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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

Phenylpropiolic acid

Cas:637-44-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Phenyl Propiolic Acid supplier in China

Cas:637-44-5

Min.Order:1 Metric Ton

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Type:Manufacturers

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Large Stock 99.0% Phenylpropiolic acid 637-44-5 Producer

Cas:637-44-5

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

3-Phenyl-2-propynoic acid

Cas:637-44-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer supply CAS 637-44-5 with best quality

Cas:637-44-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2-Propynoic acid,3-phenyl- 637-44-5

Cas:637-44-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

Phenylpropiolic acid CAS:637-44-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic interm

Phenylpropiolic acid CAS:637-44-5

Cas:637-44-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2-Propynoic acid,3-phenyl-

Cas:637-44-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:637-44-5

Cas:637-44-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

Phenyl Propiolic Acid

Cas:637-44-5

Min.Order:0

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Phenylpropiolic acid

Cas:637-44-5

Min.Order:0 Metric Ton

Negotiable

Type:Other

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2-Propynoic acid,3-phenyl-

Cas:637-44-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

Phenyl propiolic acid/High quality/Best price

Cas:637-44-5

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Phenyl Propiolic Acid

Cas:637-44-5

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Shanghai Minstar Chemical Co., Ltd

Phenylpropiolic acid Chemical Properties Melting point 135-137 °C (lit.) Boiling point 225.74°C (rough estimate) density 1.1674 (rough estimate) refractive index 1.5550 (estimate) storage temp. 0-6°C pka pK1:2.269 (

Phenylpropiolic acid

Cas:637-44-5

Min.Order:1 Gram

FOB Price: $66.0

Type:Lab/Research institutions

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

Phenyl propiolic acid/High quality/Best price

Cas:637-44-5

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

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Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

Phenyl propiolic acid/High quality/Best price

Cas:637-44-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

Phenyl propiolic acid/High quality/Best price

Cas:637-44-5

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

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Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

Phenyl propiolic acid/High quality/Best price

Cas:637-44-5

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

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Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

Phenylpropiolic acid cas no. 637-44-5 98%

Cas:637-44-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Greenutra Resource Inc

Phenylpropiolic acidAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air

Phenylpropiolic acid

Cas:637-44-5

Min.Order:0

Negotiable

Type:Trading Company

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GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

Phenylpropiolic Acid

Cas:637-44-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

Phenylpropiolic acid

Cas:637-44-5

Min.Order:0

Negotiable

Type:Other

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Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

3-Phenylpropiolic acid

Cas:637-44-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Lonwin Chemical Group Limited

Shanghai Lonwin Chemical company is a subsidiary of Lonwin Industry Group Limited, was established in 2011 and is headquartered in Shanghai, adjacent to China National Convention and Exhibition Center and Hongqiao transportation hub.Lonwinchem is

Best price Phenyl Propiolic Acid 637-44-5

Cas:637-44-5

Min.Order:100 Kilogram

FOB Price: $100.0 / 150.0

Type:Other

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Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

Phenylpropiolic Acid

Cas:637-44-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

Phenyl Propiolic Acid

Cas:637-44-5

Min.Order:0

Negotiable

Type:Manufacturers

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Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

Phenylpropiolic acid

Cas:637-44-5

Min.Order:0

Negotiable

Type:Manufacturers

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Hunan chemfish Pharmaceutical co.,Ltd

Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as

Phenylpropiolic acid

Cas:637-44-5

Min.Order:0

Negotiable

Type:Manufacturers

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Wuxi TAA Chemical Industry Co.,LTD.

1.A strong technical force and advanced processing equipments. The quality of the products has been strictly inspected and all kinds of index have reached or exceeded domestic and international standards.2. Now we have established long-term stable re

High quality Phenylpropiolic acid cas NO.: 637-44-5

Cas:637-44-5

Min.Order:0

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Type:Other

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Synthetic route

carbon dioxide
124-38-9

carbon dioxide

phenylacetylene
536-74-3

phenylacetylene

phenylpropyolic acid
637-44-5

phenylpropyolic acid

Conditions
ConditionsYield
With potassium carbonate In dimethyl sulfoxide at 50℃; under 760.051 Torr; for 24h; Catalytic behavior; Reagent/catalyst; Temperature;100%
With caesium carbonate In dimethyl sulfoxide at 50℃; under 760.051 Torr; for 16h; Catalytic behavior; Reagent/catalyst; Solvent; Temperature; Sealed tube;99%
With caesium carbonate In dimethyl sulfoxide at 50℃; under 750.075 Torr; for 12h; Reagent/catalyst; Time; Schlenk technique;99.1%
carbon dioxide
1111-72-4

carbon dioxide

phenylacetylene
536-74-3

phenylacetylene

phenylpropyolic acid
637-44-5

phenylpropyolic acid

Conditions
ConditionsYield
Stage #1: carbon dioxide; phenylacetylene With diethoxymethylane; potassium tert-butylate at 40℃; for 2h; Schlenk technique;
Stage #2: With hydrogenchloride In water Reagent/catalyst; Schlenk technique;
98%
carbon dioxide
124-38-9

carbon dioxide

diethoxy(methyl)(phenylethynyl)silane

diethoxy(methyl)(phenylethynyl)silane

phenylpropyolic acid
637-44-5

phenylpropyolic acid

Conditions
ConditionsYield
Stage #1: carbon dioxide; diethoxy(methyl)(phenylethynyl)silane With potassium tert-butylate at 40℃; for 2h; Schlenk technique;
Stage #2: With hydrogenchloride In water Reagent/catalyst; Schlenk technique;
98%
4-((tert-butyldimethylsilyl)oxy)benzyl 3-phenylpropiolate

