- acetic esters and cyclic compounds, e.g. pyrazole, pyrimidine and coumarin derivatives. T

Methyl acetoacetate with high quality

Cas:105-45-3

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Butanoic acid, 3-oxo-,methyl ester 105-45-3

Cas:105-45-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Insecticide intermediate, Methyl acetoacetate CAS:105-45-3

Cas:105-45-3

Min.Order:1 Kilogram

FOB Price: $60.1 / 64.3

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

Methyl acetoacetate CAS:105-45-3 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic interme

Methyl acetoacetate CAS:105-45-3

Cas:105-45-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Butanoic acid, 3-oxo-,methyl ester

Cas:105-45-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Butanoic acid, 3-oxo-,methyl ester

Cas:105-45-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram

Methyl acetoacetate CAS NO.105-45-3

Cas:105-45-3

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Triumph International Development Limilted

Appearance:colorless liquid Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:Common products:Sea/Air/Co

Methyl acetoacetate

Cas:105-45-3

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

buy Methyl Acetoacetate/MAA/105-45-3 from Methyl Acetoacetate manufacturer

Cas:105-45-3

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

CAS105-45-3 Methyl acetoacetate

Cas:105-45-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Methyl acetoacetate

Cas:105-45-3

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

METHYL ACETOACETATE

Cas:105-45-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

methanol
67-56-1

methanol

5-acetyl-2,2-dimethyl-1,3-dioxane-4,6-dione
72324-39-1

5-acetyl-2,2-dimethyl-1,3-dioxane-4,6-dione

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

Conditions
ConditionsYield
for 0.0666667h; microwave irradiation;98%
for 5h; Reflux;
3-oxo-2-pyrrolidin-2-yl-butyric acid methyl ester hydrochloride

3-oxo-2-pyrrolidin-2-yl-butyric acid methyl ester hydrochloride

A

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

B

4-methyl-1,2,3,5a,6,7,8,8b-octahydro-3a,8a-diaza-as-indacene-5-carboxylic acid methyl ester

4-methyl-1,2,3,5a,6,7,8,8b-octahydro-3a,8a-diaza-as-indacene-5-carboxylic acid methyl ester

Conditions
ConditionsYield
With triethylamine In tetrahydrofuranA 49%
B 96%
methanol
67-56-1

methanol

carbon monoxide
201230-82-2

carbon monoxide

chloroacetone
78-95-5

chloroacetone

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

Conditions
ConditionsYield
With tributyl-amine; triphenylphosphine; bis(dibenzylideneacetone)-palladium(0) at 110℃; under 11250.9 Torr; for 1h; Product distribution; Further Variations:; Reagents; Temperatures; time;95%
With tributyl-amine; bis-triphenylphosphine-palladium(II) chloride at 110℃; under 7500.6 Torr; for 2h;80%
methanol
67-56-1

methanol

2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

Conditions
ConditionsYield
Esterification;92%
In 5,5-dimethyl-1,3-cyclohexadiene Reflux;77%
at 110 - 120℃;72%
In 5,5-dimethyl-1,3-cyclohexadiene at 150℃;
methanol
67-56-1

methanol

tert-butyl acetoacetate
1694-31-1

tert-butyl acetoacetate

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

Conditions
ConditionsYield
With di(n-butyl)tin oxide In methanol for 12h; Heating;90%
In xylene Heating;
-essigsaeure-methylester
109514-04-7

-essigsaeure-methylester

A

acetic acid methyl ester
79-20-9

acetic acid methyl ester

B

acetic acid-(1-methoxy-vinyl ester)
13253-76-4

acetic acid-(1-methoxy-vinyl ester)

