Estriol 50-27-1 ;Estriol ;Estriol Description: White to practically white, odorless crystalline powder Specific Rotation: +54°~+62° Loss on drying: ≤0.5% Residue on Ignition: ≤0.1% Dilutions of Impurities 0,05mg/l: < 0,2
GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation
Our Advantage: 1. Rich experience We specialize in this filed for many years, our APIs exported to all over the world and and we established long friendly relations of cooperation with our clients. 2. Great quality,purity and favorable Good quali
Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c
Cas:50-27-1
Min.Order:1 Kilogram
Negotiable
Type:Trading Company
inquiryItem Spec. Result Appearance White or practically white crystalline powder Conforms Identification
Cas:50-27-1
Min.Order:1 Kilogram
FOB Price: $1300.0 / 1600.0
Type:Trading Company
inquirySpecification for Top qualtiy Estriol CAS 50-27-1 with competitive price Appearance:powder Storage:store in cool and dry Package:according to customers' requirements Application:Pharmaceutical Transportation:
We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO
1.High quality : the purity is 99% min . through multiple producing procedures. 2.Competitive price : low price because of our skilled production technolpgy ,save the production cost at most , and give big profit room to our customers
chengdu and import and export trade co., ltd., who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do res
Estriol CAS No.:50-27-1 Name: Estriol Synonyms: 1,3,5(10)-Estratriene-3,16a,17b-triol; Estra-1,3,5(10)-triene-3,16alpha,17beta-triol Molecular Structure Molecular For
Cas:50-27-1
Min.Order:1 Kilogram
FOB Price: $2.0
Type:Other
inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:50-27-1
Min.Order:1 Gram
FOB Price: $0.1
Type:Manufacturers
inquiryADVANTAGE: 1. More than 3,000 Chinese medicine reference substances / standard products available from stock, issued on the same day, multiple cities can be delivered the next day 2. The products are provided with COA, HPLC, NMR, quality assurance,
Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu
Cas:50-27-1
Min.Order:1 Kilogram
FOB Price: $1.0
Type:Manufacturers
inquiryDayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe
Cas:50-27-1
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Name:Estriol CAS NO:50-27-1 Grade:Medical scientific research and export Molecular formula:C18H24O3 Molecular weight:288.3814 Product Quality 12 years of chemical raw materials Mature operation of the industry System stability Data storag
Cas:50-27-1
Min.Order:25 Kilogram
FOB Price: $1.0 / 2.0
Type:Other
inquiryOur company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O
Cas:50-27-1
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryLIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc. We are specialized in chemical synthesis, process development of pharmaceu
With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufactu
Cas:50-27-1
Min.Order:1 Kilogram
FOB Price: $1.0 / 10.0
Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:50-27-1
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:white crystalline powder Storage:Store in sealed containers
Cas:50-27-1
Min.Order:100 Gram
Negotiable
Type:Other
inquiryAppearance:White or almost white crystalline powder Storage:Room temperature Package:1kg/drum, 25kg/drum Application:API Transportation:Express/Sea/Air Port:Any port in china
Cas:50-27-1
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery
Cas:50-27-1
Min.Order:10 Gram
FOB Price: $1.65
Type:Trading Company
inquiryWuhan hanweishi Pharmchem Co., Ltd(Hanways chempharm) is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The leading products range are APIs, Hormones, Peptides
Cas:50-27-1
Min.Order:100 Kilogram
FOB Price: $1.0 / 5.0
Type:Trading Company
