We are both manufacture and trader , have very good quality and competitive price, meanwhile , we have exported to other market 100kg every month. Appearance:white powder Storage:Nomal Package:25kg/drum Application:intermediates Transportation:Nor
Cas:320-51-4
Min.Order:1 Kilogram
FOB Price: $280.0
Type:Manufacturers
inquiryAs a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch
Cas:320-51-4
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryProduct Description Name 5-Amino-2-chlorobenzotrifluoride CAS 320-51-4 Assay 99% Appearance Yellowish crystal or liquid Capacity 500mt/year Min.package 100gram Standard
Cas:320-51-4
Min.Order:1 Kilogram
FOB Price: $2.0
Type:Lab/Research institutions
inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
Cas:320-51-4
Min.Order:0 Metric Ton
Negotiable
Type:Manufacturers
inquiryHebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car
Cas:320-51-4
Min.Order:1 Metric Ton
FOB Price: $1.0 / 2.0
Type:Manufacturers
inquiryhigh quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai
Cas:320-51-4
Min.Order:1 Kilogram
Negotiable
Type:Manufacturers
inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
Cas:320-51-4
Min.Order:1
Negotiable
Type:Other
inquiry1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:320-51-4
Min.Order:1 Gram
FOB Price: $0.1
Type:Manufacturers
inquiryCangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap
Cas:320-51-4
Min.Order:1 Kilogram
FOB Price: $5.0
Type:Manufacturers
inquiryColorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on
Cas:320-51-4
Min.Order:1 Metric Ton
Negotiable
Type:Manufacturers
inquiryHigh quality. Factory supply. In stock. Best price.1.Quick response within 24 hours;2.Best quality in your requirement;?3.We pay more attention on delivery time, and usually ship on time;4.Under the premise of safety and effectiveness, we can produce
Cas:320-51-4
Min.Order:0
Negotiable
Type:Trading Company
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:320-51-4
Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
Type:Manufacturers
inquiryHigh purity CAS 320-51-4 4-Chloro-alpha,alpha,alpha-trifluoro-m-toluidine in stock Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...)
Cas:320-51-4
Min.Order:1 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiryOur advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva
Cas:320-51-4
Min.Order:1 Kilogram
FOB Price: $9.0 / 99.0
Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:320-51-4
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiryName: 2-Chloro-5-Aminobenzotrifluoride Synonyms: 5-amino-2-chlorobenzotrifluoride CAS:320-51-4 MF: C8H2Cl2F6 Appearance:Colorless transparent liquid, Storage: Preserve in well-closed, light-resistant and airtight containers. Package: 25kgs/dr
Cas:320-51-4
Min.Order:1 Kilogram
FOB Price: $1.0
Type:Other
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:320-51-4
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryHangzhou Huarong Pharm Co., Ltd. established since 2009 , has been always focusing on supplying products and services to our clients in the field of small molecule drug. Huarong Pharm has built platforms for the research, development and manufac
Cas:320-51-4
Min.Order:1 Gram
FOB Price: $1.0 / 2.0
Type:Lab/Research institutions
inquiry4-Chloro-alpha,alpha,alpha-trifluoro-m-toluidine CAS:320-51-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in
Cas:320-51-4
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:320-51-4
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryAdvantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&
Cas:320-51-4
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Appearance:White to pinkish crystalline powder Storage:R.T Package:25kg/drum Application:used as pharmaceutical and pesticide intermediates Transportation:Express/Sea/Air Port:Any port in China
Cas:320-51-4
Min.Order:1 Kilogram
FOB Price: $1.0
Type:Lab/Research institutions
