4-(Piperidin-4-yl)morpholine supplier

Name
4-(PIPERIDIN-4-YL)-MORPHOLINE
EINECS 627-580-3
CAS No. 53617-35-9
Article Data18
CAS DataBase
Density 1.034 g/cm³
Solubility
Melting Point 40-43ºC
Formula C₉H₁₈N₂O
Boiling Point 256.341 °C at 760 mmHg
Molecular Weight 170.255
Flash Point 108.832 °C
Transport Information
Appearance
Safety 26-36-36/37/39
Risk Codes Xi:Irritant;
Molecular Structure
Hazard Symbols R36/37/38:;
Synonyms Morpholine,4-(4-piperidyl)- (7CI);4-(Morpholin-4-yl)piperidine;4-Morpholinopiperidine;
PSA 24.50000
LogP 1.94130

Synthetic route

: 415967-79-2
4-(1-benzyl-piperidin-4-yl)-morpholine

: 53617-35-9
4-(piperidin-4-yl)morpholine

Conditions

Conditions	Yield
With palladium on activated charcoal; hydrogen In isopropyl alcohol at 80℃; under 3750.38 Torr; for 7h; Reagent/catalyst; Autoclave;	100%
With palladium on activated charcoal; hydrogen In methanol at 20℃; under 3750.38 Torr; for 6h;	97.6%
With hydrogen; palladium 10% on activated carbon In methanol at 20℃; under 2585.81 Torr; for 18h;	93%
With hydrogenchloride; Pd(OH)2 In methanol	932 mg (91%)
With hydrogenchloride; Pd(OH)2 In methanol	932 mg (91%)

: 4-(1-benzylpiperidin-4-yl)morpholine dihydrochloride

: 53617-35-9
4-(piperidin-4-yl)morpholine

Conditions

Conditions	Yield
Stage #1: 4-(1-benzylpiperidin-4-yl)morpholine dihydrochloride With potassium carbonate In tert-butyl alcohol at 60℃; for 0.5h; pH=>11; Stage #2: With palladium 10% on activated carbon In tert-butyl alcohol at 50℃; for 8h; pH=>11;	91.6%
Stage #1: 4-(1-benzylpiperidin-4-yl)morpholine dihydrochloride With potassium carbonate In water; tert-butyl alcohol at 45℃; Industrial scale; Stage #2: With hydrogen In tert-butyl alcohol at 60℃; under 3000.3 Torr; Industrial scale;	88%

: 125541-20-0
tert-butyl 4-(morpholin-4-yl)piperidine-1-carboxylate

: 53617-35-9
4-(piperidin-4-yl)morpholine

Conditions

Conditions	Yield
With trifluoroacetic acid In dichloromethane at 20℃; for 6h;	79%
With trifluoroacetic acid In dichloromethane at 20℃; for 2h;
With hydrogenchloride In methanol at 40℃; for 12h;	1.52 g
With trifluoroacetic acid In dichloromethane at 20℃;	3 g

: 110-91-8
morpholine

: 3612-20-2
1-phenylmethyl-4-piperidone

A: 53617-35-9
4-(piperidin-4-yl)morpholine

B: 415967-79-2
4-(1-benzyl-piperidin-4-yl)-morpholine

Conditions

Conditions	Yield
With 10 wt% Pd(OH)2 on carbon; hydrogen at 80℃; under 3750.38 Torr; for 4h; Reagent/catalyst; Time; Autoclave;	A 19.7% B 77.5%

...Expand

: 110-91-8
morpholine

: 79099-07-3
N-tert-butyloxycarbonylpiperidin-4-one

: 53617-35-9
4-(piperidin-4-yl)morpholine

Conditions

Conditions	Yield
With sodium tris(acetoxy)borohydride; acetic acid In dichloromethane at 0 - 20℃; for 16h;	74%
With sodium tris(acetoxy)borohydride; acetic acid In dichloromethane at 0 - 20℃; for 16h;	74%
Stage #1: morpholine; N-tert-butyloxycarbonylpiperidin-4-one With titanium(IV) isopropylate In tetrahydrofuran at 20℃; for 1h; Stage #2: With sodium cyanoborohydride In tetrahydrofuran; ethanol at 20℃; Stage #3: With water In tetrahydrofuran; ethanol for 0.5h;

