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ShangHai Soyoung Biotechnology Inc

Trade Assurance Get full protection for your orders 100% Product quality protection 100% On-time shipment protection 100% Payment protection Appearance:White or slightly yellow, crystalline powder Storage:Store in tight containers, in a cool dry p

Vinpocetine 42971-09-5

Cas:42971-09-5

Min.Order:1 Kilogram

FOB Price: $1390.0

Type:Lab/Research institutions

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Kono Chem Co.,Ltd

English Name: Vinpocetine (Calan) Molecular formula: C22H26N2O2 Molecular weight: 350.46 CAS accession number: 42971-09-5 Improve cerebral infarction sequelae, cerebral hemorrhage sequelae, cerebral arteriosclerosis and other symptoms i

Hgh quality Vinpocetine CA NO.42971-09-5 in bulk supply

Cas:42971-09-5

Min.Order:1 Kilogram

FOB Price: $800.0 / 1000.0

Type:Other

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Xi'an Yinherb Bio-Tech Co., Ltd.

Xi'an Yinherb Bio-Tech Co., Ltd was founded in 2009, We have more than 10 experienced doctors and scientists and professional managers, specializing in Nootropics, Sarms and Peptides researching and developing, and become the lead

Vinpocetine

Cas:42971-09-5

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for the fine c

Vinpocetine in stock

Cas:42971-09-5

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Sinoway Industrial Co., Ltd.

Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c

99% up GMP DMF Vinpocetine 42971-09-5

Cas:42971-09-5

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Vinpocetine supplier in China

Cas:42971-09-5

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Appearance White or slightly yellow, crystalline powder White crystalline powder olubili

High purity Various Specifications Vinpocetine CAS:42971-09-5

Cas:42971-09-5

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Manufacturers

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Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C

Vinpocetine injection 2ml/10mg;2ml/20mg

Cas:42971-09-5

Min.Order:1 Gram

Negotiable

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

Hebei yanxi chemical co., LTD is a professional research, development and production 2-phenylacetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low carbon environ

Hgh quality Vinpocetine CA NO.42971-09-5

Cas:42971-09-5

Min.Order:100 Gram

FOB Price: $2.0

Type:Manufacturers

inquiry

Wuhan Fortuna Chemical Co.,Ltd

Vinpocetine CAS 42971-09-5 Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals in distributing

Vinpocetine CAS 42971-09-5

Cas:42971-09-5

Min.Order:10 Kilogram

FOB Price: $10.0

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

T he company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality service Appearance:White

Vinpocetine

Cas:42971-09-5

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Vinpocetine

Cas:42971-09-5

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% Vinpocetine 42971-09-5 ISO Producer

Cas:42971-09-5

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Xi`an Eastling Biotech Co., Ltd.

Vinpocetine CAS: 42971-09-5;80038-06-8 Molecular Formula: C22H26N2O2 Home Product Category other other 42971-09-5 42971-09-5 - Names and Identifiers Name Vinpocetine Synonyms TCV-3B RGH 4405 RGH-4405 CAVIN

Top Quality Natural vinpocetine

Cas:42971-09-5

Min.Order:1 Kilogram

FOB Price: $35.0 / 49.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Vinpocetine

Cas:42971-09-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hubei DiBo chemical co., LTD

Name:Vinpocetine CAS:42971-09-5 Grade:For chemical industry, scientific research and export Product Quality 12 years of chemical raw materials Mature operation of the industry System stability Data storage Security without vulnerability P

Hgh quality Vinpocetine CA NO.42971-09-5 in bulk supply

Cas:42971-09-5

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Henan Tianfu Chemical Co., Ltd.

Product Name: Vinpocetine Synonyms: 3A,16A-APOVINCAMINIC ACID ETHYL ESTER;(3A,16A)-EBURNAMENINE-14-CARBOXYLIC ACID ETHYL ESTER;CAVINTON;ETHYL APOVINCAMIN-22-OATE;EBURNAMENINE;EBURNAMENINE-14-CARBOXYLIC ACID ETHYL ESTER;RGH-4405;VINPOCETIN CAS: 42

42971-09-5 Vinpocetine

Cas:42971-09-5

Min.Order:1 Kilogram

FOB Price: $230.0

Type:Lab/Research institutions

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Vinpocetine / LIDE PHARMA- Factory supply / Best price

