Product Name

  • Name

    2-METHOXYETHYLAMINE

  • EINECS 203-712-1
  • CAS No. 109-85-3
  • Article Data68
  • CAS DataBase
  • Density 0.853 g/cm3
  • Solubility Completely miscible in water
  • Melting Point -82 °C
  • Formula C3H9NO
  • Boiling Point 94.999 °C at 760 mmHg
  • Molecular Weight 75.1106
  • Flash Point 9.444 °C
  • Transport Information
  • Appearance clear colorless liquid
  • Safety 16-26-36/37/39-45
  • Risk Codes 11-34
  • Molecular Structure Molecular Structure of 109-85-3 (2-METHOXYETHYLAMINE)
  • Hazard Symbols FlammableF,CorrosiveC
  • Synonyms Ethylamine,2-methoxy- (6CI,7CI,8CI);1-Amino-2-methoxyethane;1-Methoxy-2-aminoethane;2-(Methyloxy)ethanamine;2-Aminoethyl methyl ether;2-Methoxy-1-aminoethane;2-Methoxy-1-ethanamine;2-Methoxyethanamine;2-Methoxyethylamine;N-(2-Methoxyethyl)amine;b-Methoxyethylamine;
  • PSA 35.25000
  • LogP 0.29180

Synthetic route

N,N'-Di(2-methoxyethyl)thioharnstoff
1119-13-7

N,N'-Di(2-methoxyethyl)thioharnstoff

2-methoxyethylamine
109-85-3

2-methoxyethylamine

Conditions
ConditionsYield
With dipotassium peroxodisulfate In water; acetonitrile at 80℃; for 6h; Temperature; Reagent/catalyst; Solvent;83.5%
2-(2-Methoxy-ethoxy)-isoindole-1,3-dione
54149-18-7

2-(2-Methoxy-ethoxy)-isoindole-1,3-dione

2-methoxyethylamine
109-85-3

2-methoxyethylamine

Conditions
ConditionsYield
With methylhydrazine In dichloromethane at -10℃; for 2h;77%
(2-methoxyethyl)amine hydrochloride
18600-40-3

(2-methoxyethyl)amine hydrochloride

2-methoxyethylamine
109-85-3

2-methoxyethylamine

Conditions
ConditionsYield
With sodium hydroxide In dichloromethane at 20 - 25℃; for 1h;53.6%
ethylene glycol
107-21-1

ethylene glycol

A

morpholine
110-91-8

morpholine

B

4-methyl-morpholine
109-02-4

4-methyl-morpholine

C

N-ethylmorpholine;
100-74-3

N-ethylmorpholine;

D

2-methoxy-ethanol
109-86-4

2-methoxy-ethanol

E

2-methoxyethylamine
109-85-3

2-methoxyethylamine

Conditions
ConditionsYield
With ammonia; hydrogen at 200℃; for 0.00175h; Product distribution; 190 - 260 deg C;A 46%
B 2.1 % Chromat.
C 1.4 % Chromat.
D 0.7 % Chromat.
E 0.6 % Chromat.
methanol
67-56-1

methanol

(2-amino-ethyl)-nitroso-amidosulfuric acid
861555-02-4

(2-amino-ethyl)-nitroso-amidosulfuric acid

2-methoxyethylamine
109-85-3

2-methoxyethylamine

Conditions
ConditionsYield
reagiert analog mit Alkohol und Propylalkohol;
2-(2-methoxyethyl)isoindoline-1,3-dione
41081-97-4

2-(2-methoxyethyl)isoindoline-1,3-dione

2-methoxyethylamine
109-85-3

2-methoxyethylamine

Conditions
ConditionsYield
With sodium hydroxide
With potassium hydroxide In water
1-methoxy-2-nitroethane
35461-44-0

1-methoxy-2-nitroethane

2-methoxyethylamine
109-85-3

2-methoxyethylamine

Conditions
ConditionsYield
With ethanol; platinum at 20℃; under 73550.8 Torr; Hydrogenation;
2-methoxy-ethanol
109-86-4