4-((tert-butyldimethylsilyl)oxy)benzyl 3-phenylpropiolate

phenylpropyolic acid
637-44-5

phenylpropyolic acid

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran at 20℃; for 0.5h;97%
iodobenzene
591-50-4

iodobenzene

Propiolic acid
471-25-0

Propiolic acid

phenylpropyolic acid
637-44-5

phenylpropyolic acid

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; 1,4-di(diphenylphosphino)-butane In dimethyl sulfoxide at 50℃; for 5h; Sonogashira coupling; Sealed flask;96%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diisopropylamine In N,N-dimethyl-formamide for 5h; Sonogashira Cross-Coupling; Inert atmosphere;65%
With cesium hydroxide In water at 60℃; for 12h; Sonogashira coupling; Inert atmosphere;58%
carbon dioxide
124-38-9

carbon dioxide

1-Phenyl-2-(trimethylsilyl)acetylene
2170-06-1

1-Phenyl-2-(trimethylsilyl)acetylene

phenylpropyolic acid
637-44-5

phenylpropyolic acid

Conditions
ConditionsYield
Stage #1: carbon dioxide; 1-Phenyl-2-(trimethylsilyl)acetylene With cesium fluoride In dimethyl sulfoxide at 20℃; for 3h; Schlenk technique;
Stage #2: With hydrogenchloride In water at 0℃; pH=> 1; Reagent/catalyst; Solvent;
96%
With 18-crown-6 ether; cesium fluoride In dimethyl sulfoxide at 30℃; under 760.051 Torr; for 20h; Schlenk technique;94%
Yb(2+)*2C6H5C2CO2(1-) = (C6H5C2CO2)2Yb

Yb(2+)*2C6H5C2CO2(1-) = (C6H5C2CO2)2Yb

A

ytterbium hydroxide

ytterbium hydroxide

B

phenylpropyolic acid
637-44-5

phenylpropyolic acid

Conditions
ConditionsYield
With water In pentane addn. of a mixture (1:3) of water and pentane under Ar at room temperature; removing solvent and volatile compound (PhCCCO2H) by vac. condensation;;A 94.3%
B 89.6%
bromobenzene
108-86-1

bromobenzene

Propiolic acid
471-25-0

Propiolic acid

phenylpropyolic acid
637-44-5

phenylpropyolic acid

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); 1,8-diazabicyclo[5.4.0]undec-7-ene In dimethyl sulfoxide at 35℃; for 24h; Sonogashira Cross-Coupling;93%
With 2-dicyclohexylphosphino-2′,6′-dimethoxybiphenyl; tris-(dibenzylideneacetone)dipalladium(0); tetra-n-butylammoniumfluoride trihydrate In 1-methyl-pyrrolidin-2-one; water at 50℃; for 4h;42%
With 2-dicyclohexylphosphino-2′,6′-dimethoxybiphenyl; bis(η3-allyl-μ-chloropalladium(II)); tetra-n-butylammoniumfluoride trihydrate In 1-methyl-pyrrolidin-2-one; water at 50℃; for 16h; Inert atmosphere;
With tetrakis(triphenylphosphine) palladium(0); 1,8-diazabicyclo[5.4.0]undec-7-ene In dimethyl sulfoxide for 24h;
tert-butyldimethylsilyl 3-phenylpropiolate

tert-butyldimethylsilyl 3-phenylpropiolate

phenylpropyolic acid
637-44-5

phenylpropyolic acid

Conditions
ConditionsYield
Stage #1: C15H20O2Si; carbon tetrabromide In methanol at 20℃; for 0.5h; Irradiation;
Stage #2: In methanol at 20℃; for 5h;
92%
(2-methoxyethoxy)methyl 3-phenylpropiolate

(2-methoxyethoxy)methyl 3-phenylpropiolate

phenylpropyolic acid
637-44-5

phenylpropyolic acid

Conditions
ConditionsYield
With carbon tetrabromide In isopropyl alcohol for 1.5h; Heating;91%
3-Phenyl-2-propyn-1-ol
1504-58-1

3-Phenyl-2-propyn-1-ol

phenylpropyolic acid
637-44-5

phenylpropyolic acid

Conditions
ConditionsYield
With 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hypochlorite; sodium chlorite In acetonitrile at 35℃; pH 6.7;90%
With sodium hypochlorite; sodium chlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical In aq. phosphate buffer; water; acetonitrile at 35℃; pH=6.7; Green chemistry;90%
Multi-step reaction with 2 steps
1: TEMPO; poly[4-(diacetoxyiodo)styrene] / acetone / 4 h / 20 °C
2: aq. TEMPO; poly[4-(diacetoxyiodo)styrene] / acetone / 24 h / 20 °C
View Scheme
With sodium chlorite; Me-AZADO+Cl- In acetonitrile at 25℃; for 0.5h; pH=6.8; aq. phosphate buffer;
tert-butyldiphenylsilyl 3-phenylpropiolate