inquiryroduct Name: Estriol Synonyms: TRIDESTRIN;(16-alpha,17-beta)-estra-1,3,5(10)-triene-3,16,17-triol;(16alpha,17beta)-Estra-1,3,5(10)-triene-3,16,17-triol;(16-alpha,17-beta)-oestra-1,3,5(10)-triene-3,16,17-triol;(16alpha,17beta)-Oestra-1,3,5(10)-trie
Cas:50-27-1
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryOur company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present
Cas:50-27-1
Min.Order:1 Gram
FOB Price: $24.0 / 30.0
Type:Trading Company
inquiryQingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates, steroids, pharmaceutical i
Cas:50-27-1
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiry2,4-dibromo-3,16α-dihydroxy-1,3,5(10)-estratrien-17-one
Estriol
Conditions | Yield |
---|---|
With sodium tetrahydroborate; palladium dichloride In methanol at 0℃; for 2h; | 96% |
With sodium borodeuteride; palladium dichloride In deuteromethanol at 0℃; for 1h; | 92% |
Multi-step reaction with 4 steps 1: 85 percent / Ag2CO3 / benzene / 72 h / Ambient temperature 2: 95 percent / NaBH4, PdCl2 / methanol / 2 h / 0 °C 3: 65 percent / aq. 2M NaOH / methanol / Ambient temperature 4: 24 h / 38 °C / beef-liver β-glucuronidase, 0.1M acetate buffer (pH 4.6) View Scheme |
Conditions | Yield |
---|---|
With methanol; sodium tris(acetoxy)borohydride In 1,4-dioxane at 20 - 25℃; | 94% |
estra-1,3,5(10)-triene-3,16α,17β-triol 3-methoxyethyl ether
Estriol
Conditions | Yield |
---|---|
With sec.-butyllithium In tetrahydrofuran; N,N-dimethyl-formamide at -78℃; | 90% |
Conditions | Yield |
---|---|
Isolierung aus dem Harn von Maennern nach Injektion von (+)-O-Acetyl-oestron; |
Conditions | Yield |
---|---|
With hydrogen bromide; acetic acid |
Conditions | Yield |
---|---|
With lithium aluminium tetrahydride; diethyl ether; benzene |
3,16α-diacetoxy-1,3,5(10)-estratrien-17-one
A
Estriol
B
17-epiestriol
Conditions | Yield |
---|---|
With lithium aluminium tetrahydride; diethyl ether |
3,17β-diacetoxy-16α,17α-epoxy-estra-1,3,5(10)-triene
Estriol
Conditions | Yield |
---|---|
With lithium aluminium tetrahydride; diethyl ether; benzene |
3-Hydroxyestra-1,3,5(10)-triene 16β,17β-Oxide
A
Estriol
B
16,17-Epiestriol
Conditions | Yield |
---|---|
With acetic acid Erwaermen des Reaktionsprodukts mit aethanol. KOH; |
estradiol
A
Estrone
B
Estriol
C
3,7α-dihydroxy-estra-1,3,5(10)-trien-17-one
D
6α-hydroxyestrone
Conditions | Yield |
---|---|
With disodium hydrogenphosphate; potassium dihydrogenphosphate; D-glucose; oxygen; sodium chloride; calcium chloride; magnesium chloride at 37℃; for 0.166667h; Kinetics; Product distribution; Mechanism; <6,7-3H>-labeled, metabolism in uterine tissue from 6 months old prepubertal pigs; |
Estrone
A
estradiol
B
Estriol
C
3,7α-dihydroxy-estra-1,3,5(10)-trien-17-one
D
6α-hydroxyestrone
Conditions | Yield |
---|---|
With disodium hydrogenphosphate; potassium dihydrogenphosphate; D-glucose; oxygen; sodium chloride; calcium chloride; magnesium chloride at 37℃; for 0.166667h; Kinetics; Product distribution; <6,7-3H>-labeled, metabolism in uterine tissue from 6 months old prepubertal pigs; |
sodium 3,17β-dihydroxyestra-1,3,5(10)-trien-16α-yl-β-D-glucopyranosuronate
Estriol
Conditions | Yield |
---|---|
at 38℃; for 24h; beef-liver β-glucuronidase, 0.1M acetate buffer (pH 4.6); |
16α,17β,19-trihydroxyandrost-4-en-3-one
Estriol
Conditions | Yield |
---|---|
for 1h; Mechanism; biosynthesis labelled with isotops; |
16α,17β-dihydroxyandrost-4-ene-3,19-dione
Estriol
Conditions | Yield |
---|---|
for 0.5h; Mechanism; biosynthesis labelled with isotops; |
Conditions | Yield |
---|---|
β-glucoronidase I In water at 37℃; for 0.166667h; Product distribution; substrate specifity of enzyme; | |
β-glucoronidase II In water at 37℃; for 0.166667h; Product distribution; substrate specifity of enzyme; |
3,16α-dihydroxy-1,3,5(10)-estratrien-17β-yl-β-D-glucopyranosiduronic acid
B
Estriol
Conditions | Yield |
---|---|
β-glucoronidase II In water at 37℃; for 0.166667h; Product distribution; substrate specifity of enzyme; |
