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Antimex Chemical Limied

Estriol 50-27-1 ;Estriol ;Estriol Description: White to practically white, odorless crystalline powder Specific Rotation: +54°~+62° Loss on drying: ≤0.5% Residue on Ignition: ≤0.1% Dilutions of Impurities 0,05mg/l: < 0,2

Estriol USP, EP5

Cas:50-27-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

Estriol

Cas:50-27-1

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Shaanxi New nine Material Technology Co., Ltd.

Our Advantage: 1. Rich experience We specialize in this filed for many years, our APIs exported to all over the world and and we established long friendly relations of cooperation with our clients. 2. Great quality,purity and favorable Good quali

Estriol

Cas:50-27-1

Min.Order:1 Kilogram

FOB Price: $10.0

Type:Trading Company

inquiry

Sinoway Industrial Co., Ltd.

Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c

99% up GMP DMF Estriol 50-27-1

Cas:50-27-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Dingyan Chem Co., Ltd

Item Spec. Result Appearance White or practically white crystalline powder Conforms Identification

High quality 50-27-1 Estriol

Cas:50-27-1

Min.Order:1 Kilogram

FOB Price: $1300.0 / 1600.0

Type:Trading Company

inquiry

Kono Chem Co.,Ltd

Specification for Top qualtiy Estriol CAS 50-27-1 with competitive price Appearance:powder Storage:store in cool and dry Package:according to customers' requirements Application:Pharmaceutical Transportation:

CAS:50-27-1 Estriol factory sales

Cas:50-27-1

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO

estriol manufacturer/supplier

Cas:50-27-1

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Wuhan Fortuna Chemical Co.,Ltd

1.High quality : the purity is 99% min . through multiple producing procedures. 2.Competitive price : low price because of our skilled production technolpgy ,save the production cost at most , and give big profit room to our customers

Estriol 50-27-1

Cas:50-27-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hebei yanxi chemical co.,LTD.

chengdu and import and export trade co., ltd., who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do res

Estriol

Cas:50-27-1

Min.Order:1 Kilogram

FOB Price: $1.0 / 3.0

Type:Manufacturers

inquiry

Hangzhou Think Chemical Co. Ltd

Estriol CAS No.:50-27-1 Name: Estriol Synonyms: 1,3,5(10)-Estratriene-3,16a,17b-triol; Estra-1,3,5(10)-triene-3,16alpha,17beta-triol Molecular Structure Molecular For

High purity Estriol CAS No.:50-27-1

Cas:50-27-1

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Other

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Estriol

Cas:50-27-1

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price API 99% Estriol 50-27-1 GMP Manufacturer

Cas:50-27-1

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Chengdu Lemeitian Pharmaceutical Technology Co,. Ltd

ADVANTAGE: 1. More than 3,000 Chinese medicine reference substances / standard products available from stock, issued on the same day, multiple cities can be delivered the next day 2. The products are provided with COA, HPLC, NMR, quality assurance,

Estriol

Cas:50-27-1

Min.Order:5 Milligram

Negotiable

Type:Manufacturers

inquiry

Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality Estriol

Cas:50-27-1

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

Estriol Manufacturer/High quality/Best price/In stock

Cas:50-27-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Estriol

Cas:50-27-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hubei DiBo chemical co., LTD

Name:Estriol CAS NO:50-27-1 Grade:Medical scientific research and export Molecular formula:C18H24O3 Molecular weight:288.3814 Product Quality 12 years of chemical raw materials Mature operation of the industry System stability Data storag

Estriol/ CAS:50-27-1/Estriol raw material/ high-quality

Cas:50-27-1

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

tianfu-chem_ Estriol 50-27-1

Cas:50-27-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

LIDE PHARMACEUTICALS LIMITED

LIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc. We are specialized in chemical synthesis, process development of pharmaceu

Estriol

Cas:50-27-1

Min.Order:1 Kilogram

FOB Price: $0.9 / 1.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufactu

CAS :50-27-1 Estriol

Cas:50-27-1

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 50-27-1 with best quality

Cas:50-27-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

hot sell Estriol

Cas:50-27-1

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:white crystalline powder Storage:Store in sealed containers