tert-butyldiphenylsilyl 3-phenylpropiolate

phenylpropyolic acid
637-44-5

phenylpropyolic acid

Conditions
ConditionsYield
With water; N,N-dimethyl-formamide at 70℃; for 0.5h; Green chemistry; chemoselective reaction;90%
Stage #1: C25H24O2Si; carbon tetrabromide In methanol at 20℃; for 0.5h; Irradiation;
Stage #2: In methanol at 20℃; for 48h;
61%
phenylpropynoic acid ethyl ester
2216-94-6

phenylpropynoic acid ethyl ester

phenylpropyolic acid
637-44-5

phenylpropyolic acid

Conditions
ConditionsYield
With sodium hydroxide In ethanol for 1.5h;84%
With aluminium(III) iodide In acetonitrile for 0.5h; Heating;80%
With water; sodium hydroxide In ethanol at 50℃; for 1.5h;56%
Phenyl triflate
17763-67-6

Phenyl triflate

Propiolic acid
471-25-0

Propiolic acid

phenylpropyolic acid
637-44-5

phenylpropyolic acid

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); 1,8-diazabicyclo[5.4.0]undec-7-ene In dimethyl sulfoxide at 35℃; for 24h; Sonogashira Cross-Coupling;84%
phenylpropyolic acid
637-44-5

phenylpropyolic acid

Conditions
ConditionsYield
With potassium hydroxide In ethanol for 6h; Reflux;75.9%
With potassium hydroxide In ethanol at 85℃; for 36h;73%
phenylethynylmagnesium bromide
6738-06-3

phenylethynylmagnesium bromide

carbon dioxide
124-38-9

carbon dioxide

phenylpropyolic acid
637-44-5

phenylpropyolic acid

Conditions
ConditionsYield
Stage #1: phenylethynylmagnesium bromide; carbon dioxide In tetrahydrofuran at 20℃; under 3000.3 Torr; gas-liquid flow reactor assembly;
Stage #2: With polymer-supported sulfonic acid In tetrahydrofuran
75%
Phenylpropargyl aldehyde
2579-22-8

Phenylpropargyl aldehyde

A

benzoic acid
65-85-0

benzoic acid

B

phenylpropyolic acid
637-44-5

phenylpropyolic acid

Conditions
ConditionsYield
With hydrogenchloride; sodium chlorite; sodium dihydrogenphosphate; dihydrogen peroxide In water; acetonitrile at 10℃; for 1h;A 6%
B 74%
Phenylpropargyl aldehyde
2579-22-8

Phenylpropargyl aldehyde

phenylpropyolic acid
637-44-5

phenylpropyolic acid

Conditions
ConditionsYield
With Oxone; ethylenediaminetetraacetic acid; sodium hydrogencarbonate In acetone; acetonitrile at 0 - 2℃; for 3.5h; Oxidation;73%
With poly[4-(diacetoxyiodo)styrene]; 2,2,6,6-tetramethyl-piperidine-N-oxyl In acetone at 20℃; for 24h;
Multi-step reaction with 2 steps
1: 70 percent / acetic acid; diethyl ether / 1 h / -10 °C
2: 27.4 percent / KOH, MnO2 / benzene / 3 h / Ambient temperature; other solvent, without MnO2
View Scheme
With potassium permanganate In water; acetonitrile
carbon dioxide
124-38-9

carbon dioxide

phenylacetylene
536-74-3

phenylacetylene

A

1,4-diphenyl-1,3-butadiyne
886-66-8

1,4-diphenyl-1,3-butadiyne

B

phenylpropyolic acid
637-44-5

phenylpropyolic acid

Conditions
ConditionsYield
With [tris(3,5-bis(trifluoromethyl)pyrazolate)tricopper(I)] In N,N-dimethyl-formamide at 20℃; under 760.051 Torr; for 12h;A 10%
B 72%
Stage #1: carbon dioxide; phenylacetylene With sodium carbonate; N,N,N,N,-tetramethylethylenediamine; copper(l) chloride In acetonitrile at 20℃; for 24h;
Stage #2: With hydrogenchloride In dichloromethane; water pH=1;
A 10%
B 60%
N-methoxy-3-phenylpropiolamide

N-methoxy-3-phenylpropiolamide

phenylpropyolic acid
637-44-5

phenylpropyolic acid

Conditions
ConditionsYield
With tert.-butylnitrite; water at 29℃; for 0.583333h;72%
2-(3-phenyl-1-trifluoromethanesulfonyloxy-prop-2-ynylidene)-malonic acid

2-(3-phenyl-1-trifluoromethanesulfonyloxy-prop-2-ynylidene)-malonic acid

phenylpropyolic acid
637-44-5

phenylpropyolic acid

Conditions
ConditionsYield
With water; sodium hydrogencarbonate at 20℃; for 12h; Elimination;71%
phenylpropynoic acid methyl ester
4891-38-7

phenylpropynoic acid methyl ester

phenylpropyolic acid
637-44-5

phenylpropyolic acid

Conditions
ConditionsYield
With pyrographite; sodium hydroxide In water at 20℃; for 24h;71%
With water; sodium hydroxide In ethanol Inert atmosphere;
With sodium hydroxide In methanol; water at 20℃; for 3h;
2-hydroxy-4-phenyl-3-butynenitrile
84452-21-1