Cas:42971-09-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be

Vinpocetine 42971-09-5

Cas:42971-09-5

Min.Order:1 Kilogram

FOB Price: $48.0 / 58.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 42971-09-5 with best quality

Cas:42971-09-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Factory supply 99% vinpocetine powder / vinpocetine in bulk cas 42971-09-5

Cas:42971-09-5

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by email in t

High purity 99% factory Vinpocetine powder in stock CAS NO.42971-09-5

Cas:42971-09-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Sinotech Import&Export Corporation

(+)-Apovincaminic acid ethyl ester; (+)-cis-Apovincaminic acid ethyl ester; 3-alpha,16-alpha-Apovincaminic acid ethyl ester; AY 27,255; Apovincaminate d'ethyle; Apovincaminate d'ethyle [French]; Apovincaminic acid ethyl ester; BRN 0900803;

Vinpocetin Tartrate

Cas:42971-09-5

Min.Order:100 Gram

FOB Price: $1.0

Type:Other

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White Crystalline Powder Storage:Store in sealed containers

HANWAYS CHEMPHARM CO.,LIMITED

Hanways chempharm is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The marketing department is located in Wuhan. We have two GMP facilities in Hubei Pr

Wholesale high quality vinpocetine powder vinpocetine CAS 42971-09-5

Cas:42971-09-5

Min.Order:1 Kilogram

FOB Price: $20.0 / 40.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Vinpocetine 42971-09-5

Cas:42971-09-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Factory Supply Smart Supplement Raw Powder Pure 99% Vinpocetine price

Cas:42971-09-5

Min.Order:10 Gram

FOB Price: $3.5

Type:Trading Company

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Leader Biochemical Group

About Product Details Items Specifications Test Results Appearance White to white crystalline powde

Manufacturer Supply Vinpocetine CAS 42971-09-5 for Scientific Research use only

Cas:42971-09-5

Min.Order:1 Gram

FOB Price: $1.0 / 5.0

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

pure 99% Periwinkle extract Powder VinpocetineCAS:42971-09-5

Cas:42971-09-5

Min.Order:10 Gram

FOB Price: $12.0 / 16.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Beluga chemical professional supply High quality vinpocetine China factory Why choose Beluga chemical 1. Beluga Chemical has a professional RESEARCH and development team and strong technical force to ensure technical support and research capabili

High quality vinpocetine China factory

Cas:42971-09-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

ethanol
64-17-5

ethanol

apovincamine
4880-92-6

apovincamine

Vinpocetine
42971-09-5

Vinpocetine

Conditions
ConditionsYield
With titanium(IV) tetraethanolate In 1,4-dioxane for 40h; Heating;92%
sodium ethanolate
141-52-6

sodium ethanolate

apovincamine
4880-92-6

apovincamine

Vinpocetine
42971-09-5

Vinpocetine

Conditions
ConditionsYield
In ethanol; toluene for 0.0166667h; Heating;90%
In ethanol for 1h; Temperature; Reflux; Autoclave; Industrial scale;1.93 kg
3-((1S,12bS)-1-Ethyl-1,2,3,4,6,7,12,12b-octahydro-indolo[2,3-a]quinolizin-1-yl)-2-[(E)-hydroxyimino]-propionic acid ethyl ester
89396-73-6

3-((1S,12bS)-1-Ethyl-1,2,3,4,6,7,12,12b-octahydro-indolo[2,3-a]quinolizin-1-yl)-2-[(E)-hydroxyimino]-propionic acid ethyl ester

Vinpocetine
42971-09-5

Vinpocetine

Conditions
ConditionsYield
In ethanol; sulfuric acid for 0.5h; Heating;83%
(1R,5S,12bS)-1-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizine-1-carbaldehyde

(1R,5S,12bS)-1-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizine-1-carbaldehyde

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

Vinpocetine
42971-09-5

Vinpocetine

Conditions
ConditionsYield
With sodium ethanolate In tetrahydrofuran at -10 - -5℃; Product distribution / selectivity;79.4%
14,15-dihydro-14β-hydroxy-(3α,16α)-eburnamenine-14-carboxylic acid ethyl ester
40163-56-2

