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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

4-Fluorobenzyl alcohol Manufacturer/High quality/Best price/In stock

Cas:459-56-3

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 4-fluorobenzyl alcohol supplier in China

Cas:459-56-3

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

4-Fluorobenzyl alcohol

Cas:459-56-3

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our advantage:Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scient

TIANFU-CHEM 4-Fluorobenzyl alcohol

Cas:459-56-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

4-Fluorobenzyl alcohol

Cas:459-56-3

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Wholesale price CAS 459-56-3 with best price

Cas:459-56-3

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

Benzenemethanol,4-fluoro-

Cas:459-56-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Benzenemethanol,4-fluoro-

Cas:459-56-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

4-fluorobenzyl alcohol CAS459-56-3

Cas:459-56-3

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

4-Fluorobenzyl alcohol

Cas:459-56-3

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

4-Fluorobenzyl alcohol

Cas:459-56-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

4-Fluorobenzyl alcohol

Cas:459-56-3

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 4-fluorobenzyl alcohol

Cas:459-56-3

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

4-fluorobenzyl alcohol

Cas:459-56-3

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

Henan Sinotech Import&Export Corporation

Chemical Names: 4-Fluorobenzyl alcohol Chemical Structure: Molecular Formula: C7H7O CAS: 459-56-3 Properties: Colorle

4-Fluorobenzyl alcohol

Cas:459-56-3

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Shanghai Minstar Chemical Co., Ltd

4-Fluorobenzyl alcohol Chemical Properties Melting point 23°C Boiling point 204-206 °C density 1.156 g/mL at 25 °C(lit.) refractive index n20/D 1.507(lit.) Fp 194 °F storage temp. Store below +30°C. pka

4-Fluorobenzyl Alcohol

Cas:459-56-3

Min.Order:1 Gram

FOB Price: $65.0

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

4-fluorobenzyl alcohol

Cas:459-56-3

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

4-Fluorobenzyl alcohol

Cas:459-56-3

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

4-fluorobenzyl alcohol

Cas:459-56-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

4-fluorobenzyl alcohol

Cas:459-56-3

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

4-Fluorobenzoic alcohol

Cas:459-56-3

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Wuhan Fortuna Chemical Co.,Ltd

1.Product name:4-Fluorobenzyl alcohol 2.CAS:459-56-3 3.MF:C6H4FNO2 4.Appearance:White crystalline powder 5.Assay:99%MIN Appearance:white powder Storage:Available Package:25KG Or as client requirement Application:Important pharm interm

4-Fluorobenzyl alcohol CAS 459-56-3

Cas:459-56-3

Min.Order:0 Metric Ton

Negotiable

Type:Trading Company

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

4-fluorobenzyl alcohol

Cas:459-56-3

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:colorless transparent liquid Storage:stored in a cool, dry and ventilated place to provent sun and rain Package:25kg/drum, or as per your request. Application:Used in organic syn

4-Fluorobenzyl alcohol

Cas:459-56-3

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

4-fluorobenzyl alcohol

Cas:459-56-3

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, in

4-Fluorobenzyl alcohol

Cas:459-56-3

Min.Order:1 Kilogram

FOB Price: $5.0 / 10.0

Type:Lab/Research institutions

inquiry

Changzhou Anchor Biological Technology Co., Ltd.

Our company is engaged in customizing the benzene ring and pyridine derivative organic intermediates, and the quantity is flexible according to customer's needs. It mainly provides high-quality intermediates for domestic and foreign pharmaceutical an

(4-Fluorophenyl)methanol Manufacturer/High quality/Best price/In stock CAS NO.459-56-3

Cas:459-56-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratoryAppearance:White or light yellow solid to liquid Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

4-Fluorobenzyl alcohol cas no. 459-56-3 98%+%

Cas:459-56-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

4-fluorobenzyl alcohol

Cas:459-56-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

4-fluorobenzyl alcohol

Cas:459-56-3

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

4-Fluorobenzoic acid
456-22-4

4-Fluorobenzoic acid

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran at 20℃; Inert atmosphere; Cooling with ice;100%
Stage #1: 4-Fluorobenzoic acid With 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane at 20℃; for 12h; Inert atmosphere;
Stage #2: With silica gel In methanol at 50℃; for 3h;
90%
With cobalt(II) tetrafluoroborate hexahydrate; hydrogen; [2-((diphenylphospino)methyl)-2-methyl-1,3-propanediyl]bis[diphenylphosphine] In tetrahydrofuran at 100℃; under 60006 Torr; for 22h;84%
4-fluorobenzaldehyde
459-57-4