C

tripropyltin chloride
2279-76-7

tripropyltin chloride

D

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

Conditions
ConditionsYield
With acetyl chlorideA 18%
B 46%
C 88%
D 9%
methanol
67-56-1

methanol

citric acid
77-92-9

citric acid

A

3-oxopentanedioic acid dimethyl ester
1830-54-2

3-oxopentanedioic acid dimethyl ester

B

dimethyl 2-methoxypropene-1,3-dicarboxylate
100009-70-9

dimethyl 2-methoxypropene-1,3-dicarboxylate

C

trimethyl aconitate
20820-77-3

trimethyl aconitate

D

trimethyl citrate
1587-20-8

trimethyl citrate

E

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

Conditions
ConditionsYield
Stage #1: citric acid With chlorosulfonic acid In dichloromethane at 10 - 15℃; for 5 - 6h;
Stage #2: methanol In dichloromethane at 3 - 35℃; for 2h; Conversion of starting material;
A 87.3%
B n/a
C n/a
D n/a
E n/a
α-bromoacetophenone
70-11-1

α-bromoacetophenone

6-methyl-4-oxo-2-thioxo-3,4-dihydro-2H-1,3-oxazine
2911-22-0

6-methyl-4-oxo-2-thioxo-3,4-dihydro-2H-1,3-oxazine

A

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

B

2-oxo-2-phenylethylthiocyanate
5399-30-4

2-oxo-2-phenylethylthiocyanate

Conditions
ConditionsYield
With sodium methylate In methanol for 12h; Ambient temperature;A 29%
B 87%
crotonic acid methyl ester
623-43-8

crotonic acid methyl ester

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

Conditions
ConditionsYield
With oxygen; nickel dichloride In methanol; water at 100℃; under 7500.75 Torr; for 12h; Reagent/catalyst; Solvent; Temperature; Autoclave;85.3%
acetic acid methyl ester
79-20-9

acetic acid methyl ester

acetyl chloride
75-36-5

acetyl chloride

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

Conditions
ConditionsYield
With lithium hexamethyldisilazane In tetrahydrofuran; hexane at -45℃; 1.) 30 min, 2.) 90 min;84%
acetic acid methyl ester
79-20-9

acetic acid methyl ester

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran for 20h; Heating;83%
With sodium methylate at 60℃;
With sodium anschliessend mit Essigsaeure oder Kohlendioxyd;
methanol
67-56-1

methanol

cycl-isopropylidene malonate
2033-24-1

cycl-isopropylidene malonate

acetyl chloride
75-36-5

acetyl chloride

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

Conditions
ConditionsYield
Stage #1: cycl-isopropylidene malonate; acetyl chloride With pyridine In dichloromethane at 20℃; for 2h;
Stage #2: methanol In dichloromethane for 2h; Further stages.;
75%
acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

Conditions
ConditionsYield
With methanol; water; oxygen; toluene-4-sulfonic acid; palladium dichloride In N,N-dimethyl acetamide at 80℃; under 4560.31 Torr; for 3h; Autoclave; regioselective reaction;73%
With tert.-butylhydroperoxide; sodium tetrachloropalladate(II) In acetic acid; tert-butyl alcohol at 50℃; for 3h;
4-methyleneoxetan-2-one
674-82-8

4-methyleneoxetan-2-one

methanol
67-56-1

methanol

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

Conditions
ConditionsYield
for 4.5h; Heating;72.5%
With dmap
1,4-diaza-bicyclo[2.2.2]octane at 20℃; for 0.343333h;
methanol
67-56-1

methanol

2,4-dioxo-6-methyl-3,4-dihydro-2H-1,3-oxazine
2911-21-9

2,4-dioxo-6-methyl-3,4-dihydro-2H-1,3-oxazine

A

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

B

methyl carbamate
598-55-0

methyl carbamate

Conditions
ConditionsYield
With triethylamine for 24h; Heating;A 70%
B 15%
tert-butyl acetoacetate
1694-31-1

tert-butyl acetoacetate

A

tert-butyl nitrate
926-05-6

tert-butyl nitrate

B

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

Conditions
ConditionsYield
With nitric acid In dichloromethane at 0℃; for 2h;A 60%
B 20%
6-methyl-4-oxo-2-thioxo-3,4-dihydro-2H-1,3-oxazine
2911-22-0

