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hangzhou verychem science and technology co.ltd

Product name: PSEUDOTROPINE Cas No: 135-97-7 Assay: 99%min Hangzhou Verychem Science And Technology Co. Ltd. was set up in year 2004, it’s a young but fast growing company. In the twelve years

Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

Pseudotropine Manufacturer/High quality/Best price/In stock

Cas:135-97-7

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Β-Tropine supplier in China

Cas:135-97-7

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% Pseudotropine 135-97-7 ISO Producer

Cas:135-97-7

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Hubei DiBo chemical co., LTD

Name:pseudotropine CAS NO: 135-97-7 Grade:Medical scientific research and export Molecular formula:C8H15NO Molecular weight:141.2108 Product Quality 12 years of chemical raw materials Mature operation of the industry System stability Data

pseudotropine/cas:135-97-7/Raw material spot

Cas:135-97-7

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

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Henan Tianfu Chemical Co., Ltd.

Pseudotropine Basic information Product Name: Pseudotropine Synonyms: exo-8-methyl-8-azabicyclo[3.2.1]octan-3-ol;PSEUDOTROPANOL;PSEUDOTROPINE;1-alpha-h,5-alpha-h-tropan-3-beta-ol;3-b

Pseudotropine

Cas:135-97-7

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

High Quality Pseudotropine CAS 135-97-7 Factory Supply

Cas:135-97-7

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 135-97-7 with fast shipping

Cas:135-97-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

TIANFU-CHEM - Pseudotropine

Cas:135-97-7

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages High purity, all above 98.5%, no impurities after dissolution We will test each batch to ensure quality OEM and private brand services designed for free Various cap colors available We can also provide MT1 peptide powd

PseudotropineCAS135-97-7

Cas:135-97-7

Min.Order:1 Kilogram

FOB Price: $8.0 / 10.0

Type:Trading Company

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Hangzhou Sartort Biopharma Co., Ltd

Appearance:White crystalline powder Storage:R.T Package:25kg/drum Application:Intermediates Transportation:Express/Sea/Air Port:Any port in China

Pseudotropine beta-Tropanol cas 135-97-7

Cas:135-97-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:white or off-white powder Storage:Store in sealed containers

Pseudotropine CAS No 135-97-7

Cas:135-97-7

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Pseudotropine 135-97-7

Cas:135-97-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Pseudotropine,99%

Cas:135-97-7

Min.Order:1 Kilogram

FOB Price: $42.0 / 55.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

Pseudotropine CAS:135-97-7 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates

Pseudotropine CAS:135-97-7

Cas:135-97-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Pseudotropine

Cas:135-97-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

Pseudotropine

Cas:135-97-7

Min.Order:1 Kilogram

FOB Price: $10.0 / 100.0

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Pseudotropine

Cas:135-97-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

cas 135-97-7 Pseudotropine

Cas:135-97-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

β-Tropanol

Cas:135-97-7

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Pseudotropine

Cas:135-97-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Β-Tropine

Cas:135-97-7

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:25kg/drum, or as per your request. Application:Used as Pharmaceutical Intermediates Tr

Pseudotropine

Cas:135-97-7

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providing h

Factory Supply pseudotropine

Cas:135-97-7

Min.Order:0

Negotiable

Type:Other

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

3-TROPANOL,99.0+%

Cas:135-97-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: Beta-Tropine CAS No.:135-97-7 Molecule Formula:C8H15NO Molecule Weight:141.21 Purity: 99% Package: 25kg/drum Description:White crystalline powder Manufacture Standards:Enterprise Standard TESTING ITEMS

High Quality Beta-Tropine in stock

Cas:135-97-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Top Purity SupplierPseudotropine

Cas:135-97-7

Min.Order:0

Negotiable

Type:Trading Company

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Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

Pseudotropine

Cas:135-97-7

Min.Order:1 Milligram

Negotiable

Type:Trading Company

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Shanghai Minstar Chemical Co., Ltd