Conditions | Yield |
---|---|
β-glucoronidase II In water at 37℃; for 0.166667h; Product distribution; substrate specifity of enzyme; |
2,4-dibromoestratriol
A
Estriol
B
4-bromoestra-1,3,5(10)-triene-3,16α,17β-triol
Conditions | Yield |
---|---|
With hydrogen; palladium on activated charcoal In ethanol Ambient temperature; Yield given; |
estradiol
A
4-Hydroxyestradiol
B
2-Hydroxyestradiol
C
Estriol
Conditions | Yield |
---|---|
With cytochrome P450 1A2; NADPH-generating system In phosphate buffer at 37℃; for 0.25h; pH=7.4; Enzyme kinetics; Further Variations:; Reagents; time; Oxidation; |
diethyl ether
3,17β-diacetoxy-16α,17α-epoxy-estra-1,3,5(10)-triene
benzene
Estriol
Conditions | Yield |
---|---|
With sodium amalgam; ethanol; acetic acid at 40℃; |
ethanol
16-oxoestradiol
acetic acid
A
Estriol
B
epiestriol
Conditions | Yield |
---|---|
at 40℃; |
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: cupric bromide / methanol / 32 h / Heating 2: 90 percent / pyridine, sodium hydroxide / H2O / 3 h / Ambient temperature 3: 96 percent / NaBH4, PdCl2 / methanol / 2 h / 0 °C View Scheme | |
Multi-step reaction with 6 steps 1: cupric bromide / methanol / 32 h / Heating 2: 90 percent / pyridine, sodium hydroxide / H2O / 3 h / Ambient temperature 3: 85 percent / Ag2CO3 / benzene / 72 h / Ambient temperature 4: 95 percent / NaBH4, PdCl2 / methanol / 2 h / 0 °C 5: 65 percent / aq. 2M NaOH / methanol / Ambient temperature 6: 24 h / 38 °C / beef-liver β-glucuronidase, 0.1M acetate buffer (pH 4.6) View Scheme | |
Multi-step reaction with 3 steps 1: cupric bromide / methanol / 24 h / Heating 2: 90 percent / pyridine, sodium hydroxide / H2O / 3 h / Ambient temperature 3: 96 percent / NaBH4, PdCl2 / methanol / 2 h / 0 °C View Scheme |
methyl 3,17β-dihydroxyestra-1,3,5(10)-trien-16α-yl-2,3,4-tri-O-acetyl-β-D-glucopyranosuronate
Estriol
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 65 percent / aq. 2M NaOH / methanol / Ambient temperature 2: 24 h / 38 °C / beef-liver β-glucuronidase, 0.1M acetate buffer (pH 4.6) View Scheme |
methyl 1-O-<2,4-dibromo-3-hydroxy-17-oxo-estra-1,3,5(10)-trien-16α-yl>-2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate
Estriol
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 95 percent / NaBH4, PdCl2 / methanol / 2 h / 0 °C 2: 65 percent / aq. 2M NaOH / methanol / Ambient temperature 3: 24 h / 38 °C / beef-liver β-glucuronidase, 0.1M acetate buffer (pH 4.6) View Scheme |
2,4,16α-tribromo-3-hydroxy-1,3,5(10)-estratrien-17-one
Estriol
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 90 percent / pyridine, sodium hydroxide / H2O / 3 h / Ambient temperature 2: 96 percent / NaBH4, PdCl2 / methanol / 2 h / 0 °C View Scheme | |
Multi-step reaction with 5 steps 1: 90 percent / pyridine, sodium hydroxide / H2O / 3 h / Ambient temperature 2: 85 percent / Ag2CO3 / benzene / 72 h / Ambient temperature 3: 95 percent / NaBH4, PdCl2 / methanol / 2 h / 0 °C 4: 65 percent / aq. 2M NaOH / methanol / Ambient temperature 5: 24 h / 38 °C / beef-liver β-glucuronidase, 0.1M acetate buffer (pH 4.6) View Scheme |
estra-1,3,5(10),16-tetraene-3,17-diol diacetate
Estriol
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: bromine 2: lithium alanate; diethyl ether / Erwaermen des Reaktionsprodukts mit aethanol. Kalilauge 3: acetic acid / Erwaermen des Reaktionsprodukts mit aethanol. KOH View Scheme | |
Multi-step reaction with 2 steps 1: peroxybenzoic acid; benzene 2: LiAlH4; diethyl ether; benzene View Scheme | |
Multi-step reaction with 3 steps 1: 3-chloro-benzenecarboperoxoic acid / ethyl acetate / 7 - 20 °C 2: water; sulfuric acid / 1,4-dioxane / 10 - 20 °C 3: sodium tris(acetoxy)borohydride; methanol / 1,4-dioxane / 20 - 25 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: lithium alanate; diethyl ether / Erwaermen des Reaktionsprodukts mit aethanol. Kalilauge 2: acetic acid / Erwaermen des Reaktionsprodukts mit aethanol. KOH View Scheme |