6-methyl-4-oxo-2-thioxo-3,4-dihydro-2H-1,3-oxazine

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

Conditions
ConditionsYield
With sodium methylate In methanol Ambient temperature;57%
1,2-Dimethyl-2-<(methoxycarbonyl)methyl>-1,3-dithiolanium-tetrafluoroborat

1,2-Dimethyl-2-<(methoxycarbonyl)methyl>-1,3-dithiolanium-tetrafluoroborat

A

2-methylsulfanyl-ethanethiol
22322-43-6

2-methylsulfanyl-ethanethiol

B

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

Conditions
ConditionsYield
With water at 40℃; for 0.0833333h;A 56%
B 13%
methyl but-3-enoate
3724-55-8

methyl but-3-enoate

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

Conditions
ConditionsYield
With manganese(IV) oxide; palladium dichloride In water; acetonitrile at 60℃; for 26h;52%
1-(3,5-dimethyl-1H-pyrazol-1-yl)ethanone
10199-63-0

1-(3,5-dimethyl-1H-pyrazol-1-yl)ethanone

bromoacetic acid methyl ester
96-32-2

bromoacetic acid methyl ester

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

Conditions
ConditionsYield
With zinc In tetrahydrofuran for 1h; Heating;50%
β-(N,N-dimethoxyamino)-isovaleric acid methyl ester
70569-71-0

β-(N,N-dimethoxyamino)-isovaleric acid methyl ester

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

Conditions
ConditionsYield
With boron trifluoride diethyl etherate In tetrachloromethane at 20℃;43.8%
1,3-bis(trimethylsiloxy)-1-methoxybuta-1,3-diene
74590-73-1

1,3-bis(trimethylsiloxy)-1-methoxybuta-1,3-diene

acetyl chloride
75-36-5

acetyl chloride

A

3,5-dioxohexanoic acid methyl ester
29736-80-9

3,5-dioxohexanoic acid methyl ester

B

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

Conditions
ConditionsYield
In diethyl ether at -78℃; for 4h; Yields of byproduct given;A 30%
B n/a
acetic acid methyl ester
79-20-9

acetic acid methyl ester

methyl (2SR,3RS)-1-benzyl-2-(indol-3-yl)piperidine-3-carboxylate

methyl (2SR,3RS)-1-benzyl-2-(indol-3-yl)piperidine-3-carboxylate

A

methyl 5-hydroxy-2-methoxycarbonyl-5-methyl-3-oxocyclohexen-1-acetate
1427722-55-1

methyl 5-hydroxy-2-methoxycarbonyl-5-methyl-3-oxocyclohexen-1-acetate

B

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

Conditions
ConditionsYield
Stage #1: acetic acid methyl ester With lithium hexamethyldisilazane In tetrahydrofuran at -78℃;
Stage #2: methyl (2SR,3RS)-1-benzyl-2-(indol-3-yl)piperidine-3-carboxylate In tetrahydrofuran at 0℃; for 15h;
A 27%
B 24%
3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one
771-03-9

3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one

A

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

B

3,5-dioxohexanoic acid methyl ester
29736-80-9

3,5-dioxohexanoic acid methyl ester

C

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

Conditions
ConditionsYield
With sodium methylate In methanol; benzene for 18h; Heating;A 7%
B 18%
C 16%
4-methyleneoxetan-2-one
674-82-8