Pseudotropine Chemical Properties Melting point 109° Boiling point bp 241° density 0.9938 (rough estimate) refractive index 1.4811 (estimate) storage temp. Sealed in dry,2-8°C pka 3.80(at 15℃) CAS DataBase Reference

Pseudotropine

Cas:135-97-7

Min.Order:1 Gram

FOB Price: $66.0

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

TIANFU-CHEM - Pseudotropine

Cas:135-97-7

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Synthetic route

formaldehyd
50-00-0

formaldehyd

(1R,3R,5S)-8-azabicyclo[3.2.1]octan-3-ol
501-33-7

(1R,3R,5S)-8-azabicyclo[3.2.1]octan-3-ol

pseudotropine
135-97-7

pseudotropine

Conditions
ConditionsYield
With sodium tetrahydroborate91%
tropinone
532-24-1

tropinone

pseudotropine
135-97-7

pseudotropine

Conditions
ConditionsYield
With lithium borohydride In tetrahydrofuran a) -78 deg C, 6 h, b) RT, overnight;85%
With 2-methyl-propan-1-ol; sodium; toluene
With lithium borohydride In tetrahydrofuran at -78℃;
N-(ethoxycarbonyl)nortropacocaine
95687-86-8

N-(ethoxycarbonyl)nortropacocaine

pseudotropine
135-97-7

pseudotropine

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran Heating;67%
With lithium aluminium tetrahydride In tetrahydrofuran for 6h; Heating;67%
tropinone hydrochloride
4827-85-4

tropinone hydrochloride

A

8,8'-dimethyl-3,3'-dihydroxy-3,3'-bi(8-azabicyclo<3.2.1>octyl)
85089-40-3

8,8'-dimethyl-3,3'-dihydroxy-3,3'-bi(8-azabicyclo<3.2.1>octyl)

B

8-methyl-3-hydroxy-3-(1-hydroxy-1-methylethyl)-8-azabicyclo<3.2.1>octane

8-methyl-3-hydroxy-3-(1-hydroxy-1-methylethyl)-8-azabicyclo<3.2.1>octane

C

3-tropanol
120-29-6

3-tropanol

D

pseudotropine
135-97-7

pseudotropine

Conditions
ConditionsYield
With isopropyl alcohol for 22h; Heating; Irradiation; PRK-2 mercury-quartz lamp;A 5%
B 22%
C 46%
D 32%
tropinone hydrochloride
4827-85-4

tropinone hydrochloride

isopropyl alcohol
67-63-0

isopropyl alcohol

A

8,8'-dimethyl-3,3'-dihydroxy-3,3'-bi(8-azabicyclo<3.2.1>octyl)
85089-40-3

8,8'-dimethyl-3,3'-dihydroxy-3,3'-bi(8-azabicyclo<3.2.1>octyl)

B

8-methyl-3-hydroxy-3-(1-hydroxy-1-methylethyl)-8-azabicyclo<3.2.1>octane

8-methyl-3-hydroxy-3-(1-hydroxy-1-methylethyl)-8-azabicyclo<3.2.1>octane

C

3-tropanol
120-29-6

3-tropanol

D

pseudotropine
135-97-7

pseudotropine

Conditions
ConditionsYield
for 22h; Heating; Irradiation; PRK-2 mercury-quartz lamp;A 5%
B 22%
C 46%
D 32%
3-iodo-tropane

3-iodo-tropane

A

tropidine
529-18-0

tropidine

B

pseudotropine
135-97-7

pseudotropine

Conditions
ConditionsYield
With hydrogenchloride at 185 - 190℃; im Rohr;
tropinone
532-24-1

tropinone

B

pseudotropine
135-97-7

pseudotropine

Conditions
ConditionsYield
elektrolytischen Reduktion,in alkal.Loesung;
elektrolytischen Reduktion,in alkal.Loesung;weitere Nebenprodukt:Tropan;
With hydrogen iodide; zinc at 0℃; weitere Nebenprodukt:Tropan;
tropinone
532-24-1

tropinone

A

3-tropanol
120-29-6

3-tropanol

B

pseudotropine
135-97-7

pseudotropine

Conditions
ConditionsYield
With aluminum isopropoxide; isopropyl alcohol
With sodium tetrahydroborate In ethanol for 1h;A 91 mg
B 519 mg
tropinone
532-24-1

tropinone

A

8,8'-dimethyl-3,3'-dihydroxy-3,3'-bi(8-azabicyclo<3.2.1>octyl)
85089-40-3

8,8'-dimethyl-3,3'-dihydroxy-3,3'-bi(8-azabicyclo<3.2.1>octyl)

