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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Methyl L-phenylalaninate hydrochloride

Cas:7524-50-7

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality L-Phenylalanine Methyl Ester Hydrochloride supplier in China

Cas:7524-50-7

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Wuhan Fortuna Chemical Co.,Ltd

Unique advantages Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White to off-white powder Storage:cool dry place Package:25kg/drum Application:biochemical Transportation:by cour

Manufacturer high quality Methyl L-phenylalaninate hydrochloride Cas 7524-50-7 with good price

Cas:7524-50-7

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

The company has a professional R & D team, mature technology, very competitive prices and stable high quality products for customers to order high quality and low price product efforts! Appearance:White or off-white Solid Storage:Sealed, dry, m

L-Phenylalanine Methyl Ester Hydrochloride

Cas:7524-50-7

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply L-Phenylalanine Methyl Ester Hydrochloride

Cas:7524-50-7

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% 7524-50-7 H-Phe-OMe·HCl Manufacturer

Cas:7524-50-7

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

ANQING CHICO PHARMACEUTICAL CO.,LTD.

High quality. Factory supply. In stock. Best price.1.Quick response within 24 hours;2.Best quality in your requirement;?3.We pay more attention on delivery time, and usually ship on time;4.Under the premise of safety and effectiveness, we can produce

Methyl L-phenylalaninate hydrochloride

Cas:7524-50-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

L-Phenylalanine methyl ester hydrochloride

Cas:7524-50-7

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer supply CAS 7524-50-7 with best quality

Cas:7524-50-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product name L-Phenylalanine methyl ester hydrochloride Alias methyl L-phenylalaninate hydrochloride; H-Phe-OMe.HCl; H-Phe-OMe*HCl; (2S)-1-methoxy-1-oxo-3-phenylpropan-2-aminium; H-Phe-OMe·HC

L-Phenylalanine methyl ester hydrochloride CAS:7524-50-7

Cas:7524-50-7

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

Jinlan Pharm-Drugs Technology Co.,Limited (with its export company Hangzhou Royall Import & Export Co.,Ltd.)is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int’l Airport and Shangha

High purity L-Phenylalanine methyl ester HCL 7524-50-7

Cas:7524-50-7

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White Crystalline Powder Storage:Store in sealed conta

7524-50-7 Methyl L-phenylalaninate hydrochloride

Cas:7524-50-7

Min.Order:10 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Methyl L-phenylalaninate hydrochloride 7524-50-7

Cas:7524-50-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Methyl L-phenylalaninate hydrochloride

Cas:7524-50-7

Min.Order:1 Kilogram

FOB Price: $68.0 / 75.0

Type:Trading Company

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:7524-50-7

Cas:7524-50-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

H-Phe-OMe.Cl

Cas:7524-50-7

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

H-Phe-OMe.Cl

Cas:7524-50-7

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

METHYL L-PHENYLALANINATE HYDROCHLORIDE

Cas:7524-50-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Methyl L-phenylalaninate hydrochloride

Cas:7524-50-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Competitive Price High Quality Fast Delivery custom-made Welcome to Henan Tianfu Chemical Co., Ltd. website. Our company engages in Sodium Tripolyphosphate (STPP) and Sodium Hexametabphosphate (SHMP) production; development of noble me

7524-50-7,Methyl L-phenylalaninate hydrochloride

Cas:7524-50-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

H-Phe-OMe.HCl

Cas:7524-50-7

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

Methyl L-phenylalaninate hydrochloride Basic information Product Name: Methyl L-phenylalaninate hydrochloride Synonyms: L-Phenylalanine methyl ester hydrochloride,98%;H-Phe-OMe·HCl Methyl L-phenylalaninate;L-Phe-OMe.HCL;Methyl L-phenyla

Methyl L-phenylalaninate hydrochloride

Cas:7524-50-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

H-Phe-OMe.Cl

Cas:7524-50-7

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Siwei Development Group Ltd.