4-methyleneoxetan-2-one

Dimethyl phosphite
868-85-9

Dimethyl phosphite

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

Conditions
ConditionsYield
sulfuric acid at 50℃; for 90h;13%
methanol
67-56-1

methanol

ethyl (E)-2-acetyl-3-oxo-5-phenylpent-4-enoate
76352-65-3

ethyl (E)-2-acetyl-3-oxo-5-phenylpent-4-enoate

sodium methylate
124-41-4

sodium methylate

A

acetic acid methyl ester
79-20-9

acetic acid methyl ester

B

methyl 3-oxo-5-phenyl-4-pentenoate
42996-88-3

methyl 3-oxo-5-phenyl-4-pentenoate

C

Methyl cinnamate
103-26-4

Methyl cinnamate

D

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

3-hydroxybutyric acid methyl ester
1487-49-6

3-hydroxybutyric acid methyl ester

A

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

B

acetone
67-64-1

acetone

Conditions
ConditionsYield
With copper at 330℃;
acetic acid methyl ester
79-20-9

acetic acid methyl ester

sodium methylate
124-41-4

sodium methylate

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

Conditions
ConditionsYield
at 57 - 80℃; Selbstkondensation;
cyclobutane-1,3-dione
15506-53-3

cyclobutane-1,3-dione

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

Conditions
ConditionsYield
With methanol; sodium methylate
acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

methyl 2-chloroacetoacetate
4755-81-1

methyl 2-chloroacetoacetate

Conditions
ConditionsYield
With sulfuryl dichloride; 2,2'-azobis(isobutyronitrile) In benzene at 20℃; for 2h; Inert atmosphere;100%
With sulfuryl dichloride In dichloromethane for 1h; Ambient temperature;98%
With ammonium cerium(IV) nitrate at 25 - 28℃; for 3h;85%
With sulfuryl dichloride
With sulfuryl dichloride at 0℃;
benzaldehyde
100-52-7

benzaldehyde

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

5-hydroxy-3-oxo-5-phenyl-valeric acid methyl ester
53063-63-1

5-hydroxy-3-oxo-5-phenyl-valeric acid methyl ester

Conditions
ConditionsYield
Stage #1: acetoacetic acid methyl ester With sodium hydride In tetrahydrofuran at 0℃; for 0.166667h;
Stage #2: With n-butyllithium In tetrahydrofuran; hexane at 20℃; for 0.333333h;
Stage #3: benzaldehyde In tetrahydrofuran; hexane at -78 - 20℃; for 1.08333h;
100%
Stage #1: acetoacetic acid methyl ester With sodium hydride In tetrahydrofuran at 20℃; for 0.5h; Inert atmosphere;
Stage #2: With n-butyllithium In tetrahydrofuran; hexane at -15 - -10℃; for 0.5h; Inert atmosphere;
Stage #3: benzaldehyde Further stages;
92%
Stage #1: acetoacetic acid methyl ester With sodium hydride In tetrahydrofuran at 20℃; for 0.5h; Inert atmosphere;
Stage #2: With n-butyllithium In tetrahydrofuran; hexane at -15 - -10℃; for 0.5h;
Stage #3: benzaldehyde Further stages;
92%
acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

prenyl bromide
870-63-3

prenyl bromide

methyl 7-methyl-3-oxooct-6-enoate
53067-23-5

methyl 7-methyl-3-oxooct-6-enoate

Conditions
ConditionsYield
Stage #1: acetoacetic acid methyl ester With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 0.166667h;
Stage #2: With n-butyllithium In tetrahydrofuran; mineral oil for 0.166667h;
Stage #3: prenyl bromide In tetrahydrofuran; mineral oil for 0.0833333h;
100%
With n-butyllithium; sodium hydride In tetrahydrofuran at 0 - 20℃;100%
With n-butyllithium; sodium hydride In tetrahydrofuran at 0℃;79%
1-(2-aminoethyl)pyrrolidine
7154-73-6

1-(2-aminoethyl)pyrrolidine

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

methyl 3-<(2'-(pyrrolidin-1"-yl)ethyl)amino>but-2-enoate

methyl 3-<(2'-(pyrrolidin-1"-yl)ethyl)amino>but-2-enoate

Conditions
ConditionsYield
In methanol at 25℃; for 3h;100%
4-(2-AMINOETHYL)MORPHOLINE
2038-03-1