B

pseudotropine
135-97-7

pseudotropine

Conditions
ConditionsYield
With sodium amalgam
pseudotropine
135-97-7

pseudotropine

Conditions
ConditionsYield
elektrolytischen Oxydation in saurer oder swach alkalischer Loesung;arbeitet ohne Diaphragma an der Kathode;
tropane-3exo-ol-8-oxide
32663-70-0, 32663-71-1, 35772-43-1

tropane-3exo-ol-8-oxide

pseudotropine
135-97-7

pseudotropine

Conditions
ConditionsYield
With sulfur dioxide
tropinone
532-24-1

tropinone

pseudotropine
135-97-7

pseudotropine

Conditions
ConditionsYield
With potassium phosphate buffer; 2-aminoethanoic acid hydrochloride; tris hydrochloride; NADPH; tropinone reductase enzym for 2h;
Conditions
ConditionsYield
In water for 720h; Irradiation; decomposition in aq. solution; stability after storage in glass and polyethylene containers under various conditions (pH-value, temp., oxidative effects, irradiation);
Conditions
ConditionsYield
In water at 100℃; for 15h; Mechanism; pH=8-9; also 100 degC, pH=3-4, 184 h; 100 degC, pH=6-7, 320 h; 90 degC, 20 d; 90 degC, 14 month's;
trans-3β-(cinnamoyloxy)tropane
126394-78-3

trans-3β-(cinnamoyloxy)tropane

A

(E)-3-phenylacrylic acid
140-10-3

(E)-3-phenylacrylic acid

B

pseudotropine
135-97-7

pseudotropine

Conditions
ConditionsYield
With barium dihydroxide Product distribution;
tropinone
532-24-1

tropinone

platinum/charcoal

platinum/charcoal

pseudotropine
135-97-7

pseudotropine

Conditions
ConditionsYield
in mineralsaurer Loesung.Hydrogenation;
tropinone
532-24-1

tropinone

platinum

platinum

pseudotropine
135-97-7

pseudotropine

Conditions
ConditionsYield
in mineralsaurer Loesung.Hydrogenation;
hydrogenchloride
7647-01-0

hydrogenchloride

tropinone
532-24-1

tropinone

sodium amalgam

sodium amalgam

pseudotropine
135-97-7

pseudotropine

sodium pentylate solution

sodium pentylate solution

pseudotropine
135-97-7

pseudotropine

ethanol
64-17-5

ethanol

tropinone
532-24-1

tropinone

sodium

sodium

pseudotropine
135-97-7

pseudotropine

tropane-3exo-ol-8-oxide
32663-70-0, 32663-71-1, 35772-43-1

tropane-3exo-ol-8-oxide

sulfur dioxide

sulfur dioxide

pseudotropine
135-97-7

pseudotropine

tigloidine

tigloidine

pseudotropine
135-97-7

pseudotropine

Conditions
ConditionsYield
With barium dihydroxide
(+/-)-2-(carbomethoxy)-3-tropinone
36127-17-0

(+/-)-2-(carbomethoxy)-3-tropinone

sodium amalgam

sodium amalgam

acid

acid

A

pseudotropine
135-97-7

pseudotropine

B

(+-)-ecgonine methyl ester

(+-)-ecgonine methyl ester

C

(+-)-pseudoecgonine methyl ester

(+-)-pseudoecgonine methyl ester

dihydrogen peroxide
7722-84-1

dihydrogen peroxide

acetone
67-64-1

acetone

tropacocain
537-26-8

tropacocain

A

tropacocaine-N oxide
35772-45-3

tropacocaine-N oxide

B

pseudotropine
135-97-7

pseudotropine

α-tropidine hydrobromide

α-tropidine hydrobromide

A

tropidine
529-18-0

tropidine

B

pseudotropine
135-97-7

pseudotropine

Conditions
ConditionsYield
With water at 200℃; im Rohr;
With mineral acid at 200℃; im Rohr;
3-iodo-tropane