14,15-dihydro-14β-hydroxy-(3α,16α)-eburnamenine-14-carboxylic acid ethyl ester

Vinpocetine
42971-09-5

Vinpocetine

Conditions
ConditionsYield
With methanesulfonic acid for 8h; Heating;79%
ethanol
64-17-5

ethanol

(3S,17S)-14-oxo-15-hydroxyimino-E-homoeburnane
82398-60-5

(3S,17S)-14-oxo-15-hydroxyimino-E-homoeburnane

Vinpocetine
42971-09-5

Vinpocetine

Conditions
ConditionsYield
With sulfuric acid for 5h;67.6%
(3aS,10bR,12bS)-5-Chloro-3a-ethyl-2,3,3a,4,5,11,12,12b-octahydro-1H-6,12a-diaza-indeno[7,1-cd]fluorene-5-carboxylic acid ethyl ester

(3aS,10bR,12bS)-5-Chloro-3a-ethyl-2,3,3a,4,5,11,12,12b-octahydro-1H-6,12a-diaza-indeno[7,1-cd]fluorene-5-carboxylic acid ethyl ester

Vinpocetine
42971-09-5

Vinpocetine

Conditions
ConditionsYield
In trifluoroacetic acid at 100℃; for 1h; Yield given;
ethanol
64-17-5

ethanol

vincamin
1617-90-9

vincamin

Vinpocetine
42971-09-5

Vinpocetine

Conditions
ConditionsYield
With aluminium trichloride; zinc(II) chloride 1.) reflux, 38 h, 2.) reflux, 8 h; Yield given. Multistep reaction;
vincamin
1617-90-9

vincamin

Vinpocetine
42971-09-5

Vinpocetine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 90 percent / Ti(OEt)4 / various solvent(s) / 8 h / Heating
2: 79 percent / methanesulfonic acid / 8 h / Heating
View Scheme
Multi-step reaction with 2 steps
1: 78 percent / AlCl3 / ethanol / 3 h / Heating
2: 92 percent / Ti(OEt)4 / dioxane / 40 h / Heating
View Scheme
(-)-methyl 1,2,3,4,6,7,12,12bα-octahydroindolo<2,3-a>quinolizine(1β-yl) pyruvate oxime
85588-92-7

(-)-methyl 1,2,3,4,6,7,12,12bα-octahydroindolo<2,3-a>quinolizine(1β-yl) pyruvate oxime

Vinpocetine
42971-09-5

Vinpocetine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 88 percent / p-toluenesulfonic acid monohydrate / toluene / 1.5 h / Heating
2: 90 percent / toluene; ethanol / 0.02 h / Heating
View Scheme
(-)-1β-methoxycarbonylethyl-1α-ethyl-1,2,3,4,6,7,12,12bα-octahydroindolo<2,3-a>quinolizine
23944-42-5

(-)-1β-methoxycarbonylethyl-1α-ethyl-1,2,3,4,6,7,12,12bα-octahydroindolo<2,3-a>quinolizine

Vinpocetine
42971-09-5

Vinpocetine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: tert-butyl nitrite, potassium tert-butoxide / toluene; methanol / 3 h / 40 °C
2: 88 percent / p-toluenesulfonic acid monohydrate / toluene / 1.5 h / Heating
3: 90 percent / toluene; ethanol / 0.02 h / Heating
View Scheme
Multi-step reaction with 4 steps
1: 95 percent / NaOH / aq. ethanol / 1.5 h / Heating
2: 77 percent / phosphoryl chloride / 24 h / Ambient temperature
3: tert-butyl nitrite, t-BuOK / toluene / 1 h / Ambient temperature
4: 67.6 percent / conc. H2SO4 / 5 h
View Scheme
Multi-step reaction with 3 steps
1: 60 percent / NaH / toluene / 5 h / Heating
2: tert-butyl nitrite, t-BuOK / toluene / 1 h / Ambient temperature
3: 67.6 percent / conc. H2SO4 / 5 h
View Scheme
(+)-(1α-Ethyl-1,2,3,4,6,7,12,12bα-octahydro-indolo<2,3-a>quinolizin-1β-yl)-propionic acid
83023-42-1

(+)-(1α-Ethyl-1,2,3,4,6,7,12,12bα-octahydro-indolo<2,3-a>quinolizin-1β-yl)-propionic acid