Estriol
16-oxoestradiol
Conditions | Yield |
---|---|
With 4-methyl-morpholine; 6C6H15P*4CF3O3S(1-)*2Ru(2+); acetone at 65℃; for 5h; Inert atmosphere; Sealed tube; | 97% |
Estriol
2,4-dibromoestratriol
Conditions | Yield |
---|---|
With N-Bromosuccinimide In N,N-dimethyl-formamide for 24h; Ambient temperature; | 95% |
Conditions | Yield |
---|---|
With boron trifluoride diethyl etherate In tetrahydrofuran at 0℃; for 4h; Schlenk technique; | 94% |
With boron trifluoride diethyl etherate In tetrahydrofuran for 0.333333h; Ambient temperature; Yield given; |
Conditions | Yield |
---|---|
With pyridine for 24h; Ambient temperature; | 93.2% |
at 100℃; | |
With pyridine at 95℃; |
Conditions | Yield |
---|---|
With potassium hydroxide In ethanol | 90% |
2,2,2-trichloroethoxysulfuryl 2-methyl-3-methylimidazolium triflate
Estriol
C20H25Cl3O6S
Conditions | Yield |
---|---|
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane; N,N-dimethyl-formamide at 20℃; for 0.1h; chemoselective reaction; | 88% |
Estriol
tert-butyldimethylsilyl chloride
16α-(tert-butyldimethylsilyloxy)-1,3,5(10)-estratrien-3,17β-diol
Conditions | Yield |
---|---|
82% |
Conditions | Yield |
---|---|
In dichloromethane | 76% |
2-chloroethyl methyl ether
Estriol
estra-1,3,5(10)-triene-3,16α,17β-triol 3-methoxyethyl ether
Conditions | Yield |
---|---|
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 90 - 95℃; for 15h; | 75% |
Estriol
NBD chloride
Conditions | Yield |
---|---|
With 18-crown-6 ether; potassium carbonate In acetonitrile at 80℃; for 0.5h; | 75% |
Estriol
Conditions | Yield |
---|---|
With Selectfluor In acetonitrile at 45℃; for 5h; Fluorination; | 73% |
Conditions | Yield |
---|---|
With copper diacetate Heating; | 60% |
Estriol
2,4-diiodoestra-1,3,5(10)-triene-3,16α,17β-triol
Conditions | Yield |
---|---|
With ammonium hydroxide; iodine In tetrahydrofuran; methanol for 0.5h; | 60% |
Estriol
tert-butyldimethylsilyl chloride
Conditions | Yield |
---|---|
With 1H-imidazole In N,N-dimethyl-formamide for 0.666667h; | 58% |
Estriol
acetic anhydride
(16α,17β)-16,17-dihydroxyestra-1(10),2,4-trien-3-yl acetate
Conditions | Yield |
---|---|
Stage #1: Estriol With sodium hydroxide In propan-1-ol for 0.166667h; Stage #2: acetic anhydride With potassium hydrogencarbonate In propan-1-ol | 57% |
Estriol
tert-butyldimethylsilyl chloride
A
(13S,16R,17R)-3,16-bis(tert-butyldimethylsilyloxy)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-ol
B
(8R,9S,13S,14S,16R,17R)-3,16,17-Tris-(tert-butyl-dimethyl-silanyloxy)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene
Conditions | Yield |
---|---|
With 1H-imidazole In N,N-dimethyl-formamide for 0.666667h; Inert atmosphere; Sealed tube; | A 49% B 49% |
Estriol
A
4-bromoestra-1,3,5(10)-triene-3,16α,17β-triol
Conditions | Yield |
---|---|
With N-Bromosuccinimide In N,N-dimethyl-formamide for 24h; Ambient temperature; | A 34% B 37% |
Estriol
Conditions | Yield |
---|---|
With iodine; copper diacetate In acetic acid at 55℃; for 22h; | 35% |
Estriol
Conditions | Yield |
---|---|
With Amberlyst A26-resin bound iodine azide In acetonitrile at 20℃; for 3.5h; Catalytic behavior; Inert atmosphere; | 32% |
Conditions | Yield |
---|---|
With potassium hydroxide; 18-crown-6 ether In dichloromethane at 20℃; | 17% |
diazomethane
Estriol
3-methoxy-estra-1,3,5(10)-triene-16α,17β-diol
Conditions | Yield |
---|---|
With methanol | |
With methanol; diethyl ether; chloroform |
Conditions | Yield |
---|---|
With potassium hydrogensulfate at 180 - 200℃; im Hochvakuum; |
Estriol
5ξ.10ξ-estranetriol-(3ξ.16α.17β)
Conditions | Yield |
---|---|
With hydrogenchloride; platinum Hydrogenation; | |
With ethanol; nickel at 175℃; under 110326 Torr; Hydrogenation; |
Conditions | Yield |
---|---|
With potassium hydroxide at 250 - 300℃; | |
With potassium hydroxide; water at 275℃; |
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