(S)-2-acetoxypropionic acid
(S)-2-acetoxypropanoyl chloride
Conditions | Yield |
---|---|
With thionyl chloride at 50℃; for 2h; | 93.7% |
With thionyl chloride at 20℃; Chlorination; | 31% |
With thionyl chloride |
Conditions | Yield |
---|---|
With hydrogenchloride; thionyl chloride In diethyl ether | 64% |
sodium L-lactate
(S)-2-acetoxypropanoyl chloride
(S)-2-acetoxypropanoyl chloride
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: hydrogenchloride / water / 0.25 h / 20 - 40 °C 2: thionyl chloride / 1,2-dichloro-ethane / 7 h / 40 °C View Scheme |
oxalyl dichloride
L-Lactic acid
acetyl chloride
(S)-2-acetoxypropanoyl chloride
Conditions | Yield |
---|---|
In dichloromethane |
Conditions | Yield |
---|---|
Stage #1: L-Lactic acid; acetyl chloride at 20℃; Schlenk technique; Inert atmosphere; Stage #2: With thionyl chloride In N,N-dimethyl-formamide at 20℃; Schlenk technique; Inert atmosphere; |
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; for 1h; Inert atmosphere; | 100% |
(S)-2-acetoxypropanoyl chloride
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; for 1.5h; | 100% |
ethyl (1R,2S)-2-hydroxycyclohexane-1-carboxylate
(S)-2-acetoxypropanoyl chloride
Conditions | Yield |
---|---|
With pyridine In diethyl ether at 4℃; for 20h; Acylation; | 99% |
(S)-2-acetoxypropanoyl chloride
Conditions | Yield |
---|---|
With dmap; triethylamine In dichloromethane at 0℃; for 0.416667h; | 99% |
(S)-2-acetoxypropanoyl chloride
6-amino-5-fluoroindolin-2-one
acetic acid 1-(5-fluoro-2-oxo-2,3-dihydro-1H-indol-6-ylcarbamoyl)-ethyl ester
Conditions | Yield |
---|---|
With piperidine In tetrahydrofuran at -40 - 20℃; | 99% |
(S)-2-acetoxypropanoyl chloride
6-amino-5-fluoroindolin-2-one
(S)-acetic acid 1-(5-fluoro-2-oxo-2,3-dihydro-1H-indol-6-ylcarbamoyl)-ethyl ester
Conditions | Yield |
---|---|
With piperidine In tetrahydrofuran at -40 - 20℃; | 99% |
(S)-2-acetoxypropanoyl chloride
3-amino-4-hydroxytoluene
(2S)-1-(2-hydroxy-5-methylphenylamino)-1-oxopropan-2-yl acetate
Conditions | Yield |
---|---|
With 1H-imidazole In dichloromethane; acetone at 10 - 20℃; | 97% |
(S)-2-acetoxypropanoyl chloride
(S)-3-fluoro-4-nitrophenylalanine methyl ester
Conditions | Yield |
---|---|
With dmap; triethylamine In dichloromethane for 1h; Ambient temperature; | 96% |
With dmap; triethylamine In dichloromethane Ambient temperature; Yield given; |
(S)-2-acetoxypropanoyl chloride
(R)-(3-Allyloxy-phenyl)-amino-acetic acid methyl ester
Conditions | Yield |
---|---|
With dmap; triethylamine In dichloromethane at 0℃; for 1h; | 96% |
2-methyltetrahydrofuran
(S)-2-acetoxypropanoyl chloride
Conditions | Yield |
---|---|
With bismuth(III) chloride In dichloromethane at 20℃; | 96% |
4-Chlorodeacetylcolchicine
(S)-2-acetoxypropanoyl chloride