inquiryBest quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia
Our advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We have s
Cas:320-51-4
Min.Order:10 Kilogram
Negotiable
Type:Trading Company
inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Cas:320-51-4
Min.Order:0 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryregorafenib intermediate 5-amino-2-chlorobenzotrifluoride CAS:320-51-4 We are top supplier of regorafenib intermediates. Application:Regorafenib intermediate Port:shanghai seaport
Cas:320-51-4
Min.Order:0 Metric Ton
Negotiable
Type:Other
inquiryCompany Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments
Cas:320-51-4
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Cas:320-51-4
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryConditions | Yield |
---|---|
With sodium tetrahydroborate; TPGS-750-M In tetrahydrofuran; water at 20℃; for 1h; Catalytic behavior; Reagent/catalyst; | 98% |
With sodium tetrahydroborate In tetrahydrofuran; water at 20℃; for 2h; Inert atmosphere; Green chemistry; chemoselective reaction; | 94% |
With sodium tetrahydroborate; iron; water at 20℃; for 2h; | 94% |
Conditions | Yield |
---|---|
With copper dichloride; 1-hexyl-3-methylimidazol-1-ium chloride at 40℃; for 8h; regioselective reaction; | 94% |
Conditions | Yield |
---|---|
With ammonium hydroxide; potassium phosphate; copper(l) iodide; N1,N2-bis(5-methyl-[1,1'-biphenyl]-2-yl)oxalamide In water; dimethyl sulfoxide at 110℃; for 24h; Inert atmosphere; | 84% |
Multi-step reaction with 2 steps 1: hydrazine hydrate; pyridine / ethyl acetate; dichloromethane / 4 h / 130 °C / Autoclave 2: Raney nickel / methanol / 1 h / Reflux View Scheme |
Conditions | Yield |
---|---|
Stage #1: 5-bromo-2-chlorobenzotrifluoride With magnesium In tetrahydrofuran Inert atmosphere; Stage #2: With C10H17NO In tetrahydrofuran; toluene at -45℃; for 2h; Inert atmosphere; Stage #3: With ammonium chloride In tetrahydrofuran; water; toluene Inert atmosphere; | 61% |
4-chloropicolinamide
4-amino-phenol
A
4-(4-aminophenoxy)-2-pyridinecarboxamide
B
4-chloro-3-trifluoromethyl-aniline
Conditions | Yield |
---|---|
With potassium tert-butylate; sodium chloride In methanol; hexane; ethyl acetate; N,N-dimethyl-formamide | A 58% B n/a |
With potassium tert-butylate; sodium chloride In methanol; hexane; ethyl acetate; N,N-dimethyl-formamide | A 58% B n/a |
With potassium tert-butylate; sodium chloride In methanol; hexane; ethyl acetate; N,N-dimethyl-formamide | A 58% B n/a |
1-(4-bromophenyl)-3-(4-chloro-3-(trifluoromethyl)phenyl)-5-thioxoimidazolidine-2,4-dione
benzylamine
A
3-benzyl-5-(benzylimino)-1-(4-bromophenyl)imidazolidine-2,4-dione
B
4-chloro-3-trifluoromethyl-aniline
Conditions | Yield |
---|---|
for 1h; Reflux; | A 51% B n/a |
Conditions | Yield |
---|---|
With sodium hydroxide In ethanol; water at 83℃; for 24h; Irradiation; further reagents, further conditions; |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 60 percent / HNO3; H2SO4 / 0.5 h / 50 - 60 °C 2: 65 percent / NaSH*9H2O; NaHCO3 / methanol; H2O / 1 h / Heating View Scheme | |
Multi-step reaction with 2 steps 1: HNO3, H2SO4 2: H2 / PtO2 View Scheme | |
Multi-step reaction with 2 steps 1: nitric acid; sulfuric acid / 1 h / Heating 2: palladium 10% on activated carbon; hydrogen / methanol / 2 h / 20 °C View Scheme | |
Multi-step reaction with 2 steps 1: acetic anhydride; nitric acid / 3 h / 10 - 12 °C 2: iron(III) chloride hexahydrate; hydrazine hydrate / ethanol / 3 h / Reflux View Scheme | |
Multi-step reaction with 2 steps 1: sulfuric acid; nitric acid / water / 18 h / 0 - 20 °C / Inert atmosphere; Schlenk technique 2: iron; ammonium chloride; hydrogenchloride / ethanol; water / 2 h / 80 °C / Inert atmosphere; Schlenk technique View Scheme |
5-bromo-2-chlorobenzotrifluoride
A
C14H7Cl2F6N
B
4-chloro-3-trifluoromethyl-aniline
Conditions | Yield |
---|---|