: 2767-91-1
4-morpholinopyridine

: 53617-35-9
4-(piperidin-4-yl)morpholine

Conditions

Conditions	Yield
With hydrogen; ruthenium(IV) oxide

: 110-91-8
morpholine

: 67-63-0
isopropyl alcohol

: 29976-53-2
N-ethoxycarbonyl-4-piperidone

: 53617-35-9
4-(piperidin-4-yl)morpholine

Conditions

Conditions	Yield
With potassium hydroxide; sodium borohydrid; toluene-4-sulfonic acid In ethanol; toluene

...Expand

: 186650-77-1
4-(4-morpholinopiperidin-1-yl)benzonitrile

A: 1194-02-1
4-fluorobenzonitrile

B: 53617-35-9
4-(piperidin-4-yl)morpholine

: 334942-09-5
benzyl 4-morpholin-4-ylpiperidine-1-carboxylate

: 53617-35-9
4-(piperidin-4-yl)morpholine

Conditions

Conditions	Yield
With hydrogen

: 3612-20-2
1-phenylmethyl-4-piperidone

: 53617-35-9
4-(piperidin-4-yl)morpholine

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: toluene / 110 °C / Industrial scale 1.2: Raney nickel / 60 °C / 3000.3 Torr / Industrial scale 1.3: 50 °C / Industrial scale 2.1: potassium carbonate / water; tert-butyl alcohol / 45 °C / Industrial scale 2.2: 60 °C / 3000.3 Torr / Industrial scale View Scheme
Multi-step reaction with 2 steps 1: hydrogen; platinum on activated charcoal / 8 h / 80 °C / 3750.38 Torr / Autoclave 2: hydrogen; palladium on activated charcoal / isopropyl alcohol / 7 h / 80 °C / 3750.38 Torr / Autoclave View Scheme
Multi-step reaction with 2 steps 1: sodium tris(acetoxy)borohydride; acetic acid / dichloromethane / 3 h / 20 °C 2: palladium on activated charcoal; hydrogen / methanol / 6 h / 20 °C / 3750.38 Torr View Scheme

: 79099-07-3
N-tert-butyloxycarbonylpiperidin-4-one

: 53617-35-9
4-(piperidin-4-yl)morpholine

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: palladium 10% on activated carbon; hydrogen / methanol 2: trifluoroacetic acid / dichloromethane / 2 h / 20 °C View Scheme
Multi-step reaction with 2 steps 1: acetic acid; sodium tris(acetoxy)borohydride / dichloromethane / 2 h / 20 °C / Cooling 2: trifluoroacetic acid / dichloromethane / 6 h / 20 °C View Scheme
Multi-step reaction with 2 steps 1: acetic acid; sodium tris(acetoxy)borohydride / dichloromethane / 16 h / 0 - 20 °C 2: hydrogenchloride / methanol / 12 h / 40 °C View Scheme
Multi-step reaction with 2 steps 1.1: acetic acid / 1,2-dichloro-ethane / 0.17 h / 20 °C 1.2: 20 °C 2.1: trifluoroacetic acid / dichloromethane / 20 °C View Scheme

: 5382-16-1
4-HYDROXYPIPERIDINE

: 53617-35-9
4-(piperidin-4-yl)morpholine

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1.1: sodium hydroxide; water / 1,4-dioxane / 0 - 20 °C 2.1: pyridinium chlorochromate; SiO2 / dichloromethane / 2 h / 20 °C 3.1: acetic acid / 1,2-dichloro-ethane / 0.17 h / 20 °C 3.2: 20 °C 4.1: trifluoroacetic acid / dichloromethane / 20 °C View Scheme

: 109384-19-2
t-butyl 4-hydroxy piperidine-1-carboxylate

: 53617-35-9
4-(piperidin-4-yl)morpholine

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: pyridinium chlorochromate; SiO2 / dichloromethane / 2 h / 20 °C 2.1: acetic acid / 1,2-dichloro-ethane / 0.17 h / 20 °C 2.2: 20 °C 3.1: trifluoroacetic acid / dichloromethane / 20 °C View Scheme