Product name: L-Phenylalanine Methyl Ester HCL CAS No,: 7524-50-7 Molecule Formula:C10H14NO2 Molecule Weight:180.22 Purity: 99.0% Package: 25kg/drum Description:White crystalline powder Manufacture Standards:Enterprise Standard

Best Quality L-Phenylalanine Methyl Ester HCL

Cas:7524-50-7

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

H-Phe-OMe.Cl

Cas:7524-50-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

H-Phe-OMe.Cl

Cas:7524-50-7

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service and h

Methyl L-phenylalaninate hydrochloride

Cas:7524-50-7

Min.Order:0

Negotiable

Type:Other

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

L-Phenylalanine methyl ester hydrochloride

Cas:7524-50-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

Methyl L-phenylalaninate hydrochloride

Cas:7524-50-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe

Methyl L-phenylalaninate hydrochloride

Cas:7524-50-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

methanol
67-56-1

methanol

L-phenylalanine
63-91-2

L-phenylalanine

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

Conditions
ConditionsYield
With thionyl chloride 1.) from 0 deg C to RT, 100 min, 2.) reflux, 2 h;100%
With thionyl chloride for 2h; Heating;100%
With thionyl chloride at 20℃;100%
L-phenylalanine
63-91-2

L-phenylalanine

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

Conditions
ConditionsYield
With thionyl chloride In methanol100%
With thionyl chloride In methanol at 0 - 20℃;100%
With thionyl chloride In methanol98%
(S)-2-tert-butoxycarbonylamino-3-phenyl-propionic acid methyl ester
51987-73-6

(S)-2-tert-butoxycarbonylamino-3-phenyl-propionic acid methyl ester

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In ethyl acetate at 0℃; for 2h;100%
With hydrogenchloride In 1,4-dioxane for 2h;
With hydrogenchloride In 1,4-dioxane at 21 - 23℃; for 1h;
With hydrogenchloride In 1,4-dioxane at 21 - 23℃; for 1h;
L-phenylalanine
63-91-2

L-phenylalanine

2,2-dimethoxy-propane
77-76-9

2,2-dimethoxy-propane

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

Conditions
ConditionsYield
With hydrogenchloride at 20℃; for 18h;99%
With hydrogenchloride Ambient temperature;
With hydrogenchloride at 20℃;
N-formyl-L-phenylalanine-methylester
2311-21-9

N-formyl-L-phenylalanine-methylester

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In methanol for 1h; Heating;99%
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

L-phenylalanine
63-91-2

L-phenylalanine

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

Conditions
ConditionsYield
In methanol at 20℃; for 24h;99%
methanol
67-56-1

methanol

(S)-3-amino-4-phenyl-2-butanone
52735-74-7

(S)-3-amino-4-phenyl-2-butanone

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

Conditions
ConditionsYield
With thionyl chloride at 0 - 80℃; for 4.5h;98%
(S)-methyl 2-(2,4-dinitrophenylsulfonamido)-3-phenylpropanoate
196214-22-9

(S)-methyl 2-(2,4-dinitrophenylsulfonamido)-3-phenylpropanoate

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

Conditions
ConditionsYield
Stage #1: (S)-methyl 2-(2,4-dinitrophenylsulfonamido)-3-phenylpropanoate With thiophenol In N,N-dimethyl-formamide at 20℃; for 0.25h;
Stage #2: With hydrogenchloride
96%
2-methyl-propan-1-ol
78-83-1

2-methyl-propan-1-ol

(S)-N-acetylphenylalanine
3618-96-0

(S)-N-acetylphenylalanine

A

2-methylpropyl acetate
110-19-0

2-methylpropyl acetate

B

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

Conditions
ConditionsYield
Stage #1: (S)-N-acetylphenylalanine With triphenyl phosphite; chlorine; triethylamine In tetrahydrofuran at -30℃;
Stage #2: 2-methyl-propan-1-ol In tetrahydrofuran at -30 - 20℃;
Stage #3: With water
A n/a
B 95%
methanol
67-56-1

methanol

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

Conditions
ConditionsYield
With thionyl chloride at -10 - 20℃; for 16h;95%
With thionyl chloride at 0℃;93%
With acetyl chloride at 20℃; for 0.5h;
methanol
67-56-1

