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Cas:112111-45-2
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
Cas:112111-45-2
Min.Order:1 Kilogram
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Type:Manufacturers
inquiryProduct Name: R-Benzhydrylsulfinylacetic acid CAS No.: 112111-45-2 Molecular Formula: C15H14O3S Molecular Weight: 274.33 Purity: 98.0% Min. Appearance: White or off-white crystalline powder We are a professional chemicals and APIs l
Cas:112111-45-2
Min.Order:1 Gram
FOB Price: $1.0
Type:Lab/Research institutions
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:112111-45-2
Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
Type:Manufacturers
inquiryTIANFUCHEM-- 112111-45-2--High purity (R)-(-)-Modafinil Acid in stock Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had established stable b
Cas:112111-45-2
Min.Order:1 Metric Ton
FOB Price: $2000.0
Type:Lab/Research institutions
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:112111-45-2
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiryOur Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con
Cas:112111-45-2
Min.Order:1 Kilogram
FOB Price: $1.0 / 10.0
Type:Trading Company
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:112111-45-2
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:112111-45-2
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Cas:112111-45-2
Min.Order:0
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Type:Lab/Research institutions
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Cas:112111-45-2
Min.Order:0
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Type:Lab/Research institutions
inquirySuperior quality, moderate price & quick delivery. Appearance:off-White Solid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:as per your request Application:Used as Pharmaceutical Intermediates, etc. Tran
Cas:112111-45-2
Min.Order:1 Kilogram
Negotiable
Type:Trading Company
inquiryOur Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an
Cas:112111-45-2
Min.Order:0
Negotiable
Type:Trading Company
inquiryGMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,
GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation
Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai
Cas:112111-45-2
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryLower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe
Cas:112111-45-2
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryhigh purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou
Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands
Cas:112111-45-2
Min.Order:100 Gram
Negotiable
Type:Lab/Research institutions
inquiryOur clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS
Cas:112111-45-2
Min.Order:0
Negotiable
Type:Manufacturers
inquiryhigh purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou
Cas:112111-45-2
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiry1,we produce and sell good chemicals around the world.2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%.3,our staff consists of highly qualified in
Cas:112111-45-2
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryAnsciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali
Cas:112111-45-2
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryAmoychem is committed to providing the top-quality chemical products and services Internationally. We offer our customers with friendly, professional service and reliable, high performance products that have been manufactured according to the accredi
Cas:112111-45-2
Min.Order:0
Negotiable
Type:Other
inquiryR-Benzhydrylsulfinylacetic acid cas 112111-45-2Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express
Cas:112111-45-2
Min.Order:0
Negotiable
Type:Other
inquiryfactory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
Cas:112111-45-2
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryhight degree of purityAppearance:COA mentioned Storage:COA mentioned Package:Standard or custom package Application:hight degree of purity Transportation:Express/Sea/Air Port:Any port in China
112111-45-2 Application:intermediate
Cas:112111-45-2
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiry(benzhydrylthio)acetic acid
(R)-Modafinil acid
Conditions | Yield |
---|---|
With NADP; sodium hydroxide In isopropyl alcohol at 35℃; pH=8.54; Catalytic behavior; Concentration; Solvent; Reagent/catalyst; Temperature; pH-value; Alkaline conditions; enantioselective reaction; | 100% |
Multi-step reaction with 4 steps 1.1: 99 percent / H2SO4 / Heating 2.1: H2SO4; 2-propanol; aq. H2O2 / methanol / 20 °C 3.1: 62.1 g / NaOH; H2O / ethanol / 1 h / 20 °C 4.1: (R)-(+)-α-methylbenzylamine / H2O / Heating 4.2: aq. HCl / pH 2 View Scheme |
2-((R)-Diphenyl-methanesulfinyl)-1-((R)-4-phenyl-2-thioxo-thiazolidin-3-yl)-ethanone
(R)-Modafinil acid
Conditions | Yield |
---|---|
With lithium hydroxide In tetrahydrofuran; water at 0 - 20℃; | 96% |