3-iodo-tropane

hydrogenchloride
7647-01-0

hydrogenchloride

B

pseudotropine
135-97-7

pseudotropine

Conditions
ConditionsYield
at 185 - 190℃; im Rohr;
homatropine
114173-36-3

homatropine

aq. barium hydroxide solution

aq. barium hydroxide solution

B

pseudotropine
135-97-7

pseudotropine

Conditions
ConditionsYield
at 60℃;
homatropine
114173-36-3

homatropine

mineral acid

mineral acid

B

pseudotropine
135-97-7

pseudotropine

hydrogenchloride
7647-01-0

hydrogenchloride

tropacocain
537-26-8

tropacocain

A

benzoic acid
65-85-0

benzoic acid

B

pseudotropine
135-97-7

pseudotropine

hydrobromide of tropidine

hydrobromide of tropidine

B

pseudotropine
135-97-7

pseudotropine

Conditions
ConditionsYield
With hydrogen bromide at 35℃; Erhitzen des Reaktionsprodukts mit Wasser auf 160grad;
pseudotropine
135-97-7

pseudotropine

trichloromethyl chloroformate
503-38-8

trichloromethyl chloroformate

exo-8-methyl-8-azabicyclo<3.2.1>oct-3-yl chloroformate hydrochloride
123259-28-9

exo-8-methyl-8-azabicyclo<3.2.1>oct-3-yl chloroformate hydrochloride

Conditions
ConditionsYield
In acetonitrile 1.) O deg C, 30 min, 2.) RT, 24 h;95%
pseudotropine
135-97-7

pseudotropine

tropinone
532-24-1

tropinone

Conditions
ConditionsYield
With pyridinium chlorochromate In dichloromethane at 20℃;95%
benzoyl chloride
98-88-4

benzoyl chloride

pseudotropine
135-97-7

pseudotropine

tropacocain
537-26-8

tropacocain

Conditions
ConditionsYield
With triethylamine In toluene for 4h; Reflux;90%
With TEA In toluene for 3h; Heating;
methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

pseudotropine
135-97-7

pseudotropine

endo-3-methanesulfonyloxy-8-methyl-8-azabicyclo[3.2.1]octane
35136-87-9

endo-3-methanesulfonyloxy-8-methyl-8-azabicyclo[3.2.1]octane

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane at -5℃; for 1.25h; Product distribution / selectivity;88.1%
Stage #1: pseudotropine With triethylamine In tetrahydrofuran at 20℃; for 0.5h;
Stage #2: methanesulfonyl chloride In tetrahydrofuran at -5 - 15℃; Product distribution / selectivity;
88%
With triethylamine In dichloromethane at -10.4 - -3℃; for 1.25 - 4.58h; Conversion of starting material;78.1%
With triethylamine In dichloromethane at -10.4 - -3℃; for 0.5 - 4.58h; Product distribution / selectivity;78.1%
allyl bromide
106-95-6

allyl bromide

pseudotropine
135-97-7

pseudotropine

(1R,3s,5S)-3-(allyloxy)-8-methyl-8-azabicyclo[3.2.1]octane

(1R,3s,5S)-3-(allyloxy)-8-methyl-8-azabicyclo[3.2.1]octane

Conditions
ConditionsYield
Stage #1: pseudotropine With sodium hydride In tetrahydrofuran; N,N-dimethyl-formamide for 0.0833333h; Inert atmosphere;
Stage #2: allyl bromide In tetrahydrofuran; N,N-dimethyl-formamide at 20℃; for 16h; Inert atmosphere;
75%
Stage #1: pseudotropine With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 2.16667h;
Stage #2: allyl bromide In N,N-dimethyl-formamide at 0 - 20℃;
44%
m-Fluorobenzonitrile
403-54-3