4-fluorobenzaldehyde

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

Conditions
ConditionsYield
With sodium tetrahydroborate In methanol at 20℃; for 1h;100%
With C24H30Cl2NPRuS2; potassium tert-butylate; hydrogen In dichloromethane; toluene at 80℃; under 15001.5 Torr; for 5h; Autoclave;100%
With C55H44O2P4Ru; hydrogen In toluene at 80℃; under 38002.6 Torr; for 18h; Glovebox; Autoclave;99%
p-fluorotoluene
352-32-9

p-fluorotoluene

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

Conditions
ConditionsYield
With cerium(IV) triflate; water at 20℃; for 25h;100%
With sodium anthraquinone-2-sulfonate; oxygen In water at 30℃; Irradiation;
p-fluorobenzyl acetate
502-00-1

p-fluorobenzyl acetate

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

Conditions
ConditionsYield
With methanol; potassium permanganate at 25℃; chemoselective reaction;99%
With water In acetonitrile for 0.166667h; Quantum yield; Irradiation;
methyl 4-flurobenzoate
403-33-8

methyl 4-flurobenzoate

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

Conditions
ConditionsYield
With C23H29Cl2N2OPRuS; potassium tert-butylate; hydrogen In 2-methyltetrahydrofuran at 100℃; under 37503.8 Torr; for 16h; Catalytic behavior; Time; Autoclave;99%
With C27H35Cl2N2OPRuS; potassium tert-butylate; hydrogen In 2-methyltetrahydrofuran at 100℃; under 37503.8 Torr; for 2h; Catalytic behavior; Time; Autoclave;99%
With C27H34Cl2NO2PRuS; potassium tert-butylate; hydrogen In 2-methyltetrahydrofuran at 100℃; under 37503.8 Torr; for 16h; Catalytic behavior; Time; Autoclave;98%
2-((4-fluorobenzyl)oxy)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

2-((4-fluorobenzyl)oxy)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

Conditions
ConditionsYield
With silica gel In ethyl acetate; Petroleum ether99%
With silica gel In methanol at 60℃; for 3h; Inert atmosphere;92%
In methanol at 20℃; for 1h; Inert atmosphere; Glovebox;92%
4-fluorobenzyl trifluoroacetate
139058-95-0

4-fluorobenzyl trifluoroacetate

A

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

B

2,2,2-trifluoroethanol
75-89-8

2,2,2-trifluoroethanol

Conditions
ConditionsYield
With trans-[(2,6-bis(di-tert-butylphosphinomethyl)pyridine)Fe(H)2(CO)]; hydrogen; sodium methylate In 1,4-dioxane at 40℃; under 18751.9 Torr; for 16h; Glovebox; Inert atmosphere;A n/a
B 97%
With trimethylamine-N-oxide; tricarbonyl(η4-1,3-bis(trimethylsilyl)-4,5,6,7-tetrahydro-2H-inden-2-one)iron; hydrogen; triethylamine In toluene at 90℃; under 52505.3 Torr; for 17h; Inert atmosphere; Glovebox;
C13H13FOSi

C13H13FOSi

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

Conditions
ConditionsYield
With sodium hydroxide In water Schlenk technique; Inert atmosphere;97%
With sodium hydroxide In water
(4-fluorobenzyloxy)trimethylsilane
14629-55-1

(4-fluorobenzyloxy)trimethylsilane

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

Conditions
ConditionsYield
With 1-butyl-3-methylimidazolium chloride at 20℃; for 0.66h;95%
With 1,4-diazabicyclo[2.2.2]octane tribromide supported on magnetic Fe3O4 nanoparticles In methanol at 20℃; for 0.0833333h;90%
4-fluoro-3-nitrobenzaldehyde
42564-51-2