4-(2-AMINOETHYL)MORPHOLINE

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

methyl 3-<(2'-morpholinoethyl)amino>but-2-enoate

methyl 3-<(2'-morpholinoethyl)amino>but-2-enoate

Conditions
ConditionsYield
In methanol at 25℃; for 10h;100%
benzaldehyde
100-52-7

benzaldehyde

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

dimethyl 4-phenyl-1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate
70677-78-0

dimethyl 4-phenyl-1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate

Conditions
ConditionsYield
With C23H3BF16N2O; ammonium acetate In toluene at 100℃; for 10h; Reagent/catalyst; Hantzsch Dihydropyridine Synthesis;100%
With ammonium acetate In ethanol at 60℃; for 0.5h; Catalytic behavior; Hantzsch Dihydropyridine Synthesis;98%
With ammonium acetate at 90℃; for 0.916667h; Hantzsch synthesis; Neat (no solvent);97%
methanol
67-56-1

methanol

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

3,3-bismethoxybutyric acid methyl ester
29267-46-7

3,3-bismethoxybutyric acid methyl ester

Conditions
ConditionsYield
With RuCl2-(S)-(2,2'-bis(diphenylphosphino)-1,1'-binaphthyl)(benzonitrile)2; hydrogen at 50℃; under 76000.1 Torr; for 48h;100%
4-aminobutyrylaldehyde diethylacetal
6346-09-4

4-aminobutyrylaldehyde diethylacetal

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

methyl 3-<(4',4'-diethoxybutyl)amino>but-2-enoate

methyl 3-<(4',4'-diethoxybutyl)amino>but-2-enoate

Conditions
ConditionsYield
In methanol at 25℃; for 3h;100%
acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

(E)-3-<2,4-dichloro-6-(phenylmethoxy)phenyl>-2-propenal
78443-74-0

(E)-3-<2,4-dichloro-6-(phenylmethoxy)phenyl>-2-propenal

methyl (E)-7-<2,4-dichloro-6-(phenylmethoxy)phenyl>-5-hydroxy-3-oxo-6-heptenoate
78443-77-3

methyl (E)-7-<2,4-dichloro-6-(phenylmethoxy)phenyl>-5-hydroxy-3-oxo-6-heptenoate

Conditions
ConditionsYield
With hydrogenchloride; n-butyllithium In tetrahydrofuran; hexane100%
With hydrogenchloride; n-butyllithium In tetrahydrofuran; hexane100%
With n-butyllithium; sodium hydride Yield given. Multistep reaction;
acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

Conditions
ConditionsYield
With cat; hydrogen In methanol; dichloromethane at 25℃; under 77572.2 Torr; for 48h;100%
With (S)-BiphempRuBr2; hydrogen In methanol at 80℃; under 7600 Torr; for 1h;100%
With hydrogen; [RuCl2(Sax-4,4'-bis(3-diphenylphosphineestra...)(DMF)]n In methanol at 100℃; under 76000 Torr; for 1h; Catalytic hydrogenation;100%
acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

A

(S)-3-hydroxybutyric acid methyl ester
53562-86-0

(S)-3-hydroxybutyric acid methyl ester

B

Methyl (R)-3-hydroxybutyrate
3976-69-0

Methyl (R)-3-hydroxybutyrate

Conditions
ConditionsYield
With Ru2Cl4-(S)-(2,2'-bis(diphenylphosphino)-1,1'-binaphthyl)2*NEt3; hydrogen In methanol at 35℃; under 76000.1 Torr; for 48h; Title compound not separated from byproducts;A 100%
B n/a
With <((R)-(1,1'-binaphthyl-2,2'-diyl)bis(diphenylphosphine))RuCl2>2NEt3; hydrogen In methanol at 35℃; under 76000.1 Torr; for 48h; Title compound not separated from byproducts;A n/a
B 100%
With hydrogen; Ru(BICP)Br2 In methanol at 40 - 65℃; under 750.075 - 3750.38 Torr;A n/a
B 95%
acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