methanol

N-tert-butoxycarbonyl-L-phenylalanine
13734-34-4

N-tert-butoxycarbonyl-L-phenylalanine

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

Conditions
ConditionsYield
With chloro-trimethyl-silane at 20℃; for 19h; Esterification; de-tert-butoxycarbonylation;94%
With thionyl chloride at 50℃; for 5h; Inert atmosphere;
methyl N-{[2-(trimethylsilyl)ethyl]sulfonyl}-L-phenylalaninate
106018-94-4

methyl N-{[2-(trimethylsilyl)ethyl]sulfonyl}-L-phenylalaninate

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

Conditions
ConditionsYield
With cesium fluoride In N,N-dimethyl-formamide at 95℃; for 10h;87%
(S)-methyl 2-(2-nitrophenylsulfonamido)-3-phenylpropanoate
203873-67-0

(S)-methyl 2-(2-nitrophenylsulfonamido)-3-phenylpropanoate

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

Conditions
ConditionsYield
Stage #1: (S)-methyl 2-(2-nitrophenylsulfonamido)-3-phenylpropanoate With 1,8-diazabicyclo[5.4.0]undec-7-ene; 2-hydroxyethanethiol In N,N-dimethyl-formamide at 20℃; for 0.5h;
Stage #2: With hydrogenchloride
81%
(S)-2-benzylamino-3-phenyl-propionic acid methyl ester
66399-75-5, 84028-90-0

(S)-2-benzylamino-3-phenyl-propionic acid methyl ester

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

Conditions
ConditionsYield
Stage #1: (S)-2-benzylamino-3-phenyl-propionic acid methyl ester With tert.-butylhydroperoxide; dirhodium(II) tetrakis(caprolactam) In acetonitrile at 20℃; for 16h;
Stage #2: With hydrogenchloride In diethyl ether at 20℃; for 6h;
78%
methyl (S)-3-phenyl-2-(1H-pyrrol-1-yl)propanoate
116763-08-7

methyl (S)-3-phenyl-2-(1H-pyrrol-1-yl)propanoate

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

Conditions
ConditionsYield
Stage #1: methyl (S)-3-phenyl-2-(1H-pyrrol-1-yl)propanoate With ozone In methanol at -78℃; for 2.5h; Inert atmosphere;
Stage #2: With thiourea In methanol at -78 - 0℃; for 1.5h; Inert atmosphere;
Stage #3: With hydrogenchloride In 1,4-dioxane; methanol at 0 - 20℃; for 6h; Inert atmosphere;
71%
N-formyl-L-phenylalanine
13200-85-6

N-formyl-L-phenylalanine

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

Conditions
ConditionsYield
With hydrogenchloride
methanol
67-56-1

methanol

DL-β-chloro-β-phenylalanine hydrochloride
126027-31-4

DL-β-chloro-β-phenylalanine hydrochloride

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

Conditions
ConditionsYield
Yield given. Multistep reaction;
NPS-Phe-OMe
17349-27-8

NPS-Phe-OMe

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In diethyl ether
(S)-2-{[1-[(1S,2R,5R)-5-Methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl]-meth-(E)-ylidene]-amino}-3-phenyl-propionic acid methyl ester

(S)-2-{[1-[(1S,2R,5R)-5-Methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl]-meth-(E)-ylidene]-amino}-3-phenyl-propionic acid methyl ester

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In diethyl ether at 20℃; Hydrolysis;
L-phenylalanine
63-91-2

L-phenylalanine

methyl iodide
74-88-4

methyl iodide

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

Conditions
ConditionsYield
Stage #1: L-phenylalanine With thionyl chloride
Stage #2: methyl iodide
methanol
67-56-1

methanol

Phe-Chlor
87877-11-0

Phe-Chlor

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

benzyl bromide
100-39-0

benzyl bromide

t-BuOCOCH2-X

t-BuOCOCH2-X

A

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

B

pyrrole

pyrrole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: LDA / tetrahydrofuran / -78 °C
1.2: 85 percent / tetrahydrofuran / -78 °C
2.1: aq. HCl / diethyl ether / 20 °C
View Scheme
Nps-L-Phe-OH
2688-22-4

