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TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

3,4-Difluoroaniline 3863-11-4 Manufacturer/High quality/Best price/In stock

Cas:3863-11-4

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

3,4-Difluoroaniline Manufacturer/High quality/Best price/In stock

Cas:3863-11-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 3,4-Difluoroaniline supplier in China

Cas:3863-11-4

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

3,4-Difluoroaniline

Cas:3863-11-4

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% 3863-11-4 3,4-Difluoroaniline Manufacturer

Cas:3863-11-4

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

3,4-Difluoroaniline

Cas:3863-11-4

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

3,4-Difluoroaniline

Cas:3863-11-4

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

1 Factory price 2 High quality 3 Good service 4 Prompt deliverychengdu and import and export trade co., LTD., who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of phar

CAS No. 3863-11-4 (3,4-Difluoroaniline )

Cas:3863-11-4

Min.Order:1 Kilogram

FOB Price: $120.0

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

3,4-Difluoroaniline Basic information Product Name: 3,4-Difluoroaniline Synonyms: TIMTEC-BB SBB007915;3,4-DIFLUOROANILINE;3,4-DIFLUOROBENZENAMINE;AKOS 91142;3,4-difluoro-benzenamin;Benzenamine, 3,4-difluo

high purity of 3,4-Difluoroaniline

Cas:3863-11-4

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Superiority As a reliable partner for Chinese market, we are specialized in chemical raw materials; consolidate sourcing, marketing, sales, distribution and after-sale services, providing our partners with sourcing evaluation, technology supports, to

3,4-Difluoroaniline 3863-11-4

Cas:3863-11-4

Min.Order:1 Gram

FOB Price: $5.0 / 15.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 3863-11-4 with best quality

Cas:3863-11-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Product name 3,4-Difluoroaniline Cas number 3863-11-4 Molecular formula C6H5F2N Molecular weight 129.11 Appearance

3,4-Difluoroaniline

Cas:3863-11-4

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:Liquid Storage:Store in sealed containers at cool & dry plac

Supply high quality cas 3863-11-4 3,4-Difluoroaniline

Cas:3863-11-4

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

3,4-Difluoroaniline 3863-11-4

Cas:3863-11-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

3,4-Difluoroaniline 99%

Cas:3863-11-4

Min.Order:1 Kilogram

FOB Price: $38.0 / 45.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

3,4-Difluoroaniline CAS:3863-11-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic interm

3,4-Difluoroaniline CAS:3863-11-4

Cas:3863-11-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

3,4-Difluoroaniline

Cas:3863-11-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:3863-11-4

Cas:3863-11-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

3,4-Difluoroaniline

Cas:3863-11-4

Min.Order:0

Negotiable

Type:Manufacturers

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Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

cas 3863-11-4 3,4-Difluoroaniline

Cas:3863-11-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

3,4-DIFLUOROANILINE

Cas:3863-11-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3,4-Difluoroaniline

Cas:3863-11-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and als

3,4-Difluoroaniline

Cas:3863-11-4

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providing h

Factory Supply 3,4-Difluoroaniline

Cas:3863-11-4

Min.Order:0

Negotiable

Type:Other

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Siwei Development Group Ltd.

Product name: 3,4-Difluoroaniline CAS No.: 3863-11-4 Molecule Formula:C6H5F2N Molecule Weight:129.11 Purity: 99.0% Package: 200kg/drum Description:Colorless or pale yellow liquid Manufacture Standards:Enterprise Standard TESTING

Lower Price 3,4-Difluoroaniline on stock

Cas:3863-11-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Shanghai Minstar Chemical Co., Ltd

3,4-Difluoroaniline Chemical Properties Melting point 22°C Boiling point 77 °C/7 mmHg (lit.) density 1.302 g/mL at 25 °C (lit.) refractive index n20/D 1.513(lit.) Fp 185 °F pka 3 +-.0.10(Predicted) Specific Grav

3,4-Difluoroaniline

Cas:3863-11-4

Min.Order:1 Gram

FOB Price: $65.0

Type:Lab/Research institutions

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Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

3,4-Difluoroaniline

Cas:3863-11-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

3,4-Difluoroaniline

Cas:3863-11-4

Min.Order:0

Negotiable

Type:Manufacturers

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SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe

SAGECHEM/3,4-Difluoroaniline

Cas:3863-11-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

3,4-Difluoroaniline

Cas:3863-11-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Synthetic route

1-tert-butyl-N-(3,4-difluorophenyl)-1,1-dimethylsilanamine
1321455-41-7

1-tert-butyl-N-(3,4-difluorophenyl)-1,1-dimethylsilanamine

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

Conditions
ConditionsYield
With silica gel In ethanol; water at 20℃; for 2h;100%
3,4-difluoronitrobenzene
369-34-6