: 19099-93-5
benzyl 4-oxo-1-piperidinecarboxylate

: 53617-35-9
4-(piperidin-4-yl)morpholine

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: titanium(IV) isopropylate 2: hydrogen View Scheme

: 1107658-97-8
5-(3-benzofuran-2-yl-phenyl)-1,4-dimethyl-1H-pyrazole-3-carboxylic acid

: 53617-35-9
4-(piperidin-4-yl)morpholine

: 1107656-39-2
[5-(3-Benzofuran-2-yl-phenyl)-1,4-dimethyl-1H-pyrazol-3-yl]-(4-morpholin-4-yl-piperidin-1-yl)-methanone

Conditions

Conditions	Yield
Stage #1: 5-(3-benzofuran-2-yl-phenyl)-1,4-dimethyl-1H-pyrazole-3-carboxylic acid With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane at 20℃; for 1h; Stage #2: 4-(piperidin-4-yl)morpholine With triethylamine In dichloromethane at 0℃; for 3h;	100%

: potassium (chloromethyl)trifluoroborate

: 53617-35-9
4-(piperidin-4-yl)morpholine

: C10H19BF3N2O(1-)*H(1+)

Conditions

Conditions	Yield
In tert-Amyl alcohol at 110℃; Inert atmosphere;	100%

: 76-05-1
trifluoroacetic acid

: 53617-35-9
4-(piperidin-4-yl)morpholine

: 436099-97-7
4-piperidin-4-yl-morpholine bis-trifluoroacetate

Conditions

Conditions	Yield
In dichloromethane at 20℃; for 1h;	98%

: 1256579-48-2
trifluoro-methane sulfonic acid 9-bromo-3-cyano-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazol-8-yl ester

: 53617-35-9
4-(piperidin-4-yl)morpholine

: 1256579-62-0
6,6-dimethyl-9-bromo-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile

Conditions

Conditions	Yield
In 1-methyl-pyrrolidin-2-one at 120℃; for 3h;	98%
With N-methylcyclohexylamine at 80 - 90℃; Temperature; Reagent/catalyst; Large scale;	78.6%

: 1,1-dimethyl-6-ethyl-1,2,3,4-tetrahydro-2-oxo-7-naphthyltriflate

: 53617-35-9
4-(piperidin-4-yl)morpholine

: 1,1-dimethyl-6-ethyl-7-[4-(morpholin-4-yl)piperidine-1-yl]-3,4-dihydro-2-naphthalenone

Conditions

Conditions	Yield
With sodium methylate In 1,4-dioxane at 90℃; for 18h; Solvent; Temperature; Reagent/catalyst;	97%

: 1336964-71-6
methyl 3-(bromomethyl)-6-chloro-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate

: 53617-35-9
4-(piperidin-4-yl)morpholine

: 1336964-72-7
methyl 6-chloro-3-{[4-(4-morpholinyl)-1-piperidinyl]methyl}-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate

Conditions

Conditions	Yield
Stage #1: 4-(piperidin-4-yl)morpholine With potassium carbonate In dichloromethane at 20℃; for 0.5h; Stage #2: methyl 3-(bromomethyl)-6-chloro-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate In dichloromethane at 20℃; for 24h;	96%

: 5-[(ethoxycarbonyl)methyl]-2-ethylphenyl trifluoromethanesulfonate

: 53617-35-9
4-(piperidin-4-yl)morpholine

: 2-{4-ethyl-3-[4-(morpholin-4-yl)piperidin-1-yl]phenyl}acetate

Conditions

Conditions	Yield
With sodium methylate In N,N-dimethyl-formamide at 100℃; for 12h; Concentration; Temperature; Reagent/catalyst; Solvent; Green chemistry;	96%

: 1257295-04-7
4-(8-(bromomethyl)-2-chloro-9-methyl-9H-purin-6-yl)morpholine

: 53617-35-9
4-(piperidin-4-yl)morpholine

: 1257296-26-6
4-(1-((2-chloro-9-methyl-6-morpholino-9H-purin-8-yl)methyl)piperidin-4-yl)morpholine