2-methoxy-ethanol

2-methoxyethylamine
109-85-3

2-methoxyethylamine

Conditions
ConditionsYield
With aluminum oxide; ammonia at 200 - 250℃;
With ammonia; nickel at 200 - 250℃;
With ammonia; hydrogen at 250℃; under 3750.38 Torr; for 2h; Reagent/catalyst;
2-methoxyacetonitrile
1738-36-9

2-methoxyacetonitrile

2-methoxyethylamine
109-85-3

2-methoxyethylamine

Conditions
ConditionsYield
With nickel Hydrogenation;
N-(2-methoxy-ethyl)-2,4-dinitro-aniline
23920-12-9

N-(2-methoxy-ethyl)-2,4-dinitro-aniline

2-methoxyethylamine
109-85-3

2-methoxyethylamine

Conditions
ConditionsYield
With sodium hydroxide
(2-Methoxy-ethyl)-[2-methyl-prop-(Z)-ylidene]-amine
22483-14-3

(2-Methoxy-ethyl)-[2-methyl-prop-(Z)-ylidene]-amine

2-methoxyethylamine
109-85-3

2-methoxyethylamine

Conditions
ConditionsYield
In water; benzonitrile Equilibrium constant;
3-Hydroxy-2-[(2-methoxy-ethylamino)-phenyl-methyl]-inden-1-one

3-Hydroxy-2-[(2-methoxy-ethylamino)-phenyl-methyl]-inden-1-one

A

2-methoxyethylamine
109-85-3

2-methoxyethylamine

B

2-benzylidene-indan-1,3-dione
5381-33-9

2-benzylidene-indan-1,3-dione

Conditions
ConditionsYield
With potassium chloride In water; dimethyl sulfoxide at 20℃; Rate constant; Equilibrium constant;
C13H16NO3(1-)*H(1+)

C13H16NO3(1-)*H(1+)

A

benzylidenemalonaldehyde
82700-43-4

benzylidenemalonaldehyde

B

2-methoxyethylamine
109-85-3

2-methoxyethylamine

Conditions
ConditionsYield
In water; N,N-dimethyl-formamide at 20℃; Equilibrium constant; Rate constant;
(2-methoxyethyl)ammonium ion

(2-methoxyethyl)ammonium ion

C22H15N6O12(1-)

C22H15N6O12(1-)

A

tris(5-methyl-2,4-dinitrophenyl)methane
144432-14-4

tris(5-methyl-2,4-dinitrophenyl)methane

B

2-methoxyethylamine
109-85-3

2-methoxyethylamine

Conditions
ConditionsYield
In water; dimethyl sulfoxide at 25℃; Rate constant;
(2-methoxyethyl)ammonium ion

(2-methoxyethyl)ammonium ion

C25H21N6O12(1-)

C25H21N6O12(1-)

A

tris(3,5-dimethyl-2,4-dinitrophenyl)methane
144432-15-5

tris(3,5-dimethyl-2,4-dinitrophenyl)methane

B

2-methoxyethylamine
109-85-3

2-methoxyethylamine

Conditions
ConditionsYield
In water; dimethyl sulfoxide at 25℃; Rate constant;
1-azido-2-methoxy-ethane
80894-21-9

1-azido-2-methoxy-ethane

2-methoxyethylamine
109-85-3

2-methoxyethylamine

Conditions
ConditionsYield
With triphenylphosphine 1.) THF, RT, 12 h, 2.) hydrolysis, RT, 12 h; Multistep reaction;
(1S,2R,4R,6S)-6-Hydroxy-bicyclo[2.2.1]heptane-2-carboxylic acid (2-methoxy-ethyl)-amide
74158-00-2