Hangzhou Sartort Biopharma Co., Ltd

Appearance:White or almost white crystalline powder Storage:Room temperature Package:1kg/drum, 25kg/drum Application:API Transportation:Express/Sea/Air Port:Any port in china

High Quality Estriol (USP, EP) Manufacturer Estriol Powder

Cas:50-27-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Estriol 50-27-1

Cas:50-27-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

HANWAYS CHEMPHARM CO.,LIMITED

Wuhan hanweishi Pharmchem Co., Ltd(Hanways chempharm) is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The leading products range are APIs, Hormones, Peptides

Estriol CAS 50-27-1

Cas:50-27-1

Min.Order:100 Kilogram

FOB Price: $1.0 / 5.0

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

roduct Name: Estriol Synonyms: TRIDESTRIN;(16-alpha,17-beta)-estra-1,3,5(10)-triene-3,16,17-triol;(16alpha,17beta)-Estra-1,3,5(10)-triene-3,16,17-triol;(16-alpha,17-beta)-oestra-1,3,5(10)-triene-3,16,17-triol;(16alpha,17beta)-Oestra-1,3,5(10)-trie

Estriol 50-27-1 USP38 top in the market

Cas:50-27-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

Estrogen drugs Estriol/CAS:50-27-1

Cas:50-27-1

Min.Order:1 Gram

FOB Price: $24.0 / 30.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates, steroids, pharmaceutical i

Estriol/Estriol quality supplier /50-27-1

Cas:50-27-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

2,4-dibromo-3,16α-dihydroxy-1,3,5(10)-estratrien-17-one
79258-14-3

2,4-dibromo-3,16α-dihydroxy-1,3,5(10)-estratrien-17-one

Estriol
50-27-1

Estriol

Conditions
ConditionsYield
With sodium tetrahydroborate; palladium dichloride In methanol at 0℃; for 2h;96%
With sodium borodeuteride; palladium dichloride In deuteromethanol at 0℃; for 1h;92%
Multi-step reaction with 4 steps
1: 85 percent / Ag2CO3 / benzene / 72 h / Ambient temperature
2: 95 percent / NaBH4, PdCl2 / methanol / 2 h / 0 °C
3: 65 percent / aq. 2M NaOH / methanol / Ambient temperature
4: 24 h / 38 °C / beef-liver β-glucuronidase, 0.1M acetate buffer (pH 4.6)
View Scheme
16α-hydroxyestrone
566-76-7

16α-hydroxyestrone

Estriol
50-27-1

Estriol

Conditions
ConditionsYield
With methanol; sodium tris(acetoxy)borohydride In 1,4-dioxane at 20 - 25℃;94%
estra-1,3,5(10)-triene-3,16α,17β-triol 3-methoxyethyl ether
123715-88-8

estra-1,3,5(10)-triene-3,16α,17β-triol 3-methoxyethyl ether

Estriol
50-27-1

Estriol

Conditions
ConditionsYield
With sec.-butyllithium In tetrahydrofuran; N,N-dimethyl-formamide at -78℃;90%
Estrone
53-16-7

Estrone

A

estradiol
50-28-2

estradiol

B

Estriol
50-27-1

Estriol

Conditions
ConditionsYield
Isolierung aus dem Harn von Maennern nach Injektion von (+)-O-Acetyl-oestron;
3-methoxy-estra-1,3,5(10)-triene-16α,17β-diol
1474-53-9

3-methoxy-estra-1,3,5(10)-triene-16α,17β-diol

Estriol
50-27-1

Estriol

Conditions
ConditionsYield
With hydrogen bromide; acetic acid
3,16α-diacetoxy-1,3,5(10)-estratrien-17-one
1247-71-8

3,16α-diacetoxy-1,3,5(10)-estratrien-17-one

Estriol
50-27-1

Estriol

Conditions
ConditionsYield
With lithium aluminium tetrahydride; diethyl ether; benzene
3,16α-diacetoxy-1,3,5(10)-estratrien-17-one
1247-71-8