m-Fluorobenzonitrile

pseudotropine
135-97-7

pseudotropine

3-endo-(8-methyl-8-azabicyclo[3.2.1]octan-3-yloxy)benzonitrile
1007457-06-8

3-endo-(8-methyl-8-azabicyclo[3.2.1]octan-3-yloxy)benzonitrile

Conditions
ConditionsYield
Stage #1: pseudotropine With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃;
Stage #2: m-Fluorobenzonitrile In tetrahydrofuran; mineral oil at 50℃;
73%
N-(4'-hydroxy-[1,1'-biphenyl]-4-yl)-3',6-dimethoxy-[1,1'-biphenyl]-3-carboxamide

N-(4'-hydroxy-[1,1'-biphenyl]-4-yl)-3',6-dimethoxy-[1,1'-biphenyl]-3-carboxamide

pseudotropine
135-97-7

pseudotropine

3',6-dimethoxy-N-(4'-(((1R,3s,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl)oxy)-[1,1'-biphenyl]-4-yl)-[1,1'-biphenyl]-3-carboxamide

3',6-dimethoxy-N-(4'-(((1R,3s,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl)oxy)-[1,1'-biphenyl]-4-yl)-[1,1'-biphenyl]-3-carboxamide

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran for 2h;71%
2-chloro-5-phenyl-[1,3,4]thiadiazole
13373-11-0

2-chloro-5-phenyl-[1,3,4]thiadiazole

pseudotropine
135-97-7

pseudotropine

C16H19N3OS

C16H19N3OS

Conditions
ConditionsYield
Stage #1: pseudotropine With sodium hydride In tetrahydrofuran at 20℃; for 0.5h;
Stage #2: 2-chloro-5-phenyl-[1,3,4]thiadiazole In tetrahydrofuran at 50℃; for 2h;
66%
14-O-[(acetylthio)acetyl]mutilin
1227078-70-7

14-O-[(acetylthio)acetyl]mutilin

methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

pseudotropine
135-97-7

pseudotropine

[[(3-exo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]thio]-,(3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester
224452-64-6

[[(3-exo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]thio]-,(3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester

Conditions
ConditionsYield
Stage #1: methanesulfonyl chloride; pseudotropine With triethylamine In acetone at 0 - 25℃; for 3h;
Stage #2: 14-O-[(acetylthio)acetyl]mutilin With ethylenediamine In toluene at 35℃; for 24h; Product distribution / selectivity; Inert atmosphere;
41%
6-fluoroindole-3-carboxylic acid
23077-44-3

6-fluoroindole-3-carboxylic acid

pseudotropine
135-97-7

pseudotropine

(1R,3R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 6-fluoro-1H-indole-3-carboxylate

(1R,3R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 6-fluoro-1H-indole-3-carboxylate

Conditions
ConditionsYield
Stage #1: 6-fluoroindole-3-carboxylic acid With oxalyl dichloride In N,N-dimethyl-formamide at 0℃; for 2h; Inert atmosphere;
Stage #2: pseudotropine In dichloromethane at 0 - 20℃;
39.6%
1H-indole-3-carboxylic acid
771-50-6

1H-indole-3-carboxylic acid

pseudotropine
135-97-7

pseudotropine

tropisetron

tropisetron

Conditions
ConditionsYield
Stage #1: 1H-indole-3-carboxylic acid With thionyl chloride In dichloromethane at 20℃; for 2h; Inert atmosphere; Reflux;
Stage #2: pseudotropine With n-butyllithium In tetrahydrofuran; hexane at 5 - 20℃; for 16.5h; Inert atmosphere;
34%
4-fluoro-1-iodobenzene
352-34-1