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; Cooling with ice; Inert atmosphere; | 95% |
(S)-2-acetoxypropanoyl chloride
5-amino-2,4,6-triiodoisophthalic acid dichloride
S-(-)-5-[[2-(acetyloxy)-1-oxopropyl]amino]-2,4,6-triiodo-1,3-benzenedicarboxylic acid dichloride
Conditions | Yield |
---|---|
In N,N-dimethyl acetamide at 0 - 20℃; Inert atmosphere; | 92.3% |
In N,N-dimethyl acetamide at 0 - 20℃; for 38h; Inert atmosphere; | 91.4% |
Stage #1: (S)-2-acetoxypropanoyl chloride In N,N-dimethyl acetamide at -2 - 0℃; for 1h; Stage #2: 5-amino-2,4,6-triiodoisophthalic acid dichloride; metanol at 12℃; for 6h; Stage #3: With 2-ethoxy-ethanol more than 3 stages; | 90% |
Stage #1: (S)-2-acetoxypropanoyl chloride In N,N-dimethyl acetamide at -2 - 0℃; for 1h; Stage #2: 5-amino-2,4,6-triiodoisophthalic acid dichloride; metanol In N,N-dimethyl acetamide at 12℃; for 6h; Stage #3: With 2-ethoxy-ethanol more than 3 stages; | 89% |
With N,N-dimethylacetamide hydrochloride In ISOPROPYLAMIDE at 10 - 25℃; |
(S)-1-phenyl-ethylamine
(S)-2-acetoxypropanoyl chloride
(S)-2-Acetoxy-N-<(S)-α-methylbenzyl>propionamide
Conditions | Yield |
---|---|
With pyridine In dichloromethane for 1h; | 92% |
With pyridine In dichloromethane at 0℃; for 1h; | 86% |
(S)-3-(9-methylthio-6-oxo-2,3,3a,4-tetrahydro-1H,6H-5,8,10,10b-tetraazabenzo[e]azulen-5-yl)benzoic hydrazide
(S)-2-acetoxypropanoyl chloride
(S)-3-(9-methylthio-6-oxo-2,3,3a,4-tetrahydro-1H,6H-5,8,10,10b-tetraazabenzo[e]azulen-5-yl)benzoic acid-N'-(2S)-acetoxypropionyl hydrazide
Conditions | Yield |
---|---|
With pyridine In dichloromethane at 0℃; for 1h; | 92% |
methyl 2-Amino-5-trifluoromethylbenzoate
(S)-2-acetoxypropanoyl chloride
Conditions | Yield |
---|---|
In diethyl ether at -10 - 20℃; for 3h; | 92% |
(S)-2-acetoxypropanoyl chloride
diethylamine
2-(S)-acetylpropionyl-N,N-diethyl amide
Conditions | Yield |
---|---|
With triethylamine In dichloromethane for 12h; Ambient temperature; | 91% |
2-(1,1-dimethylethyl)-benzenamine
(S)-2-acetoxypropanoyl chloride
(2S)-N-(2-tert-butylphenyl)-2-acetoxypropionamide
Conditions | Yield |
---|---|
With pyridine at 25℃; for 3h; | 91% |
3-(diphenylphosphinoyl)-2-iodo-phenol
(S)-2-acetoxypropanoyl chloride
(S)-2-Acetoxy-propionic acid 3-(diphenyl-phosphinoyl)-2-iodo-phenyl ester
Conditions | Yield |
---|---|
With TEA In dichloromethane at 20℃; for 1h; | 91% |
(S)-2-acetoxypropanoyl chloride
12(R)-benzoyloxy-5(S)-hydroxy icosa-8(E,Z),10(E)-diene 6,14-diynoate de methyle
Benzoic acid (2E,4E)-(1R,8S)-8-((R)-2-acetoxy-propionyloxy)-11-methoxycarbonyl-1-oct-2-ynyl-undeca-2,4-dien-6-ynyl ester
Conditions | Yield |
---|---|
With pyridine In diethyl ether | 90% |
DL-alanine ethyl ester hydrochloride
(S)-2-acetoxypropanoyl chloride
Conditions | Yield |
---|---|
With pyridine In dichloromethane for 1h; | 90% |