Vinpocetine
42971-09-5

Vinpocetine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 77 percent / phosphoryl chloride / 24 h / Ambient temperature
2: tert-butyl nitrite, t-BuOK / toluene / 1 h / Ambient temperature
3: 67.6 percent / conc. H2SO4 / 5 h
View Scheme
(+)-(3S,17S)-14-oxo-E-homo-eburnane
35226-41-6

(+)-(3S,17S)-14-oxo-E-homo-eburnane

Vinpocetine
42971-09-5

Vinpocetine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: tert-butyl nitrite, t-BuOK / toluene / 1 h / Ambient temperature
2: 67.6 percent / conc. H2SO4 / 5 h
View Scheme
(+/-)-1α-ethyl-1β-(2'-carboxy-2'-ethoxycarbonylethyl)-1,2,3,4,6,7,12,12bα-octahydro-indolo<2,3-a>quinolizine
77793-33-0

(+/-)-1α-ethyl-1β-(2'-carboxy-2'-ethoxycarbonylethyl)-1,2,3,4,6,7,12,12bα-octahydro-indolo<2,3-a>quinolizine

Vinpocetine
42971-09-5

Vinpocetine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 72 percent / NaNO2 / H2O; acetic acid / 1 h / Ambient temperature
2: 46.5 percent / D-dibenzoyl tartaric acid/CH2Cl2 / ethanol
3: 83 percent / ethanol; H2SO4 / 0.5 h / Heating
View Scheme
(+/-)-ethyl-(1,2,3,4,6,7,12,12bα-octahydro-indolo<2,3-a>quinolizin-1β-yl)pyruvate oxime
85647-38-7, 85647-39-8, 86194-84-5, 89396-72-5, 89396-73-6, 101978-25-0, 105221-74-7, 105221-75-8

(+/-)-ethyl-(1,2,3,4,6,7,12,12bα-octahydro-indolo<2,3-a>quinolizin-1β-yl)pyruvate oxime

Vinpocetine
42971-09-5

Vinpocetine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 46.5 percent / D-dibenzoyl tartaric acid/CH2Cl2 / ethanol
2: 83 percent / ethanol; H2SO4 / 0.5 h / Heating
View Scheme
(+/-)-1α-ethyl-1β-(2',2'-diethoxycarbonylethyl)-1,2,3,4,6,7,12,12bα-octahydro-indolo<2,3-a>quinolizine
77793-34-1, 89396-79-2, 135266-72-7

(+/-)-1α-ethyl-1β-(2',2'-diethoxycarbonylethyl)-1,2,3,4,6,7,12,12bα-octahydro-indolo<2,3-a>quinolizine

Vinpocetine
42971-09-5

Vinpocetine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 79 percent / KOH / ethanol; H2O / 4 h / Ambient temperature
2: 72 percent / NaNO2 / H2O; acetic acid / 1 h / Ambient temperature
3: 46.5 percent / D-dibenzoyl tartaric acid/CH2Cl2 / ethanol
4: 83 percent / ethanol; H2SO4 / 0.5 h / Heating
View Scheme
vincadifforminate d'ethyle
73789-07-8

vincadifforminate d'ethyle

Vinpocetine
42971-09-5

Vinpocetine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: N-chlorosuccinimide / trifluoroacetic acid / 2 h / Ambient temperature
2: trifluoroacetic acid / 1 h / 100 °C
View Scheme
sodium ethanolate
141-52-6

sodium ethanolate

vincamin
1617-90-9

vincamin

Vinpocetine
42971-09-5

Vinpocetine

Conditions
ConditionsYield
With sulfuric acid; acetic acid In ethanol at 70℃; for 3h; pH=2 - 14; Reflux; Large scale;43.2 kg
sodium ethanolate
141-52-6

sodium ethanolate

(3α,14β,16α)-14,15-dihydro-14-hydroxyeburnamenine-14-carboxylic acid
28152-73-0

(3α,14β,16α)-14,15-dihydro-14-hydroxyeburnamenine-14-carboxylic acid

Vinpocetine
42971-09-5

Vinpocetine

Conditions
ConditionsYield
With methanesulfonic acid; sulfuric acid In ethanol at 50 - 60℃; Temperature; Reagent/catalyst; Flow reactor; Large scale;
Vinpocetine
42971-09-5