3,16α-diacetoxy-1,3,5(10)-estratrien-17-one

A

Estriol
50-27-1

Estriol

Conditions
ConditionsYield
With lithium aluminium tetrahydride; diethyl ether
3,17β-diacetoxy-16α,17α-epoxy-estra-1,3,5(10)-triene
69744-63-4

3,17β-diacetoxy-16α,17α-epoxy-estra-1,3,5(10)-triene

Estriol
50-27-1

Estriol

Conditions
ConditionsYield
With lithium aluminium tetrahydride; diethyl ether; benzene
3-Hydroxyestra-1,3,5(10)-triene 16β,17β-Oxide
472-57-1

3-Hydroxyestra-1,3,5(10)-triene 16β,17β-Oxide

A

Estriol
50-27-1

Estriol

B

16,17-Epiestriol
793-89-5

16,17-Epiestriol

Conditions
ConditionsYield
With acetic acid Erwaermen des Reaktionsprodukts mit aethanol. KOH;
estradiol
50-28-2

estradiol

A

Estrone
53-16-7

Estrone

B

Estriol
50-27-1

Estriol

C

3,7α-dihydroxy-estra-1,3,5(10)-trien-17-one
2487-49-2

3,7α-dihydroxy-estra-1,3,5(10)-trien-17-one

D

6α-hydroxyestrone
1476-78-4

6α-hydroxyestrone

Conditions
ConditionsYield
With disodium hydrogenphosphate; potassium dihydrogenphosphate; D-glucose; oxygen; sodium chloride; calcium chloride; magnesium chloride at 37℃; for 0.166667h; Kinetics; Product distribution; Mechanism; <6,7-3H>-labeled, metabolism in uterine tissue from 6 months old prepubertal pigs;
Estrone
53-16-7

Estrone

A

estradiol
50-28-2

estradiol

B

Estriol
50-27-1

Estriol

C

3,7α-dihydroxy-estra-1,3,5(10)-trien-17-one
2487-49-2

3,7α-dihydroxy-estra-1,3,5(10)-trien-17-one

D

6α-hydroxyestrone
1476-78-4

6α-hydroxyestrone

Conditions
ConditionsYield
With disodium hydrogenphosphate; potassium dihydrogenphosphate; D-glucose; oxygen; sodium chloride; calcium chloride; magnesium chloride at 37℃; for 0.166667h; Kinetics; Product distribution; <6,7-3H>-labeled, metabolism in uterine tissue from 6 months old prepubertal pigs;
sodium 3,17β-dihydroxyestra-1,3,5(10)-trien-16α-yl-β-D-glucopyranosuronate
1852-44-4

sodium 3,17β-dihydroxyestra-1,3,5(10)-trien-16α-yl-β-D-glucopyranosuronate

Estriol
50-27-1

Estriol

Conditions
ConditionsYield
at 38℃; for 24h; beef-liver β-glucuronidase, 0.1M acetate buffer (pH 4.6);
16α,17β,19-trihydroxyandrost-4-en-3-one
99700-34-2

16α,17β,19-trihydroxyandrost-4-en-3-one

Estriol
50-27-1

Estriol

Conditions
ConditionsYield
for 1h; Mechanism; biosynthesis labelled with isotops;
16α,17β-dihydroxyandrost-4-ene-3,19-dione
99700-35-3

16α,17β-dihydroxyandrost-4-ene-3,19-dione

Estriol
50-27-1

Estriol

Conditions
ConditionsYield
for 0.5h; Mechanism; biosynthesis labelled with isotops;
Conditions
ConditionsYield
β-glucoronidase I In water at 37℃; for 0.166667h; Product distribution; substrate specifity of enzyme;
β-glucoronidase II In water at 37℃; for 0.166667h; Product distribution; substrate specifity of enzyme;
Conditions
ConditionsYield
β-glucoronidase II In water at 37℃; for 0.166667h; Product distribution; substrate specifity of enzyme;
2,4-dibromoestratriol
19590-54-6

