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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem produce Hydroxytyrosol 98% through Bio-fermentation which is the most advanced route makes the high purity of 98% and free of many impurites. Very important while used in food, cosmetic and pharma industries. As a leading manufactu

Hydroxytyrosol 98% Manufacturer/Bio-fermentation

Cas:10597-60-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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GIHI CHEMICALS CO.,LIMITED

factory low price Hydroxytyrosol(99%,fermented) 10597-60-1 free sample Product Description Product name:Hydroxytyrosol Botanical Source:Olive leaf CAS NO:1059

factory low price Hydroxytyrosol(99%,fermented) 10597-60-1 free sample

Cas:10597-60-1

Min.Order:1 Gram

FOB Price: $2.5

Type:Lab/Research institutions

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Vertexyn (Nanjing) Bioworks Co., Ltd.

Product Advantages: 1. Hydroxytyrosol is a competitive product of our company, and free samples can be applied. 2. It is available in stock for quick shipment. 3. Biological synthesis, natural, healthy, can be safely used in medicine, dyes, feed

Hangzhou Viablife Biotech CO.,LTD

Viablife is currently the only manufacturer in China who can provide commercial scale >99% purtiy Hydroxytyrosol using its leading Biosynthesis and Fermentation technology. Compared to plant-extracted Hydroxytyrosol, Viablife's hydroxytyrosol

hydroxytyrosol cas:10597-60-1 3-Hydroxytyrosol

Cas:10597-60-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Xi`an Eastling Biotech Co., Ltd.

10597-60-1 - Physico-chemical Properties Molecular Formula C8H10O3 Molar Mass 154.16 Density 1.321±0.06 g/cm3(Predicted) Boling Point 355.4±27.0 °C(Predicted) Flash Point

Top Quality Natural hydroxytyrosol/3,4-Dihydroxyphenylethanol

Cas:10597-60-1

Min.Order:1 Kilogram

FOB Price: $4.0 / 6.0

Type:Lab/Research institutions

inquiry

Sinoway Industrial Co., Ltd.

Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c

5%. 10%, 20%, 25%, 40% or customization Olive Leaf Extract Hydroxytyrosol 10597-60-1

Cas:10597-60-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Appearance A clear intense yellow, viscous, oily liquid Conforms Assay ≥

Top purity 3,4-Dihydroxyphenylethanol with high quality and best price cas:10597-60-1

Cas:10597-60-1

Min.Order:1 Gram

FOB Price: $2.0 / 5.0

Type:Manufacturers

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 3,4-Dihydroxyphenylethanol supplier in China

Cas:10597-60-1

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO

hydroxytyrosol manufacturer/supplier

Cas:10597-60-1

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 3,4-Dihydroxyphenylethanol

Cas:10597-60-1

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Content Natural Extract Hydroxytyrosol HACCP manufacturer

Cas:10597-60-1

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Xian Changyue Biological Technology Co., Ltd.

Our Advantages: 1. Free samples and unconditional hypothetical responses. 2.100% natural product, without any synthetic ingredients. 3. Direct sales from manufacturers, providing OEM and R&D services. 4. Complete certificates. 5. China's lead

Olive Leaf Extract, Canarium album Raeusch, Olea europaea, Hydroxytyrosol

Cas:10597-60-1

Min.Order:25 Kilogram

Negotiable

Type:Manufacturers

inquiry

Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech bio chemical products enterprises. The company's sales and marketing division is located in Shanghai, serving

lower price light yellow liquid 3,4-Dihydroxyphenylethanol CAS 10597-60-1

Cas:10597-60-1

Min.Order:1 Kilogram

FOB Price: $1850.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-(3,4-Dihydroxyphenyl)-ethanol

Cas:10597-60-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei yanxi chemical co.,LTD.

Hebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car

3,4-Dihydroxyphenylethanol

Cas:10597-60-1

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

High purity CAS 10597-60-1 3,4-Dihydroxyphenylethanol in stock Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...) 3.OLED intermediates

High purity CAS 10597-60-1 3,4-Dihydroxyphenylethanol in stock

Cas:10597-60-1

Min.Order:1 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

3,4-Dihydroxyphenylethanol

Cas:10597-60-1

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 10597-60-1 with fast shipping

Cas:10597-60-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

competitive price 3,4-Dihydroxyphenylethanol manufacturer 10597-60-1 in China

Cas:10597-60-1

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Name: 3,4-Dihydroxyphenylethanol Synonyms: 3,4-Dihydroxyphenethyl Alcohol CAS: 10597-60-1 MF: C8H10O3 Appearance:White powder Storage:Store in cool and dry place, away from sun light. Package:25kg/drum Application:Agrochemical Intermediates, Dyest

3,4-Dihydroxyphenylethanol CAS: 10597-60-1

Cas:10597-60-1

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Appearance:Slightly yellow viscous liquid Storage:R.T Package:25kg/Barrel Application:Antioxidant, pharmaceutical raw material Transportation:Express/Sea/Air Port:Any port in China

Hydroxytyrosol cas 10597-60-1

Cas:10597-60-1

Min.Order:1 Kilogram

FOB Price: $630.0 / 750.0

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:Brown fine powder Storage:Store in sealed containers at cool

Olive Leaf Extracts Hydroxytyrosol CAS 10597-60-1

Cas:10597-60-1

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1,In No Less five years exporting experience. 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Appearance:White powder Storage:storage in a dr

Hotsale Hydroxytyrosol with low price

Cas:10597-60-1

Min.Order:1 Kilogram

FOB Price: $9.0

Type:Lab/Research institutions

inquiry

HANWAYS CHEMPHARM CO.,LIMITED

We have two GMP facilities in Hubei Province and cooperative factories in Zhejiang Province We are concentrating on the R&D and technical service of APIs and pharmaceutical intermediates FDA Approved Appearance:Clear colorless Storage:2-8

High Antioxidant Activity 3, 4-Dihydroxyphenylethanol Powder Hydroxytyrosol in Stock

Cas:10597-60-1

Min.Order:1 Kilogram

FOB Price: $720.0

Type:Trading Company

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At pre

hydroxytyrosol/3,4-Dihydroxyphenylethanol CAS 10597-60-1

Cas:10597-60-1

Min.Order:1 Gram

FOB Price: $1.2 / 1.3

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

3,4-Dihydroxyphenylethanol CAS: 10597-60-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organ

3,4-Dihydroxyphenylethanol CAS: 10597-60-1

Cas:10597-60-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

3,4-Dihydroxyphenylethanol

Cas:10597-60-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Minimum Order Qty. 10 Gram Supply Ability 500 Kilograms/Month Storage store in cool, dry, ventilated place 20℃ Delivery Time 3 business days after payment Payment Term TT,western union,Paypal,MoneyGram Package 10g,20g,50g,100g,500g,1KGS,

Hydroxytyrosol CAS NO.10597-60-1

Cas:10597-60-1

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Wuhan Wonda Pharm Limited

1.High Quality: Quality is life. Quality is the most important element for all goods. We have a lab doing research in Wuhan China and produce sarms in bulk quantity. We have 8 years experience making all kinds of sarms. And all our old customers thr

Cosmetic Ingredients Anti-aging CAS 10597-60-1 Hydroxytyrosol Powder

Cas:10597-60-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

p-hydroxyphenethyl alcohol
501-94-0

p-hydroxyphenethyl alcohol

hydroxytyrosol
10597-60-1

hydroxytyrosol

Conditions
ConditionsYield
With polymer-supported IBX In dimethyl carbonate at 20℃; for 1h; chemoselective reaction;100%
With β-D-glucose; oxygen In aq. phosphate buffer at 37℃; pH=7.0; Enzymatic reaction;97.5%
Stage #1: p-hydroxyphenethyl alcohol at 20℃; for 1h;
Stage #2: With sodium dithionite; water for 0.5h;
90%
3,4-dihydroxyphenylacetate
102-32-9