4-fluoro-3-nitrobenzaldehyde

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

Conditions
ConditionsYield
With sodium tetrahydroborate In methanol95%
1-chloromethyl-4-fluorobenzene
352-11-4

1-chloromethyl-4-fluorobenzene

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

Conditions
ConditionsYield
With iron(III) sulfate; water In toluene at 110℃; for 3h; Ionic liquid;93%
With water; sodium carbonate
With sodium carbonate for 6h; Heating; Yield given;
4-fluoro-N,N-diphenylbenzamide
79606-49-8

4-fluoro-N,N-diphenylbenzamide

A

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

B

diphenylamine
122-39-4

diphenylamine

Conditions
ConditionsYield
With potassium phosphate; C29H55FeNOP2; hydrogen In tetrahydrofuran at 130℃; under 37503.8 Torr; for 3h; Catalytic behavior;A n/a
B 93%
4-fluorobenzaldehyde
459-57-4

4-fluorobenzaldehyde

A

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

B

tris(4-fluorobenzyl)amine
932724-63-5

tris(4-fluorobenzyl)amine

C

para-fluorobenzylamine
140-75-0

para-fluorobenzylamine

D

benzylamine
100-46-9

benzylamine

E

1-(4-fluorophenyl)-N-[(4-fluorophenyl)methyl]methanamine
134227-41-1

1-(4-fluorophenyl)-N-[(4-fluorophenyl)methyl]methanamine

Conditions
ConditionsYield
With ammonia; hydrogen; Ni/C catalyst In water at 120℃; under 28502.9 - 33753.4 Torr; for 17.5h;A 1.2%
B 1.4%
C 90.7%
D 0.4%
E 1.8%
4-fluorobenzoic acid ethyl ester
451-46-7

4-fluorobenzoic acid ethyl ester

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

Conditions
ConditionsYield
With C33H29FeMnN2O3P; hydrogen; potassium carbonate In ethanol at 90℃; under 37503.8 Torr; for 16h; Catalytic behavior; Solvent; Pressure; Autoclave;90%
With [(Rc,Sp)-N-2-picoIynyI-1-(-2-bis(4-methoxy-3,5-dimethlphenyl)phosphino)ferrocenylethylamine]-kN1-kN2-kP-tricarbonylmanganese(I) bromide; hydrogen; potassium carbonate In ethanol at 90℃; Solvent; Reagent/catalyst; Temperature; Autoclave;90%
With potassium tert-butylate; C39H41FeMnN2O5P(1+)*Br(1-); 1-Methylnaphthalene In ethanol at 100℃; for 22h; Temperature; Inert atmosphere; Schlenk technique; Darkness;77%
Multi-step reaction with 2 steps
1: lithium tert-butoxide / tetrahydrofuran / 0 - 20 °C
2: sodium hydroxide / water / 1 h / 20 °C
View Scheme
With C41H46FeMnN3O5P(1+)*Br(1-); hydrogen; potassium carbonate In ethanol at 70℃; under 15001.5 Torr; for 5h; Catalytic behavior; Reagent/catalyst; Temperature;43.3 %Spectr.
4-Fluorobenzyl bromide
459-46-1

4-Fluorobenzyl bromide

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

Conditions
ConditionsYield
With water In dimethyl sulfoxide at 50℃; for 24h; Schlenk technique;87%
With water; dimethyl sulfoxide at 50℃; for 24h; Schlenk technique; Sealed tube;87%
With water; potassium carbonate
4-fluorobenzaldehyde
459-57-4

4-fluorobenzaldehyde

A

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

B

4-Fluorobenzoic acid
456-22-4

4-Fluorobenzoic acid

Conditions
ConditionsYield
With sodium hydroxide In water at 25℃; for 3.5h; Cannizzaro Reaction;A n/a
B 86%
With potassium hydroxide
With barium dihydroxide; formaldehyd at 100 - 110℃; for 0.2h;A 88 % Chromat.
B 11 % Chromat.
Stage #1: 4-fluorobenzaldehyde In neat (no solvent) for 0.0333333h; Green chemistry;
Stage #2: With 1,4-diaza-bicyclo[2.2.2]octane In neat (no solvent) at 40℃; for 0.00416667h; Reagent/catalyst; Cannizzaro Reaction; Microwave irradiation; Green chemistry;
tributyl[4-(hydroxymethyl)phenyl]tin