2-hydroxy-4-phenyl-3-butynenitrile

phenylpropyolic acid
637-44-5

phenylpropyolic acid

Conditions
ConditionsYield
With manganese(IV) oxide In diethyl ether at 20 - 25℃; for 19h;66.6%
carbon dioxide
124-38-9

carbon dioxide

4,4,5,5-tetramethyl-2-phenylethynyl-[1,3,2]dioxaborolane
159087-45-3

4,4,5,5-tetramethyl-2-phenylethynyl-[1,3,2]dioxaborolane

phenylpropyolic acid
637-44-5

phenylpropyolic acid

Conditions
ConditionsYield
With copper(l) iodide; cesium fluoride; sodium t-butanolate; 1,3-bis[2,6-diisopropylphenyl]imidazolium chloride In 2-methyltetrahydrofuran at 120℃; for 24h; Solvent; Sealed tube;63%
chloroform
67-66-3

chloroform

phenyl(phenylethynyl)iodonium tosylate
79069-32-2

phenyl(phenylethynyl)iodonium tosylate

A

iodobenzene
591-50-4

iodobenzene

B

phenylpropyolic acid
637-44-5

phenylpropyolic acid

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; potassium hydroxide at 50℃; for 1h; Carbonylation;A n/a
B 61%
2,3-dibromo-3-phenylpropanoic acid
6286-30-2

2,3-dibromo-3-phenylpropanoic acid

phenylpropyolic acid
637-44-5

phenylpropyolic acid

Conditions
ConditionsYield
With potassium hydroxide In methanol Heating;58.7%
Reaktion ueber mehrere Stufen;
Multi-step reaction with 2 steps
1: 56 percent / KOH / methanol / Heating
2: 57.5 percent / KOH / methanol / Heating
View Scheme
Multi-step reaction with 2 steps
1: water
2: diethyl ether; sodium
View Scheme
With potassium hydroxide for 2h; Reflux; Inert atmosphere; Schlenk technique;5.7 g
(E)-2-Bromo-3-phenyl-acrylic acid
15894-30-1

(E)-2-Bromo-3-phenyl-acrylic acid

phenylpropyolic acid
637-44-5

phenylpropyolic acid

Conditions
ConditionsYield
With potassium hydroxide In methanol Heating;57.5%
phenylpropyolic acid
637-44-5

phenylpropyolic acid

phenylpropiolyl chloride
7299-58-3

phenylpropiolyl chloride

Conditions
ConditionsYield
With thionyl chloride In dichloromethane for 12h; Inert atmosphere; Reflux;100%
With thionyl chloride In dichloromethane at 40℃; for 16h;80%
With thionyl chloride In tetrachloromethane at 30 - 40℃; for 2h;73%
phenylpropyolic acid
637-44-5

phenylpropyolic acid

4-phenylnaphtho[2,3-c]furan-1,3-dione
1985-37-1

4-phenylnaphtho[2,3-c]furan-1,3-dione

Conditions
ConditionsYield
Stage #1: phenylpropyolic acid With triethylamine In dichloromethane at 20℃; for 1.5h; Schlenk technique; Inert atmosphere;
Stage #2: With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide In dichloromethane; 1,2-dichloro-ethane at 0 - 20℃; Temperature; Time; Reagent/catalyst; Schlenk technique; Inert atmosphere;
100%
With 1-ethyl-piperidine; N,N-bis[2-oxo-3-oxazolidinyl]phosphorodiamidic chloride In dichloromethane at 20℃; for 0.75h;97%
With palladium diacetate; caesium carbonate; triphenylphosphine In acetonitrile at 20℃; for 0.05h; Reagent/catalyst;96%
phenylpropyolic acid
637-44-5

phenylpropyolic acid

phenylacetylene
536-74-3

phenylacetylene

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0)100%
With [Au(DPB)SbF6]2(cod) In 1,2-dichloro-ethane at 20℃; for 24h; Inert atmosphere;24%
With water at 120℃; im geschlossenen Rohr;
phenylpropyolic acid
637-44-5

phenylpropyolic acid

phenylpropynoic acid methyl ester
4891-38-7

phenylpropynoic acid methyl ester

Conditions
ConditionsYield
In diethyl ether100%
In diethyl ether70%
S,S-dimethyl dithiocarbonate
868-84-8

S,S-dimethyl dithiocarbonate

phenylpropyolic acid
637-44-5

phenylpropyolic acid

(E)-3-Methylsulfanyl-3-phenyl-acrylic acid
109480-88-8

(E)-3-Methylsulfanyl-3-phenyl-acrylic acid

Conditions
ConditionsYield
With potassium hydroxide at 25 - 60℃; for 0.166667h;100%
S,S-diethyl dithiocarbonate
623-80-3

S,S-diethyl dithiocarbonate

phenylpropyolic acid
637-44-5

phenylpropyolic acid

(E)-3-Ethylsulfanyl-3-phenyl-acrylic acid
109480-89-9

(E)-3-Ethylsulfanyl-3-phenyl-acrylic acid

Conditions
ConditionsYield
With potassium hydroxide at 25 - 60℃; for 0.166667h;100%
S,S'-di-n-butyl dithiocarbonate
55716-09-1