Nps-L-Phe-OH

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 94 percent / dicyclohexylcarbodi-imide, 4-dimethylaminopyridine / 1) 0 deg C, 5 min, 2) 25 deg C, 3 h
2: HCl / diethyl ether
View Scheme
(R,S)-2-amino-3-phenylpropionamide
17193-31-6

(R,S)-2-amino-3-phenylpropionamide

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: enzymatic hydrolysis with pronase immobilized on ketonic polymer; effects of pH, substrat concentration, catalyst mass
2: 99 percent / SOCl2 / 3 h / Heating
View Scheme
methyl (2S)-2-amino-3-phenylpropanoate
2577-90-4

methyl (2S)-2-amino-3-phenylpropanoate

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In water
C10H13NO2*C30H46N2O4*ClH
1202242-83-8

C10H13NO2*C30H46N2O4*ClH

A

(6S,17S)-1,4-di[N-(S)-α-phenylethyl]-1,4-diaza-6,17-dimethyl-7,10,13,19-tetraoxacyclooctadecane
1202242-75-8

(6S,17S)-1,4-di[N-(S)-α-phenylethyl]-1,4-diaza-6,17-dimethyl-7,10,13,19-tetraoxacyclooctadecane

B

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

Conditions
ConditionsYield
In chloroform-d1; d(4)-methanol Equilibrium constant; Inert atmosphere;
C10H13NO2*C34H46N2O4*ClH
1202242-87-2

C10H13NO2*C34H46N2O4*ClH

A

(6S,17S)-1,4-di[N-(S)-α-phenylethyl]-1,4-diaza-6,17-dimethyl-11,12-benzo-7,10,13,19-tetraoxacyclooctadec-11-ene
1202242-76-9

(6S,17S)-1,4-di[N-(S)-α-phenylethyl]-1,4-diaza-6,17-dimethyl-11,12-benzo-7,10,13,19-tetraoxacyclooctadec-11-ene

B

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

Conditions
ConditionsYield
In chloroform-d1; d(4)-methanol Equilibrium constant; Inert atmosphere;
C10H13NO2*C42H54N2O6*ClH
1202242-91-8

C10H13NO2*C42H54N2O6*ClH

A

(6S,17S)-1,4-di[N-(S)-α-phenylethyl]-1,4-diaza-6,17-diphenoxymethyl-7,10,13,19-tetraoxacyclooctadecane
1202242-77-0

(6S,17S)-1,4-di[N-(S)-α-phenylethyl]-1,4-diaza-6,17-diphenoxymethyl-7,10,13,19-tetraoxacyclooctadecane

B

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

Conditions
ConditionsYield
In chloroform-d1; d(4)-methanol Equilibrium constant; Inert atmosphere;
Z-Leu-OH
2018-66-8

Z-Leu-OH

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

N-(benzyloxycarbonyl)-L-leucyl-L-phenylalanine methyl ester
10473-38-8, 16679-86-0, 120342-23-6, 4818-00-2

N-(benzyloxycarbonyl)-L-leucyl-L-phenylalanine methyl ester

Conditions
ConditionsYield
In ethyl acetate at 40℃; thermolysin, 0.05 M 2-(N-morpholino)ethanesulfonic acid - NaOH buffer pH 6.0 - 7.0, CaCl2;100%
With 4-methyl-morpholine; benzotriazol-1-ol; dicyclohexyl-carbodiimide In tetrahydrofuran at 0 - 20℃; for 21h;97%
With N-ethylmorpholine;; isobutyl chloroformate In ethyl acetate 1.) 1 h, -30 deg C, 2.) 1 h, room temperature;65%
t-Boc-L-valine
13734-41-3

t-Boc-L-valine

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

N-tert-butoxycarbonyl-L-valyl-L-phenylalanine methyl ester
20902-47-0

N-tert-butoxycarbonyl-L-valyl-L-phenylalanine methyl ester

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane at 20℃; for 24h;100%
Stage #1: t-Boc-L-valine With 2,6-dimethylpyridine; 6-chloro-3-((dimethylamino)(dimethyliminio)methyl)-1H-benzo[d][1,2,3]triazol-3-ium-1-olatehexafluorophosphate(V); 6-chloro-1-hydroxybenzotriazole In dichloromethane; N,N-dimethyl-formamide at 0℃; for 0.166667h;
Stage #2: methyl (2S)-2-amino-3-phenylpropanoate hydrochloride With 2,6-dimethylpyridine In dichloromethane; N,N-dimethyl-formamide
97%
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In tetrahydrofuran; acetonitrile at 20℃; for 3h;89%
N-(tert-butyloxycarbonyl)-L-isoleucine
13139-16-7