tributyl[4-(hydroxymethyl)phenyl]tin

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

Conditions
ConditionsYield
With methanol; sodium triflate; sodium hydrogencarbonate; 1-(chloromethyl)-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(hexafluorophosphate); silver(l) oxide In acetone at 65℃; for 4h; Sealed vial; Inert atmosphere;80%
With copper(II) bis(trifluoromethanesulfonate); tetrabutylammonium triphenyldifluorosilicate In acetonitrile at 23 - 60℃; for 3h; Sealed tube; regiospecific reaction;60%
4-fluorobenzaldehyde p-toluenesulfonylhydrazone
210422-66-5

4-fluorobenzaldehyde p-toluenesulfonylhydrazone

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

Conditions
ConditionsYield
With water; potassium carbonate at 130℃; for 0.166667h; Microwave irradiation;80%
4-fluoro-1-iodobenzene
352-34-1

4-fluoro-1-iodobenzene

carbon dioxide
124-38-9

carbon dioxide

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

Conditions
ConditionsYield
With methyldiphenylsilane; palladium on activated charcoal In water; acetonitrile at 80℃; under 7500.75 Torr; for 9h;80%
2-(4-fluorophenyl)-1,3-oxathiolane

2-(4-fluorophenyl)-1,3-oxathiolane

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

Conditions
ConditionsYield
With methanol; sodium tetrahydroborate; nickel(II) chloride hexahydrate at 20℃; for 2h;80%
(±)-2-[(4-fluorobenzyl)oxy]tetrahydropyran
18539-44-1

(±)-2-[(4-fluorobenzyl)oxy]tetrahydropyran

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

Conditions
ConditionsYield
With 1,4-diazabicyclo[2.2.2]octane tribromide supported on magnetic Fe3O4 nanoparticles In methanol at 20℃;80%
lithium pyrrolide
20671-52-7

lithium pyrrolide

4-fluorobenzaldehyde
459-57-4

4-fluorobenzaldehyde

A

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

B

(4-fluorophenyl)(1H-pyrrol-2-yl)methanone
13169-73-8

(4-fluorophenyl)(1H-pyrrol-2-yl)methanone

C

1-(4-fluorophenyl)pentan-1-ol
3913-55-1

1-(4-fluorophenyl)pentan-1-ol

Conditions
ConditionsYield
Stage #1: lithium pyrrolide With zirconium(IV) chloride In tetrahydrofuran; cyclohexane at -78℃; for 0.333333h; Inert atmosphere;
Stage #2: With n-butyllithium In tetrahydrofuran; cyclohexane at -78 - 20℃; Inert atmosphere;
Stage #3: 4-fluorobenzaldehyde In tetrahydrofuran; cyclohexane at 20℃; for 48h; Inert atmosphere;
A 13%
B 8%
C 79%
Pd(C5H5N)(C13H8N2SO2C6H4NO2)(C6H4CH2OH)
1063716-63-1

Pd(C5H5N)(C13H8N2SO2C6H4NO2)(C6H4CH2OH)

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

Conditions
ConditionsYield
With Selectfluor In acetonitrile at 50℃; for 0.5h; Product distribution / selectivity;78%
N,N-dimethyl-4-fluorobenzamide
24167-56-4

N,N-dimethyl-4-fluorobenzamide

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

Conditions
ConditionsYield
With sodium hydride; sodium iodide; zinc(II) iodide In tetrahydrofuran; mineral oil at 40℃; for 7h; Sealed tube;76%
4-fluorobenzaldehyde
459-57-4