S,S'-di-n-butyl dithiocarbonate

phenylpropyolic acid
637-44-5

phenylpropyolic acid

(E)-3-Butylsulfanyl-3-phenyl-acrylic acid
109480-90-2

(E)-3-Butylsulfanyl-3-phenyl-acrylic acid

Conditions
ConditionsYield
With potassium hydroxide at 90℃; for 0.5h;100%
ethyl iodide
75-03-6

ethyl iodide

phenylpropyolic acid
637-44-5

phenylpropyolic acid

phenylpropynoic acid ethyl ester
2216-94-6

phenylpropynoic acid ethyl ester

Conditions
ConditionsYield
With caesium carbonate In acetonitrile for 1.5h; Heating;100%
With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 2h; Reagent/catalyst; Solvent; Inert atmosphere;68%
morpholine
110-91-8

morpholine

phenylpropyolic acid
637-44-5

phenylpropyolic acid

1-(morpholin-4-yl)-3-phenylprop-2-yn-1-one
95969-89-4

1-(morpholin-4-yl)-3-phenylprop-2-yn-1-one

Conditions
ConditionsYield
Stage #1: phenylpropyolic acid With (chloro-phenylthio-methylene)dimethylammonium chloride In dichloromethane at 0℃; for 0.5h;
Stage #2: morpholine In dichloromethane at 20℃; for 12h;
100%
With oxalyl dichloride; triethylamine In dichloromethane at 0 - 20℃; for 5h; Schlenk technique; Inert atmosphere;84%
Stage #1: phenylpropyolic acid With thionyl chloride In dichloromethane at 40℃; for 2h;
Stage #2: morpholine In benzene at 10℃; for 1h;
4-bromo-3,5-dimethylphenol
7463-51-6

4-bromo-3,5-dimethylphenol

phenylpropyolic acid
637-44-5

phenylpropyolic acid

4-bromo-3,-5-dimethyl-phenyl 3-phenylpropiolate
267901-42-8

4-bromo-3,-5-dimethyl-phenyl 3-phenylpropiolate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 9h; Cooling with ice;100%
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 9h; Cooling with ice;100%
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 9h; Cooling with ice;100%
With dmap; dicyclohexyl-carbodiimide at 20℃; Esterification;80%
phenylacetic acid
103-82-2

phenylacetic acid

3-dimethylamino-1-(4-methylphenyl)propanamine
917351-49-6

3-dimethylamino-1-(4-methylphenyl)propanamine

4-Methoxyphenylacetic acid
104-01-8

4-Methoxyphenylacetic acid

(E)-3-phenylacrylic acid
140-10-3

(E)-3-phenylacrylic acid

3-(4-methoxyphenyl)propanoic acid
1929-29-9

3-(4-methoxyphenyl)propanoic acid

(E)-3-(4-methoxyphenyl)acrylic acid
943-89-5

(E)-3-(4-methoxyphenyl)acrylic acid

4-Trifluoromethylphenylacetic acid
32857-62-8

4-Trifluoromethylphenylacetic acid

3-<4'-(trifluoromethyl)phenyl>-2-propenoic acid
2062-26-2, 87212-84-8, 16642-92-5

3-<4'-(trifluoromethyl)phenyl>-2-propenoic acid

3-(4-trifluoromethylphenyl)propionic acid
53473-36-2

3-(4-trifluoromethylphenyl)propionic acid

phenylpropyolic acid
637-44-5

phenylpropyolic acid

3-Phenylpropionic acid
501-52-0

3-Phenylpropionic acid

A

N-[3-dimethylamino-1-(4-methylphenyl)propyl]cinnamic amide

N-[3-dimethylamino-1-(4-methylphenyl)propyl]cinnamic amide

B

N-[3-dimethylamino-1-(4-methylphenyl)propyl]-3-phenylpropiolic amide

N-[3-dimethylamino-1-(4-methylphenyl)propyl]-3-phenylpropiolic amide

C

N-[3-dimethylamino-1-(4-methylphenyl)propyl]-2-phenylacetamide

N-[3-dimethylamino-1-(4-methylphenyl)propyl]-2-phenylacetamide

D

N-[3-dimethylamino-1-(4-methylphenyl)propyl]-2-(4-trifluoromethylphenyl)acetamide

N-[3-dimethylamino-1-(4-methylphenyl)propyl]-2-(4-trifluoromethylphenyl)acetamide

E

N-[3-dimethylamino-1-(4-methylphenyl)propyl]-2-(4-methoxyphenyl)acetamide

N-[3-dimethylamino-1-(4-methylphenyl)propyl]-2-(4-methoxyphenyl)acetamide

F

N-[3-dimethylamino-1-(4-methylphenyl)propyl]-3-phenylpropionamide

N-[3-dimethylamino-1-(4-methylphenyl)propyl]-3-phenylpropionamide

G

N-[3-dimethylamino-1-(4-methylphenyl)propyl]-3-(4-trifluoromethylphenyl)propionamide

N-[3-dimethylamino-1-(4-methylphenyl)propyl]-3-(4-trifluoromethylphenyl)propionamide