2,4-dibromoestratriol

A

Estriol
50-27-1

Estriol

B

4-bromoestra-1,3,5(10)-triene-3,16α,17β-triol
99477-24-4

4-bromoestra-1,3,5(10)-triene-3,16α,17β-triol

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In ethanol Ambient temperature; Yield given;
estradiol
50-28-2

estradiol

A

4-Hydroxyestradiol
5976-61-4, 72704-99-5

4-Hydroxyestradiol

B

2-Hydroxyestradiol
362-05-0

2-Hydroxyestradiol

C

Estriol
50-27-1

Estriol

Conditions
ConditionsYield
With cytochrome P450 1A2; NADPH-generating system In phosphate buffer at 37℃; for 0.25h; pH=7.4; Enzyme kinetics; Further Variations:; Reagents; time; Oxidation;
diethyl ether
60-29-7

diethyl ether

3,17β-diacetoxy-16α,17α-epoxy-estra-1,3,5(10)-triene
69744-63-4

3,17β-diacetoxy-16α,17α-epoxy-estra-1,3,5(10)-triene

benzene
71-43-2

benzene

lithium alanate

lithium alanate

Estriol
50-27-1

Estriol

3,17β-dihydroxy-estratrien-(1,3,5(10))-one-(16)

3,17β-dihydroxy-estratrien-(1,3,5(10))-one-(16)

A

Estriol
50-27-1

Estriol

B

epiestriol
547-81-9

epiestriol

Conditions
ConditionsYield
With sodium amalgam; ethanol; acetic acid at 40℃;
ethanol
64-17-5

ethanol

16-oxoestradiol
6199-65-1, 566-75-6

16-oxoestradiol

acetic acid
64-19-7

acetic acid

sodium-amalgam

sodium-amalgam

A

Estriol
50-27-1

Estriol

B

epiestriol
547-81-9

epiestriol

Conditions
ConditionsYield
at 40℃;
Estrone
53-16-7

Estrone

Estriol
50-27-1

Estriol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: cupric bromide / methanol / 32 h / Heating
2: 90 percent / pyridine, sodium hydroxide / H2O / 3 h / Ambient temperature
3: 96 percent / NaBH4, PdCl2 / methanol / 2 h / 0 °C
View Scheme
Multi-step reaction with 6 steps
1: cupric bromide / methanol / 32 h / Heating
2: 90 percent / pyridine, sodium hydroxide / H2O / 3 h / Ambient temperature
3: 85 percent / Ag2CO3 / benzene / 72 h / Ambient temperature
4: 95 percent / NaBH4, PdCl2 / methanol / 2 h / 0 °C
5: 65 percent / aq. 2M NaOH / methanol / Ambient temperature
6: 24 h / 38 °C / beef-liver β-glucuronidase, 0.1M acetate buffer (pH 4.6)
View Scheme
Multi-step reaction with 3 steps
1: cupric bromide / methanol / 24 h / Heating
2: 90 percent / pyridine, sodium hydroxide / H2O / 3 h / Ambient temperature
3: 96 percent / NaBH4, PdCl2 / methanol / 2 h / 0 °C
View Scheme
methyl 3,17β-dihydroxyestra-1,3,5(10)-trien-16α-yl-2,3,4-tri-O-acetyl-β-D-glucopyranosuronate
18841-95-7

methyl 3,17β-dihydroxyestra-1,3,5(10)-trien-16α-yl-2,3,4-tri-O-acetyl-β-D-glucopyranosuronate

Estriol
50-27-1

Estriol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 65 percent / aq. 2M NaOH / methanol / Ambient temperature
2: 24 h / 38 °C / beef-liver β-glucuronidase, 0.1M acetate buffer (pH 4.6)
View Scheme
methyl 1-O-<2,4-dibromo-3-hydroxy-17-oxo-estra-1,3,5(10)-trien-16α-yl>-2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate
79258-13-2

methyl 1-O-<2,4-dibromo-3-hydroxy-17-oxo-estra-1,3,5(10)-trien-16α-yl>-2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate

Estriol
50-27-1

Estriol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 95 percent / NaBH4, PdCl2 / methanol / 2 h / 0 °C
2: 65 percent / aq. 2M NaOH / methanol / Ambient temperature
3: 24 h / 38 °C / beef-liver β-glucuronidase, 0.1M acetate buffer (pH 4.6)
View Scheme
2,4,16α-tribromo-3-hydroxy-1,3,5(10)-estratrien-17-one
79258-15-4

2,4,16α-tribromo-3-hydroxy-1,3,5(10)-estratrien-17-one

Estriol
50-27-1

Estriol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 90 percent / pyridine, sodium hydroxide / H2O / 3 h / Ambient temperature
2: 96 percent / NaBH4, PdCl2 / methanol / 2 h / 0 °C
View Scheme
Multi-step reaction with 5 steps
1: 90 percent / pyridine, sodium hydroxide / H2O / 3 h / Ambient temperature
2: 85 percent / Ag2CO3 / benzene / 72 h / Ambient temperature
3: 95 percent / NaBH4, PdCl2 / methanol / 2 h / 0 °C
4: 65 percent / aq. 2M NaOH / methanol / Ambient temperature
5: 24 h / 38 °C / beef-liver β-glucuronidase, 0.1M acetate buffer (pH 4.6)
View Scheme
estra-1,3,5(10),16-tetraene-3,17-diol diacetate
20592-42-1

estra-1,3,5(10),16-tetraene-3,17-diol diacetate

Estriol
50-27-1

Estriol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: bromine
2: lithium alanate; diethyl ether / Erwaermen des Reaktionsprodukts mit aethanol. Kalilauge
3: acetic acid / Erwaermen des Reaktionsprodukts mit aethanol. KOH
View Scheme
Multi-step reaction with 2 steps
1: peroxybenzoic acid; benzene
2: LiAlH4; diethyl ether; benzene
View Scheme
Multi-step reaction with 3 steps
1: 3-chloro-benzenecarboperoxoic acid / ethyl acetate / 7 - 20 °C
2: water; sulfuric acid / 1,4-dioxane / 10 - 20 °C
3: sodium tris(acetoxy)borohydride; methanol / 1,4-dioxane / 20 - 25 °C
View Scheme
16α-bromo-3-hydroxy-1,3,5(10)-estratrien-17-one 3-acetate
1239-35-6

16α-bromo-3-hydroxy-1,3,5(10)-estratrien-17-one 3-acetate

Estriol
50-27-1

Estriol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: lithium alanate; diethyl ether / Erwaermen des Reaktionsprodukts mit aethanol. Kalilauge
2: acetic acid / Erwaermen des Reaktionsprodukts mit aethanol. KOH
View Scheme
B-ipc-9-BBN

B-ipc-9-BBN

diethyl ether
60-29-7

diethyl ether

Estrone
53-16-7

Estrone

ethanolamine
141-43-5

ethanolamine

acetaldehyde
75-07-0

acetaldehyde

Estriol
50-27-1

Estriol

Estriol
50-27-1

Estriol

16-oxoestradiol
6199-65-1, 566-75-6

16-oxoestradiol

Conditions
ConditionsYield
With 4-methyl-morpholine; 6C6H15P*4CF3O3S(1-)*2Ru(2+); acetone at 65℃; for 5h; Inert atmosphere; Sealed tube;97%
Estriol
50-27-1

Estriol

2,4-dibromoestratriol
19590-54-6

2,4-dibromoestratriol

Conditions
ConditionsYield
With N-Bromosuccinimide In N,N-dimethyl-formamide for 24h; Ambient temperature;95%
Estriol
50-27-1

Estriol

acetic anhydride
108-24-7

acetic anhydride

3,16α,17β-Estratriol 16,17-diacetate
805-26-5

3,16α,17β-Estratriol 16,17-diacetate

Conditions
ConditionsYield
With boron trifluoride diethyl etherate In tetrahydrofuran at 0℃; for 4h; Schlenk technique;94%
With boron trifluoride diethyl etherate In tetrahydrofuran for 0.333333h; Ambient temperature; Yield given;
Estriol
50-27-1