(1S,2R,4R,6S)-6-Hydroxy-bicyclo[2.2.1]heptane-2-carboxylic acid (2-methoxy-ethyl)-amide

endo-6-hydroxybicyclo<2.2.1>heptane-endo-2-carboxylic acid lactone
6712-12-5

endo-6-hydroxybicyclo<2.2.1>heptane-endo-2-carboxylic acid lactone

B

2-methoxyethylamine
109-85-3

2-methoxyethylamine

Conditions
ConditionsYield
In methanol; water at 30℃; Rate constant;
ethanolamine
141-43-5

ethanolamine

dimethyl sulfate
77-78-1

dimethyl sulfate

A

N-methyl-N-(2-methoxyethyl)amine
38256-93-8

N-methyl-N-(2-methoxyethyl)amine

B

N,N-dimethyl-2-methoxyethylamine
3030-44-2

N,N-dimethyl-2-methoxyethylamine

C

2-methoxyethylamine
109-85-3

2-methoxyethylamine

Conditions
ConditionsYield
With sodium hydride 1.) THF, room temp., 1 h; 2.) room temp., 1 h; Yield given. Multistep reaction;
(2-Methoxy-ethyl)-thiocarbamic acid; compound with triethyl-amine

(2-Methoxy-ethyl)-thiocarbamic acid; compound with triethyl-amine

A

carbon oxide sulfide
463-58-1

carbon oxide sulfide

B

2-methoxyethylamine
109-85-3

2-methoxyethylamine

Conditions
ConditionsYield
With phosphate buffer In water at 25℃; Mechanism; Rate constant; general acid catalysis;
N-(o-methoxybenzylidene)-2-methoxyethylamine
93549-60-1

N-(o-methoxybenzylidene)-2-methoxyethylamine

A

ortho-anisaldehyde
135-02-4

ortho-anisaldehyde

B

2-methoxyethylamine
109-85-3

2-methoxyethylamine

Conditions
ConditionsYield
With potassium chloride; 2-methoxyethylamine In water at 30℃; Rate constant; other amines, var. pH;
(1R,2S,3R,4S)-3-(2-Methoxy-ethylcarbamoyl)-bicyclo[2.2.1]hept-5-ene-2-carboxylic acid
93630-42-3

(1R,2S,3R,4S)-3-(2-Methoxy-ethylcarbamoyl)-bicyclo[2.2.1]hept-5-ene-2-carboxylic acid

A

2-methoxyethylamine
109-85-3

2-methoxyethylamine

B

3,6-endomethylene-1,2,3,6-tetrahydrophthalic anhydride
129-64-6

3,6-endomethylene-1,2,3,6-tetrahydrophthalic anhydride

Conditions
ConditionsYield
With water at 38℃; Rate constant;
(1R,7S)-5-Hydroxy-5-(2-methoxy-ethylamino)-4-oxa-tricyclo[5.2.1.02,6]dec-8-en-3-one

(1R,7S)-5-Hydroxy-5-(2-methoxy-ethylamino)-4-oxa-tricyclo[5.2.1.02,6]dec-8-en-3-one

A

2-methoxyethylamine
109-85-3

2-methoxyethylamine

B

3,6-endomethylene-1,2,3,6-tetrahydrophthalic anhydride
129-64-6

3,6-endomethylene-1,2,3,6-tetrahydrophthalic anhydride

Conditions
ConditionsYield
With water at 38℃; Rate constant;
C5H13NOS*ClH
97732-02-0

C5H13NOS*ClH

A

dimethylsulfide
75-18-3

dimethylsulfide

B

2-methoxyethylamine
109-85-3

2-methoxyethylamine

Conditions
ConditionsYield
With iodide; hydrogen cation In water at 25℃; Rate constant; pH dependence (pH = 0.5-3.0), μ = 1.0 with KCl;
acrylonitrile
107-13-1

acrylonitrile

2-methoxyethylamine
109-85-3

2-methoxyethylamine

N,N-bis(2-cyanoethyl)-2-methoxyethylamine
449165-43-9

N,N-bis(2-cyanoethyl)-2-methoxyethylamine

Conditions
ConditionsYield
In methanol for 48h; Heating;100%
3,16α-diacetoxy-1,3,5(10)-estratrien-17-one
1247-71-8