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 18h;	95%

: 1336904-99-4
methyl 3-(bromomethyl)-7-[(2-methylpropyl)oxy]-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate

: 53617-35-9
4-(piperidin-4-yl)morpholine

: 1336966-25-6
methyl 7-[(2-methylpropyl)oxy]-3-{[4-(4-morpholinyl)-1-piperidinyl]methyl}-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate

Conditions

Conditions	Yield
With potassium carbonate In acetonitrile for 3h;	95%

: 50-00-0
formaldehyd

: 939-69-5
2-cyano-6-hydroxybenzothiazole

: 53617-35-9
4-(piperidin-4-yl)morpholine

: 6-hydroxy-7-[[4-(morpholin-4-yl)piperidin-1-yl]methyl]-1,3-benzothiazole-2-carbonitrile

Conditions

Conditions	Yield
Stage #1: formaldehyd; 4-(piperidin-4-yl)morpholine In acetonitrile at 80℃; for 1h; Stage #2: 2-cyano-6-hydroxybenzothiazole In acetonitrile at 80℃;	95%

...Expand

: 5-[2-(ethoxycarbonyl)propan-2-yl]-2-ethylphenyl trifluoromethanesulfonate

: 53617-35-9
4-(piperidin-4-yl)morpholine

: ethyl 2-{4-ethyl-3-[4-(morpholine-4-yl)piperidine-1-yl]phenyl}-2-methylpropionate

Conditions

Conditions	Yield
With sodium t-butanolate In toluene at 90℃; for 18h; Solvent; Temperature; Reagent/catalyst;	95%

: 7-benzyl-2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidine

: 53617-35-9
4-(piperidin-4-yl)morpholine

: 4-(1-(7-benzyl-2-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl)morpholine

Conditions

Conditions	Yield
With triethylamine In ethanol at 80℃; for 0.25h; Microwave irradiation; Sealed tube;	95%

: 4-(2-(2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)ethyl)morpholine

: 53617-35-9
4-(piperidin-4-yl)morpholine

: 4-(2-(2-chloro-4-(4-morpholinopiperidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)ethyl)morpholine

Conditions

Conditions	Yield
With triethylamine In ethanol at 80℃; for 0.25h; Microwave irradiation;	95%

: 40422-73-9
1-[4-(2-bromoethyl)phenyl]ethanone

: 53617-35-9
4-(piperidin-4-yl)morpholine

: 4-acetyl-2-(4-morpholin-4-yl-1-piperidinyl)-1-ethylbenzene

Conditions

Conditions	Yield
With potassium tert-butylate In dimethyl sulfoxide at 5 - 80℃; Microwave irradiation;	94.9%

: 866087-24-3
4-(2-oxo-1,2,4,5-tetrahydro-benzo[d][1,3]diazepin-3-yl)-piperidine-1-carboxylic acid (R)-2-(4-benzyloxy-3,5-dimethyl-phenyl)-1-carboxy-ethyl ester

: 53617-35-9
4-(piperidin-4-yl)morpholine

: 2-oxoethyl (1R)-4-(1,2,4,5-tetrahydro-2-oxo-3H-1,3-benzodiazepin-3-yl)-1-[[3,5-dimethyl-4-(phenylmethoxy)phenyl]methyl]-2-[4-(4-morpholinyl)-1-piperidinyl]-1-piperidinecarboxylate

Conditions

Conditions	Yield
With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; triethylamine In tetrahydrofuran; ethyl acetate at 0 - 20℃; for 1h;	94%

: 911693-62-4
3-[8-(2,6-difluorophenyl)-2-(methylsulfinyl)-7-oxo-5,6,7,8-tetrahydropyrimido[4,5-d]pyrimidin-4-yl]-4-methyl-N-(1-methylethyl)benzamide

: 53617-35-9
4-(piperidin-4-yl)morpholine

: 3-{8-(2,6-difluorophenyl)-2-[4-(4-morpholinyl)-1-piperidinyl]-7-oxo-5,6,7,8-tetrahydropyrimido[4,5-d]pyrimidin-4-yl}-4-methyl-N-(1-methylethyl)benzamide