Vinpocetine

Apovincaminic acid
27773-65-5

Apovincaminic acid

Conditions
ConditionsYield
With sodium hydroxide In 1,4-dioxane at 80℃; for 2h;98%
With sodium hydroxide In ethanol for 5h; Reflux;92.4%
With sodium hydroxide In methanol at 40℃; for 1h; Kinetics; Further Variations:; Reagents; Solvents; Temperatures; pH-values;
Vinpocetine
42971-09-5

Vinpocetine

(+)-apovincaminic acid N-oxide ethyl ester
109741-24-4

(+)-apovincaminic acid N-oxide ethyl ester

Conditions
ConditionsYield
With 3-chloro-benzenecarboperoxoic acid In chloroform96.1%
Vinpocetine
42971-09-5

Vinpocetine

((41S,13aS)-13a-ethyl-2,3,41,5,6,13a-hexahydro-1H-indolyl[3,2,1-de]pyridyl[3,2,1-ij][1,5]naphthyridine-12-yl)methanol
23173-26-4

((41S,13aS)-13a-ethyl-2,3,41,5,6,13a-hexahydro-1H-indolyl[3,2,1-de]pyridyl[3,2,1-ij][1,5]naphthyridine-12-yl)methanol

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 20℃; for 10h; Inert atmosphere;93%
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 20℃; for 10h;93%
With HN(CH2CH2C3H3N2Mes)2Cl2; potassium tert-butylate; hydrogen; cobalt(II) chloride In tetrahydrofuran at 100℃; under 45004.5 Torr; for 16h; Autoclave; Glovebox;78%
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 20℃; for 0.5h; Inert atmosphere;
Vinpocetine
42971-09-5

Vinpocetine

(41S,13aS)-13a-ethyl-2,3,41,5,6,13a-hexahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-hydrazide

(41S,13aS)-13a-ethyl-2,3,41,5,6,13a-hexahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-hydrazide

Conditions
ConditionsYield
With hydrazine hydrate In ethanol for 6h; Reflux;91%
Multi-step reaction with 2 steps
1.1: sodium hydroxide / 1,4-dioxane / 2 h / 80 °C
2.1: thionyl chloride / N,N-dimethyl-formamide; chloroform / 3 h / 0 °C / Reflux
2.2: 2 h / 20 °C
View Scheme
Vinpocetine
42971-09-5

Vinpocetine

recorcinol
108-46-3

recorcinol

C22H26N2O2*C6H6O2

C22H26N2O2*C6H6O2

Conditions
ConditionsYield
In 5,5-dimethyl-1,3-cyclohexadiene at 0 - 120℃; for 17h; Solvent; Temperature;91%
Vinpocetine
42971-09-5

Vinpocetine

2,7-seco vinpocetine
1415983-13-9

2,7-seco vinpocetine

Conditions
ConditionsYield
With 3,7-bis(dimethylamino)phenothiazin-5-ium chloride trihydrate; oxygen In methanol Irradiation;74%
Vinpocetine
42971-09-5

Vinpocetine

vinpocetine hydrochloride

vinpocetine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In ethanol; cyclohexane at 20℃; for 2h; Solvent;74%
With hydrogenchloride In ethanol; water; toluene
nicotinamide oxime
1594-58-7

nicotinamide oxime

Vinpocetine
42971-09-5

Vinpocetine

C26H25N5O

C26H25N5O

Conditions
ConditionsYield
With sodium ethanolate In ethanol for 10h; Reflux;72%
Vinpocetine
42971-09-5

Vinpocetine

(+)-15α-Chloro-vincaminic acid ethyl ester
142892-65-7

(+)-15α-Chloro-vincaminic acid ethyl ester

Conditions
ConditionsYield
With hydrogenchloride; sodium nitrite In water at 10 - 15℃; for 0.333333h;55%
Vinpocetine
42971-09-5

Vinpocetine

A

(+)-vinpocetine-10-sulfonyl chloride
198214-30-1

(+)-vinpocetine-10-sulfonyl chloride

B

(+)-vinpocetine-11-sulfonyl chloride

(+)-vinpocetine-11-sulfonyl chloride

Conditions
ConditionsYield
With chlorosulfonic acid In chloroform for 0.5h; Ambient temperature;A 43.7%
B 6.2%
Vinpocetine
42971-09-5