3,16α-diacetoxy-1,3,5(10)-estratrien-17-one

2-methoxyethylamine
109-85-3

2-methoxyethylamine

17-(2-methoxyethylimino)estra-1,3,5(10)-triene-3,16α-diol
137437-73-1

17-(2-methoxyethylimino)estra-1,3,5(10)-triene-3,16α-diol

Conditions
ConditionsYield
for 3h; Ambient temperature;100%
BOC-glycine
4530-20-5

BOC-glycine

anthranilic acid
118-92-3

anthranilic acid

2-methoxyethylamine
109-85-3

2-methoxyethylamine

2-aminomethyl-3-(2-methoxyethyl)-3H-quinazolin-4-one

2-aminomethyl-3-(2-methoxyethyl)-3H-quinazolin-4-one

Conditions
ConditionsYield
Stage #1: BOC-glycine; anthranilic acid With pyridine; triphenyl phosphite at 150℃; for 0.166667h; microwave irradiation;
Stage #2: 2-methoxyethylamine at 220℃; for 0.0666667h; microwave irradiation;
100%
BOC-glycine
4530-20-5

BOC-glycine

anthranilic acid
118-92-3

anthranilic acid

2-methoxyethylamine
109-85-3

2-methoxyethylamine

[3-(2-methoxyethyl)-4-oxo-3,4-dihydroquinazolin-2-yl-methyl]carbamic acid tert-butyl ester

[3-(2-methoxyethyl)-4-oxo-3,4-dihydroquinazolin-2-yl-methyl]carbamic acid tert-butyl ester

Conditions
ConditionsYield
Stage #1: BOC-glycine; anthranilic acid With pyridine; triphenyl phosphite at 150℃; for 0.166667h; microwave irradiation;
Stage #2: 2-methoxyethylamine at 180℃; for 0.05h; microwave irradiation;
100%
5-Bromo-3-[6-chloro-2-(2-methoxy-ethyl)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]-1,3-dihydro-indol-2-one
959432-07-6

5-Bromo-3-[6-chloro-2-(2-methoxy-ethyl)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]-1,3-dihydro-indol-2-one

2-methoxyethylamine
109-85-3

2-methoxyethylamine

5-Bromo-3-[2-(2-methoxy-ethyl)-6-(2-methoxy-ethylamino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]-1,3-dihydro-indol-2-one

5-Bromo-3-[2-(2-methoxy-ethyl)-6-(2-methoxy-ethylamino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
100%
ethyl trifluoroacetate,
383-63-1

ethyl trifluoroacetate,

2-methoxyethylamine
109-85-3

2-methoxyethylamine

N-(2-methoxyethyl)trifluoroacetamide
166252-93-3

N-(2-methoxyethyl)trifluoroacetamide

Conditions
ConditionsYield
In diethyl ether for 24h; cooling;100%
4-iodobenzenesulfonyl chloride
98-61-3

4-iodobenzenesulfonyl chloride

2-methoxyethylamine
109-85-3

2-methoxyethylamine

4-iodo-N-[2-(methyloxy)ethyl]benzenesulfonamide
403792-77-8

4-iodo-N-[2-(methyloxy)ethyl]benzenesulfonamide

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃; for 1h;100%
With triethylamine In dichloromethane at 0 - 20℃; for 1h;100%
2-(3-nitro-4-fluorophenyl)-5-phenylbenzoxazole
599202-33-2

2-(3-nitro-4-fluorophenyl)-5-phenylbenzoxazole

2-methoxyethylamine
109-85-3

2-methoxyethylamine

2-[3-nitro-4-(2-methoxyethylamino)phenyl]-5-phenylbenzoxazole
599202-40-1

2-[3-nitro-4-(2-methoxyethylamino)phenyl]-5-phenylbenzoxazole

Conditions
ConditionsYield
at 20℃; for 0.25h;100%
3-methoxy-5-nitrobenzoic acid
78238-12-7