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran; chloroform at 20℃;	94%
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran; chloroform at 20℃;	94%

: 1,1-dimethyl-3,4-dihydro-6-ethyl-7-bromonaphthalen-2-one

: 53617-35-9
4-(piperidin-4-yl)morpholine

: 1,1-dimethyl-6-ethyl-7-[4-(morpholin-4-yl)piperidine-1-yl]-3,4-dihydro-2-naphthalenone

Conditions

Conditions	Yield
With sodium methylate In N,N-dimethyl-formamide at 100℃; for 8h; Reagent/catalyst; Solvent; Temperature;	92.3%

: 589-15-1
1-bromomethyl-4-bromobenzene

: 53617-35-9
4-(piperidin-4-yl)morpholine

: 496775-18-9
4-(1-(4-bromobenzyl)piperidin-4-yl)morpholine

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran at 20℃; for 44h;	92%

: 9-ethyl-8-iodo-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]-carbazole-3-carbonitrile

: 53617-35-9
4-(piperidin-4-yl)morpholine

: 1256580-46-7
CH5424802

Conditions

Conditions	Yield
With sodium methylate In N,N-dimethyl-formamide at 100℃; for 12h; Reagent/catalyst; Temperature;	92%
With sodium methylate In toluene at 100℃; for 10h; Reagent/catalyst; Solvent;	89%
With potassium tert-butylate; L-proline In 1,4-dioxane at 120℃; for 24h; Reagent/catalyst; Solvent; Temperature; Inert atmosphere;	10.3 g

: 6-((3-fluorobenzyl)amino)imidazo[1,2-b]pyridazine-3-carboxylic acid

: 53617-35-9
4-(piperidin-4-yl)morpholine

: (6-((3-fluorobenzyl)amino)imidazo[1,2-b]pyridazin-3-yl)(4-morpholinopiperidin-1-yl)methanone

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 60℃; for 1h;	91.39%

: tert-butyl 4-(4-ethyl-3-iodo-phenyl)-4-methyl-3-oxo-pentanoate

: 53617-35-9
4-(piperidin-4-yl)morpholine

: tert-butyl 4-{4-ethyl-3-[4-(morpholin-4-yl)piperidin-1-yl]phenyl}-4-methyl-3-oxopentanoate

Conditions

Conditions	Yield
With sodium ethanolate In toluene at 110℃; for 6h; Reagent/catalyst; Solvent; Temperature;	91%
With iron(III)-acetylacetonate; caesium carbonate; copper(II) oxide In N,N-dimethyl-formamide at 90℃; for 20h; Reagent/catalyst; Solvent; Temperature; Sealed tube; Inert atmosphere; Green chemistry;	82%

: 6-ethyl-1,2,3,4-tetrahydro-2-oxo-7-naphthalyl trifluoromethanesulfonate

: 53617-35-9
4-(piperidin-4-yl)morpholine

: 6-ethyl-7-[4-(morpholin-4-yl)piperidin-1-yl]-3,4-dihydro-2-naphthalenone

Conditions

Conditions	Yield
With sodium methylate In N,N-dimethyl-formamide at 100℃; for 8h; Solvent; Temperature; Reagent/catalyst;	91%

: 1336965-10-6
methyl 3-(bromomethyl)-6-(trifluoromethyl)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate

: 53617-35-9
4-(piperidin-4-yl)morpholine

: 1336965-12-8
methyl 3-{[4-(4-morpholinyl)-1-piperidinyl]methyl}-6-(trifluoromethyl)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate

Conditions

Conditions	Yield
With potassium carbonate In acetonitrile for 5h; Reflux;	90%

: 1336965-98-0
methyl 3-(bromomethyl)-6-chloro-7-(methyloxy)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate

: 53617-35-9
4-(piperidin-4-yl)morpholine

: 1336965-99-1
methyl 6-chloro-7-(methyloxy)-3-{[4-(4-morpholinyl)-1-piperidinyl]methyl}-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate

Conditions

Conditions	Yield
In acetonitrile at 20℃; for 3h;	90%

: 6-ethyl-7-bromo-3,4-dihydro-2-naphthalenone

: 53617-35-9
4-(piperidin-4-yl)morpholine

: 6-ethyl-7-[4-(morpholin-4-yl)piperidin-1-yl]-3,4-dihydro-2-naphthalenone

Conditions

Conditions	Yield
With sodium isopropylate In 1,4-dioxane at 90℃; for 12h; Temperature; Reagent/catalyst; Solvent;	90%

: (Z)-5-(3-phenoxybenzylidene)-2-(methylthio)-3H-imidazol-4(5H)-one

: 53617-35-9
4-(piperidin-4-yl)morpholine

: (Z)-5-(3-phenoxybenzylidene)-2-(4-morpholinopiperidin-1-yl)imidazol-4(5H)-one hydrochloride

Conditions

Conditions	Yield
Stage #1: (Z)-5-(3-phenoxybenzylidene)-2-(methylthio)-3H-imidazol-4(5H)-one; 4-(piperidin-4-yl)morpholine at 120 - 130℃; for 0.25h; Stage #2: In ethanol Reflux; Stage #3: With hydrogenchloride	89.26%

: 1274038-52-6
1-bromo-3-{[(4-methoxybenzyl)oxy]methyl}benzene

: 53617-35-9
4-(piperidin-4-yl)morpholine

: 4-[1-(3-{[(4-methoxybenzyl)oxy]methyl}phenyl)piperidin-4-yl]morpholine

Conditions

Conditions	Yield
With tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate In toluene at 100℃; for 1h; Buchwald-Hartwig Coupling; Inert atmosphere;	89%

: 1335116-56-7
methyl 3-(bromomethyl)-6-(ethylsulfonyl)-7-(methyloxy)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate

: 53617-35-9
4-(piperidin-4-yl)morpholine

: 1335116-59-0
methyl 6-(ethylsulfonyl)-7-(methyloxy)-3-{[4-(4-morpholinyl)-1-piperidinyl]methyl}-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate

Conditions

Conditions	Yield
In acetonitrile at 20℃; for 3h;	87%

4-(Piperidin-4-yl)morpholine Chemical Properties

Molecular Structure of 4-(PIPERIDIN-4-YL)-MORPHOLINE(53617-35-9):

IUPAC Name:4-piperidin-4-ylmorpholine
Molecular Formula:C₉H₁₈N₂O
Molecular Weight:170.252020 g/mol
Melting Point:40-43 °C(lit.)
Density:1.033 g/cm³
Flash Point:108.8 °C
Enthalpy of Vaporization:49.39 kJ/mol
Boiling Point:256.3 °C at 760 mmHg
Vapour Pressure:0.0155 mmHg at 25 °C
Water Solubility:7.111e+005 mg/L at 25 °C
Synonyms of 4-(PIPERIDIN-4-YL)-MORPHOLINE(53617-35-9):
CHEMBRDG-BB 4004473;4-MORPHOLINOPIPERIDINE;AKOS BB-9182;TIMTEC-BB SBB010091;4-Morpholino-piperidin;4-(PIPERIDIN-4-YL)-MORPHOLINE >98%;4-MORPHOLINO-PIPERDINEDIHYDROCHLORIDE
Categories of 4-(PIPERIDIN-4-YL)-MORPHOLINE(53617-35-9):
Building Blocks;Heterocyclic Building Blocks;Piperidines

4-(Piperidin-4-yl)morpholine Safety Profile

Safety Information of 4-(PIPERIDIN-4-YL)-MORPHOLINE(53617-35-9):
Hazard Codes:Xi

Risk Statements:36/37/38
36/37/38:Irritating to eyes, respiratory system and skin
Safety Statements:26-36
26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36:Wear suitable protective clothing
WGK Germany:3
Hazard Note:Irritant

Product Name

4-(PIPERIDIN-4-YL)-MORPHOLINE

Synthetic route

4-(Piperidin-4-yl)morpholine Chemical Properties

4-(Piperidin-4-yl)morpholine Safety Profile

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