4-fluorobenzaldehyde

A

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

B

2,2-bis(4-fluorophenyl)ethanol

2,2-bis(4-fluorophenyl)ethanol

Conditions
ConditionsYield
With zinc In water at 90 - 160℃; for 2h; Microwave irradiation; Green chemistry;A 13%
B 75%
p-Fluorophenylacetic acid
405-50-5

p-Fluorophenylacetic acid

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

Conditions
ConditionsYield
With sodium tetrahydroborate; [4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-N1,N1′]bis{3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-κN]phenyl-κC}iridium(III) hexafluorophosphate; oxygen; caesium carbonate In dichloromethane at 40℃; for 40h; Irradiation;75%
p-fluorobenzamide
824-75-9

p-fluorobenzamide

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

Conditions
ConditionsYield
With C24H20ClN2OPRu; potassium tert-butylate; hydrogen In tetrahydrofuran at 110℃; under 10640.7 Torr; for 36h; Inert atmosphere; Schlenk technique;73%
4-fluorobenzaldehyde
459-57-4

4-fluorobenzaldehyde

dibenzylamine
103-49-1

dibenzylamine

A

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

B

N,N-dibenzyl-1-(4-fluorophenyl)methanamine
359445-99-1

N,N-dibenzyl-1-(4-fluorophenyl)methanamine

Conditions
ConditionsYield
With sodium tetrahydroborate; carbon dioxide In tetrahydrofuran at 20℃; Solvent;A 27%
B 72%
With sodium tetrahydroborate; carbon dioxide In 1,4-dioxane at 20℃; Solvent; Reagent/catalyst;A 54%
B 35%
4-fluorobenzaldehyde
459-57-4

4-fluorobenzaldehyde

A

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

B

1,2-bis(4-fluorophenyl)-1,2-ethanediol
24133-58-2

1,2-bis(4-fluorophenyl)-1,2-ethanediol

Conditions
ConditionsYield
With triethylamine; 2-hydroxyethanethiol In acetonitrile for 23h; Irradiation;A 70%
B 18%
With lithium sulfate; sulfuric acid; trilithium citrate; lithium chloride In methanol; water Product distribution; Mechanism; Ambient temperature; electrolysis in membrane flow cell with Pb cathode at several pH and cathode potential;
With lithium sulfate; sulfuric acid; trilithium citrate; lithium chloride In methanol; water Ambient temperature; electrolysis in membrane flow cell with a Pb cathode;
4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

4-Fluorobenzyl bromide
459-46-1

4-Fluorobenzyl bromide

Conditions
ConditionsYield
With phosphorus tribromide In benzene at 20℃;100%
With 1,1,1,2,2,2-hexamethyldisilane In chloroform for 2.5h; Reflux;98%
With trimethylsilyl bromide In neat (no solvent) at 20℃; for 18h; Green chemistry; chemoselective reaction;98%
4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

4-fluorobenzaldehyde
459-57-4

4-fluorobenzaldehyde

Conditions
ConditionsYield
With oxygen; perruthenate modified mesoporous silicate MCM-41 In toluene at 80℃; for 1h; Oxidation;100%
With 2,2,6,6-tetramethyl-piperidine-N-oxyl; oxygen; copper(I) bromide dimethylsulfide complex In chlorobenzene at 90℃; for 6h;100%
With iron(III) chloride; 4-acetylamino-2,2,6,6-tetramethyl-1-piperidinoxy; oxygen; sodium nitrite In 1,2-dichloro-ethane at 50℃; under 3000.3 Torr; for 5h; Autoclave;99%
4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

1-(tert-butyldimethylsilyloxymethyl)-4-fluorobenzene
113984-76-2

1-(tert-butyldimethylsilyloxymethyl)-4-fluorobenzene

Conditions
ConditionsYield
With 1H-imidazole In tetrahydrofuran at 25℃;100%
With 1H-imidazole In N,N-dimethyl-formamide at 0 - 20℃; for 18h;99%
With 1H-imidazole In N,N-dimethyl-formamide at 0 - 20℃; for 18h;99%
4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