3,4-difluoronitrobenzene

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

Conditions
ConditionsYield
With sodium tetrahydroborate; water at 0 - 20℃; for 4h;95%
With palladium on activated charcoal; hydrogen In toluene at 25 - 35℃; under 1500.15 - 4500.45 Torr; Autoclave;93.8%
With cyclohexa-1,4-diene; 5%-palladium/activated carbon In methanol at 120℃; for 0.0833333h; Microwave irradiation;82%
3,4-difluoronitrobenzene
369-34-6

3,4-difluoronitrobenzene

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

Conditions
ConditionsYield
With hydrogenchloride In methanol86%
(3,4-difluoro-phenyl)-carbamic acid benzyl ester
250372-11-3

(3,4-difluoro-phenyl)-carbamic acid benzyl ester

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

Conditions
ConditionsYield
With methanol; sodium tetrahydroborate; nickel(II) chloride hexahydrate at 20℃; for 0.25h; chemoselective reaction;83%
(3,4-difluoro-phenyl)-amide
85118-04-3

(3,4-difluoro-phenyl)-amide

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

Conditions
ConditionsYield
With potassium hydroxide; bromine In water at 0 - 88℃; for 1h;65%
4-fluoroaniline
371-40-4

4-fluoroaniline

A

2,4-difluorophenylamine
367-25-9

2,4-difluorophenylamine

B

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

Conditions
ConditionsYield
With trifluorormethanesulfonic acid; fluorine at 20℃; Title compound not separated from byproducts;
aniline
62-53-3

aniline

α-chloro-propionic acid amide

α-chloro-propionic acid amide

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: F2; TfOH / 20 °C
2: F2; TfOH / 20 °C
View Scheme
ortho-difluorobenzene
367-11-3

ortho-difluorobenzene

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: HNO3, H2SO4
2: Fe, HCl
View Scheme
4-chlorotrichloromethylbenzene
5216-25-1

4-chlorotrichloromethylbenzene

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: chlorosulfuric acid / 1) 120 deg C, 1 h 2) 150 deg C, 2 h
2: 94 percent / SOCl2 / benzene / 8 h / Heating
3: 71 percent / KF, Ph4PBr / acetonitrile / 16 h / Heating
4: 45 percent / KF, PPh4Br / tetrahydrothiophene 1,1-dioxide; toluene / 210 °C / 270 Torr
5: 82 percent / 25 aq. NH3 / H2O / 2 h
6: 65 percent / Br2, aq. KOH / H2O / 1 h / 0 - 88 °C
View Scheme
4-chloro-3-(chlorosulfonyl)benzoic acid
2494-79-3

4-chloro-3-(chlorosulfonyl)benzoic acid

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 94 percent / SOCl2 / benzene / 8 h / Heating
2: 71 percent / KF, Ph4PBr / acetonitrile / 16 h / Heating
3: 45 percent / KF, PPh4Br / tetrahydrothiophene 1,1-dioxide; toluene / 210 °C / 270 Torr
4: 82 percent / 25 aq. NH3 / H2O / 2 h
5: 65 percent / Br2, aq. KOH / H2O / 1 h / 0 - 88 °C
View Scheme
3-chlorosulfonyl-4-chlorobenzoyl chloride
62574-66-7

3-chlorosulfonyl-4-chlorobenzoyl chloride

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 71 percent / KF, Ph4PBr / acetonitrile / 16 h / Heating
2: 45 percent / KF, PPh4Br / tetrahydrothiophene 1,1-dioxide; toluene / 210 °C / 270 Torr
3: 82 percent / 25 aq. NH3 / H2O / 2 h
4: 65 percent / Br2, aq. KOH / H2O / 1 h / 0 - 88 °C
View Scheme
3,4-difluorobenzoyl fluoride
127269-25-4

3,4-difluorobenzoyl fluoride

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 82 percent / 25 aq. NH3 / H2O / 2 h
2: 65 percent / Br2, aq. KOH / H2O / 1 h / 0 - 88 °C
View Scheme
4-fluoro-3-(fluorosulfonyl)benzoyl fluoride
127986-80-5