3,4-dihydroxyphenylacetate

hydroxytyrosol
10597-60-1

hydroxytyrosol

Conditions
ConditionsYield
With (C4H9)NBH4 In tetrahydrofuran; dichloromethane at 20℃; for 2h;99%
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 60℃; for 8h;90%
With lithium aluminium tetrahydride In tetrahydrofuran for 2h; Reduction; Heating;79%
2-<3,4-bis(benzyloxy)phenyl>ethanol
96826-11-8

2-<3,4-bis(benzyloxy)phenyl>ethanol

hydroxytyrosol
10597-60-1

hydroxytyrosol

Conditions
ConditionsYield
With palladium on activated charcoal; hydrogen In tetrahydrofuran for 3h;98%
With hydrogen; palladium 10% on activated carbon In ethyl acetate at 20℃; for 2h; Inert atmosphere;96%
With palladium on activated charcoal; hydrogen In ethanol under 3800.26 Torr; for 24h;
2-(3,4-dihydroxyphenyl)acetic acid methyl ester
25379-88-8

2-(3,4-dihydroxyphenyl)acetic acid methyl ester

hydroxytyrosol
10597-60-1

hydroxytyrosol

Conditions
ConditionsYield
Stage #1: 2-(3,4-dihydroxyphenyl)acetic acid methyl ester With sodium tetrahydroborate In water at 0 - 24.5℃; for 8.16667h;
Stage #2: With hydrogenchloride; water at 0 - 5℃; for 0.25h; Product distribution / selectivity;
97%
Stage #1: 2-(3,4-dihydroxyphenyl)acetic acid methyl ester With lithium aluminium tetrahydride In tetrahydrofuran at 0℃; for 3.33333h; Heating / reflux;
Stage #2: With hydrogenchloride; water In tetrahydrofuran at 0℃; for 0.333333h; Product distribution / selectivity;
96.7%
Stage #1: 2-(3,4-dihydroxyphenyl)acetic acid methyl ester With lithium aluminium tetrahydride In tetrahydrofuran at 0℃; for 3.33333h; Heating / reflux;
Stage #2: With hydrogenchloride; water In tetrahydrofuran at 0℃; for 0.333333h;
96.7%
2-(2,2-dimethylbenzo[d][1,3]dioxol-5-yl)ethan-1-ol
119054-91-0

2-(2,2-dimethylbenzo[d][1,3]dioxol-5-yl)ethan-1-ol

hydroxytyrosol
10597-60-1

hydroxytyrosol

Conditions
ConditionsYield
With Amberlyst 15 In methanol for 3h; Heating;97%
Stage #1: 2-(2,2-dimethylbenzo[d][1,3]dioxol-5-yl)ethan-1-ol With water; acetic acid at 120℃; for 20h;
Stage #2: With water; sodium hydroxide In ethanol at 20℃; for 3h;
Stage #3: With hydrogenchloride In ethanol; water
94%
With Amberlyst 15 In methanol for 8h; Reflux;78%
2-(3,4-dihydroxyphenyl)ethyl acetate
69039-02-7

2-(3,4-dihydroxyphenyl)ethyl acetate

hydroxytyrosol
10597-60-1

hydroxytyrosol

Conditions
ConditionsYield
With hydrogenchloride In dichloromethane at 20℃; for 24h;96%
With hydrogenchloride In dichloromethane at 20℃; for 24h;95%
With hydrogenchloride In dichloromethane at 20℃; for 12h;94%
2-(3,4-dimethoxyphenyl)ethyl alcohol
7417-21-2

2-(3,4-dimethoxyphenyl)ethyl alcohol

hydroxytyrosol
10597-60-1

hydroxytyrosol

Conditions
ConditionsYield
Stage #1: 2-(3,4-dimethoxyphenyl)ethyl alcohol With aluminum (III) chloride In ethanethiol at 0 - 20℃; for 17h;
Stage #2: With hydrogenchloride; water In ethanethiol Cooling with ice;
95%
With aluminium trichloride In benzene Heating;
1,2-dibenzyloxy-4-(2-benzyloxyvinyl)benzene