H

N-[3-dimethylamino-1-(4-methylphenyl)propyl]-3-(4-methoxyphenyl)propionamide

N-[3-dimethylamino-1-(4-methylphenyl)propyl]-3-(4-methoxyphenyl)propionamide

I

N-[3-dimethylamino-1-(4-methylphenyl)propyl]-4-(trifluoromethyl)cinnamamide

N-[3-dimethylamino-1-(4-methylphenyl)propyl]-4-(trifluoromethyl)cinnamamide

J

N-[3-dimethylamino-1-(4-methylphenyl)propyl]-4-methoxycinnamamide

N-[3-dimethylamino-1-(4-methylphenyl)propyl]-4-methoxycinnamamide

Conditions
ConditionsYield
With polyvinylpyridine polymer-supported dimethylaminopyridine; PS-carbodiimide In dichloromethane at 20℃; for 96h; Polystyrene;A 100%
B 100%
C 93%
D 98%
E 93%
F 96%
G 78%
H 98%
I 56%
J 87%
phenylacetic acid
103-82-2

phenylacetic acid

3-dimethylamino-1-(2-naphthyl)propanamine
917351-50-9

3-dimethylamino-1-(2-naphthyl)propanamine

4-Methoxyphenylacetic acid
104-01-8

4-Methoxyphenylacetic acid

(E)-3-phenylacrylic acid
140-10-3

(E)-3-phenylacrylic acid

3-(4-methoxyphenyl)propanoic acid
1929-29-9

3-(4-methoxyphenyl)propanoic acid

(E)-3-(4-methoxyphenyl)acrylic acid
943-89-5

(E)-3-(4-methoxyphenyl)acrylic acid

4-Trifluoromethylphenylacetic acid
32857-62-8

4-Trifluoromethylphenylacetic acid

3-<4'-(trifluoromethyl)phenyl>-2-propenoic acid
2062-26-2, 87212-84-8, 16642-92-5

3-<4'-(trifluoromethyl)phenyl>-2-propenoic acid

3-(4-trifluoromethylphenyl)propionic acid
53473-36-2

3-(4-trifluoromethylphenyl)propionic acid

phenylpropyolic acid
637-44-5

phenylpropyolic acid

3-Phenylpropionic acid
501-52-0

3-Phenylpropionic acid

A

N-[3-dimethylamino-1-(2-naphthyl)propyl]-2-(4-trifluoromethylphenyl)acetamide

N-[3-dimethylamino-1-(2-naphthyl)propyl]-2-(4-trifluoromethylphenyl)acetamide

B

N-[3-dimethylamino-1-(2-naphthyl)propyl]-2-(4-methoxyphenyl)acetamide

N-[3-dimethylamino-1-(2-naphthyl)propyl]-2-(4-methoxyphenyl)acetamide

C

N-[3-dimethylamino-1-(2-naphthyl)propyl]-2-phenylacetamide

N-[3-dimethylamino-1-(2-naphthyl)propyl]-2-phenylacetamide

D

N-[3-dimethylamino-1-(2-naphthyl)propyl]-3-phenylpropionamide

N-[3-dimethylamino-1-(2-naphthyl)propyl]-3-phenylpropionamide

E

N-[3-dimethylamino-1-(2-naphthyl)propyl]-3-(4-trifluoromethylphenyl)propionamide

N-[3-dimethylamino-1-(2-naphthyl)propyl]-3-(4-trifluoromethylphenyl)propionamide

F

N-[3-dimethylamino-1-(2-naphthyl)propyl]-3-(4-methoxyphenyl)propionamide

N-[3-dimethylamino-1-(2-naphthyl)propyl]-3-(4-methoxyphenyl)propionamide

G

N-[3-dimethylamino-1-(2-naphthyl)propyl]cinnamamide

N-[3-dimethylamino-1-(2-naphthyl)propyl]cinnamamide

H

N-[3-dimethylamino-1-(2-naphthyl)propyl]-4-(trifluoromethyl)cinnamamide

N-[3-dimethylamino-1-(2-naphthyl)propyl]-4-(trifluoromethyl)cinnamamide

I

N-[3-dimethylamino-1-(2-naphthyl)propyl]-4-methoxycinnamamide

N-[3-dimethylamino-1-(2-naphthyl)propyl]-4-methoxycinnamamide

J

N-[3-dimethylamino-1-(2-naphthyl)propyl]-3-phenylpropiolamide

N-[3-dimethylamino-1-(2-naphthyl)propyl]-3-phenylpropiolamide

Conditions
ConditionsYield
With polyvinylpyridine polymer-supported dimethylaminopyridine; PS-carbodiimide In dichloromethane at 20℃; for 96h; Polystyrene;A 88%
B 79%
C 67%
D 66%
E 84%
F 94%
G 76%
H 100%
I 100%
J 100%
1-(4-chlorophenyl)-N3,N3-dimethylpropane-1,3-diamine
885672-69-5

1-(4-chlorophenyl)-N3,N3-dimethylpropane-1,3-diamine

phenylacetic acid
103-82-2

phenylacetic acid

4-Methoxyphenylacetic acid
104-01-8

4-Methoxyphenylacetic acid

(E)-3-phenylacrylic acid
140-10-3

(E)-3-phenylacrylic acid

3-(4-methoxyphenyl)propanoic acid
1929-29-9

3-(4-methoxyphenyl)propanoic acid

(E)-3-(4-methoxyphenyl)acrylic acid
943-89-5

(E)-3-(4-methoxyphenyl)acrylic acid

4-Trifluoromethylphenylacetic acid
32857-62-8

4-Trifluoromethylphenylacetic acid

3-<4'-(trifluoromethyl)phenyl>-2-propenoic acid
2062-26-2, 87212-84-8, 16642-92-5