Methyl (R)-3-hydroxybutyrate
3976-69-0

Methyl (R)-3-hydroxybutyrate

Conditions
ConditionsYield
With cat; hydrogen In methanol; dichloromethane at 25℃; under 77572.2 Torr; for 48h;100%
With (R)-MeOBiphepRuBr2; hydrogen In methanol at 50℃; under 15200 Torr; for 48h;100%
With (S)-4,12-bis(diphenylphosphino)-<2.2>paracyclophane-Ru(II)bis(trifluoroacetate); hydrogen; tetra-(n-butyl)ammonium iodide In methanol; water at -5℃; under 2585.7 Torr; for 18h;100%
acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

(1S,3R,5R,7R)-3-Chloro-10,10-dimethyl-3-phenyl-4-oxa-3λ4-selena-tricyclo[5.2.1.01,5]decane
156832-27-8

(1S,3R,5R,7R)-3-Chloro-10,10-dimethyl-3-phenyl-4-oxa-3λ4-selena-tricyclo[5.2.1.01,5]decane

2-[((1S,2R,4R)-2-Hydroxy-7,7-dimethyl-bicyclo[2.2.1]hept-1-ylmethyl)-phenyl-λ4-selanylidene]-3-oxo-butyric acid methyl ester

2-[((1S,2R,4R)-2-Hydroxy-7,7-dimethyl-bicyclo[2.2.1]hept-1-ylmethyl)-phenyl-λ4-selanylidene]-3-oxo-butyric acid methyl ester

Conditions
ConditionsYield
With triethylamine In dichloromethane for 1h; Ambient temperature;100%
4-methoxy-benzaldehyde
123-11-5

4-methoxy-benzaldehyde

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

urea
57-13-6

urea

5-methoxycarbonyl-4-(4-methoxyphenyl)-6-methyl-3,4-dihydropyrimidin-2(1H)-one
205999-87-7

5-methoxycarbonyl-4-(4-methoxyphenyl)-6-methyl-3,4-dihydropyrimidin-2(1H)-one

Conditions
ConditionsYield
With sulfuric acid; copper(l) chloride In methanol Biginelli Pyrimidone Synthesis; Reflux; Inert atmosphere;100%
With ytterbium(III) triflate at 100℃; for 0.333333h; Biginelli reaction;99%
With calcium chloride In ethanol for 2h; Biginelli reaction; Heating;98%
acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

Cysteamine
60-23-1

Cysteamine

(Z)-3-(2-Mercapto-ethylamino)-but-2-enoic acid methyl ester
503616-48-6

(Z)-3-(2-Mercapto-ethylamino)-but-2-enoic acid methyl ester

Conditions
ConditionsYield
for 24h; Ambient temperature;100%
acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

rac-methylbenzylamine
618-36-0

rac-methylbenzylamine

(Z)-3-(1-Phenyl-ethylamino)-but-2-enoic acid methyl ester
374559-41-8

(Z)-3-(1-Phenyl-ethylamino)-but-2-enoic acid methyl ester

Conditions
ConditionsYield
In methanol for 12h; Heating;100%
acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

benzylamine
100-46-9

benzylamine

3-benzylaminobut-2-enoic acid methyl ester
72002-24-5

3-benzylaminobut-2-enoic acid methyl ester

Conditions
ConditionsYield
In methanol for 12h; Heating;100%
In methanol at 20℃; for 0.5h;95%
With calcium bistrifluoroacetate at 20℃; for 0.5h; chemoselective reaction;95%
acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

(Z)-3-(2-Hydroxy-1-phenyl-ethylamino)-but-2-enoic acid methyl ester
374559-28-1

(Z)-3-(2-Hydroxy-1-phenyl-ethylamino)-but-2-enoic acid methyl ester

Conditions
ConditionsYield
In methanol for 12h; Heating;100%
(2S)-2-phenylglycinol
20989-17-7

(2S)-2-phenylglycinol

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

(Z)-3-((S)-2-Hydroxy-1-phenyl-ethylamino)-but-2-enoic acid methyl ester
476187-10-7