3-methoxy-5-nitrobenzoic acid

2-methoxyethylamine
109-85-3

2-methoxyethylamine

3-methoxy-N-(2-methoxyethyl)-5-nitrobenzamide
1050514-17-4

3-methoxy-N-(2-methoxyethyl)-5-nitrobenzamide

Conditions
ConditionsYield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 2h;100%
4-(4-chloro-2-nitrophenoxy)benzoyl chloride
943617-67-2

4-(4-chloro-2-nitrophenoxy)benzoyl chloride

2-methoxyethylamine
109-85-3

2-methoxyethylamine

4-(4-chloro-2-nitrophenoxy)-N-(2-methoxyethyl)benzamide
943617-69-4

4-(4-chloro-2-nitrophenoxy)-N-(2-methoxyethyl)benzamide

Conditions
ConditionsYield
In 1,2-dichloro-ethane for 12h;100%
10-(8'-isothiocyanato-3',6'-dioxaoct-1'-yl)-7,8-dimethylbenzo[g]pteridine-2,4-dione
1020267-12-2

10-(8'-isothiocyanato-3',6'-dioxaoct-1'-yl)-7,8-dimethylbenzo[g]pteridine-2,4-dione

2-methoxyethylamine
109-85-3

2-methoxyethylamine

10-(9',11'-diaza-3',6',14'-trioxa-10'-thioxopentadec-1'-yl)-7,8-dimethylbenzo[g]pteridine-2,4-dione
1020267-21-3

10-(9',11'-diaza-3',6',14'-trioxa-10'-thioxopentadec-1'-yl)-7,8-dimethylbenzo[g]pteridine-2,4-dione

Conditions
ConditionsYield
With triethylamine In chloroform for 2.5h; Reflux;100%
2-(7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridin-2-yl)-1-methyl-1H-imidazole-5-carbaldehyde
1127329-22-9

2-(7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridin-2-yl)-1-methyl-1H-imidazole-5-carbaldehyde

2-methoxyethylamine
109-85-3

2-methoxyethylamine

N-((2-(7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridin-2-yl)-1-methyl-1H-imidazol-5-yl)methyl)-2-methoxyethanamine
1127329-23-0

N-((2-(7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridin-2-yl)-1-methyl-1H-imidazol-5-yl)methyl)-2-methoxyethanamine

Conditions
ConditionsYield
Stage #1: 2-(7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridin-2-yl)-1-methyl-1H-imidazole-5-carbaldehyde; 2-methoxyethylamine With sodium tris(acetoxy)borohydride; acetic acid In dichloromethane at 20℃; for 24h;
Stage #2: With water; sodium hydrogencarbonate In dichloromethane
100%
Stage #1: 2-(7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridin-2-yl)-1-methyl-1H-imidazole-5-carbaldehyde; 2-methoxyethylamine With sodium tris(acetoxy)borohydride; acetic acid In dichloromethane at 20℃; for 24h;
Stage #2: With sodium hydrogencarbonate In dichloromethane; water
C7H6ClN3O4
1203572-07-9

C7H6ClN3O4

2-methoxyethylamine
109-85-3

2-methoxyethylamine

C10H14N4O5
1203572-11-5

C10H14N4O5

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane100%
thiophene-2-carbaldehyde
98-03-3

thiophene-2-carbaldehyde

2-methoxyethylamine
109-85-3

2-methoxyethylamine

2-methoxy-N-(thiophen-2-ylmethylene)ethanamine
105387-30-2

2-methoxy-N-(thiophen-2-ylmethylene)ethanamine

Conditions
ConditionsYield
at 60℃; for 6h; Inert atmosphere;100%
With acetic acid In methanol at 25℃; for 4h;
di(2,4,6-tri-O-acetyl-3-deoxy-3-(4-(methoxycarbonyl)-1H-1,2,3-triazol-1-yl)-β-D-galactopyranosyl)sulfane
869957-51-7

di(2,4,6-tri-O-acetyl-3-deoxy-3-(4-(methoxycarbonyl)-1H-1,2,3-triazol-1-yl)-β-D-galactopyranosyl)sulfane