(R)-Modafinil acid
Conditions | Yield |
---|---|
With trifluoroacetic acid In acetonitrile at 60℃; for 3h; Inert atmosphere; enantioselective reaction; | 84% |
modafinil acid
A
(R)-Modafinil acid
B
(+)-(S)-(diphenylmethanesulfinyl)acetic acid
Conditions | Yield |
---|---|
Stage #1: modafinil acid With (S)-1-phenyl-ethylamine In water Heating; Stage #2: With hydrogenchloride pH=2; | A 12.6 g B n/a |
Stage #1: modafinil acid With (R)-1-phenyl-ethyl-amine In water Heating; Stage #2: With hydrogenchloride pH=2; | A n/a B 17.0 g |
modafinil acid
(R)-Modafinil acid
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 44.5 percent / 4-(dimethylamino)pyridine; 1,3-dicyclohexylcarbodiimide / CH2Cl2 2: 96 percent / lithium hydroxide / tetrahydrofuran; H2O / 0 - 20 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1.1: 99 percent / trifluoroacetic acid / 3 h / 20 °C 2.1: 99 percent / H2SO4 / Heating 3.1: H2SO4; 2-propanol; aq. H2O2 / methanol / 20 °C 4.1: 62.1 g / NaOH; H2O / ethanol / 1 h / 20 °C 5.1: (R)-(+)-α-methylbenzylamine / H2O / Heating 5.2: aq. HCl / pH 2 View Scheme |
(diphenylmethyl)(ethyl acetate)sulfide
(R)-Modafinil acid
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: H2SO4; 2-propanol; aq. H2O2 / methanol / 20 °C 2.1: 62.1 g / NaOH; H2O / ethanol / 1 h / 20 °C 3.1: (R)-(+)-α-methylbenzylamine / H2O / Heating 3.2: aq. HCl / pH 2 View Scheme |
(diphenylmethyl)(ethyl acetate)sulfoxide
(R)-Modafinil acid
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: 62.1 g / NaOH; H2O / ethanol / 1 h / 20 °C 2.1: (R)-(+)-α-methylbenzylamine / H2O / Heating 2.2: aq. HCl / pH 2 View Scheme |
(-)-α-methylbenzylamine
modafinil acid
A
(S)-modafinic acid*(S)-α-methylbenzylamine
B
(R)-Modafinil acid
Conditions | Yield |
---|---|
In isopropyl alcohol at 20℃; Product distribution / selectivity; Heating / reflux; | |
In ethyl acetate at 20℃; Product distribution / selectivity; Heating / reflux; | |
In N,N-dimethyl-formamide; acetone at 20℃; Product distribution / selectivity; Heating / reflux; |
(benzhydrylthio)acetic acid
A
(R)-Modafinil acid
B
(+)-(S)-(diphenylmethanesulfinyl)acetic acid
Conditions | Yield |
---|---|
With 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate In tetrachloromethane at 20℃; for 48h; Title compound not separated from byproducts.; | |
Stage #1: (benzhydrylthio)acetic acid With 1,8-diazabicyclo[5.4.0]undec-7-ene In toluene at 0 - 5℃; for 0.5h; Stage #2: With (1S)-(+)-(10-camphorsulfonyl)-oxaziridine In toluene at 25 - 30℃; |
(+)-(S)-(diphenylmethanesulfinyl)acetic acid
(R)-Modafinil acid
Conditions | Yield |
---|---|
In dimethyl sulfoxide at 90℃; for 17h; Product distribution / selectivity; | |
In N,N-dimethyl-formamide at 90℃; for 17h; Product distribution / selectivity; |
2-(benzhydrylsulfinyl)acetic acid (-)-α-methylbenzylamine
(R)-Modafinil acid
Conditions | Yield |
---|---|
With hydrogenchloride In water at 20℃; |
methyl iodide
(R)-Modafinil acid
(R)-(-)-methyl (diphenylmethanesulfinyl)-acetate
Conditions | Yield |
---|---|
With potassium carbonate In acetone Reflux; | 70% |
With potassium carbonate In acetone Heating; | 68% |
With potassium carbonate In acetone for 4h; Reflux; |
(R)-Modafinil acid
Nuvigil
Conditions | Yield |
---|---|
With Bacillus subtilis var. niger IFO-3180 In N,N-dimethyl-formamide at 28℃; for 168h; | 60% |
Multi-step reaction with 2 steps 1: 68 percent / K2CO3 / acetone / Heating 2: 55 percent / aq. NH4OH; NH4Cl / methanol / 20 °C View Scheme | |
Multi-step reaction with 2 steps 1: potassium carbonate / acetone / Reflux 2: ammonium hydroxide; ammonium chloride / methanol / 20 °C View Scheme | |
Stage #1: (R)-Modafinil acid With methanol; thionyl chloride at 0 - 20℃; for 3h; Stage #2: With ammonium hydroxide In methanol; water at 0℃; Reagent/catalyst; Temperature; Time; |
methanol
(R)-Modafinil acid
(R)-(-)-methyl (diphenylmethanesulfinyl)-acetate
Conditions | Yield |
---|---|
With hydrogenchloride In water at 20℃; for 1 - 24h; Product distribution / selectivity; Heating / reflux; | |
With thionyl chloride at 0 - 20℃; for 3 - 20h; Product distribution / selectivity; |
(R)-Modafinil acid
(+)-(S)-(diphenylmethanesulfinyl)acetic acid
Conditions | Yield |
---|---|
Stage #1: (R)-Modafinil acid With indium; pivaloyl chloride In isopropyl alcohol at 15 - 30℃; for 3h; Stage #2: With hydrogenchloride In water; isopropyl alcohol at 20℃; for 0.5h; Product distribution / selectivity; | |
With perchloric acid; sodium bromide In water; ethyl acetate at 20℃; for 20h; Product distribution / selectivity; | |
With perchloric acid; sodium bromide In water; acetonitrile at 20℃; for 20h; Product distribution / selectivity; |
Conditions | Yield |
---|---|
Stage #1: (R)-Modafinil acid With triethylamine In dichloromethane at 5 - 30℃; for 0.5h; Stage #2: isobutyl chloroformate In dichloromethane at 0 - 25℃; for 3.25h; |
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