4-Fluorobenzoic acid
456-22-4

4-Fluorobenzoic acid

Conditions
ConditionsYield
With sodium hypochlorite; sodium hydrogencarbonate for 1.33333h;100%
With diethylene glycol dimethyl ether at 70℃; for 0.5h; Sonication;97%
With oxygen at 120℃; for 10h; Green chemistry;95%
4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

acetic anhydride
108-24-7

acetic anhydride

p-fluorobenzyl acetate
502-00-1

p-fluorobenzyl acetate

Conditions
ConditionsYield
With thalium(III) chloride tetrahydrate at 20℃; for 0.0666667h;99%
With polyvinylpolypyrrolidone-bound boron trifluoride In acetonitrile at 20℃; for 2h;99%
With tribromomelamine In dichloromethane at 20℃; for 0.833333h; Green chemistry; chemoselective reaction;99%
4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

tert-butyl(4-fluorobenzyl)dimethylsilane

tert-butyl(4-fluorobenzyl)dimethylsilane

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide at 0 - 20℃; for 18h;99%
4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

4-fluorobenzonitrile
1194-02-1

4-fluorobenzonitrile

Conditions
ConditionsYield
Stage #1: 4-fluorobenzylic alcohol With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; iodine In dichloromethane at 20℃; for 1h; Inert atmosphere;
Stage #2: With ammonia; iodine In dichloromethane; water at 20℃; for 2h; Inert atmosphere;
99%
Stage #1: 4-fluorobenzylic alcohol With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; iodine In dichloromethane at 20℃; for 1h;
Stage #2: With ammonium hydroxide In dichloromethane at 20℃; for 2h; Reagent/catalyst;
99%
With ammonia; oxygen In tert-Amyl alcohol; water at 100℃; under 3750.38 Torr; for 5h; Autoclave; High pressure;99%
4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

cis-Octadecenoic acid
112-80-1

cis-Octadecenoic acid

p-fluorobenzyl oleate

p-fluorobenzyl oleate

Conditions
ConditionsYield
at 75℃;99%
4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

2-amino-benzenethiol
137-07-5

2-amino-benzenethiol

2-(4-fluorophenyl)-benzothiazole
1629-26-1

2-(4-fluorophenyl)-benzothiazole

Conditions
ConditionsYield
With potassium tert-butylate In toluene at 20 - 110℃; for 48h;99%
With C15H20MnN2O3S(1+)*Br(1-); potassium hydroxide In neat (no solvent) at 140℃; Inert atmosphere; Green chemistry;76%
With sodium t-butanolate In toluene at 120℃; for 24h; Schlenk technique; Sealed tube; Green chemistry;37%
carbon disulfide
75-15-0

carbon disulfide

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

C8H6FOS2(1-)*K(1+)

C8H6FOS2(1-)*K(1+)

Conditions
ConditionsYield
With potassium hydroxide In diethyl ether at 20℃; for 12h;99%
9H-fluorene
86-73-7

9H-fluorene

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

9-(4-fluorobenzyl)-9H-fluorene

9-(4-fluorobenzyl)-9H-fluorene

Conditions
ConditionsYield
With potassium tert-butylate In toluene at 120℃; for 3h; Inert atmosphere;99%
With [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; potassium tert-butylate In toluene at 120℃; for 18h; Inert atmosphere; Sealed tube;90%
4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

1,1,1,3,3,3-hexamethyl-disilazane
999-97-3

1,1,1,3,3,3-hexamethyl-disilazane

(4-fluorobenzyloxy)trimethylsilane
14629-55-1

(4-fluorobenzyloxy)trimethylsilane

Conditions
ConditionsYield
With Nafion SAC-13 at 20℃; for 0.0666667h;98%
Stage #1: 1,1,1,3,3,3-hexamethyl-disilazane With C12H24KO6(1+)*Br3H(1-) In acetonitrile at 20℃; for 0.0166667h;
Stage #2: 4-fluorobenzylic alcohol In acetonitrile at 20℃; for 0.116667h;
97%
With 1,4-diazabicyclo[2.2.2]octane tribromide supported on magnetic Fe3O4 nanoparticles In neat (no solvent) at 20℃; for 0.666667h;97%
4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