2-methoxyethylamine
109-85-3

2-methoxyethylamine

di(3-deoxy-3-(4-((2-methoxyethylamino)carbonyl)-1H-1,2,3-triazol-1-yl)-β-D-galactopyranosyl)sulfane
1242965-45-2

di(3-deoxy-3-(4-((2-methoxyethylamino)carbonyl)-1H-1,2,3-triazol-1-yl)-β-D-galactopyranosyl)sulfane

Conditions
ConditionsYield
With methanol for 28h;100%
ortho-nitrofluorobenzene
1493-27-2

ortho-nitrofluorobenzene

2-methoxyethylamine
109-85-3

2-methoxyethylamine

[2-(methyloxy)ethyl](2-nitrophenyl)amine
56436-24-9

[2-(methyloxy)ethyl](2-nitrophenyl)amine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In ethanol at 150℃; for 0.316667h; Sealed vial;100%
In ethanol at 20℃;
In N,N-dimethyl-formamide at 20℃;
In dichloromethane at 20℃; for 8h; Inert atmosphere;
In dichloromethane for 6h; Inert atmosphere;
2-[4-[(2-chloro-4,4-difluoro-spiro[5H-thieno[2,3-c]pyran-7,4'-piperidine]-1'-yl)methyl]-3-methyl-pyrazol-1-yl]-3-fluoro-benzaldehyde
1307314-58-4

2-[4-[(2-chloro-4,4-difluoro-spiro[5H-thieno[2,3-c]pyran-7,4'-piperidine]-1'-yl)methyl]-3-methyl-pyrazol-1-yl]-3-fluoro-benzaldehyde

2-methoxyethylamine
109-85-3

2-methoxyethylamine

N-(2-(4-((2'-chloro-4',4'-difluoro-4',5'-dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran]-1-yl)methyl)-3-methyl-1H-pyrazol-1-yl)-3-fluorobenzylidene)-2-methoxyethanamine
1307314-59-5

N-(2-(4-((2'-chloro-4',4'-difluoro-4',5'-dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran]-1-yl)methyl)-3-methyl-1H-pyrazol-1-yl)-3-fluorobenzylidene)-2-methoxyethanamine

Conditions
ConditionsYield
In dichloromethane Molecular sieve;100%
2-(1-((tert-butoxycarbonyl)amino)cyclobutyl)-2-hydroxyacetic acid
1232365-39-7

2-(1-((tert-butoxycarbonyl)amino)cyclobutyl)-2-hydroxyacetic acid

2-methoxyethylamine
109-85-3

2-methoxyethylamine

tert-butyl 1-(1-hydroxy-2-(2-methoxyethylamino)-2-oxoethyl)cyclobutylcarbamate
1311198-98-7

tert-butyl 1-(1-hydroxy-2-(2-methoxyethylamino)-2-oxoethyl)cyclobutylcarbamate

Conditions
ConditionsYield
Stage #1: 2-(1-((tert-butoxycarbonyl)amino)cyclobutyl)-2-hydroxyacetic acid; 2-methoxyethylamine With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide for 0.166667h; Cooling with ice;
Stage #2: With HATU In N,N-dimethyl-formamide for 1h;
100%
4-chloro-3-nitropyridine
13091-23-1

4-chloro-3-nitropyridine

2-methoxyethylamine
109-85-3

2-methoxyethylamine

N-[2-(methyloxy)ethyl]-3-nitro-4-pyridinamine
1040063-55-5

N-[2-(methyloxy)ethyl]-3-nitro-4-pyridinamine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In ethanol at 150℃; for 0.316667h; Microwave vial;100%
2-methoxyethylamine
109-85-3

2-methoxyethylamine

4-fluoro-N-(2-morpholin-4-yl-ethyl)-3-nitro-benzamide

4-fluoro-N-(2-morpholin-4-yl-ethyl)-3-nitro-benzamide

4-{[2-(methyloxy)ethyl]amino}-N-[2-(4-morpholinyl)ethyl]-3-nitrobenzamide
1015992-68-3