4-fluoro-3-(fluorosulfonyl)benzoyl fluoride

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 45 percent / KF, PPh4Br / tetrahydrothiophene 1,1-dioxide; toluene / 210 °C / 270 Torr
2: 82 percent / 25 aq. NH3 / H2O / 2 h
3: 65 percent / Br2, aq. KOH / H2O / 1 h / 0 - 88 °C
View Scheme
Methyl formate
107-31-3

Methyl formate

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

3,4-di-fluorophenyl formamide
138563-55-0

3,4-di-fluorophenyl formamide

Conditions
ConditionsYield
With sodium hexamethyldisilazane In tetrahydrofuran at 0 - 20℃;100%
2-Amino-6-chloropurin
10310-21-1

2-Amino-6-chloropurin

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

N6-(3,4-difluorophenyl)-9H-purine-2,6-diamine

N6-(3,4-difluorophenyl)-9H-purine-2,6-diamine

Conditions
ConditionsYield
at 130℃; for 0.0833333h; Irradiation;100%
ethyl 3-fluoro-4-((2-(hydroxymethyl)azetidin-1-yl)sulfonyl)-1-methyl-1H-pyrrole-2-carboxylate

ethyl 3-fluoro-4-((2-(hydroxymethyl)azetidin-1-yl)sulfonyl)-1-methyl-1H-pyrrole-2-carboxylate

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

N-(3,4-difluorophenyl)-3-fluoro-4-((2-(hydroxymethyl)azetidin-1-yl)sulfonyl)-1-methyl-1H-pyrrole-2-carboxamide

N-(3,4-difluorophenyl)-3-fluoro-4-((2-(hydroxymethyl)azetidin-1-yl)sulfonyl)-1-methyl-1H-pyrrole-2-carboxamide

Conditions
ConditionsYield
With ammonium chloride; lithium hexamethyldisilazane In tetrahydrofuran; dichloromethane at 20℃;100%
acetic anhydride
108-24-7

acetic anhydride

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

3,4-difluoroacetanilide
458-11-7

3,4-difluoroacetanilide

Conditions
ConditionsYield
In 1,4-dioxane at 0℃; for 1h; Inert atmosphere; Schlenk technique;99%
at 20℃; for 0.5h;95%
With triethylamine In dichloromethane at 20℃; for 1h;91%
dimethyl acetylenedicarboxylate
762-42-5

dimethyl acetylenedicarboxylate

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

methyl 3-carbomethoxy-3-(3',4'-difluorophenyl)amino-2-propenoate
251986-50-2

methyl 3-carbomethoxy-3-(3',4'-difluorophenyl)amino-2-propenoate

Conditions
ConditionsYield
In methanol at 20℃; Addition;99%
pivaloyl chloride
3282-30-2

pivaloyl chloride

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

N-pivaloyl-3,4-difluoroaniline
205756-46-3

N-pivaloyl-3,4-difluoroaniline

Conditions
ConditionsYield
With triethylamine at 0 - 20℃; for 1h;99%
With triethylamine In benzene at 0℃;98%
With TEA In dichloromethane at 0 - 25℃; for 3h; Acylation;
With triethylamine In dichloromethane at 0 - 20℃; for 1h;
With triethylamine In toluene at 20℃;
2-chloropropionyl chloride
7623-09-8

2-chloropropionyl chloride

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

2-chloro-N-(3,4-difluoro-phenyl)-propionamide
868771-20-4

2-chloro-N-(3,4-difluoro-phenyl)-propionamide

Conditions
ConditionsYield
In toluene at 120℃; for 1h;99%
In toluene Heating;
ethyl (E)-3-(dimethylamino)acrylate
1117-37-9

ethyl (E)-3-(dimethylamino)acrylate

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

ethyl 2-[2-(3,4-difluorophenyl)hydrazinylidene]-3-oxopropanoate

ethyl 2-[2-(3,4-difluorophenyl)hydrazinylidene]-3-oxopropanoate

Conditions
ConditionsYield
Stage #1: 3,4-difluoroaniline With hydrogenchloride; sodium nitrite In water at 0℃; for 0.0833333h;
Stage #2: ethyl (E)-3-(dimethylamino)acrylate With potassium acetate In ethanol; water at 0 - 20℃; for 14h;
99%
2-chloro-5-methoxyquinoline
160893-07-2

2-chloro-5-methoxyquinoline

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

N-(3,4-difluorophenyl)-5-methoxyquinolin-2-amine

N-(3,4-difluorophenyl)-5-methoxyquinolin-2-amine

Conditions
ConditionsYield
In neat (no solvent) at 160℃;98%
In neat (no solvent) at 160℃;
1,2,3,4-tetrahydroisoquinoline
91-21-4