1,2-dibenzyloxy-4-(2-benzyloxyvinyl)benzene

hydroxytyrosol
10597-60-1

hydroxytyrosol

Conditions
ConditionsYield
With 10 wt% Pd(OH)2 on carbon; hydrogen In methanol at 70℃; under 2585.81 Torr; for 12h; Solvent; Reagent/catalyst; Pressure; Green chemistry;95%
1-chloro-2-(3,4-dihydroxyphenyl)ethane
104693-00-7

1-chloro-2-(3,4-dihydroxyphenyl)ethane

hydroxytyrosol
10597-60-1

hydroxytyrosol

Conditions
ConditionsYield
With water for 4h; Microwave irradiation;94.8%
homovanillyl alcohol
2380-78-1

homovanillyl alcohol

hydroxytyrosol
10597-60-1

hydroxytyrosol

Conditions
ConditionsYield
Stage #1: homovanillyl alcohol With aluminum (III) chloride In ethanethiol at 0 - 20℃; for 42h;
Stage #2: With hydrogenchloride; water Cooling with ice;
94.7%
With sodium periodate In water; ethyl acetate Concentration; Reagent/catalyst; Temperature; Solvent; Time;78%
Stage #1: homovanillyl alcohol In tetrahydrofuran at 20℃; Darkness;
Stage #2: With sodium dithionite; water In tetrahydrofuran Darkness; chemoselective reaction;
42%
With polymer-supported IBX In dimethyl carbonate regioselective reaction;
Multi-step reaction with 3 steps
1: acetic acid / 12 h / 50 °C
2: boron tribromide / dichloromethane / -20 °C / Inert atmosphere
3: hydrogenchloride / dichloromethane / 24 h / 20 °C
View Scheme
2-hydroxy-3′,4′-dihydroxyacetophenone
29477-54-1

2-hydroxy-3′,4′-dihydroxyacetophenone

hydroxytyrosol
10597-60-1

hydroxytyrosol

Conditions
ConditionsYield
With water; hydrogen; palladium 10% on activated carbon In ethyl acetate at 40℃; under 3750.38 Torr; for 16h; Product distribution / selectivity;87.8%
With water; hydrogen; palladium 10% on activated carbon In tert-butyl methyl ether at 40℃; under 3750.38 Torr; for 7.5 - 25h; Product distribution / selectivity;87%
With hydrogen; 5% activated charcoal-supported ruthenium catalyst In tert-butyl methyl ether at 40℃; under 3750.38 Torr; Product distribution / selectivity;82.1%
3,4-dihydroxyphenethyl trifluoroacetate
1056355-55-5

3,4-dihydroxyphenethyl trifluoroacetate

hydroxytyrosol
10597-60-1

hydroxytyrosol

Conditions
ConditionsYield
With hydrogenchloride; water In tetrahydrofuran at 20℃; for 24h; Product distribution / selectivity;87%
Stage #1: 3,4-dihydroxyphenethyl trifluoroacetate With potassium hydroxide; water In tetrahydrofuran at 20℃; for 0.166667h;
Stage #2: With hydrogenchloride In water; ethyl acetate Product distribution / selectivity;
80%
3-bromo-4-hydroxyphenylethyl alcohol
196081-78-4

3-bromo-4-hydroxyphenylethyl alcohol

hydroxytyrosol
10597-60-1

hydroxytyrosol

Conditions
ConditionsYield
With water; copper 8-hydroxyquinolinate; potassium hydroxide at 100℃; for 6h; Reagent/catalyst; Temperature;86.52%
Multi-step reaction with 4 steps
1.1: copper(I) bromide; sodium methylate / methanol / 15 h / 100 °C
1.2: 12 h / 20 °C
2.1: acetic acid / 12 h / 50 °C
3.1: boron tribromide / dichloromethane / -20 °C / Inert atmosphere
4.1: hydrogenchloride / dichloromethane / 24 h / 20 °C
View Scheme
Multi-step reaction with 4 steps
1: copper(I) bromide; sodium methylate / methanol / 15 h / 100 °C
2: acetic acid / 12 h / 50 °C
3: boron tribromide / dichloromethane / -20 °C / Inert atmosphere
4: hydrogenchloride / dichloromethane / 24 h / 20 °C
View Scheme
3-amino-4-hydroxy-phenylethyl acetate