4-{[2-(methyloxy)ethyl]amino}-N-[2-(4-morpholinyl)ethyl]-3-nitrobenzamide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In ethanol at 150℃; for 0.0833333h; Microwave irradiation;100%
Methyl 2,2-dimethyl-3-hydroxypropionate
14002-80-3

Methyl 2,2-dimethyl-3-hydroxypropionate

2-methoxyethylamine
109-85-3

2-methoxyethylamine

3-hydroxy-N-(2-methoxyethyl)-2,2-dimethylpropanamide
1093206-21-3

3-hydroxy-N-(2-methoxyethyl)-2,2-dimethylpropanamide

Conditions
ConditionsYield
100%
3,5-dimethylsalicylaldehyde
24623-61-8

3,5-dimethylsalicylaldehyde

2-methoxyethylamine
109-85-3

2-methoxyethylamine

C12H17NO2
1395897-97-8

C12H17NO2

Conditions
ConditionsYield
In methanol for 12h; Reflux;100%
In methanol Reflux;95%
2-methoxyethylamine
109-85-3

2-methoxyethylamine

3,5-dichlorosalicyclaldehyde
90-60-8

3,5-dichlorosalicyclaldehyde

C10H11Cl2NO2
1613543-67-1

C10H11Cl2NO2

Conditions
ConditionsYield
In methanol for 12h; Reflux;100%
3,5-Dibromosalicylaldehyde
90-59-5

3,5-Dibromosalicylaldehyde

2-methoxyethylamine
109-85-3

2-methoxyethylamine

C10H11Br2NO2
847753-50-8

C10H11Br2NO2

Conditions
ConditionsYield
In methanol for 12h; Reflux;100%
3-tert-butyl-2-hydroxybenzaldehyde
24623-65-2

3-tert-butyl-2-hydroxybenzaldehyde

2-methoxyethylamine
109-85-3

2-methoxyethylamine

C14H21NO2
1613543-72-8

C14H21NO2

Conditions
ConditionsYield
In methanol for 12h; Reflux;100%
C14H13N3O3

C14H13N3O3

2-methoxyethylamine
109-85-3

2-methoxyethylamine

C17H20N4O3

C17H20N4O3

Conditions
ConditionsYield
Stage #1: C14H13N3O3 With triethylamine In acetonitrile at 20℃; for 0.0833333h;
Stage #2: With bis(pentafluorophenyl)carbonate In acetonitrile at 20℃; for 0.75h;
Stage #3: 2-methoxyethylamine With triethylamine In acetonitrile at 20℃; for 18h;
100%
7-phenylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid

7-phenylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid

2-methoxyethylamine
109-85-3

2-methoxyethylamine

N-(2-methoxyethyl)-7-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide

N-(2-methoxyethyl)-7-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide

Conditions
ConditionsYield
Stage #1: 7-phenylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid With triethylamine In N,N-dimethyl-formamide at 20℃; for 0.0833333h;
Stage #2: With bis(pentafluorophenyl)carbonate In N,N-dimethyl-formamide at 20℃; for 1h;
Stage #3: 2-methoxyethylamine With triethylamine In N,N-dimethyl-formamide at 20℃; for 24h;
100%
4-Bromo-1-fluoro-2-nitrobenzene
364-73-8

4-Bromo-1-fluoro-2-nitrobenzene

2-methoxyethylamine
109-85-3

2-methoxyethylamine

(4-bromo-2-nitrophenyl)-(2-methoxyethyl)amine

(4-bromo-2-nitrophenyl)-(2-methoxyethyl)amine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In acetonitrile at 85℃; for 16h; Inert atmosphere;100%
In ethanol at 20℃; for 24h;67%
methanesulfonic acid 2-{4-[(4-benzyloxy-phenyl)-methyl-amino]-phenyl}-propyl ester

methanesulfonic acid 2-{4-[(4-benzyloxy-phenyl)-methyl-amino]-phenyl}-propyl ester