Estriol

acetic anhydride
108-24-7

acetic anhydride

estriol triacetate
2284-32-4

estriol triacetate

Conditions
ConditionsYield
With pyridine for 24h; Ambient temperature;93.2%
at 100℃;
With pyridine at 95℃;
Cyclopentyl bromide
137-43-9

Cyclopentyl bromide

Estriol
50-27-1

Estriol

water
7732-18-5

water

quinestradol
1169-79-5

quinestradol

Conditions
ConditionsYield
With potassium hydroxide In ethanol90%
2,2,2-trichloroethoxysulfuryl 2-methyl-3-methylimidazolium triflate
1185733-70-3

2,2,2-trichloroethoxysulfuryl 2-methyl-3-methylimidazolium triflate

Estriol
50-27-1

Estriol

C20H25Cl3O6S
1313434-26-2

C20H25Cl3O6S

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane; N,N-dimethyl-formamide at 20℃; for 0.1h; chemoselective reaction;88%
Estriol
50-27-1

Estriol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

16α-(tert-butyldimethylsilyloxy)-1,3,5(10)-estratrien-3,17β-diol
104202-84-8

16α-(tert-butyldimethylsilyloxy)-1,3,5(10)-estratrien-3,17β-diol

Conditions
ConditionsYield
82%
tetrapropylammonium perruthennate
114615-82-6

tetrapropylammonium perruthennate

3,16α-Bis(dimethylthexylsilyl ether)

3,16α-Bis(dimethylthexylsilyl ether)

Estriol
50-27-1

Estriol

16α-hydroxyestrone
566-76-7

16α-hydroxyestrone

Conditions
ConditionsYield
In dichloromethane76%
2-chloroethyl methyl ether
627-42-9

2-chloroethyl methyl ether

Estriol
50-27-1

Estriol

estra-1,3,5(10)-triene-3,16α,17β-triol 3-methoxyethyl ether
123715-88-8

estra-1,3,5(10)-triene-3,16α,17β-triol 3-methoxyethyl ether

Conditions
ConditionsYield
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 90 - 95℃; for 15h;75%
Estriol
50-27-1

Estriol

NBD chloride
10199-89-0

NBD chloride

(8R,9S,13S,14S,16R,17R)-13-Methyl-3-(7-nitro-benzo[1,2,5]oxadiazol-4-yloxy)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-16,17-diol

(8R,9S,13S,14S,16R,17R)-13-Methyl-3-(7-nitro-benzo[1,2,5]oxadiazol-4-yloxy)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-16,17-diol

Conditions
ConditionsYield
With 18-crown-6 ether; potassium carbonate In acetonitrile at 80℃; for 0.5h;75%
Estriol
50-27-1

Estriol

10β-Fluoro-3-oxo-1,4-estradien-16α,17β-diol

10β-Fluoro-3-oxo-1,4-estradien-16α,17β-diol

Conditions
ConditionsYield
With Selectfluor In acetonitrile at 45℃; for 5h; Fluorination;73%
Estriol
50-27-1

Estriol

acetic acid
64-19-7

acetic acid

3,16α,17β-Estratriol 16,17-diacetate
805-26-5

3,16α,17β-Estratriol 16,17-diacetate

Conditions
ConditionsYield
With copper diacetate Heating;60%
Estriol
50-27-1

Estriol

2,4-diiodoestra-1,3,5(10)-triene-3,16α,17β-triol
65896-72-2

2,4-diiodoestra-1,3,5(10)-triene-3,16α,17β-triol

Conditions
ConditionsYield
With ammonium hydroxide; iodine In tetrahydrofuran; methanol for 0.5h;60%
Estriol
50-27-1

Estriol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

(13S,16R,17R)-3,17-bis(tert-butyldimethylsilyloxy)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-16-ol

(13S,16R,17R)-3,17-bis(tert-butyldimethylsilyloxy)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-16-ol

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide for 0.666667h;58%
Estriol
50-27-1