Vinpocetine

A

11-nitro-apovincaminic acid ethyl ester

11-nitro-apovincaminic acid ethyl ester

B

9-nitro-apovincaminic acid ethyl ester

9-nitro-apovincaminic acid ethyl ester

C

(-)-2,7-dihydro-7α,10-dinitro-2α-hydroxy-eburnamenine(3α,16α)-14-carboxylic acid ethyl ester

(-)-2,7-dihydro-7α,10-dinitro-2α-hydroxy-eburnamenine(3α,16α)-14-carboxylic acid ethyl ester

Conditions
ConditionsYield
With nitric acid In acetic acid for 0.5h; Ambient temperature;A n/a
B n/a
C 10%
Vinpocetine
42971-09-5

Vinpocetine

A

Apovincaminic acid
27773-65-5

Apovincaminic acid

B

14,15-dihydro-14β-hydroxy-(3α,16α)-eburnamenine-14-carboxylic acid ethyl ester
40163-56-2

14,15-dihydro-14β-hydroxy-(3α,16α)-eburnamenine-14-carboxylic acid ethyl ester

C

3α-epivincaminic acid ethyl ester

3α-epivincaminic acid ethyl ester

D

14-epivincaminic acid

14-epivincaminic acid

E

vinburnine
4880-88-0

vinburnine

F

(3α,14β,16α)-14,15-dihydro-14-hydroxyeburnamenine-14-carboxylic acid
28152-73-0

(3α,14β,16α)-14,15-dihydro-14-hydroxyeburnamenine-14-carboxylic acid

Conditions
ConditionsYield
With hydrogenchloride at 80℃; for 336h; Product distribution; Rate constant; Thermodynamic data; ln A, Ea, ΔS<*>; degradation of vinpocetine in aqueous solutions, degradation products equilibria in solutions, effect of various pH, temperature and ionic strength, buffer catalysis, metal ion catalysis, oxygen effect, mechanism;
Vinpocetine
42971-09-5

Vinpocetine

A

3α-deoxyvincaminic acid ethyl ester
57327-92-1

3α-deoxyvincaminic acid ethyl ester

B

3α-deoxyepivincaminic acid ethyl ester
57517-54-1

3α-deoxyepivincaminic acid ethyl ester

Conditions
ConditionsYield
With hydrogen; Rh on carbon In methanol at 25℃; under 4500.4 Torr; Yield given. Yields of byproduct given;
With hydrogen; palladium on activated charcoal In methanol at 25℃; under 4500.4 Torr; Yield given. Yields of byproduct given;
tryptamine
61-54-1

tryptamine

Vinpocetine
42971-09-5

Vinpocetine

A

(11aS,11bS)-11a-Ethyl-8-[2-(1H-indol-3-yl)-ethylsulfamoyl]-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

(11aS,11bS)-11a-Ethyl-8-[2-(1H-indol-3-yl)-ethylsulfamoyl]-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

B

(11aS,11bS)-11a-Ethyl-7-[2-(1H-indol-3-yl)-ethylsulfamoyl]-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

(11aS,11bS)-11a-Ethyl-7-[2-(1H-indol-3-yl)-ethylsulfamoyl]-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

Conditions
ConditionsYield
With chlorosulfonic acid 1) CHCl3, r.t., 0.5 h, 2) CHCl3, r.t.; Yield given. Multistep reaction;
cyclohexylamine
108-91-8

cyclohexylamine

Vinpocetine
42971-09-5

Vinpocetine

A

(11aS,11bS)-8-Cyclohexylsulfamoyl-11a-ethyl-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

(11aS,11bS)-8-Cyclohexylsulfamoyl-11a-ethyl-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

B

(11aS,11bS)-7-Cyclohexylsulfamoyl-11a-ethyl-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

(11aS,11bS)-7-Cyclohexylsulfamoyl-11a-ethyl-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

Conditions
ConditionsYield
With chlorosulfonic acid 1) CHCl3, r.t., 0.5 h, 2) CHCl3, r.t.; Yield given. Multistep reaction;
4-methoxy-aniline
104-94-9

4-methoxy-aniline

Vinpocetine
42971-09-5

Vinpocetine

A

(11aS,11bS)-11a-Ethyl-8-(4-methoxy-phenylsulfamoyl)-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

(11aS,11bS)-11a-Ethyl-8-(4-methoxy-phenylsulfamoyl)-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