2-methoxyethylamine
109-85-3

2-methoxyethylamine

(4-{2-[(2-methoxyethyl)amino]-isopropyl}phenyl)methyl [4(phenylmethoxy)phenyl]amine

(4-{2-[(2-methoxyethyl)amino]-isopropyl}phenyl)methyl [4(phenylmethoxy)phenyl]amine

Conditions
ConditionsYield
With sodium hydrogencarbonate In acetonitrile at 70℃;100%
4-(4-(((tert-butoxycarbonyl)amino)methyl)pyridin-2-yl)benzoic acid

4-(4-(((tert-butoxycarbonyl)amino)methyl)pyridin-2-yl)benzoic acid

2-methoxyethylamine
109-85-3

2-methoxyethylamine

tert-butyl ((2-(4-((2-methoxyethyl)carbamoyl)phenyl)pyridin-4-yl)methyl)

tert-butyl ((2-(4-((2-methoxyethyl)carbamoyl)phenyl)pyridin-4-yl)methyl)

Conditions
ConditionsYield
Stage #1: 4-(4-(((tert-butoxycarbonyl)amino)methyl)pyridin-2-yl)benzoic acid With N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In dichloromethane at 20℃; for 0.166667h;
Stage #2: 2-methoxyethylamine With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 20h;
100%

2-Methoxyethylamine Chemical Properties

Chemistry informtion about 2-Methoxyethylamine (CAS NO.109-85-3) is:
IUPAC Name: 2-Methoxyethanamine
Synonyms: 2-Aminoethyl Methyl Ether ; 2-Methoxyethylamine ; Rarechem Al Bw 0200 ; O-Methylethanolamine ; 1-Methoxy-2-Aminoethane ; 2-Methoxy-Ethanamin ; 2-Methoxyethanamine ; 2-Methoxy-Ethylamin
MF: C3H9NO
MW: 75.11
EINECS: 203-712-1 
Density: 0.852 g/cm3
Melting Point: -82 °C 
Flash Point: 9.4 °C
Boiling Point: 95 °C at 760 mmHg
Vapour Pressure: 46.3 mmHg at 25°C
Enthalpy of Vaporization: 33.47 kJ/mol
Refractive Index: n20/D 1.406(lit.)
Storage temp.: Flammables area
BRN: 741854
Following is the molecular structure of 2-Methoxyethylamine (CAS NO.109-85-3) is:

2-Methoxyethylamine Uses

2-Methoxyethylamine (CAS NO.109-85-3) was used for synthetic intermediates.

2-Methoxyethylamine Production

Preparation Products is Bis(2-Methoxyethyl)Amine .

2-Methoxyethylamine Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 400mg/kg (400mg/kg)   National Technical Information Service. Vol. AD691-490,
mouse LDLo oral 1600mg/kg (1600mg/kg) behavioral: tremor behavioral: muscle weakness behavioral: ataxia National Technical Information Service. Vol. OTS0546426,
rat LDLo oral 1600mg/kg (1600mg/kg) behavioral: muscle weakness lungs, thorax, or respiration: dyspnea lungs, thorax, or respiration: cyanosis National Technical Information Service. Vol. OTS0546426,

2-Methoxyethylamine Consensus Reports

Reported in EPA TSCA Inventory.

2-Methoxyethylamine Safety Profile

Poison by intraperitoneal route. When heated to decomposition it emits toxic fumes of NOx. See also AMINES
Hazard Codes:
FlammableF
CorrosiveC
Risk Statements:
R11:Highly flammable. 
R34:Causes burns.
Safety Statements:
S16:Keep away from sources of ignition. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2733 3/PG 2
WGK Germany: 3
RTECS: KR8750000
HazardClass: 3
PackingGroup: II

2-Methoxyethylamine Analytical Methods

By glycol monomethyl ether and ammonia in the nickel or alumina catalysts under high-temperature dehydration in, or methicillin-acetonitrile nickel to be catalytic hydrogenation.

2-Methoxyethylamine Specification

2-Methoxyethylamine (CAS NO.109-85-3) is a clear colorles liquid. It combustible and can soluble in ethanol and ether.

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