4-fluorobenzyl iodide
3831-29-6

4-fluorobenzyl iodide

Conditions
ConditionsYield
With hydrogen iodide for 1h; Heating;98%
With chloro-trimethyl-silane; sodium iodide In acetonitrile 0 deg C, 10 min then up to r.t., 1 h;97%
With natural kaolinitic clay; sulfuric acid; potassium iodide In various solvent(s) for 0.0833333h; Irradiation; microwave;82%
With bis(1,5-cyclooctadiene)rhodium(I) trifluoromethanesulfonate; hydrogen; iodine; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In 1,2-dichloro-ethane at 20℃; under 22502.3 Torr; Autoclave; Schlenk technique;78%
With potassium fluoride; tetra-(n-butyl)ammonium iodide; N-ethyl-N,N-diisopropylamine; N,N`-sulfuryldiimidazole In N,N-dimethyl-formamide; trifluoroacetic acid at 20℃; for 0.2h;70%
4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

4-cyanophenol
767-00-0

4-cyanophenol

4-((4'-fluoro)benzyloxy)benzonitrile
56442-14-9

4-((4'-fluoro)benzyloxy)benzonitrile

Conditions
ConditionsYield
With F-DEAD-2; bis-phenyl-[4-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)phenyl]phosphine In tetrahydrofuran at 20℃; for 3h; Mitsunobu reaction;98%
With bis-(2-(1-adamantyl)ethyl) azodicarboxylate; triphenylphosphine Mitsunobu reaction;95%
With bis(3-(perfluoro-t-butyloxy)propyl)diazodicarboxylate; bis-phenyl-[4-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)phenyl]phosphine In tetrahydrofuran at 20℃; for 8h; Mitsunobu reaction; Inert atmosphere;90%
4-β-isocyanate-4'-tert-butyldimethylsilyloxy-4'-O-demethyl-4-desoxypodophyllotoxin
851166-94-4

4-β-isocyanate-4'-tert-butyldimethylsilyloxy-4'-O-demethyl-4-desoxypodophyllotoxin

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

4-β-(4-fluorobenzyloxycarbonyl)amino-4'-tert-butyldimethylsilyloxy-4'-O-demethyl-4-desoxypodophyllotoxin
851167-14-1

4-β-(4-fluorobenzyloxycarbonyl)amino-4'-tert-butyldimethylsilyloxy-4'-O-demethyl-4-desoxypodophyllotoxin

Conditions
ConditionsYield
In dichloromethane at 20℃;98%
4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

urea
57-13-6

urea

4-(4-fluorophenyl)-5-(methoxycarbonyl)-6-methyl-3,4-dihydropyrimidin-2(1H)-one
283593-12-4

4-(4-fluorophenyl)-5-(methoxycarbonyl)-6-methyl-3,4-dihydropyrimidin-2(1H)-one

Conditions
ConditionsYield
at 80℃; for 0.75h;98%
Stage #1: 4-fluorobenzylic alcohol With bismuth(III) nitrate In various solvent(s) at 50℃; for 0.0833333h;
Stage #2: acetoacetic acid methyl ester; urea In various solvent(s) at 90℃;
88%
4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

p-fluorobenzamide
824-75-9

p-fluorobenzamide

Conditions
ConditionsYield
With tert.-butylhydroperoxide; ammonia; oxygen In water; N,N-dimethyl-formamide at 80℃; under 1520.1 Torr; for 5h; Green chemistry;98%
With tert.-butylhydroperoxide; tetraethylammonium iodide; ammonium bicarbonate In 1,2-dichloro-ethane at 70℃; for 22h;77%
With tert.-butylhydroperoxide; ammonium hydroxide In water at 100℃; for 16h;72%
Multi-step reaction with 2 steps
1: cesium carbonate; styrene / iridium pentamethylcyclopentadienyl dichloride dimer / toluene / 24 h / 111 °C
2: 117 mg / hydroxylamine hydrochloride / iridium pentamethylcyclopentadienyl dichloride dimer / toluene / 16 h / 111 °C
View Scheme
With ammonium acetate; oxygen In tert-Amyl alcohol at 130℃; under 3800.26 Torr; for 18h; Reagent/catalyst; Autoclave;61 %Chromat.
4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

aniline
62-53-3

aniline

N-(p-fluorobenzyl)aniline
83444-25-1

N-(p-fluorobenzyl)aniline

Conditions
ConditionsYield
With 2,2,4,4,6,6-hexachloro-1,3,5-triaza-2,4,6-triphosphorine In 1,2,4-Trimethylbenzene at 160℃; for 15h; Inert atmosphere;98%
With C55H43ClN5P2Ru(1+)*Cl(1-); potassium hydroxide In toluene at 140℃; for 2h; Sealed tube;93%
With [(η5-pentamethylcyclopentadienyl)IrIIIbis-(κC-1,3-dimethylimidazol-2-ylidene)Cl]BF4; potassium tert-butylate In toluene at 80℃; for 12h;92%
4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