4-fluoro-1-iodobenzene

trifluoroacetic acid
76-05-1

trifluoroacetic acid

pseudotropine
135-97-7

pseudotropine

(1R,3R,5S)-3-(4-iodophenoxy)-8-methyl-8-azabicyclo[3.2.1]octane trifluoroacetate

(1R,3R,5S)-3-(4-iodophenoxy)-8-methyl-8-azabicyclo[3.2.1]octane trifluoroacetate

Conditions
ConditionsYield
Stage #1: 4-fluoro-1-iodobenzene; pseudotropine With sodium hydride In N,N-dimethyl-formamide; mineral oil at 85℃; for 24h; Inert atmosphere;
Stage #2: trifluoroacetic acid
33%
1-chloro-4-(chloro(phenyl)methyl)benzene
134-83-8

1-chloro-4-(chloro(phenyl)methyl)benzene

pseudotropine
135-97-7

pseudotropine

3β-<(4'-chlorophenyl)phenylmethoxy>tropane hydrochloride

3β-<(4'-chlorophenyl)phenylmethoxy>tropane hydrochloride

Conditions
ConditionsYield
at 160℃;31%
benzophenone
119-61-9

benzophenone

pseudotropine
135-97-7

pseudotropine

A

tetraphenylethane-1,2-diol
464-72-2

tetraphenylethane-1,2-diol

B

(1R,3S,5S)-8-(2-Hydroxy-2,2-diphenyl-ethyl)-8-aza-bicyclo[3.2.1]octan-3-ol

(1R,3S,5S)-8-(2-Hydroxy-2,2-diphenyl-ethyl)-8-aza-bicyclo[3.2.1]octan-3-ol

Conditions
ConditionsYield
In benzene at 22 - 25℃; for 19h; Irradiation;A n/a
B 31%
mutilin 14-methanesulfonyloxyacetate

mutilin 14-methanesulfonyloxyacetate

pseudotropine
135-97-7

pseudotropine

mutilin 14-(exo-8-methyl-8-azabicyclo[3.2.1]oct-3-ylsulfanyl)-acetate

mutilin 14-(exo-8-methyl-8-azabicyclo[3.2.1]oct-3-ylsulfanyl)-acetate

Conditions
ConditionsYield
17%
acetone
67-64-1

acetone

pseudotropine
135-97-7

pseudotropine

A

2,3-dimethyl-2,3-butane diol
76-09-5

2,3-dimethyl-2,3-butane diol

B

(1R,3S,5S)-8-(2-Hydroxy-2-methyl-propyl)-8-aza-bicyclo[3.2.1]octan-3-ol

(1R,3S,5S)-8-(2-Hydroxy-2-methyl-propyl)-8-aza-bicyclo[3.2.1]octan-3-ol

Conditions
ConditionsYield
In benzene at 22 - 25℃; for 19h; Irradiation;A n/a
B 15%
1-bromo-butane
109-65-9

1-bromo-butane

pseudotropine
135-97-7

pseudotropine

8anti-butyl-3exo-hydroxy-8syn-methyl-nortropanium; bromide
17812-42-9

8anti-butyl-3exo-hydroxy-8syn-methyl-nortropanium; bromide

Conditions
ConditionsYield
With acetonitrile
diphenylacetic acid chloride
1871-76-7

diphenylacetic acid chloride

pseudotropine
135-97-7

pseudotropine

3exo-diphenylacetoxy-tropane
119113-39-2

3exo-diphenylacetoxy-tropane

2-Chlor-2,2-diphenylacetamid
722-96-3

2-Chlor-2,2-diphenylacetamid

pseudotropine
135-97-7

pseudotropine

A

N,N'-dibenzhydryl-urea
6744-64-5

N,N'-dibenzhydryl-urea

B

diphenyl-tropane-3exo-yloxy-acetic acid amide

diphenyl-tropane-3exo-yloxy-acetic acid amide

Conditions
ConditionsYield
With sodium carbonate; benzene at 125℃;
cinnamic acid anhydride
538-56-7

cinnamic acid anhydride

pseudotropine
135-97-7

pseudotropine

trans-3β-(cinnamoyloxy)tropane
126394-78-3

trans-3β-(cinnamoyloxy)tropane

Conditions
ConditionsYield
With water
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