3-<4'-(trifluoromethyl)phenyl>-2-propenoic acid

3-(4-trifluoromethylphenyl)propionic acid
53473-36-2

3-(4-trifluoromethylphenyl)propionic acid

phenylpropyolic acid
637-44-5

phenylpropyolic acid

3-Phenylpropionic acid
501-52-0

3-Phenylpropionic acid

A

N-[1-(4-chlorophenyl)-3-dimethylaminopropyl]-2-phenylacetamide
885673-16-5

N-[1-(4-chlorophenyl)-3-dimethylaminopropyl]-2-phenylacetamide

B

N-[1-(4-chlorophenyl)-3-dimethylaminopropyl]-2-(4-trifluoromethylphenyl)acetamide

N-[1-(4-chlorophenyl)-3-dimethylaminopropyl]-2-(4-trifluoromethylphenyl)acetamide

C

N-[1-(4-chlorophenyl)-3-dimethylaminopropyl]-2-(4-methoxyphenyl)acetamide

N-[1-(4-chlorophenyl)-3-dimethylaminopropyl]-2-(4-methoxyphenyl)acetamide

D

N-[1-(4-chlorophenyl)-3-dimethylaminopropyl]-3-phenylpropionamide

N-[1-(4-chlorophenyl)-3-dimethylaminopropyl]-3-phenylpropionamide

E

N-[1-(4-chlorophenyl)-3-dimethylaminopropyl]-3-(4-trifluoromethylphenyl)propionamide

N-[1-(4-chlorophenyl)-3-dimethylaminopropyl]-3-(4-trifluoromethylphenyl)propionamide

F

N-[1-(4-chlorophenyl)-3-dimethylaminopropyl]-3-(4-methoxyphenyl)propionamide

N-[1-(4-chlorophenyl)-3-dimethylaminopropyl]-3-(4-methoxyphenyl)propionamide

G

N-[1-(4-chlorophenyl)-3-dimethylaminopropyl]cinnamamide

N-[1-(4-chlorophenyl)-3-dimethylaminopropyl]cinnamamide

H

N-[1-(4-chlorophenyl)-3-dimethylaminopropyl]-4-(trifluoromethyl)cinnamamide

N-[1-(4-chlorophenyl)-3-dimethylaminopropyl]-4-(trifluoromethyl)cinnamamide

I

N-[1-(4-chlorophenyl)-3-dimethylaminopropyl]-4-methoxycinnamamide

N-[1-(4-chlorophenyl)-3-dimethylaminopropyl]-4-methoxycinnamamide

J

N-[1-(4-chlorophenyl)-3-dimethylaminopropyl]-3-phenylpropiolamide

N-[1-(4-chlorophenyl)-3-dimethylaminopropyl]-3-phenylpropiolamide

Conditions
ConditionsYield
With polyvinylpyridine polymer-supported dimethylaminopyridine; PS-carbodiimide In dichloromethane at 20℃; for 96h; Polystyrene;A 92%
B 96%
C 96%
D 92%
E 83%
F 81%
G 83%
H 97%
I 83%
J 100%
phenylpropyolic acid
637-44-5

phenylpropyolic acid

d-3-phenylpropiolic acid
1033320-59-0

d-3-phenylpropiolic acid

Conditions
ConditionsYield
With water-d2 at 20℃; for 0.5h;100%
With d(4)-methanol at 20℃; for 0.5h; Inert atmosphere; Schlenk technique;
phenylpropyolic acid
637-44-5

phenylpropyolic acid

1,4-diphenyl-1,3-butadiyne
886-66-8

1,4-diphenyl-1,3-butadiyne

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide at 130℃; for 48h;100%
With copper(l) iodide; 1,10-Phenanthroline; potassium carbonate In dimethyl sulfoxide at 100℃; for 12h; Reagent/catalyst;97%
With tetrakis(triphenylphosphine) palladium(0); silver carbonate In N,N-dimethyl-formamide at 130℃; for 20h; Inert atmosphere; Sealed tube;96%
4'-methyl-biphenyl-4-ol
26191-64-0

4'-methyl-biphenyl-4-ol

phenylpropyolic acid
637-44-5

phenylpropyolic acid

4-(4-methylphenyl)phenyl 3-phenyl-propiolate

4-(4-methylphenyl)phenyl 3-phenyl-propiolate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 11h; Cooling with ice;100%
ethanol
64-17-5

ethanol

phenylpropyolic acid
637-44-5

phenylpropyolic acid

phenylpropynoic acid ethyl ester
2216-94-6

phenylpropynoic acid ethyl ester

Conditions
ConditionsYield
Stage #1: phenylpropyolic acid With N-(methyl)-N-(p-toluenesulfonyl)ethynylamine In dichloromethane at 20℃;
Stage #2: ethanol With N,N,N'N'-tetramethyl-1,3-propanediamine In acetonitrile at 20℃; for 24h;
99%
With fluorosulfonyl fluoride; N-ethyl-N,N-diisopropylamine In 1,2-dichloro-ethane at 20℃; for 5h;99%
With graphene oxide at 100℃; for 24h; Catalytic behavior; Reagent/catalyst; Temperature;98%
phenylpropyolic acid
637-44-5