3-amino-4-hydroxy-phenylethyl acetate

hydroxytyrosol
10597-60-1

hydroxytyrosol

Conditions
ConditionsYield
With hydrogenchloride; sodium nitrite In water at 0 - 70℃; under 750.075 Torr; for 2.5h; Temperature;85.2%
2-(3',4'-dihydroxyphenyl)ethyl methyl carbonate
953422-34-9

2-(3',4'-dihydroxyphenyl)ethyl methyl carbonate

hydroxytyrosol
10597-60-1

hydroxytyrosol

Conditions
ConditionsYield
Stage #1: 2-(3',4'-dihydroxyphenyl)ethyl methyl carbonate With potassium hydroxide; water In tetrahydrofuran at 20℃; for 0.5h;
Stage #2: With hydrogenchloride In water; ethyl acetate Product distribution / selectivity;
85%
With potassium hydroxide; water In tetrahydrofuran at 20℃; for 0.5h;85%
oleuropeine
32619-42-4

oleuropeine

hydroxytyrosol
10597-60-1

hydroxytyrosol

Conditions
ConditionsYield
With sodium hydroxide for 2h;11%
With sulfuric acid at 37℃; for 3h;
Multi-step reaction with 2 steps
1.1: camphorsulfonic acid; 4 Angstroem molecular sieves / CHCl3 / 6 h / Heating
1.2: 13 mg / aq. NaOH / 2 h / Heating
2.1: 97 percent / Amberlyst 15 / methanol / 3 h / Heating
View Scheme
methanol
67-56-1

methanol

2′-acetylacteoside
94492-24-7

2′-acetylacteoside

A

hydroxytyrosol
10597-60-1

hydroxytyrosol

B

Methyl caffeate
3843-74-1, 67667-67-8

Methyl caffeate

Conditions
ConditionsYield
With acetyl chloride for 0.5h; Heating;
methanol
67-56-1

methanol

2'-acetylisoacteoside
112516-04-8

2'-acetylisoacteoside

A

hydroxytyrosol
10597-60-1

hydroxytyrosol

B

Methyl caffeate
3843-74-1, 67667-67-8

Methyl caffeate

Conditions
ConditionsYield
With acetyl chloride for 0.5h; Product distribution; Heating;
methanol
67-56-1

methanol

2-(3,4-dihydroxyphenyl)-ethyl O-α-L-rhamnopyranosyl-(1->3)-O-[β-D-clucopyranosyl-(1->6)]-2-O-acetyl-4-O-[(E)-caffeoyl]-β-D-glucopyranoside
112516-05-9

2-(3,4-dihydroxyphenyl)-ethyl O-α-L-rhamnopyranosyl-(1->3)-O-[β-D-clucopyranosyl-(1->6)]-2-O-acetyl-4-O-[(E)-caffeoyl]-β-D-glucopyranoside

A

hydroxytyrosol
10597-60-1

hydroxytyrosol

B

Methyl caffeate
3843-74-1, 67667-67-8

Methyl caffeate

Conditions
ConditionsYield
With acetyl chloride for 0.5h; Product distribution; Heating;
methanol
67-56-1

methanol

tubuloside D
112503-94-3

tubuloside D

A

hydroxytyrosol
10597-60-1

hydroxytyrosol

B

methyl 4-hydroxycinnamate
3943-97-3

methyl 4-hydroxycinnamate

Conditions
ConditionsYield
With acetyl chloride for 0.5h; Product distribution; Heating;
methanol
67-56-1

methanol

tubuloside C
112503-95-4

tubuloside C

A

hydroxytyrosol
10597-60-1

hydroxytyrosol

B

Methyl caffeate
3843-74-1, 67667-67-8

Methyl caffeate

Conditions
ConditionsYield
With acetyl chloride for 0.5h; Product distribution; Heating;
methanol
67-56-1