Estriol

acetic anhydride
108-24-7

acetic anhydride

(16α,17β)-16,17-dihydroxyestra-1(10),2,4-trien-3-yl acetate
17779-98-5

(16α,17β)-16,17-dihydroxyestra-1(10),2,4-trien-3-yl acetate

Conditions
ConditionsYield
Stage #1: Estriol With sodium hydroxide In propan-1-ol for 0.166667h;
Stage #2: acetic anhydride With potassium hydrogencarbonate In propan-1-ol
57%
Estriol
50-27-1

Estriol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

A

(13S,16R,17R)-3,16-bis(tert-butyldimethylsilyloxy)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-ol
134958-20-6

(13S,16R,17R)-3,16-bis(tert-butyldimethylsilyloxy)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-ol

B

(8R,9S,13S,14S,16R,17R)-3,16,17-Tris-(tert-butyl-dimethyl-silanyloxy)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene
185910-46-7

(8R,9S,13S,14S,16R,17R)-3,16,17-Tris-(tert-butyl-dimethyl-silanyloxy)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide for 0.666667h; Inert atmosphere; Sealed tube;A 49%
B 49%
Estriol
50-27-1

Estriol

A

4-bromoestra-1,3,5(10)-triene-3,16α,17β-triol
99477-24-4

4-bromoestra-1,3,5(10)-triene-3,16α,17β-triol

B

2-bromoestra-1,3,5(10)-triene-3,16α,17β-triol

2-bromoestra-1,3,5(10)-triene-3,16α,17β-triol

Conditions
ConditionsYield
With N-Bromosuccinimide In N,N-dimethyl-formamide for 24h; Ambient temperature;A 34%
B 37%
Estriol
50-27-1

Estriol

2-Iodoestriol

2-Iodoestriol

Conditions
ConditionsYield
With iodine; copper diacetate In acetic acid at 55℃; for 22h;35%
Estriol
50-27-1

Estriol

(8S,9S,13S,14S,16R,17R)-2,4,10-triazido-16,17-dihydroxy-13-methyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one

(8S,9S,13S,14S,16R,17R)-2,4,10-triazido-16,17-dihydroxy-13-methyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one

Conditions
ConditionsYield
With Amberlyst A26-resin bound iodine azide In acetonitrile at 20℃; for 3.5h; Catalytic behavior; Inert atmosphere;32%
2-(α-bromoacetyl)-phenoxathiin
6517-30-2

2-(α-bromoacetyl)-phenoxathiin

Estriol
50-27-1

Estriol

estriol 3-(2-α-acetylphenoxathiin) ether

estriol 3-(2-α-acetylphenoxathiin) ether

Conditions
ConditionsYield
With potassium hydroxide; 18-crown-6 ether In dichloromethane at 20℃;17%
Estriol
50-27-1

Estriol

3-methoxy-estra-1,3,5(10)-triene-16α,17β-diol
1474-53-9

3-methoxy-estra-1,3,5(10)-triene-16α,17β-diol

Conditions
ConditionsYield
With methanol
With methanol; diethyl ether; chloroform
Estriol
50-27-1

Estriol

Estrone
53-16-7

Estrone

Conditions
ConditionsYield
With potassium hydrogensulfate at 180 - 200℃; im Hochvakuum;
Estriol
50-27-1

Estriol

5ξ.10ξ-estranetriol-(3ξ.16α.17β)
76122-50-4, 91200-60-1, 91200-61-2

5ξ.10ξ-estranetriol-(3ξ.16α.17β)

Conditions
ConditionsYield
With hydrogenchloride; platinum Hydrogenation;
With ethanol; nickel at 175℃; under 110326 Torr; Hydrogenation;
Estriol
50-27-1

Estriol

2-methoxyestriol
1236-72-2

2-methoxyestriol

Estriol
50-27-1

Estriol

3-hydroxy-16,17-seco-estra-1,3,5(10)-triene-16,17-dioic acid
521-81-3

3-hydroxy-16,17-seco-estra-1,3,5(10)-triene-16,17-dioic acid

Conditions
ConditionsYield
With potassium hydroxide at 250 - 300℃;
With potassium hydroxide; water at 275℃;
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