With dicyclohexyl(2',4',6'-triisopropyl-5-methoxy-3,4,6-trimethyl-[1,1'-biphenyl]-2-yl)phosphine; C50H70NO4PPdS; C50H70NO4PPdS; dicyclohexyl(2',4',6'-triisopropyl-4-methoxy-3,5,6-trimethyl-[1,1'-biphenyl]-2-yl)phosphine; ammonia; sodium t-butanolate In 1,4-dioxane at 100℃; for 24h; Inert atmosphere; Overall yield = 72 %; Overall yield = 140.9 mg; |
regorafenib
A
4-(4-amino-3-fluorophenoxy)pyridine-2-carboxylic acid methyl amide
B
4-chloro-3-trifluoromethyl-aniline
Conditions | Yield |
---|---|
In water; acetonitrile at 80℃; for 72h; |
regorafenib
A
4-(4-amino-3-fluorophenoxy)pyridine-2-carboxylic acid methyl amide
B
1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(2-fluoro-4-hydroxyphenyl)urea
C
4-chloro-3-trifluoromethyl-aniline
Conditions | Yield |
---|---|
With hydrogenchloride at 80℃; for 5h; |
methanol
regorafenib
A
4-(4-amino-3-fluorophenoxy)pyridine-2-carboxylic acid methyl amide
C
4-chloro-3-trifluoromethyl-aniline
Conditions | Yield |
---|---|
With sodium hydroxide at 80℃; for 24h; |
2-chloro-1-(trifluoromethyl)phenylhydrazine
4-chloro-3-trifluoromethyl-aniline
Conditions | Yield |
---|---|
With Raney nickel In methanol for 1h; Time; Reflux; | 8.6 g |
bis(trichloromethyl) carbonate
4-chloro-3-trifluoromethyl-aniline
4-chloro-3-(trifluoromethyl)phenyl isocyanate
Conditions | Yield |
---|---|
With triethylamine In dichloromethane | 100% |
In ethyl acetate at 80℃; for 1h; | 99.2% |
In ethyl acetate at -5 - 80℃; for 3h; Solvent; | 95% |
4-chloro-3-trifluoromethyl-aniline
Conditions | Yield |
---|---|
With SHNC In water for 25h; Ambient temperature; | 99% |
chloroacetyl chloride
4-chloro-3-trifluoromethyl-aniline
[(4-chloro-3-trifluoromethylphenyl)aminocarbonylmethyl]chloride
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 0℃; Inert atmosphere; | 99% |
With pyridine In dichloromethane at 0 - 20℃; for 2h; | 98% |
With triethylamine In dichloromethane at 0℃; for 1.5h; | 84.7% |
Stage #1: chloroacetyl chloride; 4-chloro-3-trifluoromethyl-aniline With sodium hydrogencarbonate In diethyl ether; water at 20℃; for 1h; Schotten-Baumann Reaction; Stage #2: With hydrogenchloride In diethyl ether; water | |
With triethylamine In dichloromethane at 0℃; for 1.5h; |
4-chloro-3-trifluoromethyl-aniline
Conditions | Yield |
---|---|
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap In dichloromethane at 20℃; for 14h; Product distribution / selectivity; Inert atmosphere; Combinatorial reaction / High throughput screening (HTS); | 99% |
tert-Butyl 2,2,2-trichloroacetimidate
4-chloro-3-trifluoromethyl-aniline
tert-butyl(4-chloro-3-trifluoromethylphenyl)amine
Conditions | Yield |
---|---|
With copper(II) bis(trifluoromethanesulfonate) In nitromethane at 20℃; for 2h; Inert atmosphere; | 99% |
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 0 - 20℃; | 99% |
Conditions | Yield |
---|---|
With triethylamine In acetone at 90℃; for 3h; Inert atmosphere; | 99% |
Conditions | Yield |
---|---|
With potassium carbonate In water; toluene at 20℃; for 1h; Cooling with ice; | 99% |
sodium isocyanate
4-chloro-3-trifluoromethyl-aniline
4-chloro-3-trifluoromethylphenylurea
Conditions | Yield |
---|---|
With acetic acid In water at 40 - 50℃; for 2h; Temperature; | 97.2% |
With acetic acid In water at 40 - 45℃; for 1 - 2h; Product distribution / selectivity; | |
With acetic acid In water at 40 - 45℃; Product distribution / selectivity; |
4-chloro-3-trifluoromethyl-aniline
p-ethoxycarbonylphenyl isocyanate
Conditions | Yield |
---|---|
In dichloromethane | 97% |
In dichloromethane | 97% |
In dichloromethane | 97% |
In dichloromethane | 97% |
In dichloromethane at 20℃; | 97% |
tert-butyl N-({[(tert-butoxy)carbonyl]amino}methanethioyl)carbamate
4-chloro-3-trifluoromethyl-aniline
N,N′-bis(tert-butoxycarbonyl)-N′′-4-chloro-3-(trifluoromethyl)guanidine
Conditions | Yield |
---|---|
With tert.-butylhydroperoxide; iodine In water; toluene at 20℃; | 97% |
With triethylamine; copper dichloride In dichloromethane at 20℃; for 16h; | 72% |
With iodine; triethylamine In toluene at 0℃; | 65% |