methanol

jionoside E

jionoside E

A

hydroxytyrosol
10597-60-1

hydroxytyrosol

B

methyl 4-hydroxycinnamate
3943-97-3

methyl 4-hydroxycinnamate

Conditions
ConditionsYield
pivaloyl chloride at 80℃; for 3h;
multifloroside
131836-10-7

multifloroside

hydroxytyrosol
10597-60-1

hydroxytyrosol

Conditions
ConditionsYield
With sodium hydroxide for 3.5h; Ambient temperature; Yield given;
cis-verbascoside
97747-56-3

cis-verbascoside

A

D-Glucose
2280-44-6

D-Glucose

B

L-rhamnose
73-34-7

L-rhamnose

C

caffeic acid
331-39-5

caffeic acid

D

hydroxytyrosol
10597-60-1

hydroxytyrosol

Conditions
ConditionsYield
With hydrogenchloride; potassium hydroxide 1.) MeOH, H2O, reflux, 3 h; 2.) MeOH, H2O, reflux;
(3,4-Diacetoxy-phenyl)-acetic acid methyl ester
35400-16-9

(3,4-Diacetoxy-phenyl)-acetic acid methyl ester

hydroxytyrosol
10597-60-1

hydroxytyrosol

Conditions
ConditionsYield
With lithium aluminium tetrahydride
forsythiaside
79916-77-1

forsythiaside

A

D-Glucose
2280-44-6

D-Glucose

B

L-rhamnose
73-34-7

L-rhamnose

C

caffeic acid
331-39-5

caffeic acid

D

hydroxytyrosol
10597-60-1

hydroxytyrosol

Conditions
ConditionsYield
With hydrogenchloride; sodium hydroxide Ambient temperature; hydrolysis;
rossicaside A
112664-03-6

rossicaside A

A

caffeic acid
331-39-5

caffeic acid

B

hydroxytyrosol
10597-60-1

hydroxytyrosol

Conditions
ConditionsYield
With hesperidinase In water at 32℃; for 48h; Product distribution;
acetyl chloride
75-36-5

acetyl chloride

A

hydroxytyrosol
10597-60-1

hydroxytyrosol

B

Methyl caffeate
3843-74-1, 67667-67-8

Methyl caffeate

Conditions
ConditionsYield
In methanol for 0.5h; Heating; Title compound not separated from byproducts;
echinacoside
737806-07-4

echinacoside

acetyl chloride
75-36-5

acetyl chloride

A

hydroxytyrosol
10597-60-1

hydroxytyrosol

B

Methyl caffeate
3843-74-1, 67667-67-8

Methyl caffeate

Conditions
ConditionsYield
In methanol for 0.5h; Heating; Title compound not separated from byproducts;
3,4-dihydroxyphenylacetate
102-32-9

3,4-dihydroxyphenylacetate

A

hydroxytyrosol
10597-60-1

hydroxytyrosol

B

3,4-dihydroxyphenylic acid ester of 2-(3,4-dihydroxyphenyl)ethanol

3,4-dihydroxyphenylic acid ester of 2-(3,4-dihydroxyphenyl)ethanol

Conditions
ConditionsYield
With sodium tetrahydroborate; diazomethyl-trimethyl-silane 1.) methanol, ether, hexane, RT, 0.5 h, 2.) methanol, ether, hexane, water, 0 deg C, 1.5 h; Yield given; Multistep reaction. Yields of byproduct given;
hydroxytyrosol
10597-60-1

hydroxytyrosol

acetic anhydride
108-24-7

acetic anhydride

2-(3,4-diacetoxyphenyl)-ethyl acetate
86214-97-3

2-(3,4-diacetoxyphenyl)-ethyl acetate

Conditions
ConditionsYield
In neat (no solvent) Molecular sieve; Microwave irradiation; Green chemistry;100%
With erbium(III) triflate at 20℃; for 2h; Inert atmosphere;80%
With pyridine; dmap In tetrahydrofuran at 20℃; for 7h;75%
hydroxytyrosol
10597-60-1

hydroxytyrosol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

C26H52O3Si3

C26H52O3Si3

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide at 20℃; for 3h;100%
vinyl octanoate
818-44-0