N-(tert-butyloxycarbonyl)-L-isoleucine

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

(S)-methyl 2-((2S,3S)-2-((tert-butoxycarbonyl)amino)-3-methylpentanamido)-3-phenylpropanoate
97641-59-3

(S)-methyl 2-((2S,3S)-2-((tert-butoxycarbonyl)amino)-3-methylpentanamido)-3-phenylpropanoate

Conditions
ConditionsYield
Stage #1: N-(tert-butyloxycarbonyl)-L-isoleucine With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate at 20℃; for 0.166667h;
Stage #2: methyl (2S)-2-amino-3-phenylpropanoate hydrochloride at 20℃; for 1h;
100%
With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In acetonitrile at 0 - 20℃; for 2h;98%
Stage #1: methyl (2S)-2-amino-3-phenylpropanoate hydrochloride With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; Inert atmosphere;
Stage #2: N-(tert-butyloxycarbonyl)-L-isoleucine With benzotriazol-1-ol In dichloromethane at 0℃; for 0.25h; Inert atmosphere;
Stage #3: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0 - 20℃; for 12h; Inert atmosphere;
88%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

(S)-2-tert-butoxycarbonylamino-3-phenyl-propionic acid methyl ester
51987-73-6

(S)-2-tert-butoxycarbonylamino-3-phenyl-propionic acid methyl ester

Conditions
ConditionsYield
With triethylamine In dichloromethane for 24h; Ambient temperature;100%
With triethylamine In tetrahydrofuran at 0 - 20℃; Inert atmosphere;100%
In tetrahydrofuran; methanol at 20℃; for 4h; Inert atmosphere;99%
N-Cbz-L-Asp
1152-61-0

N-Cbz-L-Asp

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

N-benzyloxycarbonyl-L-aspartyl-L-phenylalanine methyl ester-L-phenylalanine methyl ester complex
68802-01-7

N-benzyloxycarbonyl-L-aspartyl-L-phenylalanine methyl ester-L-phenylalanine methyl ester complex

Conditions
ConditionsYield
With sodium hydroxide In water at 40℃; for 20h; immobilized thermolysin, pH 6.5;100%
BOC-ALA-HOBt
66024-53-1

BOC-ALA-HOBt

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

N-tert-butyloxycarbonylalanylphenylalanine methyl ester
2280-66-2

N-tert-butyloxycarbonylalanylphenylalanine methyl ester

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide for 0.5h;100%
methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

(R)-2-azido-3-phenylpropanoic acid
118460-00-7

(R)-2-azido-3-phenylpropanoic acid

methyl <2R,2(2S)>-2-<2-azido-1-oxo-3-phenylamino>-3-phenylpropionate

methyl <2R,2(2S)>-2-<2-azido-1-oxo-3-phenylamino>-3-phenylpropionate

Conditions
ConditionsYield
With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride100%
methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

(2S)-2-azido-3-phenylpropanoic acid
79410-35-8

(2S)-2-azido-3-phenylpropanoic acid

methyl <2R,2(2S)>-2-<2-azido-1-oxo-3-phenylamino>-3-phenylpropionate

methyl <2R,2(2S)>-2-<2-azido-1-oxo-3-phenylamino>-3-phenylpropionate

Conditions
ConditionsYield
With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide 1.) 0 deg C, 2 h; 2.) room temp., 24 h;100%
methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

N-(tert-butoxycarbonyl)-2-methyl-L-proline
103336-06-7

N-(tert-butoxycarbonyl)-2-methyl-L-proline

N-(tertbutyloxycarbonyl)-α-methyl-L-prolyl-L-phenylalanine methyl ester
103336-07-8