B

(11aS,11bS)-11a-Ethyl-7-(4-methoxy-phenylsulfamoyl)-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

(11aS,11bS)-11a-Ethyl-7-(4-methoxy-phenylsulfamoyl)-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

Conditions
ConditionsYield
With chlorosulfonic acid 1) CHCl3, r.t., 0.5 h, 2) CHCl3, r.t.; Yield given. Multistep reaction;
4-Methoxyphenethylamine
55-81-2

4-Methoxyphenethylamine

Vinpocetine
42971-09-5

Vinpocetine

A

(11aS,11bS)-11a-Ethyl-8-[2-(4-methoxy-phenyl)-ethylsulfamoyl]-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

(11aS,11bS)-11a-Ethyl-8-[2-(4-methoxy-phenyl)-ethylsulfamoyl]-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

B

(11aS,11bS)-11a-Ethyl-7-[2-(4-methoxy-phenyl)-ethylsulfamoyl]-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

(11aS,11bS)-11a-Ethyl-7-[2-(4-methoxy-phenyl)-ethylsulfamoyl]-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

Conditions
ConditionsYield
With chlorosulfonic acid 1) CHCl3, r.t., 0.5 h, 2) CHCl3, r.t.; Yield given. Multistep reaction;
N-butylamine
109-73-9

N-butylamine

Vinpocetine
42971-09-5

Vinpocetine

A

(11aS,11bS)-8-Butylsulfamoyl-11a-ethyl-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

(11aS,11bS)-8-Butylsulfamoyl-11a-ethyl-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

B

(11aS,11bS)-7-Butylsulfamoyl-11a-ethyl-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

(11aS,11bS)-7-Butylsulfamoyl-11a-ethyl-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

Conditions
ConditionsYield
With chlorosulfonic acid 1) CHCl3, r.t., 0.5 h, 2) CHCl3, r.t.; Yield given. Multistep reaction;
benzylamine
100-46-9

benzylamine

Vinpocetine
42971-09-5

Vinpocetine

A

(11aS,11bS)-8-Benzylsulfamoyl-11a-ethyl-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

(11aS,11bS)-8-Benzylsulfamoyl-11a-ethyl-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

B

(11aS,11bS)-7-Benzylsulfamoyl-11a-ethyl-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

(11aS,11bS)-7-Benzylsulfamoyl-11a-ethyl-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

Conditions
ConditionsYield
With chlorosulfonic acid 1) CHCl3, r.t., 0.5 h, 2) CHCl3, r.t.; Yield given. Multistep reaction;
4-Aminobenzonitrile
873-74-5

4-Aminobenzonitrile

Vinpocetine
42971-09-5

Vinpocetine

A

(11aS,11bS)-8-(4-Cyano-phenylsulfamoyl)-11a-ethyl-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

(11aS,11bS)-8-(4-Cyano-phenylsulfamoyl)-11a-ethyl-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

B

(11aS,11bS)-7-(4-Cyano-phenylsulfamoyl)-11a-ethyl-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

(11aS,11bS)-7-(4-Cyano-phenylsulfamoyl)-11a-ethyl-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

Conditions
ConditionsYield
With chlorosulfonic acid 1) CHCl3, r.t., 0.5 h, 2) CHCl3, r.t.; Yield given. Multistep reaction;
o-methoxy-2-phenylethylamine
2045-79-6

o-methoxy-2-phenylethylamine

Vinpocetine
42971-09-5

Vinpocetine

A

(11aS,11bS)-11a-Ethyl-8-[2-(2-methoxy-phenyl)-ethylsulfamoyl]-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

(11aS,11bS)-11a-Ethyl-8-[2-(2-methoxy-phenyl)-ethylsulfamoyl]-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

B

(11aS,11bS)-11a-Ethyl-7-[2-(2-methoxy-phenyl)-ethylsulfamoyl]-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

(11aS,11bS)-11a-Ethyl-7-[2-(2-methoxy-phenyl)-ethylsulfamoyl]-2,3,4,5,11a,11b-hexahydro-1H-3a,9b-diaza-benzo[cd]fluoranthene-10-carboxylic acid ethyl ester

Conditions
ConditionsYield
With chlorosulfonic acid 1) CHCl3, r.t., 0.5 h, 2) CHCl3, r.t.; Yield given. Multistep reaction;
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