vinyl octanoate

hydroxytyrosol
10597-60-1

hydroxytyrosol

octanoic acid-3,4-dihydroxyphenylethyl ester
205241-38-9

octanoic acid-3,4-dihydroxyphenylethyl ester

Conditions
ConditionsYield
With Candida antarctica lipase In tert-butyl methyl ether at 40℃; for 1h; Enzymatic reaction;99%
With Novozym 435 at 40℃; for 1h; Enzymatic reaction;
With Candida antarctica lipase In tert-butyl methyl ether at 60℃; Enzymatic reaction;
hydroxytyrosol
10597-60-1

hydroxytyrosol

C8H7(2)H3O3

C8H7(2)H3O3

Conditions
ConditionsYield
With Amberlyst 15; water-d2 at 90℃; for 24h;98%
With Amberlyst 15; water-d2 at 90℃; for 24h; Substitution;
With nafion resin; water-d2 at 90℃; for 24h;
hydroxytyrosol
10597-60-1

hydroxytyrosol

4-methoxy-benzaldehyde
123-11-5

4-methoxy-benzaldehyde

1-(p-methoxyphenyl)-6,7-dihydroxyisochroman

1-(p-methoxyphenyl)-6,7-dihydroxyisochroman

Conditions
ConditionsYield
With molecular sieve; toluene-4-sulfonic acid In methanol at 4℃; for 24h; oxa-Pictet Spengler reaction;98%
With toluene-4-sulfonic acid In methanol at 4℃; for 24h;80%
for 0.166667h; oxa-Pictet-Spengler cyclisation;
hydroxytyrosol
10597-60-1

hydroxytyrosol

meta-hydroxybenzaldehyde
100-83-4

meta-hydroxybenzaldehyde

1-(m-hydroxyphenyl)-6,7-dihydroxyisochroman

1-(m-hydroxyphenyl)-6,7-dihydroxyisochroman

Conditions
ConditionsYield
With molecular sieve; toluene-4-sulfonic acid In methanol at 4℃; for 24h; oxa-Pictet Spengler reaction;98%
With toluene-4-sulfonic acid In methanol at 4℃; for 24h;80%
hydroxytyrosol
10597-60-1

hydroxytyrosol

acetone
67-64-1

acetone

6,7-dihydroxy-1,1-dimethylisochromane

6,7-dihydroxy-1,1-dimethylisochromane

Conditions
ConditionsYield
With toluene-4-sulfonic acid In methanol for 2h; Pictet-Spengler Synthesis; Reflux;98%
With toluene-4-sulfonic acid In methanol for 2h; Pictet-Spengler Synthesis; Reflux;98%
With toluene-4-sulfonic acid In methanol for 2h; Pictet-Spengler Synthesis; Reflux;98%
hexadecanoic acid ethyl ester
628-97-7

hexadecanoic acid ethyl ester

hydroxytyrosol
10597-60-1

hydroxytyrosol

palmitic acid-3,4-dihydroxyphenylethyl ester

palmitic acid-3,4-dihydroxyphenylethyl ester

Conditions
ConditionsYield
With Novozym 435 at 37℃;98%
hydroxytyrosol
10597-60-1

hydroxytyrosol

carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

2-(3',4'-dihydroxyphenyl)ethyl methyl carbonate
953422-34-9

2-(3',4'-dihydroxyphenyl)ethyl methyl carbonate

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene at 90℃; for 1h;98%
With sulfuric acid
hydroxytyrosol
10597-60-1

hydroxytyrosol

Hexanoyl chloride
142-61-0

Hexanoyl chloride

3-hydroxytyrosol trihexanoate

3-hydroxytyrosol trihexanoate

Conditions
ConditionsYield
With pyridine In toluene at 20℃; Cooling with ice;98%
In toluene for 0.75h; Cooling with ice;72%
hydroxytyrosol
10597-60-1

hydroxytyrosol

C8H7(3)H3O3

C8H7(3)H3O3

Conditions
ConditionsYield
With Amberlyst 15; tritium oxide at 90℃; for 24h;97%
vinyl n-butyrate
123-20-6