N-(tertbutyloxycarbonyl)-α-methyl-L-prolyl-L-phenylalanine methyl ester

Conditions
ConditionsYield
With benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide In dichloromethane Ambient temperature;100%
methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

benzaldehyde
100-52-7

benzaldehyde

(S)-2-(benzylidene-amino)-3-phenyl-propionic acid methyl ester
68870-85-9, 120408-13-1, 137693-23-3, 40216-77-1

(S)-2-(benzylidene-amino)-3-phenyl-propionic acid methyl ester

Conditions
ConditionsYield
With magnesium sulfate; triethylamine In dichloromethane100%
Stage #1: methyl (2S)-2-amino-3-phenylpropanoate hydrochloride With magnesium sulfate; triethylamine In dichloromethane at 20℃; for 0.25h; Inert atmosphere;
Stage #2: benzaldehyde In dichloromethane at 20℃; Inert atmosphere;
97%
With triethylamine In chloroform at 0 - 20℃; for 24h; Inert atmosphere; Sealed tube;96%
methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

4-methoxy-benzaldehyde
123-11-5

4-methoxy-benzaldehyde

methyl (E,S)-2-(4-methoxybenzylideneamino)-3-phenylpropionate
660838-99-3

methyl (E,S)-2-(4-methoxybenzylideneamino)-3-phenylpropionate

Conditions
ConditionsYield
With sodium carbonate In methanol for 12h; Ambient temperature;100%
With 4 A molecular sieve; titanium tetrachloride; sodium sulfate; triethylamine In dichloromethane at 20℃; for 8h;94%
With sodium hydrogencarbonate In methanol Reflux;87%
methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

N-Benzyloxycarbonyl-L-proline
1148-11-4

N-Benzyloxycarbonyl-L-proline

N-carbobenzoxy-L-prolyl-L-phenylalanine methyl ester
23631-72-3

N-carbobenzoxy-L-prolyl-L-phenylalanine methyl ester

Conditions
ConditionsYield
With N-Ethylmaleimide; benzotriazol-1-ol; dicyclohexyl-carbodiimide In tetrahydrofuran at 25℃; for 18h; pH 7.0-7.5;100%
With benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; for 19h;92%
With triethylamine; 2-Pyridon-1-yl diphenyl phosphate In N,N-dimethyl-formamide for 3h; Ambient temperature;85%
methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

CBZ-piperazinesulfonyl chloride

CBZ-piperazinesulfonyl chloride

(S)-4-<<1-(methoxycarbonyl)-2-phenylethyl>sulfamoyl>piperazine-1-carboxylic acid benzyl ester

(S)-4-<<1-(methoxycarbonyl)-2-phenylethyl>sulfamoyl>piperazine-1-carboxylic acid benzyl ester

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane for 96h; Ambient temperature;100%
methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

chloroformic acid ethyl ester
541-41-3

chloroformic acid ethyl ester

methyl (S)-2-ethyloxycarbonylamino-3-phenylpropanoate
91084-05-8

methyl (S)-2-ethyloxycarbonylamino-3-phenylpropanoate

Conditions
ConditionsYield
With sodium hydrogencarbonate In water at 0 - 20℃;100%
With triethylamine In dichloromethane at 0 - 20℃; Inert atmosphere;93%
With triethylamine In tetrahydrofuran at 0 - 20℃;87%
With sodium hydrogencarbonate for 4h; Ambient temperature; Yield given;
methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

N-[3β-hydroxy-lup-20(29)-en-28-oyl]-8-aminooctanoic acid
150841-42-2

N-[3β-hydroxy-lup-20(29)-en-28-oyl]-8-aminooctanoic acid

(S)-2-{8-[((1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Acetoxy-1-isopropenyl-5a,5b,8,8,11a-pentamethyl-icosahydro-cyclopenta[a]chrysene-3a-carbonyl)-amino]-octanoylamino}-3-phenyl-propionic acid methyl ester
174740-20-6