1,2,3,4-tetrahydroisoquinoline

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

C15H15FN2

C15H15FN2

Conditions
ConditionsYield
With silver(I) hexafluorophosphate; [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; C17H21O3P In tetrahydrofuran at 120℃; for 20h; Inert atmosphere; Molecular sieve;98%
hexamethylene imine
111-49-9

hexamethylene imine

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

C12H17FN2

C12H17FN2

Conditions
ConditionsYield
With silver(I) hexafluorophosphate; [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; C17H21O3P In tetrahydrofuran at 120℃; for 20h; Inert atmosphere; Molecular sieve;98%
With C17H21O3P; [Ru(cymene)]PF6 In tetrahydrofuran at 120℃; Molecular sieve;98%
5-(2-bromo-ethyl)-phenanthridinium bromide

5-(2-bromo-ethyl)-phenanthridinium bromide

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

1-(3,4-difluorophenyl)-1,2,3,12b-tetrahydroimidazo[1,2-f]phenanthridine
1192571-37-1

1-(3,4-difluorophenyl)-1,2,3,12b-tetrahydroimidazo[1,2-f]phenanthridine

Conditions
ConditionsYield
With triethylamine In chloroform Inert atmosphere;97.9%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

(3,4-difluorophenyl)-carbamic acid-tert-butyl ester
144298-04-4

(3,4-difluorophenyl)-carbamic acid-tert-butyl ester

Conditions
ConditionsYield
In tetrahydrofuran at 60℃; for 15h;97%
In tetrahydrofuran at 20℃; for 12h;93%
In tetrahydrofuran at 70℃; for 96h;91%
In tetrahydrofuran at 20℃; for 12h;65%
In tetrahydrofuran at 60℃; for 16h;
3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

2-iodo-4,5-difluoroaniline
847685-01-2

2-iodo-4,5-difluoroaniline

Conditions
ConditionsYield
With iodine; sodium hydrogencarbonate In water at 20℃; for 0.5h;97%
With Iodine monochloride In acetic acid at 20℃; for 0.5h;96%
With iodine; sodium hydrogencarbonate In water at 20℃; for 0.5h;92%
4-chloro-3-formylcoumarin
50329-91-4

4-chloro-3-formylcoumarin

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

6,7-difluoro-4-(2-hydroxyphenyl)quinoline-3-carboxylic acid
1394232-16-6

6,7-difluoro-4-(2-hydroxyphenyl)quinoline-3-carboxylic acid

Conditions
ConditionsYield
With sulfuric acid In methanol at 20℃; for 0.25h;97%
nitromethane
75-52-5

nitromethane

methyl 2-butoxy-6-methyl-3,4-dihydro-2H-pyran-5-carboxylate
1266617-35-9

methyl 2-butoxy-6-methyl-3,4-dihydro-2H-pyran-5-carboxylate

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

methyl 1-(3,4-difluorophenyl)-2-methyl-6-(nitromethyl)-1,4,5,6-tetrahydropyridine-3-carboxylate

methyl 1-(3,4-difluorophenyl)-2-methyl-6-(nitromethyl)-1,4,5,6-tetrahydropyridine-3-carboxylate

Conditions
ConditionsYield
With lithium bromide monohydrate at 100℃; for 11h;97%
1-Nitronaphthalene
86-57-7

1-Nitronaphthalene

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

C16H11F2N

C16H11F2N

Conditions
ConditionsYield
With bis(acetylacetonato)palladium(II); potassium phosphate tribasic trihydrate; 2-(2,6-diethyl-4-methylphenyl)-5-(2,4,6-triisopropylphenyl)imidazo[1,5-a]pyridin-2-ium chloride In 1,4-dioxane at 130℃; for 24h; Inert atmosphere;97%
4-(2,6-dichloropyrido[3,4-d]pyrimidin-4-yl)morpholine

4-(2,6-dichloropyrido[3,4-d]pyrimidin-4-yl)morpholine

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

6-chloro-N-(3,4-difluorophenyl)-4-morpholinopyrido[3,4-d]pyrimidin-2-amine

6-chloro-N-(3,4-difluorophenyl)-4-morpholinopyrido[3,4-d]pyrimidin-2-amine

Conditions
ConditionsYield
With toluene-4-sulfonic acid In iso-butanol Reflux; Inert atmosphere;96.4%
3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