vinyl n-butyrate

hydroxytyrosol
10597-60-1

hydroxytyrosol

butyric acid-3,4-dihydroxyphenylethyl ester

butyric acid-3,4-dihydroxyphenylethyl ester

Conditions
ConditionsYield
With Candida antarctica lipase In various solvent(s) at 40℃; for 0.583333h;96.5%
With Novozym 435 at 40℃; for 1h; Enzymatic reaction;
With Candida antarctica lipase In tert-butyl methyl ether at 60℃; Enzymatic reaction;
vinyl propionate
105-38-4

vinyl propionate

hydroxytyrosol
10597-60-1

hydroxytyrosol

propionic acid 2-(3,4-dihydroxyphenyl)ethyl ester

propionic acid 2-(3,4-dihydroxyphenyl)ethyl ester

Conditions
ConditionsYield
With Candida antarctica lipase In various solvent(s) at 40℃; for 0.583333h;95.1%
hydroxytyrosol
10597-60-1

hydroxytyrosol

3-nitro-benzaldehyde
99-61-6

3-nitro-benzaldehyde

1-(3-nitro-phenyl)-isochroman-6,7-diol

1-(3-nitro-phenyl)-isochroman-6,7-diol

Conditions
ConditionsYield
With toluene-4-sulfonic acid In methanol at 4℃; for 24h;95%
hydroxytyrosol
10597-60-1

hydroxytyrosol

benzaldehyde
100-52-7

benzaldehyde

1-phenyl-6,7-dihydroxyisochroman

1-phenyl-6,7-dihydroxyisochroman

Conditions
ConditionsYield
With molecular sieve; toluene-4-sulfonic acid In methanol at 4℃; for 24h; oxa-Pictet Spengler reaction;95%
With toluene-4-sulfonic acid In methanol at 4℃; for 24h;60%
With sulfuric acid at 20℃; for 2.5h;55%
for 0.166667h; oxa-Pictet-Spengler cyclisation;
nonan-1-al
124-19-6

nonan-1-al

hydroxytyrosol
10597-60-1

hydroxytyrosol

1-(1'-octyl)-6,7-dihydroxyisochroman

1-(1'-octyl)-6,7-dihydroxyisochroman

Conditions
ConditionsYield
With molecular sieve; toluene-4-sulfonic acid In methanol at 4℃; for 24h; oxa-Pictet Spengler reaction;95%
for 0.166667h; oxa-Pictet-Spengler cyclisation;
hydroxytyrosol
10597-60-1

hydroxytyrosol

propionaldehyde
123-38-6

propionaldehyde

1-ethyl-6,7-dihydroxyisochroman

1-ethyl-6,7-dihydroxyisochroman

Conditions
ConditionsYield
With molecular sieve; toluene-4-sulfonic acid In methanol at 4℃; for 24h; oxa-Pictet Spengler reaction;95%
vinyl acetate
108-05-4

vinyl acetate

hydroxytyrosol
10597-60-1

hydroxytyrosol

2-(3,4-dihydroxyphenyl)ethyl acetate
69039-02-7

2-(3,4-dihydroxyphenyl)ethyl acetate

Conditions
ConditionsYield
With Candida antarctica lipase In various solvent(s) at 40℃; for 0.583333h;95%
With Novozym 435 at 40℃; for 1h; Enzymatic reaction;
hydroxytyrosol
10597-60-1

hydroxytyrosol

carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

3,4-dihydroxyphenethyl methyl ether
1156543-91-7

3,4-dihydroxyphenethyl methyl ether

Conditions
ConditionsYield
With Amberlyst 15 for 12h; Reflux;95%
stearic acid ethyl ester
111-61-5

stearic acid ethyl ester

hydroxytyrosol
10597-60-1

hydroxytyrosol

2-(3,4-dihydroxyphenyl)-ethyl stearate

2-(3,4-dihydroxyphenyl)-ethyl stearate

Conditions
ConditionsYield
With Novozym 435 at 37℃;94%

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