(S)-2-{8-[((1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Acetoxy-1-isopropenyl-5a,5b,8,8,11a-pentamethyl-icosahydro-cyclopenta[a]chrysene-3a-carbonyl)-amino]-octanoylamino}-3-phenyl-propionic acid methyl ester

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane for 15h; Ambient temperature;100%
methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

5-[tert-butoxycarbonyl-(3,5-di-tert-butylbenzyl)-amino]pentanoic acid
518033-67-5

5-[tert-butoxycarbonyl-(3,5-di-tert-butylbenzyl)-amino]pentanoic acid

2-{5-[tert-butoxycarbonyl(3,5-di-tert-butylbenzyl)amino]pentanoylamino}-3-phenylpropanoic acid methyl ester
518033-68-6

2-{5-[tert-butoxycarbonyl(3,5-di-tert-butylbenzyl)amino]pentanoylamino}-3-phenylpropanoic acid methyl ester

Conditions
ConditionsYield
Stage #1: 5-[tert-butoxycarbonyl-(3,5-di-tert-butylbenzyl)-amino]pentanoic acid With 1,1'-carbonyldiimidazole In dichloromethane for 0.333333h;
Stage #2: methyl (2S)-2-amino-3-phenylpropanoate hydrochloride With 1H-imidazole In dichloromethane at 20℃;
100%
methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

(3S,4S)-1-(4-fluorobenzoyl)-3-triisopropylsiloxy-4-difluoromethylazetidin-2-one
740802-81-7

(3S,4S)-1-(4-fluorobenzoyl)-3-triisopropylsiloxy-4-difluoromethylazetidin-2-one

[(2S,3S)-4,4-difluoro-3-(4-fluorobenzoylamino)-2-triisopropylsiloxybutanoyl]-(S)-phenylalanine methyl ester

[(2S,3S)-4,4-difluoro-3-(4-fluorobenzoylamino)-2-triisopropylsiloxybutanoyl]-(S)-phenylalanine methyl ester

Conditions
ConditionsYield
With 4-methyl-morpholine In dichloromethane at 25℃; for 12h;100%
methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

Boc-Trp-OH
13139-14-5

Boc-Trp-OH

Nα-(tert-butoxycarbonyl)-L-tryptophyl-L-phenylalanine methyl ester
72156-62-8

Nα-(tert-butoxycarbonyl)-L-tryptophyl-L-phenylalanine methyl ester

Conditions
ConditionsYield
Stage #1: methyl (2S)-2-amino-3-phenylpropanoate hydrochloride With sodium carbonate In dichloromethane; water
Stage #2: Boc-Trp-OH With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 2h;
100%
With O‑(6‑chlorobezotriazol‑1‑yl)‑N,N,N,N‑tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 16h; Inert atmosphere;99%
With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In acetonitrile at 0 - 20℃; for 2h;96%
4-(1-carboxymethyl-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-ylmethyl)imidazole-1-carboxylic acid tert-butyl ester
847665-21-8

4-(1-carboxymethyl-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-ylmethyl)imidazole-1-carboxylic acid tert-butyl ester

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

4-{1-[(1-methoxycarbonyl-2-phenylethylcarbamoyl)methyl]-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-ylmethyl}-imidazole-1-carboxylic acid tert-butyl ester
847665-23-0

4-{1-[(1-methoxycarbonyl-2-phenylethylcarbamoyl)methyl]-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-ylmethyl}-imidazole-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In N,N-dimethyl-formamide at 20℃;100%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

methyl (S)-2-[bis(tert-butoxycarbonyl) amino]-3-phenylpropanoate
154409-62-8

methyl (S)-2-[bis(tert-butoxycarbonyl) amino]-3-phenylpropanoate

Conditions
ConditionsYield
Stage #1: methyl (2S)-2-amino-3-phenylpropanoate hydrochloride With sodium carbonate In tetrahydrofuran; water at 20℃; for 2h;
Stage #2: di-tert-butyl dicarbonate With dmap In acetonitrile at 20℃; for 12h;
100%
Multi-step reaction with 2 steps
1: sodium hydrogencarbonate / water; tetrahydrofuran / 16 h / 22 °C / Inert atmosphere
2: dmap / acetonitrile / 16 h / 22 °C / Inert atmosphere
View Scheme
2-pyrazylcarboxylic acid
98-97-5