(Z)-3-((S)-2-Hydroxy-1-phenyl-ethylamino)-but-2-enoic acid methyl ester

Conditions
ConditionsYield
In methanol for 24h; Heating;100%
heptanal
111-71-7

heptanal

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

5-hydroxy-3-oxo-undecanoic acid methyl ester
869211-56-3

5-hydroxy-3-oxo-undecanoic acid methyl ester

Conditions
ConditionsYield
Stage #1: acetoacetic acid methyl ester With sodium hydride In tetrahydrofuran at 0℃; for 0.166667h;
Stage #2: With n-butyllithium In tetrahydrofuran; hexane at 20℃; for 0.333333h;
Stage #3: heptanal In tetrahydrofuran; hexane at -78 - 20℃; for 1.08333h;
100%
Stage #1: acetoacetic acid methyl ester With sodium hydride In tetrahydrofuran at 0℃;
Stage #2: With n-butyllithium In tetrahydrofuran at -78℃;
Stage #3: heptanal In tetrahydrofuran Further stages.;
acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

isobutyraldehyde
78-84-2

isobutyraldehyde

5-hydroxy-6-methyl-3-oxo-heptanoic acid methyl ester
55848-84-5

5-hydroxy-6-methyl-3-oxo-heptanoic acid methyl ester

Conditions
ConditionsYield
Stage #1: acetoacetic acid methyl ester With sodium hydride In tetrahydrofuran at 0℃; for 0.166667h;
Stage #2: With n-butyllithium In tetrahydrofuran; hexane at 20℃; for 0.333333h;
Stage #3: isobutyraldehyde In tetrahydrofuran; hexane at -78 - 20℃; for 1.08333h;
100%
Stage #1: acetoacetic acid methyl ester With lithium diisopropyl amide In tetrahydrofuran; hexane at -60 - 20℃; for 0.416667h; Weiler method; Inert atmosphere;
Stage #2: isobutyraldehyde In tetrahydrofuran; hexane at -60 - 20℃; for 4h; Weiler method; Inert atmosphere;
Stage #3: With water; ammonium chloride In tetrahydrofuran; hexane Inert atmosphere;
95%
Stage #1: acetoacetic acid methyl ester With sodium hydride In tetrahydrofuran at 0℃;
Stage #2: With n-butyllithium In tetrahydrofuran at -78℃;
Stage #3: isobutyraldehyde In tetrahydrofuran Further stages.;
(S)-2-(tert-butyldimethylsilyloxy)-1-phenylethylamine
120417-13-2

(S)-2-(tert-butyldimethylsilyloxy)-1-phenylethylamine

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

(Z)-3-[(S)-2-(tert-Butyl-dimethyl-silanyloxy)-1-phenyl-ethylamino]-but-2-enoic acid methyl ester
725250-70-4

(Z)-3-[(S)-2-(tert-Butyl-dimethyl-silanyloxy)-1-phenyl-ethylamino]-but-2-enoic acid methyl ester

Conditions
ConditionsYield
In methanol for 24h; Heating;100%
In methanol
phenethyl azide
6926-44-9

phenethyl azide

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

3-phenethylamino-but-2-enoic acid methyl ester

3-phenethylamino-but-2-enoic acid methyl ester

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In ethyl acetate at 20℃;100%
acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

Trimethylenediamine
109-76-2

Trimethylenediamine

3-[3-(2-methoxycarbonyl-1-methylvinylamino)-propylamino]but-2-enoic acid methyl ester

3-[3-(2-methoxycarbonyl-1-methylvinylamino)-propylamino]but-2-enoic acid methyl ester