phenylpropyolic acid

3-Phenylpropionic acid
501-52-0

3-Phenylpropionic acid

Conditions
ConditionsYield
With LaNi5 hydride In tetrahydrofuran; methanol 1) 0 deg C, 2 h, 2) r.t., 15 h;99%
With ferrous ammonium sulphate hexahydrate; isopropyl β-D-thiogalactopyranoside In aq. phosphate buffer at 37℃; for 48h;92%
With water; palladium diacetate; 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane In dichloromethane at 25℃; for 12h; Schlenk technique; Inert atmosphere;71%
phenylpropyolic acid
637-44-5

phenylpropyolic acid

1-iodo-2-phenylethyne
932-88-7

1-iodo-2-phenylethyne

Conditions
ConditionsYield
With N-iodo-succinimide; tetrabutylammonium trifluoroacetate In 1,2-dichloro-ethane at 20℃; for 0.25h; iododecarboxylation;99%
With N-iodo-succinimide; triethylamine In dichloromethane at 20℃; for 0.0833333h; Hunsdiecker reaction;97%
With 1-iodo-3,5,5-trimethylhydantoin; triethylamine In dichloromethane at 20℃; for 0.0833333h; Concentration; Reagent/catalyst;97%
benzyl bromide
100-39-0

benzyl bromide

phenylpropyolic acid
637-44-5

phenylpropyolic acid

benzyl 3-phenyl-2-propynoate
63888-21-1

benzyl 3-phenyl-2-propynoate

Conditions
ConditionsYield
With potassium fluoride; tetra(n-butyl)ammonium hydrogensulfate In tetrahydrofuran at 20℃; for 3h;99%
With copper(l) iodide; caesium carbonate; acetonitrile at 60℃; for 24h;99%
Stage #1: phenylpropyolic acid With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.166667h;
Stage #2: benzyl bromide In N,N-dimethyl-formamide for 66h;
93%
phenylpropyolic acid
637-44-5

phenylpropyolic acid

benzene
71-43-2

benzene

3,3-diphenyl-indan-1-one
55010-17-8

3,3-diphenyl-indan-1-one

Conditions
ConditionsYield
trifluorormethanesulfonic acid99%
With aluminum tri-bromide at 60℃; for 1h;30%
Triethyl orthoacetate
78-39-7

Triethyl orthoacetate

phenylpropyolic acid
637-44-5

phenylpropyolic acid

phenylpropynoic acid ethyl ester
2216-94-6

phenylpropynoic acid ethyl ester

Conditions
ConditionsYield
In various solvent(s) at 80℃; for 0.5h;99%
C20H16O2

C20H16O2

phenylpropyolic acid
637-44-5

phenylpropyolic acid

C29H20O3

C29H20O3

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide at 0℃;99%
C20H16O2

C20H16O2

phenylpropyolic acid
637-44-5

phenylpropyolic acid

C29H20O3

C29H20O3

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide at 0℃;99%
C21H15F3O2

C21H15F3O2

phenylpropyolic acid
637-44-5

phenylpropyolic acid

C30H19F3O3

C30H19F3O3

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide at 0℃;99%
C23H22O2

C23H22O2

phenylpropyolic acid
637-44-5

phenylpropyolic acid

C32H26O3

C32H26O3

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide at 0℃;99%
3-(1-naphthyl)-1-phenylprop-2-yn-1-ol

3-(1-naphthyl)-1-phenylprop-2-yn-1-ol

phenylpropyolic acid
637-44-5

phenylpropyolic acid

C28H18O2

C28H18O2

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide at 0℃;99%
2-Methylene-1-butanol
4435-54-5

2-Methylene-1-butanol

phenylpropyolic acid
637-44-5

phenylpropyolic acid

2-ethylallyl 3-phenylpropiolate
1130965-04-6

2-ethylallyl 3-phenylpropiolate

Conditions
ConditionsYield
With dmap; diisopropyl-carbodiimide In dichloromethane at 25℃; for 4h; Inert atmosphere;99%
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 25℃; for 10h;
3-methoxy-1-iodobenzene
766-85-8

3-methoxy-1-iodobenzene

phenylpropyolic acid
637-44-5

phenylpropyolic acid

1-methoxy-3-(phenylethynyl)benzene
37696-01-8

1-methoxy-3-(phenylethynyl)benzene

Conditions
ConditionsYield
With copper(l) iodide; potassium carbonate; triphenylphosphine In dimethyl sulfoxide at 90℃; for 24h; Inert atmosphere;99%
With copper(l) iodide; potassium carbonate; triphenylphosphine In dimethyl sulfoxide at 100℃; for 24h; Inert atmosphere;99%
Stage #1: phenylpropyolic acid With silver(l) oxide In N,N-dimethyl-formamide at 20℃; for 0.0833333h; Inert atmosphere;
Stage #2: 3-methoxy-1-iodobenzene With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; triphenylphosphine; lithium iodide In N,N-dimethyl-formamide at 70℃; for 2h; Sonogashira coupling; Inert atmosphere;
86%

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