5(R)-Isoxazol-3-yloxymethyl-3-(4-(1,2,5,6-tetrahydropyrid-4-yl)-3-fluorophenyl)oxazolidin-2-one
(S)-2-acetoxypropanoyl chloride
N-ethyl-N,N-diisopropylamine
Conditions | Yield |
---|---|
In methanol; dichloromethane | 90% |
(S)-2-acetoxypropanoyl chloride
2-carbomethoxyaniline
(S)-methyl 2-(2-acetoxypropanamido)benzoate
Conditions | Yield |
---|---|
In diethyl ether at -10 - 20℃; for 3h; | 89.9% |
In diethyl ether Yield given; | |
In diethyl ether at 0℃; Inert atmosphere; Schlenk technique; |
(S)-2-acetoxypropanoyl chloride
Conditions | Yield |
---|---|
water In ISOPROPYLAMIDE at -2 - 20℃; for 21 - 23h; | 89% |
[Mo(hydridotris(pyrazolyl)borate)(CO)2(η3-C6H8OTBS)]
(S)-2-acetoxypropanoyl chloride
Conditions | Yield |
---|---|
With [(C4H9)4N][SiF2(C6H5)3] In dichloromethane addn. of tetrabutylammonium salt to CH2Cl2 soln. of molybdenum compd., stirring for 30 min at room temp., addn. of acetoxypropionyl chloride, stirring at room temp. for 10 min; concg., flash chromy. (silica gel, hexanes/ethyl acetate (4:1)), recrystn. (CH2Cl2/hexanes), NMR and MS; | 89% |
(S)-2-acetoxypropanoyl chloride
L-tryptophan methyl ester
Conditions | Yield |
---|---|
With triethylamine In 1,2-dichloro-ethane | 88.6% |
(S)-2-acetoxypropanoyl chloride
(S)-2-Acetoxypropanamide
Conditions | Yield |
---|---|
With ammonia In dichloromethane at 20℃; for 1h; | 88% |
With dichloromethane; ammonia | |
Yield given; |
(R)-1-phenyl-ethyl-amine
(S)-2-acetoxypropanoyl chloride
(S)-2-Acetoxy-N-<(R)-α-methylbenzyl>propionamide
Conditions | Yield |
---|---|
With pyridine In dichloromethane at 0℃; for 1h; | 88% |
With pyridine In dichloromethane for 1h; | 82% |
(S)-2-acetoxypropanoyl chloride
(S)-3-Amino-2-(1-tert-butyldimethylsilyloxy-2-methylpropyl)quinazolin-4(3H)-one
3-(S)-2-Acetoxypropanoylamino-2-[(S)-1-tert-butyldimethylsilyloxy-2-methylpropyl]quinazolin-4(3H)-one
Conditions | Yield |
---|---|
With pyridine In dichloromethane at 20℃; for 24h; | 88% |
Molecular Structure of Propanoyl chloride,2-(acetyloxy)-, (2S)- (CAS No.36394-75-9):
Molecular Formula: C5H7ClO3
Molecular Weight: 150.56
CAS No: 36394-75-9
Density: 1.189 g/cm3
Boiling point: 50 ºC (5 mmHg)
Refractive index: 1.423
Flash point: 113 ºC
Hazard Codes: C
Risk Statements: 34
R34:Causes burns.
Safety Statements: 26-36/37/39-45
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 3265 8/PG 2
WGK Germany: 3
F: 10-21
HazardClass: 8
PackingGroup: III
Propanoyl chloride,2-(acetyloxy)-, (2S)- (CAS No.36394-75-9), its synonyms are (S)-(-)-O-Acetyllactoyl chloride ; (S)-(-)-2-Acetoxypropionyl chloride ; (S)-2-Acetoxypropionyl chloride ; S-Acetoxypropionyl chloride ; O-Acetyl-l-lactyl chloride ; 2-Acetoxy propionyl chloride;L-(-)-2-Acetoxypropionyl chloride .
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View