Conditions
ConditionsYield
With silica-supported ferric hydrogensulfate/[Fe(HSO4)3*SiO2] In neat (no solvent) at 20℃; for 0.2h; regioselective reaction;100%
zirconium(IV) chloride at 20℃; for 0.25h;95%
With sulfated zirconia at 20℃; for 0.416667h;92%
acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

methyl 2-bromo-3-oxobutanoate
3600-18-8

methyl 2-bromo-3-oxobutanoate

Conditions
ConditionsYield
With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) In benzene at 20℃; for 2h; Inert atmosphere;100%
With N-Bromosuccinimide; toluene-4-sulfonic acid In dichloromethane at 20℃; for 0.416667h;94%
With ammonium cerium(IV) nitrate at 25 - 28℃; for 2.5h;87%
nonan-1-al
124-19-6

nonan-1-al

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

5-hydroxy-3-oxo-tridecanoic acid methyl ester

5-hydroxy-3-oxo-tridecanoic acid methyl ester

Conditions
ConditionsYield
Stage #1: acetoacetic acid methyl ester With sodium hydride In tetrahydrofuran at 0℃; for 0.166667h;
Stage #2: With n-butyllithium In tetrahydrofuran; hexane at 20℃; for 0.333333h;
Stage #3: nonan-1-al In tetrahydrofuran; hexane at -78 - 20℃; for 1.08333h;
100%
Stage #1: acetoacetic acid methyl ester With sodium hydride In tetrahydrofuran; mineral oil at 0 - 5℃; for 0.166667h;
Stage #2: With n-butyllithium In tetrahydrofuran; mineral oil at 5℃; for 0.166667h;
Stage #3: nonan-1-al In tetrahydrofuran; mineral oil at 5 - 10℃; for 0.5h;
tetrakis(triphenylphosphine) palladium(0)
14221-01-3

tetrakis(triphenylphosphine) palladium(0)

trityl tetrafluoroborate
341-02-6

trityl tetrafluoroborate

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

bis(triphenylphosphine)(methyl acetylacetato)palladium(II) tetrafluoroborate
80583-72-8

bis(triphenylphosphine)(methyl acetylacetato)palladium(II) tetrafluoroborate

Conditions
ConditionsYield
In acetone; benzene (N2); a soln. of CPh3BF4 and methyl acetoacetate in acetone was added to a soln. of the Pd complex in benzene, the soln. was agitated for 48 h; recrystn. from acetone-ether; elem. anal.;100%
acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

benzyl halide

benzyl halide

2-benzyl-3-oxo-butyric acid methyl ester
3666-82-8

2-benzyl-3-oxo-butyric acid methyl ester

Conditions
ConditionsYield
Stage #1: acetoacetic acid methyl ester With sodium hydride In tetrahydrofuran; mineral oil at 0 - 25℃; for 1h; Inert atmosphere;
Stage #2: benzyl halide In tetrahydrofuran; mineral oil at 0℃;
100%
Stage #1: acetoacetic acid methyl ester With sodium hydride In tetrahydrofuran; mineral oil at 20℃; Inert atmosphere;
Stage #2: benzyl halide In tetrahydrofuran; mineral oil at 20 - 40℃; Inert atmosphere;
Stage #1: acetoacetic acid methyl ester With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; Inert atmosphere;
Stage #2: benzyl halide In tetrahydrofuran; mineral oil for 12h; Inert atmosphere; Reflux;
2-aminopyridine
504-29-0

2-aminopyridine

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
1693-94-3

2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

Conditions
ConditionsYield
With bismuth(III) chloride at 100℃; for 3h; Catalytic behavior; Solvent; Temperature; Reagent/catalyst; Green chemistry;100%
With trichlorophosphate
N-BOC-1,2-diaminoethane
57260-73-8

N-BOC-1,2-diaminoethane

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

(Z)-methyl 3-((2-((tert.-butoxycarbonyl)amino)ethyl)amino)but-2-enoate
1240195-07-6

(Z)-methyl 3-((2-((tert.-butoxycarbonyl)amino)ethyl)amino)but-2-enoate

Conditions
ConditionsYield
With silica gel at 20℃; for 16h;100%
With silica gel In dichloromethane at 10 - 20℃; for 1h;127.9 g
With silica gel In dichloromethane at 10 - 20℃; for 1h;127.9 g
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