formic acid ethyl ester
109-94-4

formic acid ethyl ester

4-fluorobenzyl formate
1146963-53-2

4-fluorobenzyl formate

Conditions
ConditionsYield
With tribromomelamine In neat (no solvent) at 20℃; for 0.733333h; Green chemistry; chemoselective reaction;98%
With poly(4-vinylpyridinium tribromide) at 20℃; for 0.833333h; neat (no solvent);91%
Stage #1: formic acid ethyl ester With sulfuric acid; silica gel at 20℃;
Stage #2: 4-fluorobenzylic alcohol at 20℃; for 0.0833333h; chemoselective reaction;
piperidine
110-89-4

piperidine

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

4-fluorobenzylpiperidine
139592-92-0

4-fluorobenzylpiperidine

Conditions
ConditionsYield
With polystyrene supported triphenylphosphine ruthenium complex In toluene at 120℃; for 20h; Sealed tube; Flow reactor;98%
5-bromo-2-fluoropyridine
766-11-0

5-bromo-2-fluoropyridine

4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

5-bromo-2-((4-fluorobenzyl)oxy)pyridine
936343-08-7

5-bromo-2-((4-fluorobenzyl)oxy)pyridine

Conditions
ConditionsYield
Stage #1: 4-fluorobenzylic alcohol With sodium hydride In tetrahydrofuran at 0 - 20℃; for 1.5h; Reflux;
Stage #2: 5-bromo-2-fluoropyridine In tetrahydrofuran for 12h; Reflux;
98%
Stage #1: 4-fluorobenzylic alcohol With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 0.5h;
Stage #2: 5-bromo-2-fluoropyridine In tetrahydrofuran; mineral oil at 0 - 80℃; for 3h;
4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

acetic acid tert-butyl ester
540-88-5

acetic acid tert-butyl ester

tert-butyl 3-(4-fluorophenyl)propanoate
1049037-23-1

tert-butyl 3-(4-fluorophenyl)propanoate

Conditions
ConditionsYield
With tri-tert-butyl phosphine; potassium tert-butylate; nickel diacetate In 1,4-dioxane; toluene at 100℃; for 12h; Inert atmosphere; Glovebox; Schlenk technique;98%
With C22H34Cl2CoF3N5P2; potassium tert-butylate In toluene at 80℃; for 4h; Concentration; Inert atmosphere; Sealed tube; Glovebox;82%
With Ru(η(2)-2-(2'-pyridyl)phenyl)Cl(CO)(PPh3)2; potassium tert-butylate In toluene at 80℃; for 1.5h; Inert atmosphere; Schlenk technique; Green chemistry;82%
With C15H17ClIrNOP; potassium tert-butylate In toluene at 60℃; for 12h; Schlenk technique; Inert atmosphere; Glovebox;79%
4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

1,1,1-trifluoro-2-isocyanatoethane
371-92-6

1,1,1-trifluoro-2-isocyanatoethane

4-fluorobenzyl (2,2,2-trifluoroethyl)carbamate

4-fluorobenzyl (2,2,2-trifluoroethyl)carbamate

Conditions
ConditionsYield
at 20℃;98%
4-fluorobenzylic alcohol
459-56-3

4-fluorobenzylic alcohol

3,5-dinitrobenzoic acid
99-34-3

3,5-dinitrobenzoic acid

p-fluorobenzyl 3,5-dinitrobenzoate

p-fluorobenzyl 3,5-dinitrobenzoate

Conditions
ConditionsYield
With bis-(2-(1-adamantyl)ethyl) azodicarboxylate; triphenylphosphine In tetrahydrofuran at 20℃; Mitsunobu reaction;97%
With PhP(C6H4-p-(CH2)2C6F13)2; bis(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)diazo dicarboxylate In tetrahydrofuran

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