4-chloro-3-trifluoromethyl-aniline
2-chloro-5-methoxyquinoline
Conditions | Yield |
---|---|
In neat (no solvent) at 160℃; | 97% |
In neat (no solvent) at 160℃; |
Conditions | Yield |
---|---|
With dmap In toluene at 55℃; Sealed tube; | 97% |
4-(4-amino-3-fluorophenoxy)pyridine-2-carboxylic acid methyl amide
Methyl 4-methyl-3-oxopentanoate
4-chloro-3-trifluoromethyl-aniline
regorafenib
Conditions | Yield |
---|---|
With dmap In N,N-dimethyl-formamide at 140℃; for 4h; Temperature; Green chemistry; | 96.8% |
4-(4-amino-3-fluorophenoxy)pyridine-2-carboxylic acid methyl amide
S,S-dimethyl dithiocarbonate
4-chloro-3-trifluoromethyl-aniline
regorafenib
Conditions | Yield |
---|---|
With tetra(n-butyl)ammonium hydroxide In tetrahydrofuran at 35℃; for 1.33333h; Green chemistry; | 96.2% |
5,7-dimethylisatin
4-chloro-3-trifluoromethyl-aniline
Conditions | Yield |
---|---|
grinding in agate mortar; | 96% |
phosphonic acid diethyl ester
4-chloro-3-trifluoromethyl-aniline
1-phenyl-3-(4-chlorophenyl)-4-pyrazolecarboxaldehyde
Conditions | Yield |
---|---|
With Porcine Pancreas Lipase In neat (no solvent) at 45℃; Enzymatic reaction; | 96% |
pivaloyl chloride
4-chloro-3-trifluoromethyl-aniline
N-(4-chloro-3-trifluoromethylphenyl)-2,2-dimethylpropionamide
Conditions | Yield |
---|---|
In triethylamine | 95% |
With triethylamine In tetrahydrofuran at 0 - 20℃; for 4h; | 60% |
In triethylamine | |
In triethylamine |
phenyl chloroformate
4-chloro-3-trifluoromethyl-aniline
(4-chloro-3-trifluoromethylphenyl)carbamic acid phenyl ester
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 5 - 20℃; for 2h; | 95% |
In dichloromethane at 20℃; for 1h; | 94% |
With pyridine In dichloromethane at 0 - 20℃; | 93.8% |
4-chloro-3-trifluoromethyl-aniline
4-azido-1-chloro-2-(trifluoromethyl)benzene
Conditions | Yield |
---|---|
Stage #1: 4-chloro-3-trifluoromethyl-aniline With hydrogenchloride In water; acetonitrile at 20℃; for 0.333333h; Stage #2: With sodium nitrite In water; acetonitrile at 20℃; for 1h; Stage #3: With sodium azide In water; acetonitrile at 0 - 20℃; for 1h; | 95% |
Stage #1: 4-chloro-3-trifluoromethyl-aniline With hydrogenchloride; sodium nitrite In ethyl acetate at 0℃; for 0.5h; Stage #2: With sodium azide In ethyl acetate at 20℃; for 2h; | 62% |
With sodium azide; sodium nitrite In acetonitrile at 0 - 5℃; for 1h; |
4-amino-phenol
urea
4-chloro-3-trifluoromethyl-aniline
4-[ ({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenol
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide at 130 - 135℃; for 3h; Temperature; | 94.8% |
phosphonic acid diethyl ester
4-chloro-3-trifluoromethyl-aniline
1,3-diphenyl-4-formylpyrazole
Conditions | Yield |
---|---|
With Porcine Pancreas Lipase In neat (no solvent) at 45℃; Enzymatic reaction; | 94% |
1-chloro-6-methyl-5-nitroisoquinoline
4-chloro-3-trifluoromethyl-aniline
Conditions | Yield |
---|---|
With trifluoroacetic acid In isopropyl alcohol at 20 - 90℃; for 18h; Inert atmosphere; | 93.3% |
difluoronitroacetyl chloride
4-chloro-3-trifluoromethyl-aniline
N-(4-Chloro-3-trifluoromethyl-phenyl)-2,2-difluoro-2-nitro-acetamide
Conditions | Yield |
---|---|
In diethyl ether at 29.9℃; for 0.5h; | 93% |
Conditions | Yield |
---|---|
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 70℃; for 20h; | 93% |
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In ethyl acetate at 0 - 5℃; for 2h; Reagent/catalyst; Solvent; | 92.5% |
Ethyl oxalyl chloride
4-chloro-3-trifluoromethyl-aniline
ethyl 2-((4-chloro-3-(trifluoromethyl)phenyl)amino)-2-oxoacetate
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; | 92% |
With N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; for 0.5h; Inert atmosphere; Schlenk technique; | 87% |
With triethylamine In dichloromethane at 20℃; |
3-chloro-3-oxopropanoic acid methyl ester
4-chloro-3-trifluoromethyl-aniline
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 0 - 20℃; | 92% |
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View