2-pyrazylcarboxylic acid

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

N-(2-pyrazinylcarbonyl)-L-phenylalanine methyl ester
73058-37-4

N-(2-pyrazinylcarbonyl)-L-phenylalanine methyl ester

Conditions
ConditionsYield
With 4-methyl-morpholine; 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide In dichloromethane; acetonitrile at -15 - 25℃; for 5h; Product distribution / selectivity;100%
With 4-methyl-morpholine; benzotriazol-1-ol; dicyclohexyl-carbodiimide In tetrahydrofuran at 0℃; for 2.66667h;98%
Stage #1: 2-pyrazylcarboxylic acid With benzotriazol-1-ol; dicyclohexyl-carbodiimide In tetrahydrofuran at 0℃; for 0.666667h;
Stage #2: methyl (2S)-2-amino-3-phenylpropanoate hydrochloride With 4-methyl-morpholine In tetrahydrofuran for 12h;
98%
sodium acetate
127-09-3

sodium acetate

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

(S)-N-acetylphenylalanine
3618-96-0

(S)-N-acetylphenylalanine

Conditions
ConditionsYield
With C16H20N5O2(1+)*Cl(1-) In dichloromethane at 20℃; for 0.166667h;100%
With 4-methyl-morpholine In methanol at 20℃; for 24h;90%
(2S-trans)-3-butyl-oxirane carboxylic acid.dicyclohexylammonium salt
387400-58-0

(2S-trans)-3-butyl-oxirane carboxylic acid.dicyclohexylammonium salt

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

pivaloyl chloride
3282-30-2

pivaloyl chloride

(2S-trans)-N-[(2S)-1-methoxy-1-oxo-3-phenyl-2-propyl]-3-butyloxiranecarboxamide

(2S-trans)-N-[(2S)-1-methoxy-1-oxo-3-phenyl-2-propyl]-3-butyloxiranecarboxamide

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran; ethyl acetate100%
(R)-3-benzyloxycarbonyl-2-pentylpropanoic acid
611212-55-6

(R)-3-benzyloxycarbonyl-2-pentylpropanoic acid

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

N-[(R)-3-benzyloxycarbonyl-2-pentylpropanoyl]-L-phenylalanine methyl ester
1035610-05-9

N-[(R)-3-benzyloxycarbonyl-2-pentylpropanoyl]-L-phenylalanine methyl ester

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 2h;100%
carbon monoxide
201230-82-2

carbon monoxide

17-iodo-5α-androst-16-ene
26313-26-8

17-iodo-5α-androst-16-ene

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

C30H41NO3
840474-62-6

C30H41NO3

Conditions
ConditionsYield
With palladium diacetate; triethylamine; triphenylphosphine at 100℃; for 8h;100%
O-methyl-N-tert-butoxycarbonyl-L-tyrosine
53267-93-9

O-methyl-N-tert-butoxycarbonyl-L-tyrosine

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

(S)-methyl 2-((S)-2-((tert-butoxycarbonyl)amino)-3-(4-methoxyphenyl)propanamido)-3-phenylpropanoate

(S)-methyl 2-((S)-2-((tert-butoxycarbonyl)amino)-3-(4-methoxyphenyl)propanamido)-3-phenylpropanoate

Conditions
ConditionsYield
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In dichloromethane for 15h;100%
tert-butyl isothiocyanate
590-42-1

tert-butyl isothiocyanate

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

methyl [2-(3-tert-butyl-1-thioureido)]-3-phenylpropionate

methyl [2-(3-tert-butyl-1-thioureido)]-3-phenylpropionate

Conditions
ConditionsYield
Stage #1: methyl (2S)-2-amino-3-phenylpropanoate hydrochloride With triethylamine In tetrahydrofuran for 0.0833333h;
Stage #2: tert-butyl isothiocyanate In tetrahydrofuran for 1h; Heating / reflux;
100%

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