4-azido-1,2-difluorobenzene
123330-51-8

4-azido-1,2-difluorobenzene

Conditions
ConditionsYield
Stage #1: 3,4-difluoroaniline With hydrogenchloride; sodium nitrite In water at 0℃; for 0.5h;
Stage #2: With sodium azide In water at 0℃; for 1h;
96.1%
Stage #1: 3,4-difluoroaniline With hydrogenchloride; sodium nitrite In water at 0℃;
Stage #2: With sodium azide In water at 0℃;
96.1%
With sodium azide; sulfuric acid; trifluoroacetic acid; sodium nitrite 1.) H2O, RT, 30 min, 2.) 1 h; Yield given. Multistep reaction;
4-chloro-3-formylcoumarin
50329-91-4

4-chloro-3-formylcoumarin

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

9,10-difluoro-6H-chromeno[4,3-b]quinolin-6-one
1357063-67-2

9,10-difluoro-6H-chromeno[4,3-b]quinolin-6-one

Conditions
ConditionsYield
In ethanol at 20℃; for 0.25h; ultrasound irradiation;96%
In methanol at 20℃; for 0.133333h; ultrasound irradiation;90%
With Amberlyst-15 In ethanol for 2h; Reflux; Inert atmosphere;81%
3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

1-(2-methylphenyl)-1,4-pentanedione
195137-30-5

1-(2-methylphenyl)-1,4-pentanedione

1-(3,4-difluorophenyl)-2-methyl-5-(2-methylphenyl)pyrrole
1445874-27-0

1-(3,4-difluorophenyl)-2-methyl-5-(2-methylphenyl)pyrrole

Conditions
ConditionsYield
With gadolinium(III) trifluoromethanesulfonate In acetonitrile at 30℃; for 0.5h; Paal-Knorr Pyrrole Synthesis;96%
ethyl acrylate
140-88-5

ethyl acrylate

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

ethyl 3-((3,4-difluorophenyl)amino)propanoate

ethyl 3-((3,4-difluorophenyl)amino)propanoate

Conditions
ConditionsYield
With trifluorormethanesulfonic acid In neat (no solvent) at 100℃; for 24h;96%
With trifluorormethanesulfonic acid at 100℃;
With trifluorormethanesulfonic acid at 100℃; for 16h; Inert atmosphere;
Propiolic acid
471-25-0

Propiolic acid

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

N-(3,4-difluorophenyl)prop-2-ynamide

N-(3,4-difluorophenyl)prop-2-ynamide

Conditions
ConditionsYield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 5℃; for 1h;96%
sodium dicyanamide
1934-75-4

sodium dicyanamide

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

1-(3,4-difluoro)phenyl-3-cyanoguanidine

1-(3,4-difluoro)phenyl-3-cyanoguanidine

Conditions
ConditionsYield
With hydrogenchloride In water at 80℃; for 1h;95.2%
With hydrogenchloride In water at 80℃; for 1h;95.2%
chloroformic acid ethyl ester
541-41-3

chloroformic acid ethyl ester

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

(3,4-difluorophenyl)carbamic acid ethyl ester
2145-85-9

(3,4-difluorophenyl)carbamic acid ethyl ester

Conditions
ConditionsYield
With pyridine In tetrahydrofuran at 20℃; for 0.5h;95%
With sodium carbonate
carbon disulfide
75-15-0

carbon disulfide

triethylamine
121-44-8

triethylamine

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

3,4-difluorophenyl dithiocarbamic acid triethylammonium
144514-15-8

3,4-difluorophenyl dithiocarbamic acid triethylammonium

Conditions
ConditionsYield
at 0℃;95%
at 0℃;
In toluene at 25 - 30℃; for 12h; Product distribution / selectivity; Cooling with ice;
3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

3,3',4,4'-tetrafluoroazobenzene

3,3',4,4'-tetrafluoroazobenzene

Conditions
ConditionsYield
With copper-manganese spinel oxide In ethyl acetate at 80℃; for 8h;95%
With potassium hydroxide; potassium hexacyanoferrate(III) In ethanol; water for 8h; Heating;65%
With potassium hydroxide; potassium hexacyanoferrate(III) In ethanol; water for 6h; Heating;60%
2-chloropropionyl chloride
625-36-5

2-chloropropionyl chloride

3,4-difluoroaniline
3863-11-4

3,4-difluoroaniline

3-chloro-N-(3,4-difluoro-phenyl)-propionamide
132669-28-4

3-chloro-N-(3,4-difluoro-phenyl)-propionamide

Conditions
ConditionsYield
With pyridine In acetone at 55℃; for 3h;95%
With triethylamine In ethyl acetate at 20 - 30℃;73%
With triethylamine In ethyl acetate at 20 - 30℃;

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